| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Handan Gunduz-Bruce, Stephen Oliver, Ralitza Gueorguieva, Kimberlee Forselius-Bielen, Deepak C D'Souza, Zoran Zimolo, Cenk Tek, Styliani Kaliora, Susan Ray, Georgios Petride. Efficacy of pimozide augmentation for clozapine partial responders with schizophrenia. Schizophrenia research. vol 143. issue 2-3. 2013-07-02. PMID:23219861. |
efficacy of pimozide augmentation for clozapine partial responders with schizophrenia. |
2013-07-02 |
2023-08-12 |
Not clear |
| Handan Gunduz-Bruce, Stephen Oliver, Ralitza Gueorguieva, Kimberlee Forselius-Bielen, Deepak C D'Souza, Zoran Zimolo, Cenk Tek, Styliani Kaliora, Susan Ray, Georgios Petride. Efficacy of pimozide augmentation for clozapine partial responders with schizophrenia. Schizophrenia research. vol 143. issue 2-3. 2013-07-02. PMID:23219861. |
a substantial number of patients with treatment-resistant schizophrenia respond only partially to clozapine. |
2013-07-02 |
2023-08-12 |
Not clear |
| Handan Gunduz-Bruce, Stephen Oliver, Ralitza Gueorguieva, Kimberlee Forselius-Bielen, Deepak C D'Souza, Zoran Zimolo, Cenk Tek, Styliani Kaliora, Susan Ray, Georgios Petride. Efficacy of pimozide augmentation for clozapine partial responders with schizophrenia. Schizophrenia research. vol 143. issue 2-3. 2013-07-02. PMID:23219861. |
we have conducted a randomized double-blind placebo controlled clinical trial in patients with schizophrenia currently receiving clozapine with partial response, and tested the efficacy of pimozide augmentation on positive and negative symptoms and also on neurocognitive measures. |
2013-07-02 |
2023-08-12 |
Not clear |
| b' Sefa Vay\\xc4\\xb1so\\xc4\\x9flu, A Elif An\\xc4\\xb1l Ya\\xc4\\x9fc\\xc4\\xb1o\\xc4\\x9flu, S\\xc3\\xbcha Ya\\xc4\\x9fc\\xc4\\xb1o\\xc4\\x9flu, Sevilay Karahan, O\\xc4\\x9fuzhan Karc\\xc4\\xb1, S Can G\\xc3\\xbcrel, M K\\xc3\\xa2z\\xc4\\xb1m Yaz\\xc4\\xb1c\\xc4\\xb. Lamotrigine augmentation in patients with schizophrenia who show partial response to clozapine treatment. Schizophrenia research. vol 143. issue 1. 2013-07-01. PMID:23217729.' |
lamotrigine augmentation in patients with schizophrenia who show partial response to clozapine treatment. |
2013-07-01 |
2023-08-12 |
Not clear |
| b' Sefa Vay\\xc4\\xb1so\\xc4\\x9flu, A Elif An\\xc4\\xb1l Ya\\xc4\\x9fc\\xc4\\xb1o\\xc4\\x9flu, S\\xc3\\xbcha Ya\\xc4\\x9fc\\xc4\\xb1o\\xc4\\x9flu, Sevilay Karahan, O\\xc4\\x9fuzhan Karc\\xc4\\xb1, S Can G\\xc3\\xbcrel, M K\\xc3\\xa2z\\xc4\\xb1m Yaz\\xc4\\xb1c\\xc4\\xb. Lamotrigine augmentation in patients with schizophrenia who show partial response to clozapine treatment. Schizophrenia research. vol 143. issue 1. 2013-07-01. PMID:23217729.' |
several placebo controlled studies investigating lamotrigine augmentation of clozapine in schizophrenia patients with partial response have shown varying results. |
2013-07-01 |
2023-08-12 |
Not clear |
| Juliano S Souza, Monica Kayo, Ivson Tassell, Camila Bertini Martins, Helio Elki. Efficacy of olanzapine in comparison with clozapine for treatment-resistant schizophrenia: evidence from a systematic review and meta-analyses. CNS spectrums. vol 18. issue 2. 2013-06-26. PMID:23253621. |
efficacy of olanzapine in comparison with clozapine for treatment-resistant schizophrenia: evidence from a systematic review and meta-analyses. |
2013-06-26 |
2023-08-12 |
Not clear |
| Juliano S Souza, Monica Kayo, Ivson Tassell, Camila Bertini Martins, Helio Elki. Efficacy of olanzapine in comparison with clozapine for treatment-resistant schizophrenia: evidence from a systematic review and meta-analyses. CNS spectrums. vol 18. issue 2. 2013-06-26. PMID:23253621. |
clozapine is considered the gold standard for the treatment of patients with treatment-resistant schizophrenia (trs); however, randomized controlled trials (rct) of olanzapine showed efficacy similar to clozapine in patients with trs. |
2013-06-26 |
2023-08-12 |
Not clear |
| Ney C do Carmo Borges, Rafael B Astigarraga, Carlos E Sverdloff, Paulo R Galvinas, Bruno C Borges, Ronilson A Moren. Comparative bioavailability of two oral formulations of clozapine in steady state administered in schizophrenic volunteers under individualized dose regime. Current clinical pharmacology. vol 7. issue 4. 2013-06-18. PMID:22794154. |
this method agrees with the requirements proposed by the us food and drug administration of high sensitivity, specificity and high sample throughput and was used to evaluate the pharmacokinetic profiles and bioequivalence of the two clozapine formulations in twenty six schizophrenic patients affected by refractory schizophrenia under steady-state conditions. |
2013-06-18 |
2023-08-12 |
human |
| S Ozcan, A Soydan, L Tama. Supersensitivity psychosis in a case with clozapine tolerance. European review for medical and pharmacological sciences. vol 16 Suppl 4. 2013-06-12. PMID:23090814. |
despite its serious side effects, clozapine is still the golden standard in treatment of schizophrenia due to its effectiveness and lack of extrapyramidal side effects. |
2013-06-12 |
2023-08-12 |
