| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J-P Klemettilä, O Kampman, N Seppälä, M Viikki, M Hämäläinen, E Moilanen, N Mononen, T Lehtimäki, E Leinone. Association study of the HTR2C, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia. European psychiatry : the journal of the Association of European Psychiatrists. vol 30. issue 2. 2016-03-09. PMID:25284335. |
association study of the htr2c, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia. |
2016-03-09 |
2023-08-13 |
Not clear |
| J-P Klemettilä, O Kampman, N Seppälä, M Viikki, M Hämäläinen, E Moilanen, N Mononen, T Lehtimäki, E Leinone. Association study of the HTR2C, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia. European psychiatry : the journal of the Association of European Psychiatrists. vol 30. issue 2. 2016-03-09. PMID:25284335. |
clozapine treatment is associated with weight gain and cardio-metabolic consequences among patients with schizophrenia. |
2016-03-09 |
2023-08-13 |
Not clear |
| J-P Klemettilä, O Kampman, N Seppälä, M Viikki, M Hämäläinen, E Moilanen, N Mononen, T Lehtimäki, E Leinone. Association study of the HTR2C, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia. European psychiatry : the journal of the Association of European Psychiatrists. vol 30. issue 2. 2016-03-09. PMID:25284335. |
the aim of the present study was first to test for a possible role of serum leptin and adiponectin levels as a marker of weight gain in association with inflammatory cytokines/adipokines (il-6, il-1ra, hs-crp and adipsin), and second to study associations between snps lep rs7799039 (-2548 a/g), adipoq rs1501299 and htr2c rs1414334 and weight gain and levels of leptin and adiponectin, in 190 patients with schizophrenia on clozapine treatment, with retrospectively assessed weight change and cross-sectionally measured cytokine levels. |
2016-03-09 |
2023-08-13 |
Not clear |
| J-P Klemettilä, O Kampman, N Seppälä, M Viikki, M Hämäläinen, E Moilanen, N Mononen, T Lehtimäki, E Leinone. Association study of the HTR2C, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia. European psychiatry : the journal of the Association of European Psychiatrists. vol 30. issue 2. 2016-03-09. PMID:25284335. |
the results of the present study do not support a major role of snps lep rs7799039, adipoq rs1501299 and htr2c rs1414334 in the regulation of weight gain or association of serum levels of leptin and adiponectin and corresponding studied snps in patients with schizophrenia on clozapine treatment. |
2016-03-09 |
2023-08-13 |
Not clear |
| Anto P Rajkumar, B Poonkuzhali, Anju Kuruvilla, Alok Srivastava, Molly Jacob, K S Jaco. Association between CYP1A2 gene single nucleotide polymorphisms and clinical responses to clozapine in patients with treatment-resistant schizophrenia. Acta neuropsychiatrica. vol 25. issue 1. 2016-03-09. PMID:26953068. |
association between cyp1a2 gene single nucleotide polymorphisms and clinical responses to clozapine in patients with treatment-resistant schizophrenia. |
2016-03-09 |
2023-08-13 |
Not clear |
| Anto P Rajkumar, B Poonkuzhali, Anju Kuruvilla, Alok Srivastava, Molly Jacob, K S Jaco. Association between CYP1A2 gene single nucleotide polymorphisms and clinical responses to clozapine in patients with treatment-resistant schizophrenia. Acta neuropsychiatrica. vol 25. issue 1. 2016-03-09. PMID:26953068. |
despite clozapine's superior clinical efficacy in treatment-resistant schizophrenia (trs), its adverse effects, need for periodic leukocyte monitoring, cost and variable clinical outcomes mandate a clinical need to predict its treatment response. |
2016-03-09 |
2023-08-13 |
Not clear |
| Manit Srisurapanont, Sirijit Suttajit, Narong Maneeton, Benchalak Maneeto. Efficacy and safety of aripiprazole augmentation of clozapine in schizophrenia: a systematic review and meta-analysis of randomized-controlled trials. Journal of psychiatric research. vol 62. 2016-03-02. PMID:25619176. |
efficacy and safety of aripiprazole augmentation of clozapine in schizophrenia: a systematic review and meta-analysis of randomized-controlled trials. |
2016-03-02 |
2023-08-13 |
Not clear |
| Manit Srisurapanont, Sirijit Suttajit, Narong Maneeton, Benchalak Maneeto. Efficacy and safety of aripiprazole augmentation of clozapine in schizophrenia: a systematic review and meta-analysis of randomized-controlled trials. Journal of psychiatric research. vol 62. 2016-03-02. PMID:25619176. |
limited options are available for clozapine-resistant schizophrenia and intolerable side effects of clozapine. |
2016-03-02 |
2023-08-13 |
Not clear |
| Manit Srisurapanont, Sirijit Suttajit, Narong Maneeton, Benchalak Maneeto. Efficacy and safety of aripiprazole augmentation of clozapine in schizophrenia: a systematic review and meta-analysis of randomized-controlled trials. Journal of psychiatric research. vol 62. 2016-03-02. PMID:25619176. |
we conducted a systematic review of randomized-controlled trials (rcts) to determine the efficacy and safety of aripiprazole augmentation of clozapine for schizophrenia. |
2016-03-02 |
2023-08-13 |
Not clear |
| Adam Wysokiński, Jakub Kaźmierski, Iwona Kłoszewsk. Serum levels of AgRP protein in patients with schizophrenia on clozapine monotherapy. Metabolic brain disease. vol 30. issue 2. 2016-03-01. PMID:25034457. |
