| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ishwary Damodaran, Koh Ong Hui, Amer Siddiq Amer Nordin, Anne Yee, Jesjeet Singh Gill, Benedict Francis, Fatin Liyana Azhar, Ahmad Hatim Sulaima. An Open-Label, Head to Head Comparison Study between Prucalopride and Lactulose for Clozapine Induced Constipation in Patients with Treatment Resistant Schizophrenia. Healthcare (Basel, Switzerland). vol 8. issue 4. 2020-12-26. PMID:33287162. |
male and female patients on clozapine between the age of 18-60 with an established diagnosis of treatment resistant schizophrenia with ≤2 spontaneous complete bowel movement per week were recruited in this study. |
2020-12-26 |
2023-08-13 |
Not clear |
| Xingqin Zhou, Gangming Cai, Shishi Mao, Dong Xu, Xijie Xu, Rongjun Zhang, Zhiwen Ya. Modulating NMDA receptors to treat MK-801-induced schizophrenic cognition deficit: effects of clozapine combining with PQQ treatment and possible mechanisms of action. BMC psychiatry. vol 20. issue 1. 2020-12-21. PMID:32143671. |
clozapine has remarkable efficacy on both negative and cognitive symptoms of schizophrenia due to its slight activation of nmda receptor. |
2020-12-21 |
2023-08-13 |
Not clear |
| Xingqin Zhou, Gangming Cai, Shishi Mao, Dong Xu, Xijie Xu, Rongjun Zhang, Zhiwen Ya. Modulating NMDA receptors to treat MK-801-induced schizophrenic cognition deficit: effects of clozapine combining with PQQ treatment and possible mechanisms of action. BMC psychiatry. vol 20. issue 1. 2020-12-21. PMID:32143671. |
the aim of this study was to enhance nmdar function and improve cognitive ability in schizophrenia by pqq combined with clozapine. |
2020-12-21 |
2023-08-13 |
Not clear |
| Xinyu Fang, Lingfang Yu, Dandan Wang, Yan Chen, Yewei Wang, Zenan Wu, Ruimei Liu, Juanjuan Ren, Wei Tang, Chen Zhan. Association Between SIRT1, Cytokines, and Metabolic Syndrome in Schizophrenia Patients With Olanzapine or Clozapine Monotherapy. Frontiers in psychiatry. vol 11. 2020-12-17. PMID:33324265. |
association between sirt1, cytokines, and metabolic syndrome in schizophrenia patients with olanzapine or clozapine monotherapy. |
2020-12-17 |
2023-08-13 |
Not clear |
| Edward Silva, Melanie Higgins, Barbara Hammer, Paul Stephenso. Clozapine rechallenge and initiation despite neutropenia- a practical, step-by-step guide. BMC psychiatry. vol 20. issue 1. 2020-12-15. PMID:32503471. |
clozapine remains the only drug treatment likely to benefit patients with treatment resistant schizophrenia. |
2020-12-15 |
2023-08-13 |
Not clear |
| Yağmur Kır, Bora Baskak, Adnan Kuşman, Damla Sayar-Akaslan, Fezile Özdemir, Nilay Sedes-Baskak, Halit Sinan Süzen, Zeynel Bara. The relationship between plasma levels of clozapine and N-desmethyclozapine as well as M1 receptor polymorphism with cognitive functioning and associated cortical activity in schizophrenia. Psychiatry research. Neuroimaging. vol 303. 2020-12-14. PMID:32593951. |
the relationship between plasma levels of clozapine and n-desmethyclozapine as well as m1 receptor polymorphism with cognitive functioning and associated cortical activity in schizophrenia. |
2020-12-14 |
2023-08-13 |
human |
| Yağmur Kır, Bora Baskak, Adnan Kuşman, Damla Sayar-Akaslan, Fezile Özdemir, Nilay Sedes-Baskak, Halit Sinan Süzen, Zeynel Bara. The relationship between plasma levels of clozapine and N-desmethyclozapine as well as M1 receptor polymorphism with cognitive functioning and associated cortical activity in schizophrenia. Psychiatry research. Neuroimaging. vol 303. 2020-12-14. PMID:32593951. |
