Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Danielle L Taylor, Arun K Tiwari, Jeffrey A Lieberman, Steven G Potkin, Herbert Y Meltzer, Jo Knight, Gary Remington, Daniel J Müller, James L Kenned. Genetic association analysis of N-methyl-D-aspartate receptor subunit gene GRIN2B and clinical response to clozapine. Human psychopharmacology. vol 31. issue 2. 2016-12-13. PMID:26876050. |
clozapine is the most efficacious drug for treatment-resistant schizophrenia and may deliver superior therapeutic effects partly by modulating glutamate neurotransmission. |
2016-12-13 |
2023-08-13 |
Not clear |
Jimmi Nielsen, Corina Young, Petru Ifteni, Taishiro Kishimoto, Yu-Tao Xiang, Peter F J Schulte, Christoph U Correll, David Taylo. Worldwide Differences in Regulations of Clozapine Use. CNS drugs. vol 30. issue 2. 2016-12-13. PMID:26884144. |
clozapine remains the drug of choice for treatment-resistant schizophrenia. |
2016-12-13 |
2023-08-13 |
Not clear |
Mark Olfson, Tobias Gerhard, Stephen Crystal, T Scott Strou. Clozapine for Schizophrenia: State Variation in Evidence-Based Practice. Psychiatric services (Washington, D.C.). vol 67. issue 2. 2016-11-01. PMID:26522679. |
clozapine for schizophrenia: state variation in evidence-based practice. |
2016-11-01 |
2023-08-13 |
Not clear |
Jimmy Lee, Hiroyoshi Takeuchi, Gagan Fervaha, Gwen Li Sin, George Foussias, Ofer Agid, Saeed Farooq, Gary Remingto. Subtyping Schizophrenia by Treatment Response: Antipsychotic Development and the Central Role of Positive Symptoms. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 60. issue 11. 2016-10-05. PMID:26720509. |
evidence suggests that aps, both old and new, are comparable in terms of efficacy; however, one ap, clozapine, is uniquely effective in one subgroup of patients (that is, those with treatment-resistant schizophrenia [trs]). |
2016-10-05 |
2023-08-13 |
Not clear |
Jimmy Lee, Hiroyoshi Takeuchi, Gagan Fervaha, Gwen Li Sin, George Foussias, Ofer Agid, Saeed Farooq, Gary Remingto. Subtyping Schizophrenia by Treatment Response: Antipsychotic Development and the Central Role of Positive Symptoms. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 60. issue 11. 2016-10-05. PMID:26720509. |
this permits us to subdivide schizophrenia into 3 specific groups: ap responsive, clozapine responsive, and clozapine resistant. |
2016-10-05 |
2023-08-13 |
Not clear |
Eric Huang, Malgorzata Maciukiewicz, Clement C Zai, Arun K Tiwari, Jiang Li, Steven G Potkin, Jeffrey A Lieberman, Herbert Y Meltzer, Daniel J Müller, James L Kenned. Preliminary evidence for association of genome-wide significant DRD2 schizophrenia risk variant with clozapine response. Pharmacogenomics. vol 17. issue 2. 2016-09-15. PMID:26666695. |
preliminary evidence for association of genome-wide significant drd2 schizophrenia risk variant with clozapine response. |
2016-09-15 |
2023-08-13 |
Not clear |
Narjes Hendouei, Seyed Hamzeh Hosseini, Amin Panahi, Zahra Khazaeipour, Fatemeh Barari, Adeleh Sahebnasagh, Shahram Al. Negative Correlation between Serum S100B and Leptin Levels in Schizophrenic Patients During Treatment with Clozapine and Risperidone: Preliminary Evidence. Iranian journal of pharmaceutical research : IJPR. vol 15. issue 1. 2016-09-09. PMID:27610173. |
in this study we evaluated the relationship between s100b and leptin in schizophrenic patients under treatment with clozapine and risperidone.this study included 19 patients meeting the dsm-iv-tr criteria for schizophrenia, having body mass index (bmi) of 16- 25 kg/m(2) and suffering schizophrenia for more than 3 years and from this study. |
2016-09-09 |
2023-08-13 |
Not clear |
Sefa Vayısoğlu, Elif Anıl Yağcıoğl. [Augmentation strategies in patients with schizophrenia who show partial response to clozapine treatment]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 25. issue 3. 2016-09-06. PMID:25219694. |
[augmentation strategies in patients with schizophrenia who show partial response to clozapine treatment]. |
2016-09-06 |
2023-08-13 |
Not clear |
Sefa Vayısoğlu, Elif Anıl Yağcıoğl. [Augmentation strategies in patients with schizophrenia who show partial response to clozapine treatment]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 25. issue 3. 2016-09-06. PMID:25219694. |
a significant proportion of patients with schizophrenia receiving clozapine remain with partial response. |
2016-09-06 |
2023-08-13 |
Not clear |
Sefa Vayısoğlu, Elif Anıl Yağcıoğl. [Augmentation strategies in patients with schizophrenia who show partial response to clozapine treatment]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 25. issue 3. 2016-09-06. PMID:25219694. |
