| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matteo Marcatili, Fabio Marsoner, Armando D'Agostino, Thodoris Karnavas, Daniele Bottai, Silvio Scarone, Luciano Cont. Establishment of an induced pluripotent stem cell (iPSC) line from a patient with Clozapine-responder Schizophrenia. Stem cell research. vol 17. issue 3. 2018-01-22. PMID:27934596. |
this hipsc line represents a valuable tool to study the molecular, biochemical and electrophysiological properties of mature neuronal populations belonging to clozapine responder patients with a severe form of schizophrenia. |
2018-01-22 |
2023-08-13 |
Not clear |
| S E Legge, M L Hamshere, S Ripke, A F Pardinas, J I Goldstein, E Rees, A L Richards, G Leonenko, L F Jorskog, K D Chambert, D A Collier, G Genovese, I Giegling, P Holmans, A Jonasdottir, G Kirov, S A McCarroll, J H MacCabe, K Mantripragada, J L Moran, B M Neale, H Stefansson, D Rujescu, M J Daly, P F Sullivan, M J Owen, M C O'Donovan, J T R Walter. Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia. Molecular psychiatry. vol 22. issue 10. 2018-01-19. PMID:27400856. |
the antipsychotic clozapine is uniquely effective in the management of schizophrenia; however, its use is limited by its potential to induce agranulocytosis. |
2018-01-19 |
2023-08-13 |
human |
| Euitae Kim, Oliver D Howes, Mattia Veronese, Katherine Beck, Seongho Seo, Jin Woo Park, Jae Sung Lee, Yun-Sang Lee, Jun Soo Kwo. Presynaptic Dopamine Capacity in Patients with Treatment-Resistant Schizophrenia Taking Clozapine: An [ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 4. 2018-01-19. PMID:27857125. |
presynaptic dopamine capacity in patients with treatment-resistant schizophrenia taking clozapine: an [ some patients with schizophrenia show poor response to first-line antipsychotic treatments and this is termed treatment-resistant schizophrenia. |
2018-01-19 |
2023-08-13 |
human |
| Alp Üçok, Ugur Çıkrıkçılı, Ceylan Ergül, Öznur Tabak, Ada Salaj, Sercan Karabulut, Christoph U Correl. Correlates of Clozapine Use after a First Episode of Schizophrenia: Results From a Long-term Prospective Study. CNS drugs. vol 30. issue 10. 2018-01-17. PMID:27356920. |
correlates of clozapine use after a first episode of schizophrenia: results from a long-term prospective study. |
2018-01-17 |
2023-08-13 |
Not clear |
| Alp Üçok, Ugur Çıkrıkçılı, Ceylan Ergül, Öznur Tabak, Ada Salaj, Sercan Karabulut, Christoph U Correl. Correlates of Clozapine Use after a First Episode of Schizophrenia: Results From a Long-term Prospective Study. CNS drugs. vol 30. issue 10. 2018-01-17. PMID:27356920. |
earlier commencement of clozapine has been related to a better response in treatment-resistant schizophrenia. |
2018-01-17 |
2023-08-13 |
Not clear |
| Marise Wj Machielsen, Dick J Veltman, Wim van den Brink, Lieuwe de Haa. The effect of clozapine and risperidone on attentional bias in patients with schizophrenia and a cannabis use disorder: An fMRI study. Journal of psychopharmacology (Oxford, England). vol 28. issue 7. 2018-01-16. PMID:24646809. |
the effect of clozapine and risperidone on attentional bias in patients with schizophrenia and a cannabis use disorder: an fmri study. |
2018-01-16 |
2023-08-12 |
Not clear |
| Marise Wj Machielsen, Dick J Veltman, Wim van den Brink, Lieuwe de Haa. The effect of clozapine and risperidone on attentional bias in patients with schizophrenia and a cannabis use disorder: An fMRI study. Journal of psychopharmacology (Oxford, England). vol 28. issue 7. 2018-01-16. PMID:24646809. |
