| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juan Andrés Martínez-Andrés, Juan Antonio García-Carmon. Switching from clozapine to paliperidone palmitate-3-monthly improved obesity, hyperglycemia and dyslipidemia lowering antipsychotic dose equivalents in a treatment-resistant schizophrenia cohort. International clinical psychopharmacology. vol 35. issue 3. 2021-01-13. PMID:31851035. |
more studies are needed to truly establish the role of pp3m in treatment-resistant schizophrenia and should be compared against clozapine by using clinical trials. |
2021-01-13 |
2023-08-13 |
Not clear |
| Sandeep Grover, Meha Verma, Subho Chakrabart. Safety of Use of Clozapine in Patients With Schizophrenia With Comorbid Diabetes Mellitus. Journal of clinical psychopharmacology. vol 40. issue 3. 2021-01-13. PMID:32195772. |
safety of use of clozapine in patients with schizophrenia with comorbid diabetes mellitus. |
2021-01-13 |
2023-08-13 |
Not clear |
| Sandeep Grover, Meha Verma, Subho Chakrabart. Safety of Use of Clozapine in Patients With Schizophrenia With Comorbid Diabetes Mellitus. Journal of clinical psychopharmacology. vol 40. issue 3. 2021-01-13. PMID:32195772. |
to evaluate the outcome of diabetes mellitus among patients of schizophrenia who had diabetes mellitus before starting clozapine. |
2021-01-13 |
2023-08-13 |
Not clear |
| Herbert Y Meltzer, Daniel B Share, Karu Jayathilake, Ronald M Salomon, Myung A Le. Lurasidone Improves Psychopathology and Cognition in Treatment-Resistant Schizophrenia. Journal of clinical psychopharmacology. vol 40. issue 3. 2021-01-13. PMID:32332459. |
in addition to clozapine, other atypical antipsychotic drugs pharmacologically similar to clozapine, for example, olanzapine, risperidone, and melperone, are also effective in a similar proportion of treatment-resistant schizophrenia (trs) patients, ~40%. |
2021-01-13 |
2023-08-13 |
Not clear |
| Maxim Kuzin, Benjamin Bochon, Efstratios Vagiaris, Gerhard Dammann, Gerhard Gründer, Michael Paulzen, Georgios Schoretsaniti. Changes in Clozapine Bioavailability in a Percutaneous Endoscopic Gastrostomy-Fed Patient With Treatment-Resistant Schizophrenia. Journal of clinical psychopharmacology. vol 40. issue 3. 2021-01-13. PMID:32332469. |
changes in clozapine bioavailability in a percutaneous endoscopic gastrostomy-fed patient with treatment-resistant schizophrenia. |
2021-01-13 |
2023-08-13 |
Not clear |
| Naveen M, Amol N Patil, Smita Pattanaik, Anit Kaur, Dibyajyoti Banerjee, Sandeep Grove. ABCB1 and DRD3 polymorphism as a response predicting biomarker and tool for pharmacogenetically guided clozapine dosing in Asian Indian treatment resistant schizophrenia patients. Asian journal of psychiatry. vol 48. 2021-01-11. PMID:31896438. |
abcb1 and drd3 polymorphism as a response predicting biomarker and tool for pharmacogenetically guided clozapine dosing in asian indian treatment resistant schizophrenia patients. |
2021-01-11 |
2023-08-13 |
Not clear |
| Naveen M, Amol N Patil, Smita Pattanaik, Anit Kaur, Dibyajyoti Banerjee, Sandeep Grove. ABCB1 and DRD3 polymorphism as a response predicting biomarker and tool for pharmacogenetically guided clozapine dosing in Asian Indian treatment resistant schizophrenia patients. Asian journal of psychiatry. vol 48. 2021-01-11. PMID:31896438. |
to investigate association of two single nucleotide polymorphisms (snps) abcb1(rs1045462) and drd3(rs6280) with clozapine response and the dose in treatment resistant schizophrenia (trs) patients. |
2021-01-11 |
2023-08-13 |
Not clear |
| J Y K Poon, D Y Y Tang, B W M Siu, S H Lu. Elevated Clozapine Level Following Acute Infection in a Patient with Schizophrenia: a Case Report. East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan. vol 30. issue 4. 2021-01-11. PMID:33349619. |
elevated clozapine level following acute infection in a patient with schizophrenia: a case report. |
2021-01-11 |
2023-08-13 |
Not clear |
| J Y K Poon, D Y Y Tang, B W M Siu, S H Lu. Elevated Clozapine Level Following Acute Infection in a Patient with Schizophrenia: a Case Report. East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan. vol 30. issue 4. 2021-01-11. PMID:33349619. |
we describe a 58-year-old chinese man with schizophrenia who presented with an elevated clozapine level suspected to be related to acute infection. |
2021-01-11 |
2023-08-13 |
Not clear |
