Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
J-M Batail, B Langrée, G Robert, S Bleher, M-C Verdier, E Bellissant, B Millet, D Drapie. Use of very-high-dose olanzapine in treatment-resistant schizophrenia. Schizophrenia research. vol 159. issue 2-3. 2015-08-19. PMID:25278103. |
in the literature, treatment with high-dose olanzapine (>20mg/day) appears to be a good alternative to clozapine, the gold standard for treatment-resistant schizophrenia. |
2015-08-19 |
2023-08-13 |
Not clear |
Adam Wysokińsk. Blood levels of glucose and insulin and insulin resistance in patients with schizophrenia on clozapine monotherapy. Diabetes & metabolic syndrome. vol 8. issue 4. 2015-08-17. PMID:25311817. |
blood levels of glucose and insulin and insulin resistance in patients with schizophrenia on clozapine monotherapy. |
2015-08-17 |
2023-08-13 |
human |
Pasquale De Fazio, Raffaele Gaetano, Mariarita Caroleo, Gregorio Cerminara, Francesca Maida, Antonio Bruno, Maria Rosaria Muscatello, Maria Jose Jaén Moreno, Emilio Russo, Cristina Segura-Garcí. Rare and very rare adverse effects of clozapine. Neuropsychiatric disease and treatment. vol 11. 2015-08-14. PMID:26273202. |
clozapine (clz) is the drug of choice for the treatment of resistant schizophrenia; however, its suitable use is limited by the complex adverse effects' profile. |
2015-08-14 |
2023-08-13 |
Not clear |
Li Hui, Minjie Ye, Wei Tang, Feixue Zhang, Jiahong Liu, Linjing Liu, Yuanling Chen, Da-Chun Chen, Yun-Long Tan, Fu-De Yang, Xiang Yang Zhan. Obesity correlates with fewer symptoms in schizophrenia treated with long-term clozapine: gender difference. Psychiatry research. vol 225. issue 3. 2015-08-11. PMID:25595339. |
obesity correlates with fewer symptoms in schizophrenia treated with long-term clozapine: gender difference. |
2015-08-11 |
2023-08-13 |
Not clear |
Dawn Bruijnzeel, Uma Suryadevara, Rajiv Tando. Antipsychotic treatment of schizophrenia: an update. Asian journal of psychiatry. vol 11. 2015-08-10. PMID:25216917. |
whereas clozapine is found to be more efficacious than other agents among otherwise treatment-refractory schizophrenia patients, other differences in efficacy between antipsychotic agents are minor. |
2015-08-10 |
2023-08-13 |
Not clear |
Adam Wysokiński, Marek L Kowalski, Iwona Kłoszewsk. Serum levels of desacyl ghrelin in patients with schizophrenia on clozapine monotherapy. Psychiatry and clinical neurosciences. vol 68. issue 12. 2015-08-03. PMID:24773632. |
serum levels of desacyl ghrelin in patients with schizophrenia on clozapine monotherapy. |
2015-08-03 |
2023-08-13 |
Not clear |
Lin Yang, Jianhua Chen, Dengtang Liu, Shunying Yu, Enzhao Cong, Yan Li, Haisu Wu, Ying Yue, Sai Zuo, Yan Wang, Shiqiao Liang, Yongyong Shi, Shenxun Shi, Yifeng X. Association between SREBF2 gene polymorphisms and metabolic syndrome in clozapine-treated patients with schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 56. 2015-07-31. PMID:25201120. |
patients with schizophrenia using antipsychotics often develop metabolic side effects, especially with clozapine. |
2015-07-31 |
2023-08-13 |
Not clear |
Young Sup Woo, Hee-Ryung Wang, Bo-Hyun Yoon, Sang-Yeol Lee, Kwang Hun Lee, Jeong Seok Seo, Won-Myong Bah. Bioequivalence of Generic and Brand Name Clozapine in Korean Schizophrenic Patients: A Randomized, Two-Period, Crossover Study. Psychiatry investigation. vol 12. issue 3. 2015-07-24. PMID:26207129. |
clozapine is the treatment of choice for refractory schizophrenia. |
2015-07-24 |
2023-08-13 |
Not clear |
Souhail Bannour, Saoussen Bouhlel, Mohamed Wassim Krir, Badii Amamou, Selma Ben Nasr, Yousri El Kissi, Bechir Ben Hadj Al. Combination of maintenance electroconvulsive therapy and clozapine in treating a patient with refractory schizophrenia. The journal of ECT. vol 30. issue 3. 2015-07-20. PMID:24820944. |
combination of maintenance electroconvulsive therapy and clozapine in treating a patient with refractory schizophrenia. |
2015-07-20 |
2023-08-13 |
Not clear |
Jimmy Lee, Hiroyoshi Takeuchi, Gagan Fervaha, Amaal Bhaloo, Valerie Powell, Gary Remingto. Relationship between clinical improvement and functional gains with clozapine in schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 10. 2015-07-14. PMID:25156578. |
relationship between clinical improvement and functional gains with clozapine in schizophrenia. |
2015-07-14 |
2023-08-13 |
human |
Jimmy Lee, Hiroyoshi Takeuchi, Gagan Fervaha, Amaal Bhaloo, Valerie Powell, Gary Remingto. Relationship between clinical improvement and functional gains with clozapine in schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 10. 2015-07-14. PMID:25156578. |
