| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Theresa Wimberley, James H MacCabe, Thomas M Laursen, Holger J Sørensen, Aske Astrup, Henriette T Horsdal, Christiane Gasse, Henrik Støvrin. Mortality and Self-Harm in Association With Clozapine in Treatment-Resistant Schizophrenia. The American journal of psychiatry. vol 174. issue 10. 2017-10-10. PMID:28750580. |
this study evaluated rates of all-cause mortality and self-harm in association with clozapine treatment in individuals with treatment-resistant schizophrenia. |
2017-10-10 |
2023-08-13 |
Not clear |
| Michał Wiciński, Mateusz M Węclewicz, Mateusz Miętkiewicz, Bartosz Malinowski, Elżbieta Grześk, Joanna Klonowsk. Potential Mechanisms of Hematological Adverse Drug Reactions in Patients Receiving Clozapine in Combination With Proton Pump Inhibitors. Journal of psychiatric practice. vol 23. issue 2. 2017-10-04. PMID:28291036. |
clozapine is a second-generation antipsychotic which has proven efficacy in treating the symptoms of schizophrenia. |
2017-10-04 |
2023-08-13 |
Not clear |
| Yuan-Yuan Li, Yun-Shu Zhang, Jian Wang, Ke-Qing Li, Hong-Ying Wan. Optimal Treatment Strategies of Clozapine for Refractory Schizophrenia. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 38. issue 6. 2017-09-28. PMID:28065233. |
optimal treatment strategies of clozapine for refractory schizophrenia. |
2017-09-28 |
2023-08-13 |
Not clear |
| Yuan-Yuan Li, Yun-Shu Zhang, Jian Wang, Ke-Qing Li, Hong-Ying Wan. Optimal Treatment Strategies of Clozapine for Refractory Schizophrenia. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 38. issue 6. 2017-09-28. PMID:28065233. |
objective to systematically evaluate the efficacy of clozapine combined with other antipsychotic drugs in the treatment of refractory schizophrenia. |
2017-09-28 |
2023-08-13 |
Not clear |
| Yuan-Yuan Li, Yun-Shu Zhang, Jian Wang, Ke-Qing Li, Hong-Ying Wan. Optimal Treatment Strategies of Clozapine for Refractory Schizophrenia. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 38. issue 6. 2017-09-28. PMID:28065233. |
methods we searched medline, embase, and china biology medicine databases in both english and chinese for randomized controlled trials, quasi-randomization controlled trials, and clinical controlled trials concerning the combinations of clozapine with other antipsychotic drugs for refractory schizophrenia. |
2017-09-28 |
2023-08-13 |
Not clear |
| Yuan-Yuan Li, Yun-Shu Zhang, Jian Wang, Ke-Qing Li, Hong-Ying Wan. Optimal Treatment Strategies of Clozapine for Refractory Schizophrenia. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 38. issue 6. 2017-09-28. PMID:28065233. |
conclusion reasonable combination of clozapine with other drugs may improve the therapeutic effectiveness and reduce adverse reactions and thus can be effectively used for treating refractory schizophrenia. |
2017-09-28 |
2023-08-13 |
Not clear |
| L Simon, F Cazar. [Clozapine rechallenge after neutropenia in resistant schizophrenia: A review]. L'Encephale. vol 42. issue 4. 2017-09-20. PMID:27109327. |
[clozapine rechallenge after neutropenia in resistant schizophrenia: a review]. |
2017-09-20 |
2023-08-13 |
Not clear |
| L Simon, F Cazar. [Clozapine rechallenge after neutropenia in resistant schizophrenia: A review]. L'Encephale. vol 42. issue 4. 2017-09-20. PMID:27109327. |
clozapine is an atypical antipsychotic known for its efficacy in refractory schizophrenia. |
2017-09-20 |
2023-08-13 |
Not clear |
| M Jaafari, A Bout, I Rammouz, R Aalouan. [Reversible catatonia after the abrupt discontinuation of clozapine: Case report]. L'Encephale. vol 42. issue 6. 2017-09-20. PMID:27644914. |
in this paper, we report the case of a patient, aged 26, with schizophrenia who was admitted to psychiatric emergencies for catatonia, one week after abrupt discontinuation of clozapine. |
2017-09-20 |
2023-08-13 |
Not clear |
| Dan Siskind, Lara McCartney, Romi Goldschlager, Steve Kisel. Clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis. The British journal of psychiatry : the journal of mental science. vol 209. issue 5. 2017-09-04. PMID:27388573. |
clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis. |
2017-09-04 |
2023-08-13 |
Not clear |