we compared the effects of clozapine and risperidone on attentional bias, subjective craving and associated regional brain activity in patients with schizophrenia and cud. |
2018-01-16 |
2023-08-12 |
Not clear |
| Marise Wj Machielsen, Dick J Veltman, Wim van den Brink, Lieuwe de Haa. The effect of clozapine and risperidone on attentional bias in patients with schizophrenia and a cannabis use disorder: An fMRI study. Journal of psychopharmacology (Oxford, England). vol 28. issue 7. 2018-01-16. PMID:24646809. |
these findings strongly suggest that clozapine may be a better treatment choice in patients with schizophrenia and cud than risperidone. |
2018-01-16 |
2023-08-12 |
Not clear |
| I Qurashi, J D Collins, I B Chaudhry, N Husai. Promising use of minocycline augmentation with clozapine in treatment-resistant schizophrenia. Journal of psychopharmacology (Oxford, England). vol 28. issue 7. 2018-01-16. PMID:24646811. |
promising use of minocycline augmentation with clozapine in treatment-resistant schizophrenia. |
2018-01-16 |
2023-08-12 |
Not clear |
| I Qurashi, J D Collins, I B Chaudhry, N Husai. Promising use of minocycline augmentation with clozapine in treatment-resistant schizophrenia. Journal of psychopharmacology (Oxford, England). vol 28. issue 7. 2018-01-16. PMID:24646811. |
treatment-resistant schizophrenia is a major health problem in the uk with the majority of patients treated with clozapine. |
2018-01-16 |
2023-08-12 |
Not clear |
| Alessandro Rimessi, Chiara Pavan, Elli Ioannidi, Federica Nigro, Claudia Morganti, Alberto Brugnoli, Francesco Longo, Chiara Gardin, Letizia Ferroni, Michele Morari, Vincenzo Vindigni, Barbara Zavan, Paolo Pinto. Protein Kinase C β: a New Target Therapy to Prevent the Long-Term Atypical Antipsychotic-Induced Weight Gain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 7. 2018-01-12. PMID:28128334. |
among them, clozapine is the most effective medication for treatment-resistant schizophrenia and is most helpful in controlling aggression and the suicidal behavior in schizophrenia and schizoaffective disorder. |
2018-01-12 |
2023-08-13 |
mouse |
| Ozhan Yalcin, Gizem Kaymak, Ayten Erdogan, Canan Tanidir, Gul Karacetin, Ali Guven Kilicoglu, Caner Mutlu, Hilal Adaletli, Hatice Gunes, Kayhan Bahali, Basak Ayik, Ozden Sukran Uner. A Retrospective Investigation of Clozapine Treatment in Autistic and Nonautistic Children and Adolescents in an Inpatient Clinic in Turkey. Journal of child and adolescent psychopharmacology. vol 26. issue 9. 2018-01-08. PMID:26771824. |
the aim of this retrospective study is to examine the clinical outcomes and safety of clozapine in children and adolescents with schizophrenia or other psychotic disorders/autism spectrum disorder (asd) or affective disorders. |
2018-01-08 |
2023-08-13 |
Not clear |
| Sophie E Legge, Marian Hamshere, Richard D Hayes, Johnny Downs, Michael C O'Donovan, Michael J Owen, James T R Walters, James H MacCab. Reasons for discontinuing clozapine: A cohort study of patients commencing treatment. Schizophrenia research. vol 174. issue 1-3. 2018-01-05. PMID:27211516. |
clozapine is uniquely effective in the management of treatment-resistant schizophrenia (trs). |
2018-01-05 |
2023-08-13 |
Not clear |
| Inti Qurashi, Simon Chu, Nusrat Husain, Richard J Drake, Imran Chaudhry, J F W Deaki. Glycopyrrolate in comparison to hyoscine hydrobromide and placebo in the treatment of hypersalivation induced by clozapine (GOTHIC1): study protocol for a randomised controlled feasibility study. Trials. vol 17. issue 1. 2018-01-05. PMID:27871302. |
clozapine is the only medication licensed for the treatment of resistant schizophrenia in the uk. |
