Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Nina R Schooler, Stephen R Marder, K N R Chengappa, Georgios Petrides, Donna Ames, William C Wirshing, Marjorie McMeniman, Robert W Baker, Haranath Parepally, Daniel Umbricht, John M Kan. Clozapine and risperidone in moderately refractory schizophrenia: a 6-month randomized double-blind comparison. The Journal of clinical psychiatry. vol 77. issue 5. 2017-06-07. PMID:27035871. |
clozapine and risperidone in moderately refractory schizophrenia: a 6-month randomized double-blind comparison. |
2017-06-07 |
2023-08-13 |
Not clear |
Nina R Schooler, Stephen R Marder, K N R Chengappa, Georgios Petrides, Donna Ames, William C Wirshing, Marjorie McMeniman, Robert W Baker, Haranath Parepally, Daniel Umbricht, John M Kan. Clozapine and risperidone in moderately refractory schizophrenia: a 6-month randomized double-blind comparison. The Journal of clinical psychiatry. vol 77. issue 5. 2017-06-07. PMID:27035871. |
clozapine remains the only medication indicated for refractory schizophrenia. |
2017-06-07 |
2023-08-13 |
Not clear |
Oddur Ingimarsson, James H MacCabe, Magnús Haraldsson, Halldóra Jónsdóttir, Engilbert Sigurdsso. Neutropenia and agranulocytosis during treatment of schizophrenia with clozapine versus other antipsychotics: an observational study in Iceland. BMC psychiatry. vol 16. issue 1. 2017-06-05. PMID:27955666. |
neutropenia and agranulocytosis during treatment of schizophrenia with clozapine versus other antipsychotics: an observational study in iceland. |
2017-06-05 |
2023-08-13 |
Not clear |
Oddur Ingimarsson, James H MacCabe, Magnús Haraldsson, Halldóra Jónsdóttir, Engilbert Sigurdsso. Neutropenia and agranulocytosis during treatment of schizophrenia with clozapine versus other antipsychotics: an observational study in Iceland. BMC psychiatry. vol 16. issue 1. 2017-06-05. PMID:27955666. |
however, in iceland where clozapine monitoring is less stringent allows an observational study to be done on the risk of agranulocytosis and neutropenia during treatment with clozapine compared with other antipsychotics among patients with schizophrenia. |
2017-06-05 |
2023-08-13 |
Not clear |
Chittaranjan Andrad. Antipsychotic Drugs in Schizophrenia: Relative Effects in Patients With and Without Treatment Resistance. The Journal of clinical psychiatry. vol 77. issue 12. 2017-06-05. PMID:28086018. |
at the risk of oversimplification, it appears that clozapine retains its preeminence in medication-refractory schizophrenia and that clozapine and olanzapine are both associated with superior efficacy outcomes in non-refractory patients. |
2017-06-05 |
2023-08-13 |
human |
S Schreiter, A Hasan, T Majic, A Wullschleger, M Schouler-Ocak, F Bermpohl, S Gutwinsk. [Obsessive-Compulsive Symptoms in a Sample of Patients with Chronic Schizophrenia Under Clozapine Treatment]. Fortschritte der Neurologie-Psychiatrie. vol 84. issue 11. 2017-05-30. PMID:27846652. |
[obsessive-compulsive symptoms in a sample of patients with chronic schizophrenia under clozapine treatment]. |
2017-05-30 |
2023-08-13 |
Not clear |
Maurizio Pompili, Ross J Baldessarini, Alberto Forte, Denise Erbuto, Gianluca Serafini, Andrea Fiorillo, Mario Amore, Paolo Girard. Do Atypical Antipsychotics Have Antisuicidal Effects? A Hypothesis-Generating Overview. International journal of molecular sciences. vol 17. issue 10. 2017-05-12. PMID:27727180. |
clozapine remains the only treatment with an fda-recognized indication for reducing suicidal risk (in schizophrenia). |
2017-05-12 |
2023-08-13 |
Not clear |
Helio Elkis, Peter F Buckle. Treatment-Resistant Schizophrenia. The Psychiatric clinics of North America. vol 39. issue 2. 2017-05-01. PMID:27216902. |
although treatment-resistant schizophrenia (trs) was described 50 years ago and has a gold standard treatment with clozapine based on well-defined criteria, there is still a matter of great interest and controversy. |
2017-05-01 |
2023-08-13 |
Not clear |
Hirofumi Hirakawa, Takeshi Terao, Toshiko Tanaka, Hiroaki Sato, Reiji Yoshimur. A Case of Mutism in Noncatatonic Schizophrenia Responding to Small Dose of Fluvoxamine Addition to Clozapine. Journal of clinical psychopharmacology. vol 36. issue 5. 2017-04-28. PMID:27508430. |
a case of mutism in noncatatonic schizophrenia responding to small dose of fluvoxamine addition to clozapine. |
2017-04-28 |
2023-08-13 |
Not clear |
Rebecca N S Harrison, Robin M Murray, Sang Hyuck Lee, Jose Paya Cano, David Dempster, Charles J Curtis, Danai Dima, Fiona Gaughran, Gerome Breen, Simone de Jon. Gene-expression analysis of clozapine treatment in whole blood of patients with psychosis. Psychiatric genetics. vol 26. issue 5. 2017-04-25. PMID:27315048. |
clozapine is an atypical antipsychotic primarily prescribed for treatment-resistant schizophrenia. |
