| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ketil Arne Espnes, Kent Ove Heimdal, Olav Spigse. A puzzling case of increased serum clozapine levels in a patient with inflammation and infection. Therapeutic drug monitoring. vol 34. issue 5. 2013-05-14. PMID:22929408. |
a 23-year old male with a history of schizophrenia treated with clozapine 900 mg/d was admitted to the hospital for a gastrointestinal infection. |
2013-05-14 |
2023-08-12 |
Not clear |
| Ya-Wen Lai, Che-Yi Chou, Winston W Shen, Mong-Liang L. Pityriasis rosea-like eruption associated with clozapine: a case report. General hospital psychiatry. vol 34. issue 6. 2013-05-03. PMID:22516218. |
clozapine, a complex neurotransmitter receptor-binding in antipsychotic agent, is usually used for treatment-resistant schizophrenia. |
2013-05-03 |
2023-08-12 |
Not clear |
| Ya-Wen Lai, Che-Yi Chou, Winston W Shen, Mong-Liang L. Pityriasis rosea-like eruption associated with clozapine: a case report. General hospital psychiatry. vol 34. issue 6. 2013-05-03. PMID:22516218. |
we report a 54-year-old male patient with chronic schizophrenia who had received clozapine for 28 days and developed generalized skin rashes, high fever, and elevated values in liver function tests. |
2013-05-03 |
2023-08-12 |
Not clear |
| Jimmi Nielsen, John M Kane, Christoph U Correl. Real-world effectiveness of clozapine in patients with bipolar disorder: results from a 2-year mirror-image study. Bipolar disorders. vol 14. issue 8. 2013-05-03. PMID:23107278. |
clozapine remains the drug of choice for treatment-resistant schizophrenia but the evidence for its use in severe bipolar disorder (bd) remains sparse. |
2013-05-03 |
2023-08-12 |
Not clear |
| A P Rajkumar, B Poonkuzhali, A Kuruvilla, A Srivastava, M Jacob, K S Jaco. Outcome definitions and clinical predictors influence pharmacogenetic associations between HTR3A gene polymorphisms and response to clozapine in patients with schizophrenia. Psychopharmacology. vol 224. issue 3. 2013-04-29. PMID:22700043. |
outcome definitions and clinical predictors influence pharmacogenetic associations between htr3a gene polymorphisms and response to clozapine in patients with schizophrenia. |
2013-04-29 |
2023-08-12 |
Not clear |
| Oliver D Howes, Francis Vergunst, Siobhan Gee, Philip McGuire, Shitij Kapur, David Taylo. Adherence to treatment guidelines in clinical practice: study of antipsychotic treatment prior to clozapine initiation. The British journal of psychiatry : the journal of mental science. vol 201. issue 6. 2013-04-29. PMID:22955007. |
clozapine is the only antipsychotic drug licensed for treatment-resistant schizophrenia but its use is often delayed. |
2013-04-29 |
2023-08-12 |
Not clear |
| Michele Hill, Oliver Freudenreic. Clozapine: key discussion points for prescribers. Clinical schizophrenia & related psychoses. vol 6. issue 4. 2013-04-04. PMID:23302447. |
clozapine is the most effective antipsychotic medication for treatment-refractory schizophrenia and is also approved for suicidality in schizophrenia patients. |
2013-04-04 |
2023-08-12 |
Not clear |
| Margaret K Hahn, Tony Cohn, Celine Teo, Gary Remingto. Topiramate in schizophrenia: a review of effects on psychopathology and metabolic parameters. Clinical schizophrenia & related psychoses. vol 6. issue 4. 2013-04-04. PMID:23302448. |
less than half of patients with schizophrenia obtain full response to antipsychotic drugs and, while clozapine represents the treatment of choice for refractory psychosis, a significant number of individuals remain only partially responsive. |
2013-04-04 |
2023-08-12 |
Not clear |
| Avril Pereira, Betty Zhang, Peter Malcolm, Suresh Sundra. Clozapine regulation of p90RSK and c-Fos signaling via the ErbB1-ERK pathway is distinct from olanzapine and haloperidol in mouse cortex and striatum. Progress in neuro-psychopharmacology & biological psychiatry. vol 40. 2013-03-26. PMID:23142770. |
the unique spatio-temporal expression of downstream nuclear markers of the erbb1-erk pathway invoked by clozapine may contribute to its effectiveness in treatment resistant schizophrenia. |
2013-03-26 |
2023-08-12 |
mouse |
| Gary Remington, Ofer Agid, George Foussias, Margaret Hahn, Naren Rao, Mark Sinyo. Clozapine's role in the treatment of first-episode schizophrenia. The American journal of psychiatry. vol 170. issue 2. 2013-03-25. PMID:23377634. |
clozapine's role in the treatment of first-episode schizophrenia. |
2013-03-25 |
2023-08-12 |
Not clear |
| Gary Remington, Ofer Agid, George Foussias, Margaret Hahn, Naren Rao, Mark Sinyo. Clozapine's role in the treatment of first-episode schizophrenia. The American journal of psychiatry. vol 170. issue 2. 2013-03-25. PMID:23377634. |
in contrast, the notable reduction in response rate to second-line treatments, coupled with clozapine's substantial response rate in refractory schizophrenia and evidence indicating better outcomes with early, effective treatment, makes a compelling argument for research examining clinical and functional outcomes with clozapine positioned as a second-line treatment. |