2018-01-05 |
2023-08-13 |
Not clear |
| Vilte E Barakauskas, Annie Moradian, Alasdair M Barr, Clare L Beasley, Gorazd Rosoklija, J John Mann, Boro Ilievski, Aleksandar Stankov, Andrew J Dwork, Peter Falkai, Gregg B Morin, William G Hone. Quantitative mass spectrometry reveals changes in SNAP-25 isoforms in schizophrenia. Schizophrenia research. vol 177. issue 1-3. 2018-01-02. PMID:26971072. |
administration of haloperidol or clozapine to rats did not mimic the changes found in schizophrenia. |
2018-01-02 |
2023-08-13 |
rat |
| Takanobu Nakazawa, Masataka Kikuchi, Mitsuru Ishikawa, Hidenaga Yamamori, Kazuki Nagayasu, Takuya Matsumoto, Michiko Fujimoto, Yuka Yasuda, Mikiya Fujiwara, Shota Okada, Kensuke Matsumura, Atsushi Kasai, Atsuko Hayata-Takano, Norihito Shintani, Shusuke Numata, Kazuhiro Takuma, Wado Akamatsu, Hideyuki Okano, Akihiro Nakaya, Hitoshi Hashimoto, Ryota Hashimot. Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. Schizophrenia research. vol 181. 2018-01-02. PMID:28277309. |
differential gene expression profiles in neurons generated from lymphoblastoid b-cell line-derived ips cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. |
2018-01-02 |
2023-08-13 |
Not clear |
| Takanobu Nakazawa, Masataka Kikuchi, Mitsuru Ishikawa, Hidenaga Yamamori, Kazuki Nagayasu, Takuya Matsumoto, Michiko Fujimoto, Yuka Yasuda, Mikiya Fujiwara, Shota Okada, Kensuke Matsumura, Atsushi Kasai, Atsuko Hayata-Takano, Norihito Shintani, Shusuke Numata, Kazuhiro Takuma, Wado Akamatsu, Hideyuki Okano, Akihiro Nakaya, Hitoshi Hashimoto, Ryota Hashimot. Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. Schizophrenia research. vol 181. 2018-01-02. PMID:28277309. |
clozapine is the most effective antipsychotic drug for treatment-resistant schizophrenia; however, clozapine has rare but serious side-effects. |
2018-01-02 |
2023-08-13 |
Not clear |
| Takanobu Nakazawa, Masataka Kikuchi, Mitsuru Ishikawa, Hidenaga Yamamori, Kazuki Nagayasu, Takuya Matsumoto, Michiko Fujimoto, Yuka Yasuda, Mikiya Fujiwara, Shota Okada, Kensuke Matsumura, Atsushi Kasai, Atsuko Hayata-Takano, Norihito Shintani, Shusuke Numata, Kazuhiro Takuma, Wado Akamatsu, Hideyuki Okano, Akihiro Nakaya, Hitoshi Hashimoto, Ryota Hashimot. Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. Schizophrenia research. vol 181. 2018-01-02. PMID:28277309. |
these results, which contribute to the current understanding of the molecular mechanisms of clozapine action, establish a new strategy for the use of monozygotic twin studies in schizophrenia research. |
2018-01-02 |
2023-08-13 |
Not clear |
| J-P Klemettilä, O Kampman, A Solismaa, L-P Lyytikäinen, N Seppälä, M Viikki, M Hämäläinen, E Moilanen, N Mononen, T Lehtimäki, E Leinone. Association study of arcuate nucleus neuropeptide Y neuron receptor gene variation and serum NPY levels in clozapine treated patients with schizophrenia. European psychiatry : the journal of the Association of European Psychiatrists. vol 40. 2017-12-20. PMID:27837667. |
association study of arcuate nucleus neuropeptide y neuron receptor gene variation and serum npy levels in clozapine treated patients with schizophrenia. |
2017-12-20 |
2023-08-13 |
Not clear |
| Yusuke Nakata, Nobuhisa Kanahara, Hiroshi Kimura, Hiroyuki Watanabe, Masaomi Iy. Efficacy of clozapine on dopamine supersensitivity psychosis in schizophrenia. International clinical psychopharmacology. vol 32. issue 3. 2017-12-18. PMID:28067751. |
efficacy of clozapine on dopamine supersensitivity psychosis in schizophrenia. |
2017-12-18 |
2023-08-13 |
Not clear |