| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ebenezer Oloyede, Olubanke Dzahini, Eromona Whiskey, David Taylo. Clozapine and Norclozapine Plasma Levels in Patients Switched Between Different Liquid Formulations. Therapeutic drug monitoring. vol 42. issue 3. 2021-05-05. PMID:31652191. |
clozapine is the drug of choice for treatment-resistant schizophrenia. |
2021-05-05 |
2023-08-13 |
Not clear |
| David Kitchen, Alex Till, Panchu Xavie. Routine clozapine assay monitoring to improve the management of treatment-resistant schizophrenia. BJPsych bulletin. 2021-04-29. PMID:33910673. |
routine clozapine assay monitoring to improve the management of treatment-resistant schizophrenia. |
2021-04-29 |
2023-08-13 |
Not clear |
| Jurjen J Luykx, Noraly Stam, Antti Tanskanen, Jari Tiihonen, Heidi Taipal. In the aftermath of clozapine discontinuation: comparative effectiveness and safety of antipsychotics in patients with schizophrenia who discontinue clozapine. The British journal of psychiatry : the journal of mental science. vol 217. issue 3. 2021-04-27. PMID:31910911. |
in the aftermath of clozapine discontinuation: comparative effectiveness and safety of antipsychotics in patients with schizophrenia who discontinue clozapine. |
2021-04-27 |
2023-08-13 |
Not clear |
| J Leijala, O Kampman, J Suvisaari, S Eskeline. Daily functioning and symptom factors contributing to attitudes toward antipsychotic treatment and treatment adherence in outpatients with schizophrenia spectrum disorders. BMC psychiatry. vol 21. issue 1. 2021-04-26. PMID:33441112. |
this study investigated how schizophrenia core symptoms and daily functioning affect treatment adherence and attitudes toward antipsychotic medication and to compare patients using clozapine or other antipsychotics. |
2021-04-26 |
2023-08-13 |
Not clear |
| Naomichi Okamoto, Yuki Konishi, Hirofumi Tesen, Atsuko Ikenouchi, Reiji Yoshimur. A Low Clozapine Dose Improved Refractory Tardive Dystonia without Exacerbating Psychiatric Symptoms: A Case Report. International medical case reports journal. vol 14. 2021-04-24. PMID:33889030. |
clozapine is recommended for patients with schizophrenia and tardive dystonia (td); however, the appropriate dose remains unclear. |
2021-04-24 |
2023-08-13 |
Not clear |
| Naomichi Okamoto, Yuki Konishi, Hirofumi Tesen, Atsuko Ikenouchi, Reiji Yoshimur. A Low Clozapine Dose Improved Refractory Tardive Dystonia without Exacerbating Psychiatric Symptoms: A Case Report. International medical case reports journal. vol 14. 2021-04-24. PMID:33889030. |
herein, we report on a 41-year-old female with schizophrenia and td who was treated with a low clozapine dose. |
2021-04-24 |
2023-08-13 |
Not clear |
| Joomi Lee, Min-Gul Kim, Hyeon-Cheol Jeong, Kwang-Hee Shi. Physiologically-based pharmacokinetic model for clozapine in Korean patients with schizophrenia. Translational and clinical pharmacology. vol 29. issue 1. 2021-04-16. PMID:33854999. |
physiologically-based pharmacokinetic model for clozapine in korean patients with schizophrenia. |
2021-04-16 |
2023-08-13 |
Not clear |
| Joomi Lee, Min-Gul Kim, Hyeon-Cheol Jeong, Kwang-Hee Shi. Physiologically-based pharmacokinetic model for clozapine in Korean patients with schizophrenia. Translational and clinical pharmacology. vol 29. issue 1. 2021-04-16. PMID:33854999. |
clozapine has been used as a treatment of schizophrenia. |
2021-04-16 |
2023-08-13 |
Not clear |
| Joomi Lee, Min-Gul Kim, Hyeon-Cheol Jeong, Kwang-Hee Shi. Physiologically-based pharmacokinetic model for clozapine in Korean patients with schizophrenia. Translational and clinical pharmacology. vol 29. issue 1. 2021-04-16. PMID:33854999. |
this study aimed to develop a pbpk m&s of clozapine in korean patients with schizophrenia. |
2021-04-16 |
2023-08-13 |
Not clear |
| Miquel Bioque, Eduard Parellada, Clemente García-Rizo, Sílvia Amoretti, Adriana Fortea, Giovanni Oriolo, Pol Palau, Ester Boix-Quintana, Gemma Safont, Miquel Bernard. Clozapine and paliperidone palmitate antipsychotic combination in treatment-resistant schizophrenia and other psychotic disorders: A retrospective 6-month mirror-image study. European psychiatry : the journal of the Association of European Psychiatrists. vol 63. issue 1. 2021-04-13. PMID:32669145. |
clozapine and paliperidone palmitate antipsychotic combination in treatment-resistant schizophrenia and other psychotic disorders: a retrospective 6-month mirror-image study. |
2021-04-13 |
2023-08-13 |
Not clear |
| Sylwia Łukasiewic. Development of a New Polymeric Nanocarrier Dedicated to Controlled Clozapine Delivery at the Dopamine D Polymers. vol 13. issue 7. 2021-04-13. PMID:33805130. |
