Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Bunta Yoshimura, Yuji Yada, Ryuhei So, Manabu Takaki, Norihito Yamad. The critical treatment window of clozapine in treatment-resistant schizophrenia: Secondary analysis of an observational study. Psychiatry research. vol 250. 2017-11-16. PMID:28142068. |
the critical treatment window of clozapine in treatment-resistant schizophrenia: secondary analysis of an observational study. |
2017-11-16 |
2023-08-13 |
Not clear |
Bunta Yoshimura, Yuji Yada, Ryuhei So, Manabu Takaki, Norihito Yamad. The critical treatment window of clozapine in treatment-resistant schizophrenia: Secondary analysis of an observational study. Psychiatry research. vol 250. 2017-11-16. PMID:28142068. |
previous studies have suggested that a delay in initiating clozapine is one of the predictors of outcomes in treatment-resistant schizophrenia (trs). |
2017-11-16 |
2023-08-13 |
Not clear |
Bunta Yoshimura, Yuji Yada, Ryuhei So, Manabu Takaki, Norihito Yamad. The critical treatment window of clozapine in treatment-resistant schizophrenia: Secondary analysis of an observational study. Psychiatry research. vol 250. 2017-11-16. PMID:28142068. |
clinicians should reduce the delay in initiating clozapine to less than 3 years to improve symptomatic outcomes in trs and to prevent clozapine-resistant schizophrenia. |
2017-11-16 |
2023-08-13 |
Not clear |
Jonathan G Leung, M Earth Hasassri, Jason N Barreto, Sarah Nelson, Robert J Morga. Characterization of Admission Types in Medically Hospitalized Patients Prescribed Clozapine. Psychosomatics. vol 58. issue 2. 2017-11-09. PMID:28153339. |
clozapine is the antipsychotic of choice for treatment-resistant schizophrenia; however, rigorous monitoring is required to prevent or detect adverse drug events that contribute to morbidity and mortality. |
2017-11-09 |
2023-08-13 |
Not clear |
Theresa Wimberley, Henrik Støvring, Holger J Sørensen, Henriette T Horsdal, James H MacCabe, Christiane Gass. Predictors of treatment resistance in patients with schizophrenia: a population-based cohort study. The lancet. Psychiatry. vol 3. issue 4. 2017-11-02. PMID:26922475. |
identification of patients at high risk of treatment-resistant schizophrenia at the time of schizophrenia diagnosis would be of great clinical benefit in minimising the delay to clozapine treatment in patients unlikely to respond to non-clozapine antipsychotics. |
2017-11-02 |
2023-08-13 |
Not clear |
Yumiko Akamine, Yuka Sugawara-Kikuchi, Tsukasa Uno, Tetsuo Shimizu, Masatomo Miur. Quantification of the steady-state plasma concentrations of clozapine and N-desmethylclozapine in Japanese patients with schizophrenia using a novel HPLC method and the effects of CYPs and ABC transporters polymorphisms. Annals of clinical biochemistry. vol 54. issue 6. 2017-10-30. PMID:27932669. |
quantification of the steady-state plasma concentrations of clozapine and n-desmethylclozapine in japanese patients with schizophrenia using a novel hplc method and the effects of cyps and abc transporters polymorphisms. |
2017-10-30 |
2023-08-13 |
human |
Lulu Jiang, Xuefei Wu, Shuo Wang, Shih-Heng Chen, Hui Zhou, Belinda Wilson, Chun-Yang Jin, Ru-Band Lu, Keqin Xie, Qingshan Wang, Jau-Shyong Hon. Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase. Journal of neuroinflammation. vol 13. issue 1. 2017-10-10. PMID:27184631. |
clozapine, an atypical antipsychotic medication, has been effectively used to treat refractory schizophrenia. |
2017-10-10 |
2023-08-13 |
Not clear |
Theresa Wimberley, James H MacCabe, Thomas M Laursen, Holger J Sørensen, Aske Astrup, Henriette T Horsdal, Christiane Gasse, Henrik Støvrin. Mortality and Self-Harm in Association With Clozapine in Treatment-Resistant Schizophrenia. The American journal of psychiatry. vol 174. issue 10. 2017-10-10. PMID:28750580. |
mortality and self-harm in association with clozapine in treatment-resistant schizophrenia. |
2017-10-10 |
2023-08-13 |
Not clear |
Theresa Wimberley, James H MacCabe, Thomas M Laursen, Holger J Sørensen, Aske Astrup, Henriette T Horsdal, Christiane Gasse, Henrik Støvrin. Mortality and Self-Harm in Association With Clozapine in Treatment-Resistant Schizophrenia. The American journal of psychiatry. vol 174. issue 10. 2017-10-10. PMID:28750580. |
this study evaluated rates of all-cause mortality and self-harm in association with clozapine treatment in individuals with treatment-resistant schizophrenia. |
