| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Feras Ali Mustaf. Schizophrenia past clozapine: what works? Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277242. |
clozapine is superior to other antipsychotic drugs for treatment of refractory schizophrenia. |
2013-06-12 |
2023-08-12 |
Not clear |
| Arun K Tiwari, Eva J Brandl, Caroline Weber, Olga Likhodi, Clement C Zai, Margaret K Hahn, Jeffrey A Lieberman, Herbert Y Meltzer, James L Kennedy, Daniel J Mülle. Association of a functional polymorphism in neuropeptide Y with antipsychotic-induced weight gain in schizophrenia patients. Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277265. |
because npy is a potent orexigenic peptide stimulating food intake, and genetic variation of the gene has been shown to influence development of obesity, we investigated the impact of npy polymorphisms on antipsychotic-induced bwg.we analyzed 5 polymorphisms in the npy gene (rs10551063, rs16147, rs5573, rs5574, and rs16475) in schizophrenia subjects (n = 226), treated mostly with clozapine and olanzapine for up to 14 weeks. |
2013-06-12 |
2023-08-12 |
human |
| Jong-Hoon Kim, Sang Hoon Yi, Jinyoung Lee, Yong Sik Ki. Effects of clozapine on heart rate dynamics and their relationship with therapeutic response in treatment-resistant schizophrenia. Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277266. |
effects of clozapine on heart rate dynamics and their relationship with therapeutic response in treatment-resistant schizophrenia. |
2013-06-12 |
2023-08-12 |
Not clear |
| Jong-Hoon Kim, Sang Hoon Yi, Jinyoung Lee, Yong Sik Ki. Effects of clozapine on heart rate dynamics and their relationship with therapeutic response in treatment-resistant schizophrenia. Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277266. |
the purpose of the present study was to investigate the effects of clozapine on the nonlinear complexity measures of hrv in patients with treatment-resistant schizophrenia to find novel electrophysiological markers that indicate response to clozapine treatment. |
2013-06-12 |
2023-08-12 |
Not clear |
| Jong-Hoon Kim, Sang Hoon Yi, Jinyoung Lee, Yong Sik Ki. Effects of clozapine on heart rate dynamics and their relationship with therapeutic response in treatment-resistant schizophrenia. Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277266. |
forty patients with treatment-resistant schizophrenia were evaluated during 8 weeks of clozapine monotherapy. |
2013-06-12 |
2023-08-12 |
Not clear |
| Peiyan Wong, Cecilia Chin Roei Chang, Christine E Marx, Marc G Caron, William C Wetsel, Xiaodong Zhan. Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice. PloS one. vol 7. issue 12. 2013-05-30. PMID:23240026. |
it has been shown that the level of pregnenolone is altered in certain brain areas of schizophrenic patients, and clozapine enhances pregnenolone in the cns in rats, suggesting that pregnenolone could be used to treat certain symptoms of schizophrenia. |
2013-05-30 |
2023-08-12 |
mouse |
| Anto P Rajkumar, Balasubramanian Poonkuzhali, Anju Kuruvilla, Molly Jacob, Kuruthukulangara S Jaco. Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. International clinical psychopharmacology. vol 28. issue 1. 2013-05-21. PMID:23104241. |
clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. |
2013-05-21 |
2023-08-12 |
Not clear |
| Anto P Rajkumar, Balasubramanian Poonkuzhali, Anju Kuruvilla, Molly Jacob, Kuruthukulangara S Jaco. Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. International clinical psychopharmacology. vol 28. issue 1. 2013-05-21. PMID:23104241. |
fixed oral doses of clozapine produce up to 45-fold interindividual variability among its serum levels in patients with treatment-resistant schizophrenia. |
2013-05-21 |
2023-08-12 |
Not clear |
| Anto P Rajkumar, Balasubramanian Poonkuzhali, Anju Kuruvilla, Molly Jacob, Kuruthukulangara S Jaco. Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. International clinical psychopharmacology. vol 28. issue 1. 2013-05-21. PMID:23104241. |
we assessed the sociodemographic and clinical profiles, cognition, disability and psychopathology of 101 consecutive patients with treatment-resistant schizophrenia on a stable dose of clozapine, using standard assessment schedules. |
2013-05-21 |
2023-08-12 |
Not clear |
| Ruiling Zhang, Wei Hao, Miao Pan, Chuansheng Wang, Xiuli Zhang, Da Chun Chen, Mei Hong Xiu, Fu De Yang, Thomas R Kosten, Xiang Yang Zhan. The prevalence and clinical-demographic correlates of diabetes mellitus in chronic schizophrenic patients receiving clozapine. Human psychopharmacology. vol 26. issue 6. 2013-05-17. PMID:21826737. |
