| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Igor Nenadic, Raka Maitra, Soumyajit Basu, Maren Dietzek, Nils Schönfeld, Carsten Lorenz, Alexander Gussew, G Paul Amminger, Patrick McGorry, Jürgen R Reichenbach, Heinrich Sauer, Christian Gaser, Stefan Smesn. Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26088723. |
associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia. |
2016-07-12 |
2023-08-13 |
human |
| Igor Nenadic, Raka Maitra, Soumyajit Basu, Maren Dietzek, Nils Schönfeld, Carsten Lorenz, Alexander Gussew, G Paul Amminger, Patrick McGorry, Jürgen R Reichenbach, Heinrich Sauer, Christian Gaser, Stefan Smesn. Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26088723. |
hippocampal pathology has been shown to be central to the pathophysiology of schizophrenia and a putative risk marker for developing psychosis. |
2016-07-12 |
2023-08-13 |
human |
| Igor Nenadic, Raka Maitra, Soumyajit Basu, Maren Dietzek, Nils Schönfeld, Carsten Lorenz, Alexander Gussew, G Paul Amminger, Patrick McGorry, Jürgen R Reichenbach, Heinrich Sauer, Christian Gaser, Stefan Smesn. Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26088723. |
we applied both (1)h mrs (proton magnetic resonance spectroscopy) at 3tesla and voxel-based morphometry (vbm) of high-resolution brain structural images in order to study the association of the metabolites glutamate (glu) and n-acetyl-aspartate (naa) in the hippocampus with whole-brain morphometry in 31 persons at ultra-high-risk for psychosis (uhr), 18 first-episode schizophrenia patients (sz), and 42 healthy controls (all subjects being neuroleptic-naïve). |
2016-07-12 |
2023-08-13 |
human |
| Igor Nenadic, Raka Maitra, Soumyajit Basu, Maren Dietzek, Nils Schönfeld, Carsten Lorenz, Alexander Gussew, G Paul Amminger, Patrick McGorry, Jürgen R Reichenbach, Heinrich Sauer, Christian Gaser, Stefan Smesn. Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26088723. |
significantly diverging associations emerged for uhr subjects hippocampal glutamate showed positive correlation with the left superior frontal cortex, not seen in sz or controls, while in first-episode schizophrenia patients a negative correlation was significant between glutamate and a left prefrontal area. |
2016-07-12 |
2023-08-13 |
human |
| Igor Nenadic, Raka Maitra, Soumyajit Basu, Maren Dietzek, Nils Schönfeld, Carsten Lorenz, Alexander Gussew, G Paul Amminger, Patrick McGorry, Jürgen R Reichenbach, Heinrich Sauer, Christian Gaser, Stefan Smesn. Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26088723. |
our results suggest that associations of hippocampal metabolites in key areas of schizophrenia might vary due to liability to or onset of the disorder. |
2016-07-12 |
2023-08-13 |
human |
| C S Weickert, R Straub, J Kleinman, T Hyde, D Rothmon. Reduced dysbindin (DTNBP1) mRNA in hippocampus of patients with schizophrenia. Acta neuropsychiatrica. vol 18. issue 6. 2016-07-12. PMID:27397329. |
reduced dysbindin (dtnbp1) mrna in hippocampus of patients with schizophrenia. |
2016-07-12 |
2023-08-13 |
Not clear |
| Dominik Strzelecki, Piotr Grzelak, Michał Podgórski, Olga Kałużyńska, Ludomir Stefańczyk, Magdalena Kotlicka-Antczak, Agnieszka Gmitrowic. Comparison of Metabolite Concentrations in the Left Dorsolateral Prefrontal Cortex, the Left Frontal White Matter, and the Left Hippocampus in Patients in Stable Schizophrenia Treated with Antipsychotics with or without Antidepressants. ¹H-NMR Spectroscopy Study. International journal of molecular sciences. vol 16. issue 10. 2016-07-11. PMID:26501256. |
comparison of metabolite concentrations in the left dorsolateral prefrontal cortex, the left frontal white matter, and the left hippocampus in patients in stable schizophrenia treated with antipsychotics with or without antidepressants. |
2016-07-11 |
2023-08-13 |
Not clear |
| Stephan Heckers, Christine Konrad. GABAergic mechanisms of hippocampal hyperactivity in schizophrenia. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25449711. |
gabaergic mechanisms of hippocampal hyperactivity in schizophrenia. |
2016-06-27 |
2023-08-13 |
Not clear |
| Stephan Heckers, Christine Konrad. GABAergic mechanisms of hippocampal hyperactivity in schizophrenia. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25449711. |
schizophrenia is associated with abnormalities of hippocampal structure and function. |
2016-06-27 |
2023-08-13 |
Not clear |
| Stephan Heckers, Christine Konrad. GABAergic mechanisms of hippocampal hyperactivity in schizophrenia. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25449711. |
neuroimaging studies have shown that the hippocampus is hyperactive in schizophrenia. |
2016-06-27 |
2023-08-13 |
Not clear |
| Stephan Heckers, Christine Konrad. GABAergic mechanisms of hippocampal hyperactivity in schizophrenia. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25449711. |