studies that examined the effect of clozapine on cognitive functions in schizophrenia provided contradictory results. |
2020-12-14 |
2023-08-13 |
human |
| Yağmur Kır, Bora Baskak, Adnan Kuşman, Damla Sayar-Akaslan, Fezile Özdemir, Nilay Sedes-Baskak, Halit Sinan Süzen, Zeynel Bara. The relationship between plasma levels of clozapine and N-desmethyclozapine as well as M1 receptor polymorphism with cognitive functioning and associated cortical activity in schizophrenia. Psychiatry research. Neuroimaging. vol 303. 2020-12-14. PMID:32593951. |
we investigated the association of plasma clozapine (pclz), ndmc (pndmc) levels and the rs2067477 polymorphism with cognitive functions and cortical activity measured by functional near infrared spectroscopy during the n-back task in subjects with schizophrenia (n = 50) who are under antipsychotic monotherapy with clozapine. |
2020-12-14 |
2023-08-13 |
human |
| Tsuyoshi Okada, Jun Kumakura, Manabu Yasuda, Shiro Sud. Treatment-resistant schizophrenia successfully maintained with brexpiprazole following abrupt withdrawal of clozapine due to neutropenia. Asian journal of psychiatry. vol 47. 2020-12-10. PMID:31677398. |
treatment-resistant schizophrenia successfully maintained with brexpiprazole following abrupt withdrawal of clozapine due to neutropenia. |
2020-12-10 |
2023-08-13 |
Not clear |
| Matea Nikolac Perkovic, Marina Sagud, Maja Zivkovic, Suzana Uzun, Gordana Nedic Erjavec, Oliver Kozumplik, Dubravka Svob Strac, Ninoslav Mimica, Alma Mihaljevic Peles, Nela Piva. Catechol-O-methyltransferase rs4680 and rs4818 haplotype association with treatment response to olanzapine in patients with schizophrenia. Scientific reports. vol 10. issue 1. 2020-12-10. PMID:32572118. |
the study assessed the association of the comt rs4680 and rs4818 polymorphisms with therapeutic response to olanzapine, risperidone, clozapine or other antipsychotic medication after 8 weeks of monotherapy in patients with schizophrenia. |
2020-12-10 |
2023-08-13 |
Not clear |
| Matea Nikolac Perkovic, Marina Sagud, Maja Zivkovic, Suzana Uzun, Gordana Nedic Erjavec, Oliver Kozumplik, Dubravka Svob Strac, Ninoslav Mimica, Alma Mihaljevic Peles, Nela Piva. Catechol-O-methyltransferase rs4680 and rs4818 haplotype association with treatment response to olanzapine in patients with schizophrenia. Scientific reports. vol 10. issue 1. 2020-12-10. PMID:32572118. |
521 caucasian patients with schizophrenia received a monotherapy with olanzapine (10-20 mg/day; n = 190), risperidone (3-6 mg/day; n = 99), or clozapine (100-500 mg/day; n = 102). |
2020-12-10 |
2023-08-13 |
Not clear |
| Royun Park, Seoyoung Kim, Euitae Ki. Relationship of Change in Plasma Clozapine/N-desmethylclozapine Ratio with Cognitive Performance in Patients with Schizophrenia. Psychiatry investigation. vol 17. issue 11. 2020-12-10. PMID:33198433. |
the aim of this study is to determine whether clozapine has influence on cognitive performance in accordance with changes in the clozapine/ndmc in patients with schizophrenia. |
2020-12-10 |
2023-08-13 |
Not clear |
| Wenying Yi, Shenglin She, Jie Zhang, Haibo Wu, Yingjun Zheng, Yuping Nin. Clozapine Use in Patients with Early-Stage Schizophrenia in a Chinese Psychiatric Hospital. Neuropsychiatric disease and treatment. vol 16. 2020-12-07. PMID:33262597. |
clozapine use in patients with early-stage schizophrenia in a chinese psychiatric hospital. |