2017-04-25 |
2023-08-13 |
Not clear |
Charilaos Gerasimou, Georgia Phaedra Vitali, George D Vavougios, Charalabos Papageorgiou, Athanasios Douzenis, Styliani I Kokoris, Ioannis Liappas, Emmanouil Rizo. Clozapine Associated with Autoimmune Reaction, Fever and Low Level Cardiotoxicity - A Case Report. In vivo (Athens, Greece). vol 31. issue 1. 2017-04-25. PMID:28064233. |
clozapine is a second-generation antipsychotic drug used in treatment-resistant schizophrenia. |
2017-04-25 |
2023-08-13 |
Not clear |
Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Shinya Watanabe, Hidehiro Umehara, Shinji Shimodera, Takanobu Nakazawa, Masataka Kikuchi, Akihiro Nakaya, Hitoshi Hashimoto, Issei Imoto, Ryota Hashimoto, Tetsuro Ohmor. Effect of Clozapine on DNA Methylation in Peripheral Leukocytes from Patients with Treatment-Resistant Schizophrenia. International journal of molecular sciences. vol 18. issue 3. 2017-04-20. PMID:28335437. |
effect of clozapine on dna methylation in peripheral leukocytes from patients with treatment-resistant schizophrenia. |
2017-04-20 |
2023-08-13 |
Not clear |
Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Shinya Watanabe, Hidehiro Umehara, Shinji Shimodera, Takanobu Nakazawa, Masataka Kikuchi, Akihiro Nakaya, Hitoshi Hashimoto, Issei Imoto, Ryota Hashimoto, Tetsuro Ohmor. Effect of Clozapine on DNA Methylation in Peripheral Leukocytes from Patients with Treatment-Resistant Schizophrenia. International journal of molecular sciences. vol 18. issue 3. 2017-04-20. PMID:28335437. |
clozapine is an atypical antipsychotic, that is established as the treatment of choice for treatment-resistant schizophrenia (scz). |
2017-04-20 |
2023-08-13 |
Not clear |
Hong-Qiang Sun, Su-Xia Li, Fang-Bin Chen, Yan Zhang, Peng Li, Mei Jin, Yan Sun, Fan Wang, Wei-Feng Mi, Le Shi, Jing-Li Yue, Fu-De Yang, Lin L. Diurnal neurobiological alterations after exposure to clozapine in first-episode schizophrenia patients. Psychoneuroendocrinology. vol 64. 2017-04-18. PMID:26630391. |
diurnal neurobiological alterations after exposure to clozapine in first-episode schizophrenia patients. |
2017-04-18 |
2023-08-13 |
Not clear |
Dan-Dan Tian, Wei Wang, Hua-Ning Wang, Stephen Cho Wing Sze, Zhang-Jin Zhan. Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats. Molecules (Basel, Switzerland). vol 21. issue 6. 2017-04-18. PMID:27240333. |
radix rehmanniae, fructus schisandrae, radix bupleuri, and fructus gardeniae are often used alongside with clozapine (clz) for schizophrenia patients in order to reduce side effects and enhance therapeutic efficacy. |
2017-04-18 |
2023-08-13 |
rat |
Julia E H Brown, Gisela Mezquida, Emilio Fernandez-Ege. Well-being in clozapine-treated schizophrenia patients: The significance of positive symptoms. Comprehensive psychiatry. vol 68. 2017-04-12. PMID:27234195. |
this cross-sectional study sought to explore potential clinical factors that may predict subjective well-being scores in chronic schizophrenia patients (n=142) receiving clozapine treatment. |
2017-04-12 |
2023-08-13 |
Not clear |
Jari-Pekka Klemettilä, Olli Kampman, Niko Seppälä, Merja Viikki, Mari Hämäläinen, Eeva Moilanen, Esa Leinone. Resistin as an inflammatory marker in patients with schizophrenia treated with clozapine. Nordic journal of psychiatry. vol 71. issue 2. 2017-03-29. PMID:27658459. |
resistin as an inflammatory marker in patients with schizophrenia treated with clozapine. |
2017-03-29 |
2023-08-13 |
Not clear |
Aysun Kalenderoğlu, Mustafa Çeli. [Augmentation of Clozapine With Paliperidone in Schizophrenia Patients With Partial Response to Treatment: A Case Series]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 27. issue 1. 2017-03-27. PMID:27369686. |
[augmentation of clozapine with paliperidone in schizophrenia patients with partial response to treatment: a case series]. |
2017-03-27 |
2023-08-13 |
Not clear |
Aysun Kalenderoğlu, Mustafa Çeli. [Augmentation of Clozapine With Paliperidone in Schizophrenia Patients With Partial Response to Treatment: A Case Series]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 27. issue 1. 2017-03-27. PMID:27369686. |
clozapine is the only antipsychotic which has definitely shown to be effective in refractory schizophrenia. |
2017-03-27 |
2023-08-13 |
Not clear |
Aysun Kalenderoğlu, Mustafa Çeli. [Augmentation of Clozapine With Paliperidone in Schizophrenia Patients With Partial Response to Treatment: A Case Series]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 27. issue 1. 2017-03-27. PMID:27369686. |
clozapine treatment is usually preferred in schizophrenia patients with a partial response to treatment and augmentation strategies are tried when clozapine also fails to provide full treatment response. |
2017-03-27 |
2023-08-13 |
Not clear |