| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leanne K Wilkins, Todd A Girard, Katherine A Herdman, Bruce K Christensen, Jelena King, Michael Kiang, Veronique D Bohbo. Hippocampal activation and memory performance in schizophrenia depend on strategy use in a virtual maze. Psychiatry research. Neuroimaging. vol 268. 2018-04-24. PMID:28780430. |
ssd (schizophrenia and schizoaffective disorder) participants who adopted a spatial strategy performed more poorly on the 4/8vm task and had less hippocampal activation than healthy comparison participants using either strategy as well as ssd participants using a response strategy. |
2018-04-24 |
2023-08-13 |
human |
| Catherine A Thorn, Michael Popiolek, Eda Stark, Jeremy R Edgerto. Effects of M1 and M4 activation on excitatory synaptic transmission in CA1. Hippocampus. vol 27. issue 7. 2018-04-18. PMID:28422371. |
hippocampal networks are particularly susceptible to dysfunction in many neurodegenerative diseases and neuropsychiatric disorders including alzheimer's disease, lewy body dementia, and schizophrenia. |
2018-04-18 |
2023-08-13 |
rat |
| Kathryn Hill, Nicolas Bolo, Suraj Sarvode Mothi, Paulo Lizano, Synthia Guimond, Neeraj Tandon, Elena Molokotos, Matcheri Keshava. Subcortical surface shape in youth at familial high risk for schizophrenia. Psychiatry research. Neuroimaging. vol 267. 2018-04-11. PMID:28734178. |
to evaluate the relationships between subcortical structure, schizotypy, and cognitive function, we assessed shape and volume of the hippocampus, amygdala and thalamus in untreated youth at familial high risk for schizophrenia (hrsz). |
2018-04-11 |
2023-08-13 |
Not clear |
| Jia Tian, Fei Geng, Feng Gao, Yi-Hua Chen, Ji-Hong Liu, Jian-Lin Wu, Yu-Jie Lan, Yuan-Ning Zeng, Xiao-Wen Li, Jian-Ming Yang, Tian-Ming Ga. Down-Regulation of Neuregulin1/ErbB4 Signaling in the Hippocampus Is Critical for Learning and Memory. Molecular neurobiology. vol 54. issue 6. 2018-04-09. PMID:27295274. |
hippocampal function is important for learning and memory, and dysfunction of the hippocampus has been linked to the pathophysiology of neuropsychiatric diseases such as schizophrenia. |
2018-04-09 |
2023-08-13 |
Not clear |
| S Papiol, D Popovic, D Keeser, A Hasan, T Schneider-Axmann, F Degenhardt, M J Rossner, H Bickeböller, A Schmitt, P Falkai, B Malcho. Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia. Translational psychiatry. vol 7. issue 6. 2018-03-26. PMID:28654095. |
polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia. |
2018-03-26 |
2023-08-13 |
Not clear |
| S Papiol, D Popovic, D Keeser, A Hasan, T Schneider-Axmann, F Degenhardt, M J Rossner, H Bickeböller, A Schmitt, P Falkai, B Malcho. Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia. Translational psychiatry. vol 7. issue 6. 2018-03-26. PMID:28654095. |
preliminary studies suggest that, besides improving cognition, aerobic exercise might increase hippocampal volume in schizophrenia patients; however, results are not consistent. |
2018-03-26 |
2023-08-13 |
Not clear |
| S Papiol, D Popovic, D Keeser, A Hasan, T Schneider-Axmann, F Degenhardt, M J Rossner, H Bickeböller, A Schmitt, P Falkai, B Malcho. Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia. Translational psychiatry. vol 7. issue 6. 2018-03-26. PMID:28654095. |
the secondary analysis presented here aimed to determine the modulatory role of schizophrenia polygenic risk scores (prss) on volume changes in the total hippocampus and cornu ammonis (ca) 1, ca2/3, ca4/dentate gyrus (dg) and subiculum over time. |
2018-03-26 |
2023-08-13 |
Not clear |
| Sibin Li, Lanlan Ma, Yuchen Wang, Xuejiao Wang, Yingzhuo Li, Ling Qi. Auditory steady-state responses in primary and non-primary regions of the auditory cortex in neonatal ventral hippocampal lesion rats. PloS one. vol 13. issue 2. 2018-03-19. PMID:29415081. |
the neonatal ventral hippocampal lesion (nvhl) rat is a widely used model to investigate the neurodevelopmental mechanisms of schizophrenia. |
2018-03-19 |
2023-08-13 |
rat |
| L A Feldcamp, P C Boutros, R Raymond, P J Fletcher, J N Nobrega, A H C Won. Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse. Translational psychiatry. vol 7. issue 5. 2018-02-20. PMID:28485732. |
we examined several brain regions involved in ppi and schizophrenia: hippocampus, striatum, and brainstem, found a number of transcripts that showed good correlation with ppi level, and confirmed this with real-time quantitative pcr. |
2018-02-20 |
2023-08-13 |
mouse |
| Xinyi Fan, Yilin Song, Yuanlin Ma, Song Zhang, Guihua Xiao, Lili Yang, Huiren Xu, Dai Zhang, Xinxia Ca. In Situ Real-Time Monitoring of Glutamate and Electrophysiology from Cortex to Hippocampus in Mice Based on a Microelectrode Array. Sensors (Basel, Switzerland). vol 17. issue 1. 2018-02-05. PMID:28042814. |