we examined the relationship between change in symptoms and change in functioning in a group of patients with treatment-resistant schizophrenia after 6 and 12 weeks of clozapine treatment. |
2015-07-14 |
2023-08-13 |
human |
S R T Veerman, P F J Schulte, M J H Begemann, L de Haa. Non-glutamatergic clozapine augmentation strategies: a review and meta-analysis. Pharmacopsychiatry. vol 47. issue 7. 2015-07-06. PMID:25121994. |
there is no convincing evidence regarding the efficacy of augmentation of clozapine with a second antipsychotic, ethyl eicosapentaenoic acid (e-epa), an antidepressant, a mood stabilizer or extract of ginkgo biloba in clozapine-resistant schizophrenia. |
2015-07-06 |
2023-08-13 |
Not clear |
S R T Veerman, P F J Schulte, M J H Begemann, L de Haa. Non-glutamatergic clozapine augmentation strategies: a review and meta-analysis. Pharmacopsychiatry. vol 47. issue 7. 2015-07-06. PMID:25121994. |
we compared the effects of the addition of a second antipsychotic or an antidepressant to clozapine on positive, negative, overall and affective symptoms of schizophrenia in double-blind placebo-controlled trials. |
2015-07-06 |
2023-08-13 |
Not clear |
Veeramanikandan Rajagopal, Lakshmikirupa Sundaresan, Anto P Rajkumar, Chithra Chittybabu, Anju Kuruvilla, Alok Srivastava, Poonkuzhali Balasubramanian, Kuruthukulangara S Jacob, Molly Jaco. Genetic association between the DRD4 promoter polymorphism and clozapine-induced sialorrhea. Psychiatric genetics. vol 24. issue 6. 2015-06-25. PMID:25304228. |
ninety-five patients, mean age 35.43±9.43 years, with treatment-resistant schizophrenia and on clozapine were included in the study. |
2015-06-25 |
2023-08-13 |
Not clear |
Paria Hebrani, Ali Akhoundpour Manteghi, Fatemeh Behdani, Elham Hessami, Kambiz Akhavan Rezayat, Majid Nabizadeh Marvast, Amir Akhavan Rezaya. Double-blind, randomized, clinical trial of metformin as add-on treatment with clozapine in treatment of schizophrenia disorder. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences. vol 20. issue 4. 2015-06-25. PMID:26109992. |
double-blind, randomized, clinical trial of metformin as add-on treatment with clozapine in treatment of schizophrenia disorder. |
2015-06-25 |
2023-08-13 |
Not clear |
Paria Hebrani, Ali Akhoundpour Manteghi, Fatemeh Behdani, Elham Hessami, Kambiz Akhavan Rezayat, Majid Nabizadeh Marvast, Amir Akhavan Rezaya. Double-blind, randomized, clinical trial of metformin as add-on treatment with clozapine in treatment of schizophrenia disorder. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences. vol 20. issue 4. 2015-06-25. PMID:26109992. |
we aimed to investigate the effect of metformin as an adjunctive therapy with clozapine to prevent metabolic syndrome in patients with schizophrenia. |
2015-06-25 |
2023-08-13 |
Not clear |
Ruohollah Seddigh, Somayeh Azarnik, Amir-Abbas Keshavarz-Akhlagh. Levothyroxine Augmentation in Clozapine Resistant Schizophrenia: A Case Report and Review. Case reports in psychiatry. vol 2015. 2015-06-16. PMID:26078905. |
levothyroxine augmentation in clozapine resistant schizophrenia: a case report and review. |
2015-06-16 |
2023-08-13 |
Not clear |
Ruohollah Seddigh, Somayeh Azarnik, Amir-Abbas Keshavarz-Akhlagh. Levothyroxine Augmentation in Clozapine Resistant Schizophrenia: A Case Report and Review. Case reports in psychiatry. vol 2015. 2015-06-16. PMID:26078905. |
this case report outlines symptom subsidence of a patient with clozapine refractory paranoid schizophrenia and normal thyroid function who added levothyroxine to clozapine and found that symptoms of psychosis returned once levothyroxine was discontinued. |
2015-06-16 |
2023-08-13 |
Not clear |
Mohammed Alawami, Cara Wasywich, Aleksandar Cicovic, Christopher Kened. A systematic review of clozapine induced cardiomyopathy. International journal of cardiology. vol 176. issue 2. 2015-06-15. PMID:25131906. |
clozapine is a unique anti-psychotic medication that is most effective in the treatment of refractory schizophrenia and reducing suicidality. |
2015-06-15 |
2023-08-13 |
human |
Niko Seppälä, Esa Leinonen, Merja Viikki, Olli Kampma. Smoking and weight among patients using clozapine. Nordic journal of psychiatry. vol 68. issue 8. 2015-06-08. PMID:24802120. |
both obesity and smoking are common in schizophrenia patients taking clozapine, causing cardiovascular disease and premature deaths. |
2015-06-08 |
2023-08-13 |
Not clear |