Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ofer Agid, Laura Schulze, Tamara Arenovich, Gautam Sajeev, Krysta McDonald, George Foussias, Gagan Fervaha, Gary Remingto. Antipsychotic response in first-episode schizophrenia: efficacy of high doses and switching. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 9. 2014-05-01. PMID:23706529. |
data were gathered from a treatment algorithm implemented in patients with first-episode schizophrenia that employs two antipsychotic trials at increasing doses before clozapine. |
2014-05-01 |
2023-08-12 |
human |
Andreia W P Hazewinkel, Jan P A M Bogers, Erik J Gilta. Add-on filgrastim during clozapine rechallenge unsuccessful in preventing agranulocytosis. General hospital psychiatry. vol 35. issue 5. 2014-04-25. PMID:23395419. |
we describe a patient with schizophrenia who developed agranulocytosis during treatment with clozapine and who did not respond to other antipsychotics. |
2014-04-25 |
2023-08-12 |
Not clear |
Fabiana Barzotti Kohlrausch, Clarissa Severino-Gama, Maria Inês Lobato, Paulo Belmonte-de-Abreu, Angel Carracedo, Mara Helena Hut. The CYP1A2 -163C>A polymorphism is associated with clozapine-induced generalized tonic-clonic seizures in Brazilian schizophrenia patients. Psychiatry research. vol 209. issue 2. 2014-04-02. PMID:23601795. |
we evaluated two polymorphisms at cyp1a2 (*1c and *1f) in a sample of 108 european-derived patients with schizophrenia and their influence on the pro-convulsive effect of clozapine. |
2014-04-02 |
2023-08-12 |
Not clear |
Adam Wysokiński, Iwona Kłoszewsk. Homocysteine levels in patients with schizophrenia on clozapine monotherapy. Neurochemical research. vol 38. issue 10. 2014-03-28. PMID:23873378. |
homocysteine levels in patients with schizophrenia on clozapine monotherapy. |
2014-03-28 |
2023-08-12 |
human |
Adam Wysokiński, Iwona Kłoszewsk. Homocysteine levels in patients with schizophrenia on clozapine monotherapy. Neurochemical research. vol 38. issue 10. 2014-03-28. PMID:23873378. |
data for 24 subjects with schizophrenia treated with clozapine and 24 age- and sex-matched healthy volunteers was analyzed. |
2014-03-28 |
2023-08-12 |
human |
Amy E Austin, Saskia S Guddat, Michael Tsokos, John D Gilbert, Roger W Byar. Multiple injuries in suicide simulating homicide: report of three cases. Journal of forensic and legal medicine. vol 20. issue 6. 2014-03-26. PMID:23910842. |
a high level of clozapine was detected on toxicological analysis of blood and a history of schizophrenia was reported. |
2014-03-26 |
2023-08-12 |
Not clear |
Jessica L Gören, Mark Meterko, Sandra Williams, Gary J Young, Errol Baker, Chia-Hung Chou, Amy M Kilbourne, Mark S Baue. Antipsychotic prescribing pathways, polypharmacy, and clozapine use in treatment of schizophrenia. Psychiatric services (Washington, D.C.). vol 64. issue 6. 2014-03-24. PMID:23450334. |
antipsychotic prescribing pathways, polypharmacy, and clozapine use in treatment of schizophrenia. |
2014-03-24 |
2023-08-12 |
Not clear |
Pau Celada, Analía Bortolozzi, Francesc Artiga. Serotonin 5-HT1A receptors as targets for agents to treat psychiatric disorders: rationale and current status of research. CNS drugs. vol 27. issue 9. 2014-03-19. PMID:23757185. |
postsynaptic 5-ht1a-rs in the prefrontal cortex (pfc) also appear important for the superior clinical effects of clozapine and other second-generation (atypical) antipsychotic drugs in the treatment of schizophrenia and related psychotic disorders. |
2014-03-19 |
2023-08-12 |
mouse |
Pau Celada, Analía Bortolozzi, Francesc Artiga. Serotonin 5-HT1A receptors as targets for agents to treat psychiatric disorders: rationale and current status of research. CNS drugs. vol 27. issue 9. 2014-03-19. PMID:23757185. |
the stimulation of 5-ht1a-rs in the pfc leads to the distal activation of the mesocortical pathway and to an increased dopamine release in pfc, an effect likely involved in the clinical actions of clozapine in negative symptoms and cognitive deficits in schizophrenia. |
2014-03-19 |
2023-08-12 |
mouse |
Tetsuro Enomoto, Toshihiko Ito, Keisuke Sekine, Reiko Yasui, Yuko Ashizawa, Yoriyasu Uju, Tatsuro Hayakawa, Kazumi Tsukad. [Clinical experience with clozapine in 55 cases of treatment-resistant schizophrenia]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 115. issue 9. 2014-03-19. PMID:24228473. |
[clinical experience with clozapine in 55 cases of treatment-resistant schizophrenia]. |
