| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antonio Bruno, Rocco A Zoccali, Elisabetta Abenavoli, Gianluca Pandolfo, Giuseppe Scimeca, Edoardo Spina, Maria Rosaria Anna Muscatell. Augmentation of clozapine with agomelatine in partial-responder schizophrenia: a 16-week, open-label, uncontrolled pilot study. Journal of clinical psychopharmacology. vol 34. issue 4. 2015-09-28. PMID:24911437. |
the present 16-week open-label uncontrolled trial was aimed to explore the efficacy of adjunctive agomelatine on clinical symptoms and cognitive functioning in 20 schizophrenia patients showing partial response (brief psychiatric rating scale, mean [sd] baseline total score = 37.5 [6.6]) to clozapine monotherapy at the highest tolerated dosage. |
2015-09-28 |
2023-08-13 |
Not clear |
| Shani Pridan, Marnina Swartz, Yehuda Baruch, Shelly Tadger, Igor Plopski, Yoram Bara. Effectiveness and safety of clozapine in elderly patients with chronic resistant schizophrenia. International psychogeriatrics. vol 27. issue 1. 2015-09-28. PMID:25166892. |
effectiveness and safety of clozapine in elderly patients with chronic resistant schizophrenia. |
2015-09-28 |
2023-08-13 |
Not clear |
| Shani Pridan, Marnina Swartz, Yehuda Baruch, Shelly Tadger, Igor Plopski, Yoram Bara. Effectiveness and safety of clozapine in elderly patients with chronic resistant schizophrenia. International psychogeriatrics. vol 27. issue 1. 2015-09-28. PMID:25166892. |
we aimed to evaluate the effectiveness and safety of clozapine monotherapy in a diagnostically homogeneous group of elderly patients suffering from schizophrenia (dsm-iv-tr criteria). |
2015-09-28 |
2023-08-13 |
Not clear |
| Praveen Tripathi, Priyanka Goyal, Deepak Kumar, Om Prakas. High doses of aripiprazole therapy for a patient with treatment-resistant schizophrenia responsive to, but intolerant of, clozapine. The Australian and New Zealand journal of psychiatry. vol 49. issue 2. 2015-09-28. PMID:25217184. |
high doses of aripiprazole therapy for a patient with treatment-resistant schizophrenia responsive to, but intolerant of, clozapine. |
2015-09-28 |
2023-08-13 |
Not clear |
| Kazuaki Kawaura, Hiroyuki Koike, Kohnosuke Kinoshita, Daiji Kambe, Ayaka Kaku, Jun-ichi Karasawa, Shigeyuki Chaki, Hirohiko Hikich. Effects of a glycine transporter-1 inhibitor and D-serine on MK-801-induced immobility in the forced swimming test in rats. Behavioural brain research. vol 278. 2015-09-28. PMID:25300471. |
the increased immobility induced by mk-801 was attenuated by the atypical antipsychotic clozapine but not by either the typical antipsychotic haloperidol or the antidepressant imipramine, indicating that the increased immobility induced by subchronic treatment with mk-801 in the forced swimming test may represent a negative symptom of schizophrenia. |
2015-09-28 |
2023-08-13 |
rat |
| T Godoy, A Riva, J Ekströ. Salivary secretion effects of the antipsychotic drug olanzapine in an animal model. Oral diseases. vol 19. issue 2. 2015-09-23. PMID:22816733. |
olanzapine, introduced as an alternative to clozapine in schizophrenia therapy, is thought to display a receptor affinity similar to that of clozapine. |
2015-09-23 |
2023-08-12 |
Not clear |
| Giovana J Garcia, Marcos H Chagas, Carlos H Silva, João P Machado-de-Sousa, José A Crippa, Jaime E Halla. Structural and functional neuroimaging findings associated with the use of clozapine in schizophrenia: a systematic review. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). vol 37. issue 1. 2015-09-22. PMID:25806554. |
structural and functional neuroimaging findings associated with the use of clozapine in schizophrenia: a systematic review. |
2015-09-22 |
2023-08-13 |
Not clear |
| Giovana J Garcia, Marcos H Chagas, Carlos H Silva, João P Machado-de-Sousa, José A Crippa, Jaime E Halla. Structural and functional neuroimaging findings associated with the use of clozapine in schizophrenia: a systematic review. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). vol 37. issue 1. 2015-09-22. PMID:25806554. |
clozapine is an atypical antipsychotic with a specific profile of action indicated for treatment-resistant schizophrenia. |
2015-09-22 |
2023-08-13 |
Not clear |
| Vikram Oke, Frances Schmidt, Bikash Bhattarai, Md Basunia, Chidozie Agu, Amrit Kaur, Danilo Enriquez, Joseph Quist, Divya Salhan, Vijay Gayam, Prajakta Mungika. Unrecognized clozapine-related constipation leading to fatal intra-abdominal sepsis - a case report. International medical case reports journal. vol 8. 2015-09-22. PMID:26392790. |
clozapine is the preferred antipsychotic used for the treatment of resistant schizophrenia with suicidal ideation. |
2015-09-22 |
2023-08-13 |
Not clear |
