| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Valerie M Anderson, Meghan E McIlwain, Robert R Kydd, Bruce R Russel. Does cognitive impairment in treatment-resistant and ultra-treatment-resistant schizophrenia differ from that in treatment responders? Psychiatry research. vol 230. issue 3. 2016-07-26. PMID:26564550. |
fifty-one patients with schizophrenia were assigned to one of three groups dependent on their clinical history: (i) 16 people who had responded well to first-line antipsychotic medication, (ii) 20 people who were treatment-resistant but responding to clozapine monotherapy, (iii) 15 people who were ultra-treatment-resistant/clozapine-resistant but responding to antipsychotic polypharmacy. |
2016-07-26 |
2023-08-13 |
human |
| James E Hotham, Patrick J D Simpson, Rosalie S Brooman-White, Amlan Basu, Callum C Ross, Sharon A Humphreys, Fintan Larkin, Nitin Gupta, Mrigendra Da. Augmentation of clozapine with amisulpride: an effective therapeutic strategy for violent treatment-resistant schizophrenia patients in a UK high-security hospital. CNS spectrums. vol 19. issue 5. 2016-07-21. PMID:24284256. |
augmentation of clozapine with amisulpride: an effective therapeutic strategy for violent treatment-resistant schizophrenia patients in a uk high-security hospital. |
2016-07-21 |
2023-08-12 |
Not clear |
| James E Hotham, Patrick J D Simpson, Rosalie S Brooman-White, Amlan Basu, Callum C Ross, Sharon A Humphreys, Fintan Larkin, Nitin Gupta, Mrigendra Da. Augmentation of clozapine with amisulpride: an effective therapeutic strategy for violent treatment-resistant schizophrenia patients in a UK high-security hospital. CNS spectrums. vol 19. issue 5. 2016-07-21. PMID:24284256. |
clozapine is used in the management of treatment-resistant schizophrenia and is effective in reducing aggression; however a subgroup of patients is poorly responsive. |
2016-07-21 |
2023-08-12 |
Not clear |
| James E Hotham, Patrick J D Simpson, Rosalie S Brooman-White, Amlan Basu, Callum C Ross, Sharon A Humphreys, Fintan Larkin, Nitin Gupta, Mrigendra Da. Augmentation of clozapine with amisulpride: an effective therapeutic strategy for violent treatment-resistant schizophrenia patients in a UK high-security hospital. CNS spectrums. vol 19. issue 5. 2016-07-21. PMID:24284256. |
here we present a case series of 6 schizophrenia patients, within a high-security hospital, who have a history of serious violence and who were treated with clozapine augmented with amisulpride. |
2016-07-21 |
2023-08-12 |
Not clear |
| Darcy Brown, Fintan Larkin, Samrat Sengupta, Jose L Romero-Ureclay, Callum C Ross, Nitin Gupta, Morris Vinestock, Mrigendra Da. Clozapine: an effective treatment for seriously violent and psychopathic men with antisocial personality disorder in a UK high-security hospital. CNS spectrums. vol 19. issue 5. 2016-07-21. PMID:24698103. |
a number of studies have demonstrated the anti-aggressive properties of clozapine in schizophrenia and its positive effect in borderline personality disorder. |
2016-07-21 |
2023-08-13 |
Not clear |
| William G Honer, Andrea A Jones, Allen E Thornton, Alasdair M Barr, Ric M Procyshyn, Fidel Vila-Rodrigue. Response trajectories to clozapine in a secondary analysis of pivotal trials support using treatment response to subtype schizophrenia. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 60. issue 3 Suppl 2. 2016-07-20. PMID:25886676. |
response trajectories to clozapine in a secondary analysis of pivotal trials support using treatment response to subtype schizophrenia. |
2016-07-20 |
2023-08-13 |
Not clear |