serum levels of agrp protein in patients with schizophrenia on clozapine monotherapy. |
2016-03-01 |
2023-08-13 |
human |
| Adam Wysokiński, Jakub Kaźmierski, Iwona Kłoszewsk. Serum levels of AgRP protein in patients with schizophrenia on clozapine monotherapy. Metabolic brain disease. vol 30. issue 2. 2016-03-01. PMID:25034457. |
the aim of the study was to find out if agrp level in subjects with schizophrenia on clozapine monotherapy is higher compared with healthy controls. |
2016-03-01 |
2023-08-13 |
human |
| Memduha Aydin, Bilge Cetin Ilhan, Saliha Calisir, Seda Yildirim, Ibrahim Ere. Continuing clozapine treatment with lithium in schizophrenic patients with neutropenia or leukopenia: brief review of literature with case reports. Therapeutic advances in psychopharmacology. vol 6. issue 1. 2016-02-25. PMID:26913176. |
clozapine is a second-generation antipsychotic used for treatment-resistant schizophrenia. |
2016-02-25 |
2023-08-13 |
Not clear |
| Antonio Bruno, Rocco Zoccali, Paolo Micali Bellinghieri, Gianluca Pandolfo, Pasquale De Fazio, Edoardo Spina, Maria Rosaria A Muscatell. Reboxetine adjuvant therapy in patients with schizophrenia showing a suboptimal response to clozapine: a 12-week, open-label, pilot study. Journal of clinical psychopharmacology. vol 34. issue 5. 2016-02-24. PMID:25118083. |
reboxetine adjuvant therapy in patients with schizophrenia showing a suboptimal response to clozapine: a 12-week, open-label, pilot study. |
2016-02-24 |
2023-08-13 |
Not clear |
| Antonio Bruno, Rocco Zoccali, Paolo Micali Bellinghieri, Gianluca Pandolfo, Pasquale De Fazio, Edoardo Spina, Maria Rosaria A Muscatell. Reboxetine adjuvant therapy in patients with schizophrenia showing a suboptimal response to clozapine: a 12-week, open-label, pilot study. Journal of clinical psychopharmacology. vol 34. issue 5. 2016-02-24. PMID:25118083. |
the present 12-week open-label uncontrolled trial was aimed to explore the efficacy of reboxetine add-on pharmacotherapy on clinical symptoms and cognitive functioning in 15 patients with schizophrenia with suboptimal response (mean [sd] brief psychiatric rating scale baseline total score, 32.2 [5.4]) despite receiving clozapine monotherapy at the highest tolerated dosage. |
2016-02-24 |
2023-08-13 |
Not clear |
| Antonio Bruno, Rocco Zoccali, Paolo Micali Bellinghieri, Gianluca Pandolfo, Pasquale De Fazio, Edoardo Spina, Maria Rosaria A Muscatell. Reboxetine adjuvant therapy in patients with schizophrenia showing a suboptimal response to clozapine: a 12-week, open-label, pilot study. Journal of clinical psychopharmacology. vol 34. issue 5. 2016-02-24. PMID:25118083. |
after bonferroni correction, changes at the calgary depression scale for schizophrenia and at the verbal fluency task were not further confirmed.the results obtained indicate that reboxetine seemed to be scarcely effective for reducing clinical symptoms in patients with schizophrenia who have had an incomplete clinical response to clozapine. |
2016-02-24 |
2023-08-13 |
Not clear |
| Tyler S Kaster, Danilo de Jesus, Natasha Radhu, Faranak Farzan, Daniel M Blumberger, Tarek K Rajji, Paul B Fitzgerald, Zafiris J Daskalaki. Clozapine potentiation of GABA mediated cortical inhibition in treatment resistant schizophrenia. Schizophrenia research. vol 165. issue 2-3. 2016-02-22. PMID:25957485. |
clozapine potentiation of gaba mediated cortical inhibition in treatment resistant schizophrenia. |
2016-02-22 |
2023-08-13 |
Not clear |
| Clare Louise Chapman, Matthew Michael Larg. Should clozapine be available to people with early schizophrenia and suicidal ideation? The Australian and New Zealand journal of psychiatry. vol 49. issue 4. 2016-02-19. PMID:25526942. |
should clozapine be available to people with early schizophrenia and suicidal ideation? |
2016-02-19 |
2023-08-13 |
Not clear |
| Siobhan Gee, Thomas Dixon, Mary Docherty, Sukhwinder S Shergil. Optimising plasma levels of clozapine during metabolic interactions: a review and case report with adjunct rifampicin treatment. BMC psychiatry. vol 15. 2016-02-19. PMID:26265348. |
clozapine is the only licensed medication for treatment-resistant schizophrenia. |
2016-02-19 |
2023-08-13 |
Not clear |
| Nancy J Butcher, Wai Lun Alan Fung, Laura Fitzpatrick, Alina Guna, Danielle M Andrade, Anthony E Lang, Eva W C Chow, Anne S Basset. Response to clozapine in a clinically identifiable subtype of schizophrenia. The British journal of psychiatry : the journal of mental science. vol 206. issue 6. 2016-02-16. PMID:25745132. |
response to clozapine in a clinically identifiable subtype of schizophrenia. |
2016-02-16 |
2023-08-13 |
Not clear |
| Carolina Schneider, Efstathios Papachristou, Theresa Wimberley, Christiane Gasse, Danai Dima, James H MacCabe, Preben Bo Mortensen, Sophia Frango. Clozapine use in childhood and adolescent schizophrenia: A nationwide population-based study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 6. 2016-02-16. PMID:25769917. |
clozapine use in childhood and adolescent schizophrenia: a nationwide population-based study. |
2016-02-16 |
2023-08-13 |
Not clear |