| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yeon-Jin Kim, Seung-Ho No, Sang-Yeol Le. Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 11. issue 3. 2014-01-27. PMID:24465255. |
clozapine remains the treatment of choice in refractory schizophrenia despite its various requirement to prescribe, such as mandatory blood monitoring program and various metabolic complication. |
2014-01-27 |
2023-08-12 |
Not clear |
| Yeon-Jin Kim, Seung-Ho No, Sang-Yeol Le. Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 11. issue 3. 2014-01-27. PMID:24465255. |
we report a case of a successful early clozapine trial in the treatment of first-episode schizophrenia patient, considering poor treatment response and repeated self-injurious behavior. |
2014-01-27 |
2023-08-12 |
Not clear |
| Yeon-Jin Kim, Seung-Ho No, Sang-Yeol Le. Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 11. issue 3. 2014-01-27. PMID:24465255. |
this case highlights the efficacy of an early clozapine trial as a second-line treatment for first-episode schizophrenia in contrast to switching or combination treatment strategy. |
2014-01-27 |
2023-08-12 |
Not clear |
| Alexandre Pons i Villanueva, Anna Romero, Javier Goti, Emilio Fernandez-Egea, Juan Undurraga, Xavier Carne, Miquel Bernard. Should obesity be a limiting factor for clozapine treatment? Revista de psiquiatria y salud mental. vol 6. issue 2. 2014-01-23. PMID:23084801. |
clozapine is the first choice in drug-resistant schizophrenia but also causes important weight changes. |
2014-01-23 |
2023-08-12 |
Not clear |
| Ramamoorthy Rajkumar, Sana Suri, Hong Min Deng, Gavin Stewart Daw. Nicotine and clozapine cross-prime the locus coeruleus noradrenergic system to induce long-lasting potentiation in the rat hippocampus. Hippocampus. vol 23. issue 7. 2014-01-23. PMID:23520012. |
interactions between nicotine and clozapine are of interest because of the prevalence of smoking in patients with schizophrenia and increasing interest in the use of nicotinic receptor ligands as cognitive enhancers. |
2014-01-23 |
2023-08-12 |
rat |
| b' Pavo Filakovi\\xc4\\x87, Anamarija Petek Eri\\xc4\\x8. Pharmacotherapy of suicidal behaviour in major depression, schizophrenia and bipolar disorder. Collegium antropologicum. vol 37. issue 3. 2014-01-16. PMID:24308257.' |
confirmed drug with anti-suicidal effect, clozapine, is not first choice medication and does not represent general solution for suicidality in schizophrenia. |
2014-01-16 |
2023-08-12 |
Not clear |
| M L Hamshere, J T R Walters, R Smith, A L Richards, E Green, D Grozeva, I Jones, L Forty, L Jones, K Gordon-Smith, B Riley, F A O'Neill, T O'Neill, K S Kendler, P Sklar, S Purcell, J Kranz, D Morris, M Gill, P Holmans, N Craddock, A Corvin, M J Owen, M C O'Donova. Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:22614287. |
we tested 78 of the 81 snps in 2640 individuals with a clinical diagnosis of schizophrenia attending a clozapine clinic (clozuk), 2504 cases with a research diagnosis of bipolar disorder, and 2878 controls. |
2014-01-03 |
2023-08-12 |
Not clear |
| Jaran Eriksen, Staffan Rosenbor. [No given alternatives to clozapine in treatment-resistant schizophrenia]. Lakartidningen. vol 110. issue 41. 2013-12-05. PMID:24187896. |
[no given alternatives to clozapine in treatment-resistant schizophrenia]. |
2013-12-05 |
2023-08-12 |
Not clear |
| Ignacio Vera, Livia Rezende, Vicente Molina, Javier Sanz-Fuentenebr. Clozapine as treatment of first choice in first psychotic episodes. What do we know? Actas espanolas de psiquiatria. vol 40. issue 5. 2013-12-02. PMID:23076611. |
clozapine has become a keystone in the treatment of psychosis, with multiple contributions to the treatment of schizophrenia. |
2013-12-02 |
2023-08-12 |
Not clear |
| Cody J Wenthur, Craig W Lindsle. Classics in chemical neuroscience: clozapine. ACS chemical neuroscience. vol 4. issue 7. 2013-11-25. PMID:24047509. |
clozapine was the first true breakthrough in schizophrenia treatment since the discovery of chlorpromazine in 1950, effectively treating positive, negative, and some cognitive symptoms, as well as possessing unprecedented efficacy in treatment-resistant patients. |
2013-11-25 |
2023-08-12 |
Not clear |
| Anirban Ray, Santanu Munsh. Augmenting amisulpride with clozapine had led to unmasking of akathisia. Industrial psychiatry journal. vol 21. issue 2. 2013-11-19. PMID:24250050. |
amisulpride is a newer antipsychotic, which is very effective on its own, as well as augmenting other antipsychotic clozapine, which is an effective molecule for treatment resistant schizophrenia. |
2013-11-19 |
2023-08-12 |
Not clear |
| Li-jun Li, De-wei Shang, Wen-biao Li, Wei Guo, Xi-pei Wang, Yu-peng Ren, An-ning Li, Pei-xin Fu, Shuang-min Ji, Wei Lu, Chuan-yue Wan. Population pharmacokinetics of clozapine and its primary metabolite norclozapine in Chinese patients with schizophrenia. Acta pharmacologica Sinica. vol 33. issue 11. 2013-11-07. PMID:22820910. |