| G Piriu, E Torac, L E Gaman, L Iosif, I C Tivig, C Delia, M Gilca, I Stoian, V Atanasi. Clozapine and risperidone influence on cortisol and estradiol levels in male patients with schizophrenia. Journal of medicine and life. vol 8. issue 4. 2016-07-18. PMID:26664488. |
clozapine and risperidone influence on cortisol and estradiol levels in male patients with schizophrenia. |
2016-07-18 |
2023-08-13 |
human |
| G Piriu, E Torac, L E Gaman, L Iosif, I C Tivig, C Delia, M Gilca, I Stoian, V Atanasi. Clozapine and risperidone influence on cortisol and estradiol levels in male patients with schizophrenia. Journal of medicine and life. vol 8. issue 4. 2016-07-18. PMID:26664488. |
we have investigated the effects of clozapine and risperidone on estradiol levels in men with schizophrenia. |
2016-07-18 |
2023-08-13 |
human |
| G Piriu, E Torac, L E Gaman, L Iosif, I C Tivig, C Delia, M Gilca, I Stoian, V Atanasi. Clozapine and risperidone influence on cortisol and estradiol levels in male patients with schizophrenia. Journal of medicine and life. vol 8. issue 4. 2016-07-18. PMID:26664488. |
our study found decreased estradiol levels in men with schizophrenia treated with clozapine and risperidone, while prolactin levels were increased only in the risperidone treated group. |
2016-07-18 |
2023-08-13 |
human |
| b' Francesco Bartoli, Cristina Crocamo, Massimo Clerici, Giuseppe Carr\\xc3\\xa. Second-generation antipsychotics and adiponectin levels in schizophrenia: A comparative meta-analysis. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26164075.' |
eight studies were included with data suitable for carrying out four different comparisons: clozapine vs. olanzapine (including n=877 individuals with schizophrenia); clozapine vs. risperidone (n=660); olanzapine vs. risperidone (n=738); quetiapine vs. risperidone (n=186). |
2016-07-12 |
2023-08-13 |
human |
| Benjamin Sneider, Sofie Gry Pristed, Christoph U Correll, Jimmi Nielse. Frequency and correlates of antipsychotic polypharmacy among patients with schizophrenia in Denmark: A nation-wide pharmacoepidemiological study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26256007. |
independent correlates of app, explaining 37.9% of the variance, included a higher number of patients per psychiatrist (or=1.04/10 patients, ci=1.03-1.06, p<0.001),lower proportion of males (or=0.80, ci=0.74-0.86), younger age (or=1.00, ci=0.99-1.00), several schizophrenia subtypes (paranoid: or=1.24, ci=1.11-1.38,hebephrenic: or=1.30, ci=1.03-1.63, other: or=1.95 ci=1.17-3.24, unspecified: or=1.21 ci=1.05-1.40), living alone (or=1.12, ci=1.01-1.24), being institutionalized (or=1.23, ci=1.06-1.42), receiving early retirement pension (or=1.21, ci=1.10-1.34), higher charlson co-morbidity index score (or=1.13, ci=1.07-1.19), higher antipsychotic defined daily doses (or=3.05, ci=-2.95-3.16), treatment with clozapine (or=3.09, 95% ci=2.78-3.44), and treatment with antidepressants (or=1.97 (ci=1.83-2.13), long-acting injectable antipsychotics (or=1.48, ci=1.34-1.63), and anticholinergics (or=1.74, ci=1.51-2.01). |
2016-07-12 |
2023-08-13 |
Not clear |
| A Pereira, G Fink, S Sundra. Clozapine invokes the EGF system to activate ERK: a novel target in treatment resistant schizophrenia? Acta neuropsychiatrica. vol 18. issue 6. 2016-07-12. PMID:27397225. |
clozapine invokes the egf system to activate erk: a novel target in treatment resistant schizophrenia? |
2016-07-12 |
2023-08-13 |
Not clear |
| Jeannie D Lochhead, Michele A Nelson, Alan L Schneide. Risks and Benefits of Rapid Clozapine Titration. Mental illness. vol 8. issue 1. 2016-07-12. PMID:27403276. |