2020-12-07 |
2023-08-13 |
Not clear |
| Wenying Yi, Shenglin She, Jie Zhang, Haibo Wu, Yingjun Zheng, Yuping Nin. Clozapine Use in Patients with Early-Stage Schizophrenia in a Chinese Psychiatric Hospital. Neuropsychiatric disease and treatment. vol 16. 2020-12-07. PMID:33262597. |
previous studies suggest that clozapine is commonly underutilized and that its initiation is delayed in patients with first-episode schizophrenia. |
2020-12-07 |
2023-08-13 |
Not clear |
| Wenying Yi, Shenglin She, Jie Zhang, Haibo Wu, Yingjun Zheng, Yuping Nin. Clozapine Use in Patients with Early-Stage Schizophrenia in a Chinese Psychiatric Hospital. Neuropsychiatric disease and treatment. vol 16. 2020-12-07. PMID:33262597. |
knowledge regarding clozapine use among chinese patients with early-stage schizophrenia is limited. |
2020-12-07 |
2023-08-13 |
Not clear |
| Wenying Yi, Shenglin She, Jie Zhang, Haibo Wu, Yingjun Zheng, Yuping Nin. Clozapine Use in Patients with Early-Stage Schizophrenia in a Chinese Psychiatric Hospital. Neuropsychiatric disease and treatment. vol 16. 2020-12-07. PMID:33262597. |
the aim of the present study was to investigate the point prevalence of and patterns and factors associated with clozapine use in patients with early-stage schizophrenia discharged from a psychiatric hospital in china. |
2020-12-07 |
2023-08-13 |
Not clear |
| Ana Miruna Dragoi, Ioana Radulescu, Bogdana Adriana Năsui, Anca Lucia Pop, Valentin Nicolae Varlas, Simona Trif. Clozapine: An Updated Overview of Pharmacogenetic Biomarkers, Risks, and Safety-Particularities in the Context of COVID-19. Brain sciences. vol 10. issue 11. 2020-12-01. PMID:33187329. |
clozapine (clz) use is precarious due to its neurological, cardiovascular, and hematological side effects; however, it is the gold standard in therapy-resistant schizophrenia (trs) in adults and is underused. |
2020-12-01 |
2023-08-13 |
Not clear |
| Jing Qiu, Hongxia Gong, Bixin Wang, Weiguo Gu, Lei Wang, Miaomiao Gu, Yuan Zhang, Xiangdong D. The use of clozapine is protective for low bone mineral density induced by prolactin-raising antipsychotics in inpatients with schizophrenia. Archives of osteoporosis. vol 15. issue 1. 2020-11-30. PMID:32601884. |
the use of clozapine is protective for low bone mineral density induced by prolactin-raising antipsychotics in inpatients with schizophrenia. |
2020-11-30 |
2023-08-13 |
Not clear |
| Katharina Robichon, Vimal Patel, Bronwen Connor, Anne Camille La Flamm. Clozapine reduces infiltration into the CNS by targeting migration in experimental autoimmune encephalomyelitis. Journal of neuroinflammation. vol 17. issue 1. 2020-11-23. PMID:32050980. |
atypical antipsychotic agents, such as clozapine, are used to treat schizophrenia and other psychiatric disorders by a mechanism that is believed to involve modulating the immune system. |
2020-11-23 |
2023-08-13 |
Not clear |
| Parita Shah, Yusuke Iwata, Eric E Brown, Julia Kim, Marcos Sanches, Hiroyoshi Takeuchi, Shinichiro Nakajima, Margaret Hahn, Gary Remington, Philip Gerretsen, Ariel Graff-Guerrer. Clozapine response trajectories and predictors of non-response in treatment-resistant schizophrenia: a chart review study. European archives of psychiatry and clinical neuroscience. vol 270. issue 1. 2020-11-06. PMID:31428862. |
clozapine response trajectories and predictors of non-response in treatment-resistant schizophrenia: a chart review study. |
2020-11-06 |
2023-08-13 |
Not clear |