2013-03-25 |
2023-08-12 |
Not clear |
| Jimmi Nielsen, Rasmus Røge, Ole Schjerning, Holger J Sørensen, David Taylo. Geographical and temporal variations in clozapine prescription for schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 22. issue 11. 2013-03-18. PMID:22503785. |
geographical and temporal variations in clozapine prescription for schizophrenia. |
2013-03-18 |
2023-08-12 |
Not clear |
| Jimmi Nielsen, Rasmus Røge, Ole Schjerning, Holger J Sørensen, David Taylo. Geographical and temporal variations in clozapine prescription for schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 22. issue 11. 2013-03-18. PMID:22503785. |
trends in the prescription of clozapine in patients with icd-10 f20.x schizophrenia were assessed using data from danish national registers. |
2013-03-18 |
2023-08-12 |
Not clear |
| Jimmi Nielsen, Rasmus Røge, Ole Schjerning, Holger J Sørensen, David Taylo. Geographical and temporal variations in clozapine prescription for schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 22. issue 11. 2013-03-18. PMID:22503785. |
three substudies were carried out: (i) an assessment of differences in national prescription patterns between 1996 and 2007 using a cross-sectional design; (ii) a comparison of time from first schizophrenia diagnosis to first prescription of clozapine in a five-year cohort study, using the cox regression model, of two patient groups who were first diagnosed in 1996 and in 2003; (iii) an assessment of differences in the general psychiatric hospitals' use of clozapine in 2009. |
2013-03-18 |
2023-08-12 |
Not clear |
| Jimmi Nielsen, Rasmus Røge, Ole Schjerning, Holger J Sørensen, David Taylo. Geographical and temporal variations in clozapine prescription for schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 22. issue 11. 2013-03-18. PMID:22503785. |
the results are as follows: (i) the percentage of schizophrenia patients receiving clozapine rose from 9.0% in 1996 to 10.1% in 2007 (p<0.001). |
2013-03-18 |
2023-08-12 |
Not clear |
| Jimmi Nielsen, Rasmus Røge, Ole Schjerning, Holger J Sørensen, David Taylo. Geographical and temporal variations in clozapine prescription for schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 22. issue 11. 2013-03-18. PMID:22503785. |
(ii) time from diagnosis with schizophrenia until first clozapine prescription was longer for patients diagnosed in 2003 compared to those diagnosed in 1996 (hr: 0.28 ci: 0.16-0.49). |
2013-03-18 |
2023-08-12 |
Not clear |
| Jimmi Nielsen, Rasmus Røge, Ole Schjerning, Holger J Sørensen, David Taylo. Geographical and temporal variations in clozapine prescription for schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 22. issue 11. 2013-03-18. PMID:22503785. |
although, the percentage of schizophrenia patients receiving clozapine increased from 1996 to 2007, the time from diagnosis of schizophrenia until first prescription of clozapine increased. |
2013-03-18 |
2023-08-12 |
Not clear |
| Tian-Mei Si, Yun-Shu Zhang, Liang Shu, Ke-Qing Li, Xie-He Liu, Qi-Yi Mei, Gao-Hua Wang, Pei-Shen Bai, Li-Ping Ji, Xian-Sheng Cheng, Cui Ma, Jian-Guo Shi, Hong-Yan Zhang, Hong Ma, Xin Y. Use of clozapine for the treatment of schizophrenia: findings of the 2006 research on the china psychotropic prescription studies. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 10. issue 2. 2013-02-25. PMID:23430459. |
use of clozapine for the treatment of schizophrenia: findings of the 2006 research on the china psychotropic prescription studies. |
2013-02-25 |
2023-08-12 |
Not clear |
| b' Kazuhiro Tajima-Pozo, Diana Zambrano-Enriquez, Laura de Anta, Mar\\xc3\\xada Dolores Moron, Jose Luis Carrasco, Juan Jos\\xc3\\xa9 Lopez-Ibor, Marina Diaz-Mars\\xc3\\xa. Practicing exorcism in schizophrenia. BMJ case reports. vol 2011. 2013-02-19. PMID:22707465.' |
we report the case of a 28-year-old patient who had been diagnosed 5 years previously with paranoid schizophrenia (treated with clozapine, risperidone, ziprasidone and onlanzapine without a complete response) and was also receiving treatment in a first episode psychosis unit in spain. |
2013-02-19 |
2023-08-12 |
Not clear |
| Albertine A Scheltema Beduin, Marije Swets, Marise Machielsen, Nikie Korve. Obsessive-compulsive symptoms in patients with schizophrenia: a naturalistic cross-sectional study comparing treatment with clozapine, olanzapine, risperidone, and no antipsychotics in 543 patients. The Journal of clinical psychiatry. vol 73. issue 11. 2013-02-19. PMID:23218156. |
obsessive-compulsive symptoms in patients with schizophrenia: a naturalistic cross-sectional study comparing treatment with clozapine, olanzapine, risperidone, and no antipsychotics in 543 patients. |
2013-02-19 |
2023-08-12 |
Not clear |