| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hidenaga Yamamori, Ryota Hashimoto, Yuko Fujita, Shusuke Numata, Yuka Yasuda, Michiko Fujimoto, Kazutaka Ohi, Satomi Umeda-Yano, Akira Ito, Tetsuro Ohmori, Kenji Hashimoto, Masatoshi Taked. Changes in plasma D-serine, L-serine, and glycine levels in treatment-resistant schizophrenia before and after clozapine treatment. Neuroscience letters. vol 582. 2015-05-26. PMID:25218715. |
this study firstly demonstrated changes of d-/l-serine and glycine/l-serine ratio between before and after clozapine treatment, suggesting that the plasma d-/l-serine ratio and glycine/l-serine ratio could be markers of therapeutic efficacy or clinical state in treatment-resistant schizophrenia. |
2015-05-26 |
2023-08-13 |
Not clear |
| S R T Veerman, P F J Schulte, M J H Begemann, F Engelsbel, L de Haa. Clozapine augmented with glutamate modulators in refractory schizophrenia: a review and metaanalysis. Pharmacopsychiatry. vol 47. issue 6. 2015-05-11. PMID:25002291. |
clozapine augmented with glutamate modulators in refractory schizophrenia: a review and metaanalysis. |
2015-05-11 |
2023-08-13 |
Not clear |
| Ming-Kung Wu, Weilun Chung, Ching-Kuan Wu, Ping-Tao Tsen. The severe complication of Stevens-Johnson syndrome induced by long-term clozapine treatment in a male schizophrenia patient: a case report. Neuropsychiatric disease and treatment. vol 11. 2015-04-28. PMID:25914536. |
the severe complication of stevens-johnson syndrome induced by long-term clozapine treatment in a male schizophrenia patient: a case report. |
2015-04-28 |
2023-08-13 |
Not clear |
| Ippei Takeuchi, Tatsuyo Suzuki, Taro Kishi, Daisuke Kanamori, Manako Hanya, Junji Uno, Kiyoshi Fujita, Hiroyuki Kame. Effect of Scopolamine Butylbromide on Clozapine-induced Hypersalivation in Schizophrenic Patients: A Case Series. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 13. issue 1. 2015-04-27. PMID:25912544. |
clozapine has been demonstrated to be useful for treating refractory schizophrenia. |
2015-04-27 |
2023-08-13 |
Not clear |
| R Madelaine Paredes, Marlon Quinones, Ketan Marballi, Xiaoli Gao, Celina Valdez, Seema S Ahuja, Dawn Velligan, Consuelo Walss-Bas. Metabolomic profiling of schizophrenia patients at risk for metabolic syndrome. The international journal of neuropsychopharmacology. vol 17. issue 8. 2015-04-14. PMID:24565079. |
we performed a comprehensive metabolomic profiling of 60 schizophrenia patients undergoing treatment with sgas that puts them at high (clozapine, olanzapine), medium (quetiapine, risperidone), or low (ziprasidone, aripiprazole) risk for developing mets, compared to a cohort of 20 healthy controls. |
2015-04-14 |
2023-08-12 |
Not clear |
| K Kontoangelos, S Loizos, J Kanakakis, N Smyrnis, M Economou, J D Bergiannaki, G N Papadimitrio. Myocarditis after administration of clozapine. European review for medical and pharmacological sciences. vol 18. issue 16. 2015-04-06. PMID:25219841. |
clozapine is an atypical antpsychotic medication with established efficacy in patients diagnosed of resistant schizophrenia. |
2015-04-06 |
2023-08-13 |
Not clear |
| Fabiani Bogorni, Frederico Fernandes Moreira, Eduardo Mylius Pimentel, Géder Evandro Motta Grohs, Alexandre Paim Dia. Amisulpride augmentation for clozapine-refractory positive symptoms: additional benefit in reducing hypersialorrhea. Case reports in psychiatry. vol 2015. 2015-04-03. PMID:25838958. |
this is a case of a 30-year-old male with refractory schizophrenia; in this patient, the remission of residual positive symptoms, as well as the reduction of cih, was achieved by treatment with clozapine augmented with amisulpride. |
2015-04-03 |
2023-08-13 |
Not clear |
| Jitender Aneja, Nidhi Sharma, Sudhir Mahajan, Subho Chakrabarti, Sandeep Grove. Eosinophilia induced by clozapine: a report of two cases and review of the literature. Journal of family medicine and primary care. vol 4. issue 1. 2015-03-26. PMID:25811003. |
clozapine, an atypical antipsychotic, has been used in the treatment of schizophrenia and other psychotic disorders. |
2015-03-26 |
2023-08-13 |
Not clear |
| Anssi Solismaa, Olli Kampman, Niko Seppälä, Merja Viikki, Kari-Matti Mäkelä, Nina Mononen, Terho Lehtimäki, Esa Leinone. Polymorphism in alpha 2A adrenergic receptor gene is associated with sialorrhea in schizophrenia patients on clozapine treatment. Human psychopharmacology. vol 29. issue 4. 2015-03-13. PMID:25163438. |
polymorphism in alpha 2a adrenergic receptor gene is associated with sialorrhea in schizophrenia patients on clozapine treatment. |
2015-03-13 |
2023-08-13 |
Not clear |
| Georgios Petrides, Chitra Malur, Raphael J Braga, Samuel H Bailine, Nina R Schooler, Anil K Malhotra, John M Kane, Sohag Sanghani, Terry E Goldberg, Majnu John, Alan Mendelowit. Electroconvulsive therapy augmentation in clozapine-resistant schizophrenia: a prospective, randomized study. The American journal of psychiatry. vol 172. issue 1. 2015-03-11. PMID:25157964. |