the initial evidence for gabaergic abnormalities of the hippocampus in schizophrenia came from post-mortem studies of interneuron number, protein expression, and gene expression. |
2016-06-27 |
2023-08-13 |
Not clear |
| Stephan Heckers, Christine Konrad. GABAergic mechanisms of hippocampal hyperactivity in schizophrenia. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25449711. |
animal studies of decreased parvalbumin and nmda-receptor function have shown that selective abnormalities of hippocampal interneurons mimic some of the cognitive deficits and clinical features of schizophrenia. |
2016-06-27 |
2023-08-13 |
Not clear |
| Klaus Oliver Schubert, Melanie Föcking, David R Cotte. Proteomic pathway analysis of the hippocampus in schizophrenia and bipolar affective disorder implicates 14-3-3 signaling, aryl hydrocarbon receptor signaling, and glucose metabolism: potential roles in GABAergic interneuron pathology. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25728835. |
proteomic pathway analysis of the hippocampus in schizophrenia and bipolar affective disorder implicates 14-3-3 signaling, aryl hydrocarbon receptor signaling, and glucose metabolism: potential roles in gabaergic interneuron pathology. |
2016-06-27 |
2023-08-13 |
human |
| Klaus Oliver Schubert, Melanie Föcking, David R Cotte. Proteomic pathway analysis of the hippocampus in schizophrenia and bipolar affective disorder implicates 14-3-3 signaling, aryl hydrocarbon receptor signaling, and glucose metabolism: potential roles in GABAergic interneuron pathology. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25728835. |
neuropathological changes of the hippocampus have been associated with psychotic disorders such as schizophrenia and bipolar disorder. |
2016-06-27 |
2023-08-13 |
human |
| Klaus Oliver Schubert, Melanie Föcking, David R Cotte. Proteomic pathway analysis of the hippocampus in schizophrenia and bipolar affective disorder implicates 14-3-3 signaling, aryl hydrocarbon receptor signaling, and glucose metabolism: potential roles in GABAergic interneuron pathology. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25728835. |
we used data from comprehensive difference-in-gel electrophoresis (2-d dige) investigations of postmortem human hippocampus of people with schizophrenia and bipolar disorder, covering the acidic (isoelectric point (pi) between ph4 and 7) and, separately, the basic (pi between ph6 and 11) sub-proteome, for ingenuity pathway analysis (ipa) of implicated protein networks and pathways. |
2016-06-27 |
2023-08-13 |
human |
| Francine M Bene. Building models for postmortem abnormalities in hippocampus of schizophrenics. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25749020. |
postmortem studies have suggested that there is abnormal gabaergic activity in the hippocampus in schizophrenia (sz). |
2016-06-27 |
2023-08-13 |
human |
| Francine M Bene. Building models for postmortem abnormalities in hippocampus of schizophrenics. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25749020. |
in micro-dissected human hippocampal slices, a loss of interneurons and a compensatory upregulation of gabaa receptor binding activity on interneurons, but not pns, has suggested that disinhibitory gaba-to-gaba connections are abnormal in stratum oriens (so) of ca3/2, but not ca1, in schizophrenia. |
2016-06-27 |
2023-08-13 |
human |
| Sunil V Kalmady, Venkataram Shivakumar, S Gautham, Rashmi Arasappa, Dania A Jose, Ganesan Venkatasubramanian, B N Gangadha. Dermatoglyphic correlates of hippocampus volume: Evaluation of aberrant neurodevelopmental markers in antipsychotic-naïve schizophrenia. Psychiatry research. vol 234. issue 1. 2016-06-27. PMID:26385539. |
dermatoglyphic correlates of hippocampus volume: evaluation of aberrant neurodevelopmental markers in antipsychotic-naïve schizophrenia. |
2016-06-27 |
2023-08-13 |
human |
| Sunil V Kalmady, Venkataram Shivakumar, S Gautham, Rashmi Arasappa, Dania A Jose, Ganesan Venkatasubramanian, B N Gangadha. Dermatoglyphic correlates of hippocampus volume: Evaluation of aberrant neurodevelopmental markers in antipsychotic-naïve schizophrenia. Psychiatry research. vol 234. issue 1. 2016-06-27. PMID:26385539. |
the current study examined dermatoglyphic correlates of hippocampal volume in antipsychotic-naïve schizophrenia patients in comparison with matched healthy controls. |
2016-06-27 |
2023-08-13 |
human |
| Francesco Margari, Maria Giuseppina Petruzzelli, Rossana Mianulli, Maria Gloria Campa, Adriana Pastore, Marilina Tampoi. Circulating anti-brain autoantibodies in schizophrenia and mood disorders. Psychiatry research. vol 230. issue 2. 2016-06-24. PMID:26548982. |
we found a significant difference for circulating autoantibodies to hypothalamus, hippocampus and cerebellum and for anti-nuclear autoantibodies in both schizophrenia and mood disorders when compared to the control group. |
2016-06-24 |
2023-08-13 |
rat |