to examine the prevalence and correlates of diabetes in a large sample of chinese patients with schizophrenia on long-term clozapine treatment, because this population previously has received little systematic study. |
2013-05-17 |
2023-08-12 |
Not clear |
| Ketil Arne Espnes, Kent Ove Heimdal, Olav Spigse. A puzzling case of increased serum clozapine levels in a patient with inflammation and infection. Therapeutic drug monitoring. vol 34. issue 5. 2013-05-14. PMID:22929408. |
a 23-year old male with a history of schizophrenia treated with clozapine 900 mg/d was admitted to the hospital for a gastrointestinal infection. |
2013-05-14 |
2023-08-12 |
Not clear |
| Ya-Wen Lai, Che-Yi Chou, Winston W Shen, Mong-Liang L. Pityriasis rosea-like eruption associated with clozapine: a case report. General hospital psychiatry. vol 34. issue 6. 2013-05-03. PMID:22516218. |
clozapine, a complex neurotransmitter receptor-binding in antipsychotic agent, is usually used for treatment-resistant schizophrenia. |
2013-05-03 |
2023-08-12 |
Not clear |
| Ya-Wen Lai, Che-Yi Chou, Winston W Shen, Mong-Liang L. Pityriasis rosea-like eruption associated with clozapine: a case report. General hospital psychiatry. vol 34. issue 6. 2013-05-03. PMID:22516218. |
we report a 54-year-old male patient with chronic schizophrenia who had received clozapine for 28 days and developed generalized skin rashes, high fever, and elevated values in liver function tests. |
2013-05-03 |
2023-08-12 |
Not clear |
| Jimmi Nielsen, John M Kane, Christoph U Correl. Real-world effectiveness of clozapine in patients with bipolar disorder: results from a 2-year mirror-image study. Bipolar disorders. vol 14. issue 8. 2013-05-03. PMID:23107278. |
clozapine remains the drug of choice for treatment-resistant schizophrenia but the evidence for its use in severe bipolar disorder (bd) remains sparse. |
2013-05-03 |
2023-08-12 |
Not clear |
| A P Rajkumar, B Poonkuzhali, A Kuruvilla, A Srivastava, M Jacob, K S Jaco. Outcome definitions and clinical predictors influence pharmacogenetic associations between HTR3A gene polymorphisms and response to clozapine in patients with schizophrenia. Psychopharmacology. vol 224. issue 3. 2013-04-29. PMID:22700043. |
outcome definitions and clinical predictors influence pharmacogenetic associations between htr3a gene polymorphisms and response to clozapine in patients with schizophrenia. |
2013-04-29 |
2023-08-12 |
Not clear |
| Oliver D Howes, Francis Vergunst, Siobhan Gee, Philip McGuire, Shitij Kapur, David Taylo. Adherence to treatment guidelines in clinical practice: study of antipsychotic treatment prior to clozapine initiation. The British journal of psychiatry : the journal of mental science. vol 201. issue 6. 2013-04-29. PMID:22955007. |
clozapine is the only antipsychotic drug licensed for treatment-resistant schizophrenia but its use is often delayed. |
2013-04-29 |
2023-08-12 |
Not clear |
| Michele Hill, Oliver Freudenreic. Clozapine: key discussion points for prescribers. Clinical schizophrenia & related psychoses. vol 6. issue 4. 2013-04-04. PMID:23302447. |
clozapine is the most effective antipsychotic medication for treatment-refractory schizophrenia and is also approved for suicidality in schizophrenia patients. |
2013-04-04 |
2023-08-12 |
Not clear |
| Margaret K Hahn, Tony Cohn, Celine Teo, Gary Remingto. Topiramate in schizophrenia: a review of effects on psychopathology and metabolic parameters. Clinical schizophrenia & related psychoses. vol 6. issue 4. 2013-04-04. PMID:23302448. |
less than half of patients with schizophrenia obtain full response to antipsychotic drugs and, while clozapine represents the treatment of choice for refractory psychosis, a significant number of individuals remain only partially responsive. |
2013-04-04 |
2023-08-12 |
Not clear |
| Avril Pereira, Betty Zhang, Peter Malcolm, Suresh Sundra. Clozapine regulation of p90RSK and c-Fos signaling via the ErbB1-ERK pathway is distinct from olanzapine and haloperidol in mouse cortex and striatum. Progress in neuro-psychopharmacology & biological psychiatry. vol 40. 2013-03-26. PMID:23142770. |
the unique spatio-temporal expression of downstream nuclear markers of the erbb1-erk pathway invoked by clozapine may contribute to its effectiveness in treatment resistant schizophrenia. |
2013-03-26 |
2023-08-12 |
mouse |
| Gary Remington, Ofer Agid, George Foussias, Margaret Hahn, Naren Rao, Mark Sinyo. Clozapine's role in the treatment of first-episode schizophrenia. The American journal of psychiatry. vol 170. issue 2. 2013-03-25. PMID:23377634. |
clozapine's role in the treatment of first-episode schizophrenia. |
2013-03-25 |
2023-08-12 |
Not clear |