| Marta Bosia, Cristina Lorenzi, Adele Pirovano, Carmelo Guglielmino, Federica Cocchi, Marco Spangaro, Placido Bramanti, Enrico Smeraldi, Roberto Cavallar. COMT Val158Met and 5-HT1A-R -1019 C/G polymorphisms: effects on the negative symptom response to clozapine. Pharmacogenomics. vol 16. issue 1. 2015-09-16. PMID:25560469. |
clozapine is still considered the gold standard for treatment-resistant schizophrenia patients; however, up to 40% of patients do not respond adequately. |
2015-09-16 |
2023-08-13 |
Not clear |
| Adam Wysokińsk. Fasting serum levels of neuropeptide y in patients with schizophrenia on clozapine monotherapy. Clinical neuropharmacology. vol 38. issue 1. 2015-09-04. PMID:25580919. |
fasting serum levels of neuropeptide y in patients with schizophrenia on clozapine monotherapy. |
2015-09-04 |
2023-08-13 |
human |
| Adam Wysokińsk. Fasting serum levels of neuropeptide y in patients with schizophrenia on clozapine monotherapy. Clinical neuropharmacology. vol 38. issue 1. 2015-09-04. PMID:25580919. |
we checked whether npy level in subjects with schizophrenia on clozapine is higher compared with healthy controls. |
2015-09-04 |
2023-08-13 |
human |
| O Schjerning, S Lykkegaard, P Damkier, J Nielse. Possible drug-drug interaction between pregabalin and clozapine in patients with schizophrenia: clinical perspectives. Pharmacopsychiatry. vol 48. issue 1. 2015-09-01. PMID:25295553. |
possible drug-drug interaction between pregabalin and clozapine in patients with schizophrenia: clinical perspectives. |
2015-09-01 |
2023-08-13 |
Not clear |
| F A Mustafa, J G Burke, S S Abukmeil, J J Scanlon, M Co. "Schizophrenia past clozapine": reasons for clozapine discontinuation, mortality, and alternative antipsychotic prescribing. Pharmacopsychiatry. vol 48. issue 1. 2015-09-01. PMID:25376977. |
"schizophrenia past clozapine": reasons for clozapine discontinuation, mortality, and alternative antipsychotic prescribing. |
2015-09-01 |
2023-08-13 |
Not clear |
| F A Mustafa, J G Burke, S S Abukmeil, J J Scanlon, M Co. "Schizophrenia past clozapine": reasons for clozapine discontinuation, mortality, and alternative antipsychotic prescribing. Pharmacopsychiatry. vol 48. issue 1. 2015-09-01. PMID:25376977. |
the clinical records of 190 patients with schizophrenia who discontinued clozapine between 1990 and 2012 in the county of northamptonshire were examined, in an attempt to answer the following questions. |
2015-09-01 |
2023-08-13 |
Not clear |
| Winnie Ng, Rossoune Kennar, Jack Uetrech. Effect of clozapine and olanzapine on neutrophil kinetics: implications for drug-induced agranulocytosis. Chemical research in toxicology. vol 27. issue 7. 2015-08-31. PMID:24968069. |
clozapine is effective in the treatment of schizophrenia; however, its use is limited by a relatively high incidence of idiosyncratic agranulocytosis. |
2015-08-31 |
2023-08-13 |
rat |
| Tarek K Rajji, Benoit H Mulsant, Simon Davies, Sawsan M Kalache, Christopher Tsoutsoulas, Bruce G Pollock, Gary Remingto. Prediction of working memory performance in schizophrenia by plasma ratio of clozapine to N-desmethylclozapine. The American journal of psychiatry. vol 172. issue 6. 2015-08-24. PMID:25859763. |
prediction of working memory performance in schizophrenia by plasma ratio of clozapine to n-desmethylclozapine. |
2015-08-24 |
2023-08-13 |
Not clear |
| Tarek K Rajji, Benoit H Mulsant, Simon Davies, Sawsan M Kalache, Christopher Tsoutsoulas, Bruce G Pollock, Gary Remingto. Prediction of working memory performance in schizophrenia by plasma ratio of clozapine to N-desmethylclozapine. The American journal of psychiatry. vol 172. issue 6. 2015-08-24. PMID:25859763. |
clozapine's potent antagonism of muscarinic m1 receptors is thought to worsen working memory deficits associated with schizophrenia. |
2015-08-24 |
2023-08-13 |
Not clear |
| Tarek K Rajji, Benoit H Mulsant, Simon Davies, Sawsan M Kalache, Christopher Tsoutsoulas, Bruce G Pollock, Gary Remingto. Prediction of working memory performance in schizophrenia by plasma ratio of clozapine to N-desmethylclozapine. The American journal of psychiatry. vol 172. issue 6. 2015-08-24. PMID:25859763. |
the authors hypothesized that the ratio of serum clozapine and ndmc concentrations would be inversely associated with working memory performance in schizophrenia. |
2015-08-24 |
2023-08-13 |
Not clear |
| Ruth Murphy, Anne Gallagher, Kapil Sharma, Tariq Ali, Elizabeth Lewis, Ivan Murray, Brian Hallaha. Clozapine-induced stuttering: an estimate of prevalence in the west of Ireland. Therapeutic advances in psychopharmacology. vol 5. issue 4. 2015-08-24. PMID:26301079. |
clozapine is the most effective treatment available for treatment-resistant schizophrenia; however, it is also associated with a large array of adverse effects that limits its tolerability. |
2015-08-24 |
2023-08-13 |
Not clear |