population pharmacokinetics of clozapine and its primary metabolite norclozapine in chinese patients with schizophrenia. |
2013-11-07 |
2023-08-12 |
Not clear |
| Li-jun Li, De-wei Shang, Wen-biao Li, Wei Guo, Xi-pei Wang, Yu-peng Ren, An-ning Li, Pei-xin Fu, Shuang-min Ji, Wei Lu, Chuan-yue Wan. Population pharmacokinetics of clozapine and its primary metabolite norclozapine in Chinese patients with schizophrenia. Acta pharmacologica Sinica. vol 33. issue 11. 2013-11-07. PMID:22820910. |
to develop a combined population pharmacokinetic model (ppk) to assess the magnitude and variability of exposure to both clozapine and its primary metabolite norclozapine in chinese patients with refractory schizophrenia via sparse sampling with a focus on the effects of covariates on the pharmacokinetic parameters. |
2013-11-07 |
2023-08-12 |
Not clear |
| Kazeem Olaide Adebayo, Nurudeen Ibrahim, Temilola Mosanya, Benjamin Eegunranti, Babatunde Suleiman, Akeem Ayankunl. Life-threatening haematemesis associated with clozapine: a case report and literature review. Therapeutic advances in psychopharmacology. vol 3. issue 5. 2013-10-29. PMID:24167703. |
the patient was a 46-year-old male being managed for chronic schizophrenia with treatment resistance who developed sudden severe haematemesis following commencement of clozapine for 6 weeks. |
2013-10-29 |
2023-08-12 |
Not clear |
| Gursharan Lal Kashyap, Jitendra Nayar, Adnan Bashier, Soosamma Varghes. Treatment of clozapine-induced priapism by goserline acetate injection. Therapeutic advances in psychopharmacology. vol 3. issue 5. 2013-10-29. PMID:24167706. |
clozapine (denzapine) is a treatment for resistant schizophrenia. |
2013-10-29 |
2023-08-12 |
Not clear |
| Chian-Jue Kuo, Shu-Yu Yang, Ya-Tang Liao, Wei J Chen, Wen-Chung Lee, Wen-Yi Shau, Yao-Tung Chang, Shang-Ying Tsai, Chiao-Chicy Che. Second-generation antipsychotic medications and risk of pneumonia in schizophrenia. Schizophrenia bulletin. vol 39. issue 3. 2013-10-28. PMID:22282455. |
clinicians who prescribe clozapine to patients with schizophrenia should closely monitor them for pneumonia, particularly at the start of therapy and when clozapine is combined with other antipsychotics. |
2013-10-28 |
2023-08-12 |
Not clear |
| Taro Kishi, Kiyoshi Fujita, Osamu Furukawa, Tatsuyo Suzuki, Masatsugu Moriwaki, Mari Nitta, Miho Hattori, Tomoko Tsunoka, Raja Chekuri, John M Kane, Christoph U Correll, Nakao Iwat. Efficacy and tolerability of clozapine in Japanese patients with treatment-resistant schizophrenia: results from a 12-week, flexible dose study using raters masked to antipsychotic choice. Asian journal of psychiatry. vol 6. issue 3. 2013-10-17. PMID:23642976. |
efficacy and tolerability of clozapine in japanese patients with treatment-resistant schizophrenia: results from a 12-week, flexible dose study using raters masked to antipsychotic choice. |
2013-10-17 |
2023-08-12 |
Not clear |
| Taro Kishi, Kiyoshi Fujita, Osamu Furukawa, Tatsuyo Suzuki, Masatsugu Moriwaki, Mari Nitta, Miho Hattori, Tomoko Tsunoka, Raja Chekuri, John M Kane, Christoph U Correll, Nakao Iwat. Efficacy and tolerability of clozapine in Japanese patients with treatment-resistant schizophrenia: results from a 12-week, flexible dose study using raters masked to antipsychotic choice. Asian journal of psychiatry. vol 6. issue 3. 2013-10-17. PMID:23642976. |
japan approved clozapine for treatment-resistant schizophrenia in june 2009. |
2013-10-17 |
2023-08-12 |
Not clear |
| Taro Kishi, Kiyoshi Fujita, Osamu Furukawa, Tatsuyo Suzuki, Masatsugu Moriwaki, Mari Nitta, Miho Hattori, Tomoko Tsunoka, Raja Chekuri, John M Kane, Christoph U Correll, Nakao Iwat. Efficacy and tolerability of clozapine in Japanese patients with treatment-resistant schizophrenia: results from a 12-week, flexible dose study using raters masked to antipsychotic choice. Asian journal of psychiatry. vol 6. issue 3. 2013-10-17. PMID:23642976. |
a twelve-week, single-arm clinical trial of clozapine in treatment-resistant schizophrenia inpatients, was conducted under real-world conditions using raters masked for type of antipsychotic. |
2013-10-17 |
2023-08-12 |
Not clear |
| Taro Kishi, Kiyoshi Fujita, Osamu Furukawa, Tatsuyo Suzuki, Masatsugu Moriwaki, Mari Nitta, Miho Hattori, Tomoko Tsunoka, Raja Chekuri, John M Kane, Christoph U Correll, Nakao Iwat. Efficacy and tolerability of clozapine in Japanese patients with treatment-resistant schizophrenia: results from a 12-week, flexible dose study using raters masked to antipsychotic choice. Asian journal of psychiatry. vol 6. issue 3. 2013-10-17. PMID:23642976. |
these findings suggest that clozapine is beneficial in japanese treatment-resistant schizophrenia patients. |
2013-10-17 |
2023-08-12 |
Not clear |