2017-10-10 |
2023-08-13 |
Not clear |
Michał Wiciński, Mateusz M Węclewicz, Mateusz Miętkiewicz, Bartosz Malinowski, Elżbieta Grześk, Joanna Klonowsk. Potential Mechanisms of Hematological Adverse Drug Reactions in Patients Receiving Clozapine in Combination With Proton Pump Inhibitors. Journal of psychiatric practice. vol 23. issue 2. 2017-10-04. PMID:28291036. |
clozapine is a second-generation antipsychotic which has proven efficacy in treating the symptoms of schizophrenia. |
2017-10-04 |
2023-08-13 |
Not clear |
Yuan-Yuan Li, Yun-Shu Zhang, Jian Wang, Ke-Qing Li, Hong-Ying Wan. Optimal Treatment Strategies of Clozapine for Refractory Schizophrenia. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 38. issue 6. 2017-09-28. PMID:28065233. |
optimal treatment strategies of clozapine for refractory schizophrenia. |
2017-09-28 |
2023-08-13 |
Not clear |
Yuan-Yuan Li, Yun-Shu Zhang, Jian Wang, Ke-Qing Li, Hong-Ying Wan. Optimal Treatment Strategies of Clozapine for Refractory Schizophrenia. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 38. issue 6. 2017-09-28. PMID:28065233. |
objective to systematically evaluate the efficacy of clozapine combined with other antipsychotic drugs in the treatment of refractory schizophrenia. |
2017-09-28 |
2023-08-13 |
Not clear |
Yuan-Yuan Li, Yun-Shu Zhang, Jian Wang, Ke-Qing Li, Hong-Ying Wan. Optimal Treatment Strategies of Clozapine for Refractory Schizophrenia. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 38. issue 6. 2017-09-28. PMID:28065233. |
methods we searched medline, embase, and china biology medicine databases in both english and chinese for randomized controlled trials, quasi-randomization controlled trials, and clinical controlled trials concerning the combinations of clozapine with other antipsychotic drugs for refractory schizophrenia. |
2017-09-28 |
2023-08-13 |
Not clear |
Yuan-Yuan Li, Yun-Shu Zhang, Jian Wang, Ke-Qing Li, Hong-Ying Wan. Optimal Treatment Strategies of Clozapine for Refractory Schizophrenia. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 38. issue 6. 2017-09-28. PMID:28065233. |
conclusion reasonable combination of clozapine with other drugs may improve the therapeutic effectiveness and reduce adverse reactions and thus can be effectively used for treating refractory schizophrenia. |
2017-09-28 |
2023-08-13 |
Not clear |
L Simon, F Cazar. [Clozapine rechallenge after neutropenia in resistant schizophrenia: A review]. L'Encephale. vol 42. issue 4. 2017-09-20. PMID:27109327. |
[clozapine rechallenge after neutropenia in resistant schizophrenia: a review]. |
2017-09-20 |
2023-08-13 |
Not clear |
L Simon, F Cazar. [Clozapine rechallenge after neutropenia in resistant schizophrenia: A review]. L'Encephale. vol 42. issue 4. 2017-09-20. PMID:27109327. |
clozapine is an atypical antipsychotic known for its efficacy in refractory schizophrenia. |
2017-09-20 |
2023-08-13 |
Not clear |
M Jaafari, A Bout, I Rammouz, R Aalouan. [Reversible catatonia after the abrupt discontinuation of clozapine: Case report]. L'Encephale. vol 42. issue 6. 2017-09-20. PMID:27644914. |
in this paper, we report the case of a patient, aged 26, with schizophrenia who was admitted to psychiatric emergencies for catatonia, one week after abrupt discontinuation of clozapine. |
2017-09-20 |
2023-08-13 |
Not clear |
Dan Siskind, Lara McCartney, Romi Goldschlager, Steve Kisel. Clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis. The British journal of psychiatry : the journal of mental science. vol 209. issue 5. 2017-09-04. PMID:27388573. |
clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis. |
2017-09-04 |
2023-08-13 |
Not clear |
Magdalena Jiménez-Cornejo, Gonzalo Munizaga, David Aceitun. Does adding a second antipsychotic to clozapine improve clinical response in resistant schizophrenia? Medwave. vol 16. issue Suppl5. 2017-09-04. PMID:27922589. |
does adding a second antipsychotic to clozapine improve clinical response in resistant schizophrenia? |
2017-09-04 |
2023-08-13 |
Not clear |
Magdalena Jiménez-Cornejo, Gonzalo Munizaga, David Aceitun. Does adding a second antipsychotic to clozapine improve clinical response in resistant schizophrenia? Medwave. vol 16. issue Suppl5. 2017-09-04. PMID:27922589. |
clozapine constitutes the treatment of choice in patients with schizophrenia with persisting symptoms despite antipsychotics at adequate dose and treatment duration. |
2017-09-04 |
2023-08-13 |
Not clear |