| Magdalena Jiménez-Cornejo, Gonzalo Munizaga, David Aceitun. Does adding a second antipsychotic to clozapine improve clinical response in resistant schizophrenia? Medwave. vol 16. issue Suppl5. 2017-09-04. PMID:27922589. |
does adding a second antipsychotic to clozapine improve clinical response in resistant schizophrenia? |
2017-09-04 |
2023-08-13 |
Not clear |
| Magdalena Jiménez-Cornejo, Gonzalo Munizaga, David Aceitun. Does adding a second antipsychotic to clozapine improve clinical response in resistant schizophrenia? Medwave. vol 16. issue Suppl5. 2017-09-04. PMID:27922589. |
clozapine constitutes the treatment of choice in patients with schizophrenia with persisting symptoms despite antipsychotics at adequate dose and treatment duration. |
2017-09-04 |
2023-08-13 |
Not clear |
| Magdalena Jiménez-Cornejo, Gonzalo Munizaga, David Aceitun. Does adding a second antipsychotic to clozapine improve clinical response in resistant schizophrenia? Medwave. vol 16. issue Suppl5. 2017-09-04. PMID:27922589. |
we concluded adding a second antipsychotic to clozapine in patients with refractory schizophrenia probably leads to little or no difference in clinical response, and increases adverse effects. |
2017-09-04 |
2023-08-13 |
Not clear |
| Madeleine Uys, Mohammed Shahid, Jukka Sallinen, Walter Dreyer, Marike Cockeran, Brian H Harve. The α2C-adrenoceptor antagonist, ORM-10921, has antipsychotic-like effects in social isolation reared rats and bolsters the response to haloperidol. Progress in neuro-psychopharmacology & biological psychiatry. vol 71. 2017-08-30. PMID:27381554. |
the beneficial effects of clozapine in refractory schizophrenia and associated cognitive deficits have, among others, been associated with its α2c-ar modulating activity. |
2017-08-30 |
2023-08-13 |
rat |
| Suvi Koskinen, Olli Kampman, Anssi Solismaa, Leo-Pekka Lyytikäinen, Niko Seppälä, Merja Viikki, Mari Hämäläinen, Eeva Moilanen, Nina Mononen, Terho Lehtimäki, Esa Leinone. INSIG2 polymorphism and weight gain, dyslipidemia and serum adiponectin in Finnish patients with schizophrenia treated with clozapine. Pharmacogenomics. vol 17. issue 18. 2017-08-30. PMID:27885961. |
insig2 polymorphism and weight gain, dyslipidemia and serum adiponectin in finnish patients with schizophrenia treated with clozapine. |
2017-08-30 |
2023-08-13 |
Not clear |
| Selvizhi Subramanian, Birgit A Völlm, Nick Huban. Clozapine dose for schizophrenia. The Cochrane database of systematic reviews. vol 6. 2017-08-16. PMID:28613395. |
clozapine dose for schizophrenia. |
2017-08-16 |
2023-08-13 |
Not clear |
| Selvizhi Subramanian, Birgit A Völlm, Nick Huban. Clozapine dose for schizophrenia. The Cochrane database of systematic reviews. vol 6. 2017-08-16. PMID:28613395. |
clozapine is useful in the treatment of schizophrenia and related disorders, particularly when other antipsychotic medications have failed. |
2017-08-16 |
2023-08-13 |
Not clear |
| Yuzuki Kanda, Miho Okada, Rina Ikarashi, Eri Morioka, Takashi Kondo, Masayuki Iked. Bimodal modulation of store-operated Ca Neuroscience letters. vol 635. 2017-08-15. PMID:27769892. |
bimodal modulation of store-operated ca clozapine (clz) and olanzapine (olz) are second generation (atypical) antipsychotics, used widely for treating schizophrenia and bipolar disorder. |
2017-08-15 |
2023-08-13 |
rat |
| C Zhang, Y Zhang, J Cai, M Chen, L Son. Complement 3 and metabolic syndrome induced by clozapine: a cross-sectional study and retrospective cohort analysis. The pharmacogenomics journal. vol 17. issue 1. 2017-07-31. PMID:26503818. |
we recruited 576 schizophrenia patients taking clozapine and measured the serum levels of fasting metabolic parameters. |
2017-07-31 |
2023-08-13 |
Not clear |
| Adam J Prus, Laura E Wise, Alan L Pehrson, Scott D Philibin, Benny Bang-Andersen, Jørn Arnt, Joseph H Porte. Discriminative stimulus properties of 1.25mg/kg clozapine in rats: Mediation by serotonin 5-HT2 and dopamine D4 receptors. Brain research. vol 1648. issue Pt A. 2017-07-26. PMID:27502027. |
the atypical antipsychotic drug clozapine remains one of most effective treatments for schizophrenia, given a lack of extrapyramidal side effects, improvements in negative symptoms, cognitive impairment, and in symptoms in treatment-resistant schizophrenia. |
2017-07-26 |
2023-08-13 |
rat |