changes in the structure and function of the hippocampus contribute to epilepsy, schizophrenia and other neurological or mental disorders of the brain. |
2018-02-05 |
2023-08-13 |
mouse |
| Cheng Chang, Chuan Huang, Naiyun Zhou, Shawn Xiang Li, Lawrence Ver Hoef, Yi Ga. The bumps under the hippocampus. Human brain mapping. vol 39. issue 1. 2018-01-23. PMID:29058349. |
this method opens possibilities of future research on the hippocampus and other sub-cortical structural morphometry correlating the degree of dentation with a range of diseases including epilepsy, alzheimer's disease, and schizophrenia. |
2018-01-23 |
2023-08-13 |
Not clear |
| J J Donegan, J A Tyson, S Y Branch, M J Beckstead, S A Anderson, D J Lodg. Stem cell-derived interneuron transplants as a treatment for schizophrenia: preclinical validation in a rodent model. Molecular psychiatry. vol 22. issue 10. 2018-01-19. PMID:27480492. |
an increasing literature suggests that schizophrenia is associated with a reduction in hippocampal interneuron function. |
2018-01-19 |
2023-08-13 |
Not clear |
| J J Donegan, J A Tyson, S Y Branch, M J Beckstead, S A Anderson, D J Lodg. Stem cell-derived interneuron transplants as a treatment for schizophrenia: preclinical validation in a rodent model. Molecular psychiatry. vol 22. issue 10. 2018-01-19. PMID:27480492. |
thus, we posit that stem cell-derived interneuron transplants may be an effective therapeutic strategy to reduce hippocampal hyperactivity and attenuate behavioral deficits in schizophrenia. |
2018-01-19 |
2023-08-13 |
Not clear |
| J J Donegan, J A Tyson, S Y Branch, M J Beckstead, S A Anderson, D J Lodg. Stem cell-derived interneuron transplants as a treatment for schizophrenia: preclinical validation in a rodent model. Molecular psychiatry. vol 22. issue 10. 2018-01-19. PMID:27480492. |
here we used a dual-reporter embryonic stem cell line to generate enriched populations of parvalbumin (pv)- or somatostatin (sst)-positive interneurons, which were transplanted into the ventral hippocampus of the methylazoxymethanol rodent model of schizophrenia. |
2018-01-19 |
2023-08-13 |
Not clear |
| New Fei Ho, Daphne J Holt, Mike Cheung, Juan Eugenio Iglesias, Alex Goh, Mingyuan Wang, Joseph Kw Lim, Joshua de Souza, Joann S Poh, Yuen Mei See, Alison R Adcock, Stephen J Wood, Michael Wl Chee, Jimmy Lee, Juan Zho. Progressive Decline in Hippocampal CA1 Volume in Individuals at Ultra-High-Risk for Psychosis Who Do Not Remit: Findings from the Longitudinal Youth at Risk Study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 6. 2018-01-19. PMID:28079061. |
prior work has shown that the volume of ca1, a subfield of the hippocampus, is selectively reduced in the early stages of schizophrenia. |
2018-01-19 |
2023-08-13 |
human |
| Anne Marie Brad. The Neonatal Ventral Hippocampal Lesion (NVHL) Rodent Model of Schizophrenia. Current protocols in neuroscience. vol 77. 2018-01-12. PMID:27696361. |
the neonatal ventral hippocampal lesion (nvhl) rodent model of schizophrenia. |
2018-01-12 |
2023-08-13 |
rat |
| Helena Buchtová, Iveta Fajnerová, Aleš Stuchlík, Štěpán Kubí. Acute systemic MK-801 induced functional uncoupling between hippocampal areas CA3 and CA1 with distant effect in the retrosplenial cortex. Hippocampus. vol 27. issue 2. 2018-01-10. PMID:27806441. |
hippocampal and retrosplenial damage is found in patients with schizophrenia alongside cognitive deficits affecting relational memory. |
2018-01-10 |
2023-08-13 |
rat |
| Philip Lr Gaskin, Maria Toledo-Rodriguez, Stephen Ph Alexander, Kevin Cf Fon. Down-Regulation of Hippocampal Genes Regulating Dopaminergic, GABAergic, and Glutamatergic Function Following Combined Neonatal Phencyclidine and Post-Weaning Social Isolation of Rats as a Neurodevelopmental Model for Schizophrenia. The international journal of neuropsychopharmacology. vol 19. issue 11. 2018-01-08. PMID:27382048. |
down-regulation of hippocampal genes regulating dopaminergic, gabaergic, and glutamatergic function following combined neonatal phencyclidine and post-weaning social isolation of rats as a neurodevelopmental model for schizophrenia. |
2018-01-08 |
2023-08-13 |
rat |
| Yijuan Du, Anthony A Grac. Loss of Parvalbumin in the Hippocampus of MAM Schizophrenia Model Rats Is Attenuated by Peripubertal Diazepam. The international journal of neuropsychopharmacology. vol 19. issue 11. 2018-01-08. PMID:27432008. |
loss of parvalbumin in the hippocampus of mam schizophrenia model rats is attenuated by peripubertal diazepam. |
2018-01-08 |
2023-08-13 |
rat |
| Yijuan Du, Anthony A Grac. Loss of Parvalbumin in the Hippocampus of MAM Schizophrenia Model Rats Is Attenuated by Peripubertal Diazepam. The international journal of neuropsychopharmacology. vol 19. issue 11. 2018-01-08. PMID:27432008. |
loss of parvalbumin interneurons in the hippocampus is a robust finding in schizophrenia brains. |
2018-01-08 |
2023-08-13 |
rat |