clozapine is often considered the gold standard for the treatment of schizophrenia. |
2016-07-12 |
2023-08-13 |
Not clear |
| Jeannie D Lochhead, Michele A Nelson, Alan L Schneide. Risks and Benefits of Rapid Clozapine Titration. Mental illness. vol 8. issue 1. 2016-07-12. PMID:27403276. |
we present the case of a young man with schizophrenia who developed life threatening neuroleptic malignant syndrome (nms) during rapid clozapine titration and treatment with multiple antipsychotics. |
2016-07-12 |
2023-08-13 |
Not clear |
| Jeannie D Lochhead, Michele A Nelson, Alan L Schneide. Risks and Benefits of Rapid Clozapine Titration. Mental illness. vol 8. issue 1. 2016-07-12. PMID:27403276. |
clozapine is considered the most effective antipsychotic available thus efforts should focus on developing strategies that would allow for safest and most efficient use of clozapine to encourage its utilization for treatment resistance schizophrenia. |
2016-07-12 |
2023-08-13 |
Not clear |
| Stéphane Potvin, Andràs Tikàsz, Ovidiu Lungu, Alexandre Dumais, Emmanuel Stip, Adrianna Mendre. Emotion processing in treatment-resistant schizophrenia patients treated with clozapine: An fMRI study. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26255082. |
emotion processing in treatment-resistant schizophrenia patients treated with clozapine: an fmri study. |
2016-07-06 |
2023-08-13 |
Not clear |
| Qian Li, Yu-Tao Xiang, Yun-Ai Su, Liang Shu, Xin Yu, Christoph U Correll, Gabor S Ungvari, Helen F K Chiu, Cui Ma, Gao-Hua Wang, Pei-Shen Bai, Tao Li, Li-Zhong Sun, Jian-Guo Shi, Xian-Sheng Chen, Qi-Yi Mei, Ke-Qing Li, Tian-Mei Si, John M Kan. Clozapine in schizophrenia and its association with treatment satisfaction and quality of life: Findings of the three national surveys on use of psychotropic medications in China (2002-2012). Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26277534. |
clozapine in schizophrenia and its association with treatment satisfaction and quality of life: findings of the three national surveys on use of psychotropic medications in china (2002-2012). |
2016-07-06 |
2023-08-13 |
Not clear |
| Qian Li, Yu-Tao Xiang, Yun-Ai Su, Liang Shu, Xin Yu, Christoph U Correll, Gabor S Ungvari, Helen F K Chiu, Cui Ma, Gao-Hua Wang, Pei-Shen Bai, Tao Li, Li-Zhong Sun, Jian-Guo Shi, Xian-Sheng Chen, Qi-Yi Mei, Ke-Qing Li, Tian-Mei Si, John M Kan. Clozapine in schizophrenia and its association with treatment satisfaction and quality of life: Findings of the three national surveys on use of psychotropic medications in China (2002-2012). Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26277534. |
we examined the time trends and correlates of clozapine use in schizophrenia patients in china. |
2016-07-06 |
2023-08-13 |
Not clear |
| Alfredo Spagna, Yi Dong, Melissa-Ann Mackie, Ming Li, Philip D Harvey, Yanghua Tian, Kai Wang, Jin Fa. Clozapine improves the orienting of attention in schizophrenia. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26298539. |
clozapine improves the orienting of attention in schizophrenia. |
2016-07-06 |
2023-08-13 |
Not clear |
| Alfredo Spagna, Yi Dong, Melissa-Ann Mackie, Ming Li, Philip D Harvey, Yanghua Tian, Kai Wang, Jin Fa. Clozapine improves the orienting of attention in schizophrenia. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26298539. |
we used the revised attention network test to measure alerting, orienting, and executive control of attention both pre- and post-treatment with clozapine in patients with schizophrenia (n=32) and compared performance to healthy controls (n=32). |
2016-07-06 |
2023-08-13 |
Not clear |