2014-03-19 |
2023-08-12 |
Not clear |
Tetsuro Enomoto, Toshihiko Ito, Keisuke Sekine, Reiko Yasui, Yuko Ashizawa, Yoriyasu Uju, Tatsuro Hayakawa, Kazumi Tsukad. [Clinical experience with clozapine in 55 cases of treatment-resistant schizophrenia]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 115. issue 9. 2014-03-19. PMID:24228473. |
up until october 2012, kohnodai hospital had introduced clozapine treatment for 55 cases of treatment-resistant schizophrenia. |
2014-03-19 |
2023-08-12 |
Not clear |
Karen E Stevens, Lijun Zheng, Daniel J Abram. Intermittent versus continuous central administration of clozapine in DBA/2 mice, improvement in sensory inhibition deficits. Schizophrenia research. vol 149. issue 1-3. 2014-03-11. PMID:23863771. |
systemic administration of clozapine, the most efficacious antipsychotic medication, improves sensory inhibition deficits in both schizophrenia patients and dba/2 mice. |
2014-03-11 |
2023-08-12 |
mouse |
Javier Sanz-Fuentenebro, Diana Taboada, Tomás Palomo, María Aragües, Santiago Ovejero, Cristina Del Alamo, Vicente Molin. Randomized trial of clozapine vs. risperidone in treatment-naïve first-episode schizophrenia: results after one year. Schizophrenia research. vol 149. issue 1-3. 2014-03-11. PMID:23870807. |
randomized trial of clozapine vs. risperidone in treatment-naïve first-episode schizophrenia: results after one year. |
2014-03-11 |
2023-08-12 |
Not clear |
Javier Sanz-Fuentenebro, Diana Taboada, Tomás Palomo, María Aragües, Santiago Ovejero, Cristina Del Alamo, Vicente Molin. Randomized trial of clozapine vs. risperidone in treatment-naïve first-episode schizophrenia: results after one year. Schizophrenia research. vol 149. issue 1-3. 2014-03-11. PMID:23870807. |
our research group is developing a non-commercial, multicentric and open label study on the differential efficacy between clozapine and risperidone in first-episode schizophrenia. |
2014-03-11 |
2023-08-12 |
Not clear |
Venkata Kolli, Kevin Denton, Dileep Borra, Madhuri Pulluri, Ashish Sharm. Treating chemotherapy induced agranulocytosis with granulocyte colony-stimulating factors in a patient on clozapine. Psycho-oncology. vol 22. issue 7. 2014-03-05. PMID:23059755. |
clozapine is reserved for overcoming treatment resistance in schizophrenia. |
2014-03-05 |
2023-08-12 |
Not clear |
Venkata Kolli, Kevin Denton, Dileep Borra, Madhuri Pulluri, Ashish Sharm. Treating chemotherapy induced agranulocytosis with granulocyte colony-stimulating factors in a patient on clozapine. Psycho-oncology. vol 22. issue 7. 2014-03-05. PMID:23059755. |
malignancy is common in schizophrenia; however, there is limited evidence available on continuing clozapine with chemotherapy, with both having hematological adverse effects. |
2014-03-05 |
2023-08-12 |
Not clear |
T A Munshi, D Volochniouk, T Hassan, N Mazha. Clozapine-induced myocarditis: is mandatory monitoring warranted for its early recognition? Case reports in psychiatry. vol 2014. 2014-03-03. PMID:24587933. |
clozapine is an atypical antipsychotic used for treatment resistant schizophrenia. |
2014-03-03 |
2023-08-12 |
Not clear |
Hellme Najim, David Heath, Pranveer Sing. Antipsychotic prescribing before clozapine in a community psychiatric hospital: a case note review. Psychiatria Danubina. vol 25 Suppl 2. 2014-02-25. PMID:23995168. |
to examine whether prescribing clozapine was delayed in treatment resistant schizophrenia (trs), and elucidate possible reasons for this. |
2014-02-25 |
2023-08-12 |
Not clear |
Helena Korosec Jagodic, Mark Agius, Peter Pregel. Psychopharmacotherapy prescription and suicidal behaviour. Psychiatria Danubina. vol 25 Suppl 2. 2014-02-25. PMID:23995201. |
finally, studies on antipsychotic prescription demonstrated that particularly treatment with clozapine decreased suicide mortality among individuals with schizophrenia and schizoaffective disorders and on the other hand lithium reduced suicide rate among individuals with mood disorders. |
2014-02-25 |
2023-08-12 |
Not clear |
G Huguet, A Lillo-Le Louet, L Darnige, H Loo, M O Kreb. [Clozapine rechallenge in resistant schizophrenia disorder affecting "super sensitive" patients, after neutropenia under clozapine: a case report]. L'Encephale. vol 39 Suppl 1. 2014-02-24. PMID:23557674. |
[clozapine rechallenge in resistant schizophrenia disorder affecting "super sensitive" patients, after neutropenia under clozapine: a case report]. |
2014-02-24 |
2023-08-12 |
Not clear |