| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicholas Meyer, Siobhan Gee, Eromona Whiskey, David Taylor, Aleksandar Mijovic, Fiona Gaughran, Sukhi Shergill, James H MacCab. Optimizing outcomes in clozapine rechallenge following neutropenia: a cohort analysis. The Journal of clinical psychiatry. vol 76. issue 11. 2016-03-29. PMID:26646037. |
certain patients with treatment-refractory schizophrenia may be rechallenged with clozapine following previous neutropenia. |
2016-03-29 |
2023-08-13 |
Not clear |
| Hara Tsekou, Elias Angelopoulos, Thomas Paparrigopoulos, Spyretta Golemati, Constantin R Soldatos, George N Papadimitriou, Periklis Y Ktona. Sleep EEG and spindle characteristics after combination treatment with clozapine in drug-resistant schizophrenia: a pilot study. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. vol 32. issue 2. 2016-03-28. PMID:25350635. |
sleep eeg and spindle characteristics after combination treatment with clozapine in drug-resistant schizophrenia: a pilot study. |
2016-03-28 |
2023-08-13 |
Not clear |
| Hara Tsekou, Elias Angelopoulos, Thomas Paparrigopoulos, Spyretta Golemati, Constantin R Soldatos, George N Papadimitriou, Periklis Y Ktona. Sleep EEG and spindle characteristics after combination treatment with clozapine in drug-resistant schizophrenia: a pilot study. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. vol 32. issue 2. 2016-03-28. PMID:25350635. |
clozapine is an atypical neuroleptic agent, effective in treating drug-resistant schizophrenia. |
2016-03-28 |
2023-08-13 |
Not clear |
| Hara Tsekou, Elias Angelopoulos, Thomas Paparrigopoulos, Spyretta Golemati, Constantin R Soldatos, George N Papadimitriou, Periklis Y Ktona. Sleep EEG and spindle characteristics after combination treatment with clozapine in drug-resistant schizophrenia: a pilot study. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. vol 32. issue 2. 2016-03-28. PMID:25350635. |
the aim of this work was to investigate overall sleep architecture and sleep spindle morphology characteristics, before and after combination treatment with clozapine, in patients with drug-resistant schizophrenia who underwent polysomnography. |
2016-03-28 |
2023-08-13 |
Not clear |
| Shinichiro Nakajima, Hiroyoshi Takeuchi, Eric Plitman, Gagan Fervaha, Philip Gerretsen, Fernando Caravaggio, Jun Ku Chung, Yusuke Iwata, Gary Remington, Ariel Graff-Guerrer. Neuroimaging findings in treatment-resistant schizophrenia: A systematic review: Lack of neuroimaging correlates of treatment-resistant schizophrenia. Schizophrenia research. vol 164. issue 1-3. 2016-03-28. PMID:25684554. |
however, neuroimaging correlates of treatment-resistant schizophrenia (trs) and superior effects of clozapine on trs remain unclear. |
2016-03-28 |
2023-08-13 |
Not clear |
| Allen E Thornton, Ric M Procyshyn, Alasdair M Barr, G William MacEwan, William G Hone. Cognition and Plasma Ratio of Clozapine to N-desmethylclozapine in Patients With Clozapine-Resistant Schizophrenia. The American journal of psychiatry. vol 172. issue 12. 2016-03-22. PMID:26619773. |
cognition and plasma ratio of clozapine to n-desmethylclozapine in patients with clozapine-resistant schizophrenia. |
2016-03-22 |
2023-08-13 |
Not clear |
| M T Abou-Sale. Psychopharmacology of substance misuse and comorbid psychiatric disorders. Acta neuropsychiatrica. vol 16. issue 1. 2016-03-18. PMID:26983873. |
further studies of the biology of comorbidity will impact the use of effective pharmaceuticals such as clozapine with dual effects on schizophrenia and substance misuse. |
2016-03-18 |
2023-08-13 |
Not clear |
| M Wardenier, C J Slooff, J Arend. Efficacy of risperidone, olanzapine and clozapine in the treatment of therapy resistant schizophrenia. Acta neuropsychiatrica. vol 12. issue 4. 2016-03-16. PMID:26975433. |
efficacy of risperidone, olanzapine and clozapine in the treatment of therapy resistant schizophrenia. |
2016-03-16 |
2023-08-13 |
Not clear |
| Seiya Miyamoto, Lars Fredrik Jarskog, W Wolfgang Fleischhacke. Schizophrenia: when clozapine fails. Current opinion in psychiatry. vol 28. issue 3. 2016-03-15. PMID:25768082. |
schizophrenia: when clozapine fails. |
2016-03-15 |
2023-08-13 |
Not clear |
| Seiya Miyamoto, Lars Fredrik Jarskog, W Wolfgang Fleischhacke. Schizophrenia: when clozapine fails. Current opinion in psychiatry. vol 28. issue 3. 2016-03-15. PMID:25768082. |
this article reviews the recent evidence for therapeutic strategies for patients with treatment-resistant schizophrenia (trs) not responding to or only partially responding to clozapine. |
2016-03-15 |
2023-08-13 |
Not clear |
| R S Kah. New dopaminergic and non-dopaminergic theories in schizophrenia and their therapeutic impact. Acta neuropsychiatrica. vol 9. issue 2. 2016-03-14. PMID:26972129. |
the finding that clozapine (leponex®), clinically superior to conventional neuroleptics, is a weak da2 antagonist but a potent 5-ht1c and 5-ht2 antagonist has further stimulated 5-ht-related research in schizophrenia. |