up to 70% of patients with treatment-resistant schizophrenia do not respond to clozapine. |
2015-03-11 |
2023-08-13 |
Not clear |
| Georgios Petrides, Chitra Malur, Raphael J Braga, Samuel H Bailine, Nina R Schooler, Anil K Malhotra, John M Kane, Sohag Sanghani, Terry E Goldberg, Majnu John, Alan Mendelowit. Electroconvulsive therapy augmentation in clozapine-resistant schizophrenia: a prospective, randomized study. The American journal of psychiatry. vol 172. issue 1. 2015-03-11. PMID:25157964. |
the authors examined the use of ect as an augmentation to clozapine for treatment-refractory schizophrenia. |
2015-03-11 |
2023-08-13 |
Not clear |
| Christina Voulgari, Raphael Giannas, Georgios Paterakis, Anna Kanellou, Nikolaos Anagnostopoulos, Stamata Pagon. Clozapine-Induced Late Agranulocytosis and Severe Neutropenia Complicated with Streptococcus pneumonia, Venous Thromboembolism, and Allergic Vasculitis in Treatment-Resistant Female Psychosis. Case reports in medicine. vol 2015. 2015-03-10. PMID:25755670. |
clozapine is a second-generation antipsychotic agent from the benzodiazepine group indicated for treatment-resistant schizophrenia and other psychotic conditions. |
2015-03-10 |
2023-08-13 |
Not clear |
| Aaron Jenkins, José A Apud, Fengyu Zhang, Heather Decot, Daniel R Weinberger, Amanda J La. Identification of candidate single-nucleotide polymorphisms in NRXN1 related to antipsychotic treatment response in patients with schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 9. 2015-03-02. PMID:24633560. |
based on previous suggestive evidence of an impact on clozapine response in patients with schizophrenia, we conducted an association study of nrxn1 polymorphisms (rs12467557 and rs10490162) with antipsychotic treatment response in 54 patients with schizophrenia in a double blind, placebo-controlled nimh inpatient crossover trial and examined for association with risk for schizophrenia in independent case-control and family-based clinical cohorts. |
2015-03-02 |
2023-08-12 |
Not clear |
| Cuiping Yang, Changchun Cai, Xiaojin Yang, Yanping Yang, Zhigang Zhou, Jianhua Liu, Heping Ye, Hongjiao Wa. Wendan decoction improves learning and memory deficits in a rat model of schizophrenia. Neural regeneration research. vol 7. issue 15. 2015-02-27. PMID:25722705. |
the results revealed that the latency of schizophrenia model rats to escape from the hidden platform in the morris water maze was significantly shortened after administration of wendan decoction or clozapine. |
2015-02-27 |
2023-08-13 |
rat |
| Marcos Leite Santoro, Vanessa Kiyomi Ota, Roberta Sessa Stilhano, Patrícia Natália Silva, Camila Maurício Santos, Mariana Cepollaro Diana, Ary Gadelha, Rodrigo Affonseca Bressan, Maria Isabel Melaragno, Sang Won Han, Vanessa Costhek Abílio, Sintia Iole Belanger. Effect of antipsychotic drugs on gene expression in the prefrontal cortex and nucleus accumbens in the spontaneously hypertensive rat (SHR). Schizophrenia research. vol 157. issue 1-3. 2015-02-26. PMID:24893910. |
each group was treated with a different apd (risperidone, clozapine or haloperidol), and with a non-treated group of spontaneously hypertensive rats (shrs), which is an animal model for schizophrenia. |
2015-02-26 |
2023-08-13 |
rat |
| Jimmy Lee, Valerie Powell, Gary Remingto. Mean platelet volume in schizophrenia unaltered after 1year of clozapine exposure. Schizophrenia research. vol 157. issue 1-3. 2015-02-26. PMID:24906221. |
mean platelet volume in schizophrenia unaltered after 1year of clozapine exposure. |
2015-02-26 |
2023-08-13 |
Not clear |
| Jimmy Lee, Valerie Powell, Gary Remingto. Mean platelet volume in schizophrenia unaltered after 1year of clozapine exposure. Schizophrenia research. vol 157. issue 1-3. 2015-02-26. PMID:24906221. |
we found high mpv in patients with schizophrenia and related psychoses, which was unaltered after 1year of clozapine treatment. |
2015-02-26 |
2023-08-13 |
Not clear |
| S Gee, F Vergunst, O Howes, D Taylo. Practitioner attitudes to clozapine initiation. Acta psychiatrica Scandinavica. vol 130. issue 1. 2015-02-12. PMID:24004162. |
clozapine is the most effective antipsychotic for treatment-resistant schizophrenia. |
2015-02-12 |
2023-08-12 |
Not clear |
| M C Davis, M A Fuller, M E Strauss, P E Konicki, G E Jaski. Discontinuation of clozapine: a 15-year naturalistic retrospective study of 320 patients. Acta psychiatrica Scandinavica. vol 130. issue 1. 2015-02-12. PMID:24299466. |
clozapine is underutilized in the management of treatment-resistant schizophrenia. |
2015-02-12 |
2023-08-12 |
Not clear |
| P Ifteni, J Nielsen, V Burtea, C U Correll, J M Kane, P Man. Effectiveness and safety of rapid clozapine titration in schizophrenia. Acta psychiatrica Scandinavica. vol 130. issue 1. 2015-02-12. PMID:24354448. |
effectiveness and safety of rapid clozapine titration in schizophrenia. |
2015-02-12 |
2023-08-12 |
Not clear |