the number of controlled studies evaluating augmentation of clozapine in schizophrenia patients are highest for risperidone and lamotrigine add on treatments. |
2016-09-06 |
2023-08-13 |
Not clear |
Kathleen M Patchan, Charles Richardson, Gopal Vyas, Deanna L Kell. The risk of suicide after clozapine discontinuation: Cause for concern. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 27. issue 4. 2016-09-06. PMID:26554366. |
clozapine is a second-generation antipsychotic that has been shown to reduce suicidal ideation and suicidal behaviors in patients with schizophrenia. |
2016-09-06 |
2023-08-13 |
Not clear |
Jagath Pushpakumara, Piyumanthi Karunarathna, Sivagamaroobasunthari Sivathiran, Ajantha Liyanage, Jegarajah Indrakuma. Clozapine induced pancytopenia leading to severe sepsis: an unusual early complication. BMC research notes. vol 8. 2016-09-06. PMID:26674072. |
clozapine is a second generation antipsychotic used to treat resistant schizophrenia and other psychotic illnesses. |
2016-09-06 |
2023-08-13 |
Not clear |
Pichai Ittasakul, Anthony Archer, Jennifer Kezman, Wanlop Atsariyasing, Morris B Goldma. Rapid Rechallenge with Clozapine Following Pronounced Myocarditis in a Treatment-Resistant Schizophrenia Patient. Clinical schizophrenia & related psychoses. vol 10. issue 2. 2016-09-01. PMID:27440213. |
rapid rechallenge with clozapine following pronounced myocarditis in a treatment-resistant schizophrenia patient. |
2016-09-01 |
2023-08-13 |
Not clear |
John M Kane, Christoph U Correl. The Role of Clozapine in Treatment-Resistant Schizophrenia. JAMA psychiatry. vol 73. issue 3. 2016-08-22. PMID:26841681. |
the role of clozapine in treatment-resistant schizophrenia. |
2016-08-22 |
2023-08-13 |
Not clear |
John Lally, Mary J Docherty, James H MacCab. Pharmacological interventions for clozapine-induced sinus tachycardia. The Cochrane database of systematic reviews. issue 6. 2016-08-17. PMID:27277334. |
clozapine is an efficacious treatment for treatment-resistant schizophrenia; however its use can be limited by side effect intolerability. |
2016-08-17 |
2023-08-13 |
Not clear |
Stephen M Stah. Clozapine: is now the time for more clinicians to adopt this orphan? CNS spectrums. vol 19. issue 4. 2016-08-08. PMID:25267329. |
although many patients with schizophrenia fail to respond adequately to trials of 2 or more antipsychotics, utilization of clozapine for these patients remains low, despite recommendations for its use by accepted treatment guidelines. |
2016-08-08 |
2023-08-13 |
Not clear |
Chien-Yu Chen, Hsien-Yuan Lane, Chieh-Hsin Li. Effects of Antipsychotics on Bone Mineral Density in Patients with Schizophrenia: Gender Differences. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 14. issue 3. 2016-08-04. PMID:27489377. |
our previous study has demonstrated that clozapine which is among the ps antipsychotics is beneficial for bmd when compared with pr antipsychotics in women with chronic schizophrenia. |
2016-08-04 |
2023-08-13 |
Not clear |
Ippei Takeuchi, Manako Hanya, Junji Uno, Yuhei Amano, Keiko Fukai, Kiyoshi Fujita, Hiroyuki Kame. A Questionnaire-based Study of the Views of Schizophrenia Patients and Psychiatric Healthcare Professionals in Japan about the Side Effects of Clozapine. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 14. issue 3. 2016-08-04. PMID:27489383. |
a questionnaire-based study of the views of schizophrenia patients and psychiatric healthcare professionals in japan about the side effects of clozapine. |
2016-08-04 |
2023-08-13 |
Not clear |
Ippei Takeuchi, Manako Hanya, Junji Uno, Yuhei Amano, Keiko Fukai, Kiyoshi Fujita, Hiroyuki Kame. A Questionnaire-based Study of the Views of Schizophrenia Patients and Psychiatric Healthcare Professionals in Japan about the Side Effects of Clozapine. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 14. issue 3. 2016-08-04. PMID:27489383. |
the aim of this study was to assess current practice related to the side effects of clozapine in clozapine-treated patients with schizophrenia and psychiatric healthcare professionals in japan. |
2016-08-04 |
2023-08-13 |
Not clear |
Charles H Earnshaw, Lucy Powell, Owen Haene. Lessons Learned and Questions Raised by an Atypical Case of Clozapine-Induced Myocarditis. Case reports in psychiatry. vol 2016. 2016-08-01. PMID:27478671. |
a caucasian male in his early twenties suffering from treatment resistant schizophrenia was started on clozapine. |
2016-08-01 |
2023-08-13 |
Not clear |