2016-03-14 |
2023-08-13 |
Not clear |
| J A Boer, H G Westenberg, J W Louwerens, C J Sloof. The clinical significance of atypical antipsychotics. Acta neuropsychiatrica. vol 3. issue 4. 2016-03-10. PMID:26956202. |
in addition to the treatment of acute schizophrenia, these compounds might be of use in the treatment of treatment resistent schizophrenia (clozapine), tardive dyskinesia and psychosis during the course of parkinson's disease. |
2016-03-10 |
2023-08-13 |
Not clear |
| J-P Klemettilä, O Kampman, N Seppälä, M Viikki, M Hämäläinen, E Moilanen, N Mononen, T Lehtimäki, E Leinone. Association study of the HTR2C, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia. European psychiatry : the journal of the Association of European Psychiatrists. vol 30. issue 2. 2016-03-09. PMID:25284335. |
association study of the htr2c, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia. |
2016-03-09 |
2023-08-13 |
Not clear |
| J-P Klemettilä, O Kampman, N Seppälä, M Viikki, M Hämäläinen, E Moilanen, N Mononen, T Lehtimäki, E Leinone. Association study of the HTR2C, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia. European psychiatry : the journal of the Association of European Psychiatrists. vol 30. issue 2. 2016-03-09. PMID:25284335. |
clozapine treatment is associated with weight gain and cardio-metabolic consequences among patients with schizophrenia. |
2016-03-09 |
2023-08-13 |
Not clear |
| J-P Klemettilä, O Kampman, N Seppälä, M Viikki, M Hämäläinen, E Moilanen, N Mononen, T Lehtimäki, E Leinone. Association study of the HTR2C, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia. European psychiatry : the journal of the Association of European Psychiatrists. vol 30. issue 2. 2016-03-09. PMID:25284335. |
the aim of the present study was first to test for a possible role of serum leptin and adiponectin levels as a marker of weight gain in association with inflammatory cytokines/adipokines (il-6, il-1ra, hs-crp and adipsin), and second to study associations between snps lep rs7799039 (-2548 a/g), adipoq rs1501299 and htr2c rs1414334 and weight gain and levels of leptin and adiponectin, in 190 patients with schizophrenia on clozapine treatment, with retrospectively assessed weight change and cross-sectionally measured cytokine levels. |
2016-03-09 |
2023-08-13 |
Not clear |
| J-P Klemettilä, O Kampman, N Seppälä, M Viikki, M Hämäläinen, E Moilanen, N Mononen, T Lehtimäki, E Leinone. Association study of the HTR2C, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia. European psychiatry : the journal of the Association of European Psychiatrists. vol 30. issue 2. 2016-03-09. PMID:25284335. |
the results of the present study do not support a major role of snps lep rs7799039, adipoq rs1501299 and htr2c rs1414334 in the regulation of weight gain or association of serum levels of leptin and adiponectin and corresponding studied snps in patients with schizophrenia on clozapine treatment. |
2016-03-09 |
2023-08-13 |
Not clear |
| Anto P Rajkumar, B Poonkuzhali, Anju Kuruvilla, Alok Srivastava, Molly Jacob, K S Jaco. Association between CYP1A2 gene single nucleotide polymorphisms and clinical responses to clozapine in patients with treatment-resistant schizophrenia. Acta neuropsychiatrica. vol 25. issue 1. 2016-03-09. PMID:26953068. |
association between cyp1a2 gene single nucleotide polymorphisms and clinical responses to clozapine in patients with treatment-resistant schizophrenia. |
2016-03-09 |
2023-08-13 |
Not clear |
| Anto P Rajkumar, B Poonkuzhali, Anju Kuruvilla, Alok Srivastava, Molly Jacob, K S Jaco. Association between CYP1A2 gene single nucleotide polymorphisms and clinical responses to clozapine in patients with treatment-resistant schizophrenia. Acta neuropsychiatrica. vol 25. issue 1. 2016-03-09. PMID:26953068. |
despite clozapine's superior clinical efficacy in treatment-resistant schizophrenia (trs), its adverse effects, need for periodic leukocyte monitoring, cost and variable clinical outcomes mandate a clinical need to predict its treatment response. |
2016-03-09 |
2023-08-13 |
Not clear |
| Manit Srisurapanont, Sirijit Suttajit, Narong Maneeton, Benchalak Maneeto. Efficacy and safety of aripiprazole augmentation of clozapine in schizophrenia: a systematic review and meta-analysis of randomized-controlled trials. Journal of psychiatric research. vol 62. 2016-03-02. PMID:25619176. |
efficacy and safety of aripiprazole augmentation of clozapine in schizophrenia: a systematic review and meta-analysis of randomized-controlled trials. |
2016-03-02 |
2023-08-13 |
Not clear |
| Manit Srisurapanont, Sirijit Suttajit, Narong Maneeton, Benchalak Maneeto. Efficacy and safety of aripiprazole augmentation of clozapine in schizophrenia: a systematic review and meta-analysis of randomized-controlled trials. Journal of psychiatric research. vol 62. 2016-03-02. PMID:25619176. |
limited options are available for clozapine-resistant schizophrenia and intolerable side effects of clozapine. |
2016-03-02 |
2023-08-13 |
Not clear |