development of a new polymeric nanocarrier dedicated to controlled clozapine delivery at the dopamine d clozapine, the second generation antipsychotic drug, is one of the prominent compounds used for treatment of schizophrenia. |
2021-04-13 |
2023-08-13 |
Not clear |
| Sylwia Łukasiewic. Development of a New Polymeric Nanocarrier Dedicated to Controlled Clozapine Delivery at the Dopamine D Polymers. vol 13. issue 7. 2021-04-13. PMID:33805130. |
nevertheless, clozapine still remains the first-choice drug for the situation of drug-resistance schizophrenia. |
2021-04-13 |
2023-08-13 |
Not clear |
| Stefania Bonaccorso, Angelo Ricciardi, Sophie Ouabbou, Christos Theleritis, Arabella Ross-Michaelides, Antonio Metastasio, Neil Stewart, Marwa Mohammed, Fabrizio Schifan. Clozapine, neutropenia and Covid-19: should clinicians be concerned? 3 months report. Brain, behavior, & immunity - health. vol 13. 2021-04-06. PMID:33527097. |
clozapine is among the most effective antipsychotics used for treatment resistant schizophrenia. |
2021-04-06 |
2023-08-13 |
Not clear |
| Jessica Spokes, Samantha Hollingworth, Karl Winckel, Steve Kisely, Andrea Baker, Peter Cosgrove, Dan Siskin. Metformin reduces 12-month change in body weight among people newly commenced on clozapine: a retrospective naturalistic cohort study. Therapeutic advances in psychopharmacology. vol 11. 2021-04-03. PMID:33796266. |
as clozapine remains the most effective antipsychotic for treatment-resistant schizophrenia (trs), identifying treatments to ameliorate clozapine-induced weight gain (ciwg) is urgently needed to reduce this morality gap. |
2021-04-03 |
2023-08-13 |
Not clear |
| Ádám Menus, Ádám Kiss, Katalin Tóth, Dávid Sirok, Máté Déri, Ferenc Fekete, Gábor Csukly, Katalin Monostor. Association of clozapine-related metabolic disturbances with CYP3A4 expression in patients with schizophrenia. Scientific reports. vol 10. issue 1. 2021-03-29. PMID:33277605. |
clozapine is effective in treatment-resistant schizophrenia; however, adverse effects often result in discontinuation of clozapine therapy. |
2021-03-29 |
2023-08-13 |
Not clear |
| Ádám Menus, Ádám Kiss, Katalin Tóth, Dávid Sirok, Máté Déri, Ferenc Fekete, Gábor Csukly, Katalin Monostor. Association of clozapine-related metabolic disturbances with CYP3A4 expression in patients with schizophrenia. Scientific reports. vol 10. issue 1. 2021-03-29. PMID:33277605. |
in patients with schizophrenia (n = 96), development of clozapine concentration-dependent metabolic side-effects was found to be associated with pharmacokinetic variability related to cyp3a4 but not to cyp1a2 expression. |
2021-03-29 |
2023-08-13 |
Not clear |
| Dian-Jeng Li, Ching-Hua Lin, Cheng-Chung Che. Factors impeding switching from clozapine to paliperidone among patients with chronic schizophrenia-A retrospective cohort study. Experimental and clinical psychopharmacology. 2021-03-29. PMID:33779196. |
the present study aimed to investigate the predictors for failed switching from clozapine to paliperidone (fscp) among patients with chronic schizophrenia. |
2021-03-29 |
2023-08-13 |
human |
| Dian-Jeng Li, Ching-Hua Lin, Cheng-Chung Che. Factors impeding switching from clozapine to paliperidone among patients with chronic schizophrenia-A retrospective cohort study. Experimental and clinical psychopharmacology. 2021-03-29. PMID:33779196. |
this 9-year (january 2010-december 2018) retrospective study included 78 individuals with schizophrenia who wished to switch from clozapine to paliperidone and resided in a nursing home in taiwan. |
2021-03-29 |
2023-08-13 |
human |
| Rakesh Kumar, Arvind Sharma, Navneet Kaur, Anand Singh, Manik Chhabra, Rishabh Sharm. A case report on clozapine-induced ventricular ectopics: a fatal adverse drug reaction. Journal of basic and clinical physiology and pharmacology. vol 31. issue 3. 2021-03-26. PMID:32304306. |
background clozapine is one of the most efficacious antipsychotic drug used for the treatment-resistant schizophrenia; it is sometimes associated with serious adverse reactions like agranulocytosis, myocarditis, cardiac rhythm disturbances, etc. |
2021-03-26 |
2023-08-13 |
Not clear |
| Katsunori Toyoda, Takeo Hata, Shigeru Yamauchi, Shinya Kinoshita, Masami Nishihara, Kazuhisa Uchiyama, Ken Inada, Tetsufumi Kanazaw. Clozapine Is Better Tolerated in Younger Patients: Risk Factors for Discontinuation from a Nationwide Database in Japan. Psychiatry investigation. vol 18. issue 2. 2021-03-25. PMID:33460532. |
the effectiveness of clozapine is clearly superior to other antipsychotics in the treatment of refractory schizophrenia. |
2021-03-25 |
2023-08-13 |
Not clear |