Not clear |
| Feras Ali Mustaf. Schizophrenia past clozapine: what works? Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277242. |
schizophrenia past clozapine: what works? |
2013-06-12 |
2023-08-12 |
Not clear |
| Feras Ali Mustaf. Schizophrenia past clozapine: what works? Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277242. |
clozapine is superior to other antipsychotic drugs for treatment of refractory schizophrenia. |
2013-06-12 |
2023-08-12 |
Not clear |
| Arun K Tiwari, Eva J Brandl, Caroline Weber, Olga Likhodi, Clement C Zai, Margaret K Hahn, Jeffrey A Lieberman, Herbert Y Meltzer, James L Kennedy, Daniel J Mülle. Association of a functional polymorphism in neuropeptide Y with antipsychotic-induced weight gain in schizophrenia patients. Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277265. |
because npy is a potent orexigenic peptide stimulating food intake, and genetic variation of the gene has been shown to influence development of obesity, we investigated the impact of npy polymorphisms on antipsychotic-induced bwg.we analyzed 5 polymorphisms in the npy gene (rs10551063, rs16147, rs5573, rs5574, and rs16475) in schizophrenia subjects (n = 226), treated mostly with clozapine and olanzapine for up to 14 weeks. |
2013-06-12 |
2023-08-12 |
human |
| Jong-Hoon Kim, Sang Hoon Yi, Jinyoung Lee, Yong Sik Ki. Effects of clozapine on heart rate dynamics and their relationship with therapeutic response in treatment-resistant schizophrenia. Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277266. |
effects of clozapine on heart rate dynamics and their relationship with therapeutic response in treatment-resistant schizophrenia. |
2013-06-12 |
2023-08-12 |
Not clear |
| Jong-Hoon Kim, Sang Hoon Yi, Jinyoung Lee, Yong Sik Ki. Effects of clozapine on heart rate dynamics and their relationship with therapeutic response in treatment-resistant schizophrenia. Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277266. |
the purpose of the present study was to investigate the effects of clozapine on the nonlinear complexity measures of hrv in patients with treatment-resistant schizophrenia to find novel electrophysiological markers that indicate response to clozapine treatment. |
2013-06-12 |
2023-08-12 |
Not clear |
| Jong-Hoon Kim, Sang Hoon Yi, Jinyoung Lee, Yong Sik Ki. Effects of clozapine on heart rate dynamics and their relationship with therapeutic response in treatment-resistant schizophrenia. Journal of clinical psychopharmacology. vol 33. issue 1. 2013-06-12. PMID:23277266. |
forty patients with treatment-resistant schizophrenia were evaluated during 8 weeks of clozapine monotherapy. |
2013-06-12 |
2023-08-12 |
Not clear |
| Peiyan Wong, Cecilia Chin Roei Chang, Christine E Marx, Marc G Caron, William C Wetsel, Xiaodong Zhan. Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice. PloS one. vol 7. issue 12. 2013-05-30. PMID:23240026. |
it has been shown that the level of pregnenolone is altered in certain brain areas of schizophrenic patients, and clozapine enhances pregnenolone in the cns in rats, suggesting that pregnenolone could be used to treat certain symptoms of schizophrenia. |
2013-05-30 |
2023-08-12 |
mouse |
| Anto P Rajkumar, Balasubramanian Poonkuzhali, Anju Kuruvilla, Molly Jacob, Kuruthukulangara S Jaco. Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. International clinical psychopharmacology. vol 28. issue 1. 2013-05-21. PMID:23104241. |
clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. |
2013-05-21 |
2023-08-12 |
Not clear |
| Anto P Rajkumar, Balasubramanian Poonkuzhali, Anju Kuruvilla, Molly Jacob, Kuruthukulangara S Jaco. Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. International clinical psychopharmacology. vol 28. issue 1. 2013-05-21. PMID:23104241. |
fixed oral doses of clozapine produce up to 45-fold interindividual variability among its serum levels in patients with treatment-resistant schizophrenia. |
2013-05-21 |
2023-08-12 |
Not clear |
| Anto P Rajkumar, Balasubramanian Poonkuzhali, Anju Kuruvilla, Molly Jacob, Kuruthukulangara S Jaco. Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. International clinical psychopharmacology. vol 28. issue 1. 2013-05-21. PMID:23104241. |
we assessed the sociodemographic and clinical profiles, cognition, disability and psychopathology of 101 consecutive patients with treatment-resistant schizophrenia on a stable dose of clozapine, using standard assessment schedules. |
2013-05-21 |
2023-08-12 |
Not clear |
| Ruiling Zhang, Wei Hao, Miao Pan, Chuansheng Wang, Xiuli Zhang, Da Chun Chen, Mei Hong Xiu, Fu De Yang, Thomas R Kosten, Xiang Yang Zhan. The prevalence and clinical-demographic correlates of diabetes mellitus in chronic schizophrenic patients receiving clozapine. Human psychopharmacology. vol 26. issue 6. 2013-05-17. PMID:21826737. |
to examine the prevalence and correlates of diabetes in a large sample of chinese patients with schizophrenia on long-term clozapine treatment, because this population previously has received little systematic study. |
2013-05-17 |
2023-08-12 |
Not clear |