| Mehran Zarghami, Seyed Davood Hoseini, Arash Kazemi, Forouzan Elyas. Concurrent Hepatotoxicity and Neutropenia Induced by Clozapine. Archives of Iranian medicine. vol 23. issue 2. 2021-01-06. PMID:32061077. |
clozapine is known as one of the atypical antipsychotics which is placed in the second line of medical treatment for schizophrenia due to its hematologic complications. |
2021-01-06 |
2023-08-13 |
Not clear |
| Mehran Zarghami, Seyed Davood Hoseini, Arash Kazemi, Forouzan Elyas. Concurrent Hepatotoxicity and Neutropenia Induced by Clozapine. Archives of Iranian medicine. vol 23. issue 2. 2021-01-06. PMID:32061077. |
the patient was a 58-year-old man who started taking clozapine for the first time in march 2017, about seven weeks before his recent admission, because of a history of treatment-resistant schizophrenia. |
2021-01-06 |
2023-08-13 |
Not clear |
| T Scott Strou. Clozapine and Evidence-Based Psychopharmacology for Schizophrenia. JAMA psychiatry. vol 76. issue 10. 2021-01-04. PMID:31365031. |
clozapine and evidence-based psychopharmacology for schizophrenia. |
2021-01-04 |
2023-08-13 |
Not clear |
| Giuseppe Caruso, Margherita Grasso, Annamaria Fidilio, Fabio Tascedda, Filippo Drago, Filippo Carac. Antioxidant Properties of Second-Generation Antipsychotics: Focus on Microglia. Pharmaceuticals (Basel, Switzerland). vol 13. issue 12. 2020-12-29. PMID:33322693. |
opposite to haloperidol, second-generation antipsychotics (or atypical antipsychotics) such as risperidone, clozapine, and olanzapine exert a strong antioxidant activity in experimental models of schizophrenia by rescuing the antioxidant system, with an increase in superoxide dismutase and glutathione (gsh) serum levels. |
2020-12-29 |
2023-08-13 |
Not clear |
| Yuya Mizuno, Robert A McCutcheon, Stefan P Brugger, Oliver D Howe. Heterogeneity and efficacy of antipsychotic treatment for schizophrenia with or without treatment resistance: a meta-analysis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 4. 2020-12-28. PMID:31766049. |
two important clinical questions are whether there is a subtype of schizophrenia which responds differently to clozapine relative to other antipsychotics, and whether greater efficacy of clozapine is dependent on the degree of treatment-resistance. |
2020-12-28 |
2023-08-13 |
Not clear |
| Yuya Mizuno, Robert A McCutcheon, Stefan P Brugger, Oliver D Howe. Heterogeneity and efficacy of antipsychotic treatment for schizophrenia with or without treatment resistance: a meta-analysis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 4. 2020-12-28. PMID:31766049. |
the authors address this by examining both variability and magnitude of response in patients treated with clozapine and other antipsychotics for both treatment-resistant schizophrenia (trs) and non-resistant schizophrenia. |
2020-12-28 |
2023-08-13 |
Not clear |
| Yuya Mizuno, Robert A McCutcheon, Stefan P Brugger, Oliver D Howe. Heterogeneity and efficacy of antipsychotic treatment for schizophrenia with or without treatment resistance: a meta-analysis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 4. 2020-12-28. PMID:31766049. |
double-blind randomised controlled trials comparing clozapine with other antipsychotics in patients with schizophrenia were identified using five databases. |
2020-12-28 |
2023-08-13 |
Not clear |
| Yuya Mizuno, Robert A McCutcheon, Stefan P Brugger, Oliver D Howe. Heterogeneity and efficacy of antipsychotic treatment for schizophrenia with or without treatment resistance: a meta-analysis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 4. 2020-12-28. PMID:31766049. |
these findings do not support a subtype of schizophrenia which responds specifically to clozapine. |
2020-12-28 |
2023-08-13 |
Not clear |
| Yuya Mizuno, Robert A McCutcheon, Stefan P Brugger, Oliver D Howe. Heterogeneity and efficacy of antipsychotic treatment for schizophrenia with or without treatment resistance: a meta-analysis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 4. 2020-12-28. PMID:31766049. |
clozapine is more effective than other antipsychotics irrespective of treatment-resistance, arguing for its use more generally in schizophrenia. |
2020-12-28 |
2023-08-13 |
Not clear |
| Ishwary Damodaran, Koh Ong Hui, Amer Siddiq Amer Nordin, Anne Yee, Jesjeet Singh Gill, Benedict Francis, Fatin Liyana Azhar, Ahmad Hatim Sulaima. An Open-Label, Head to Head Comparison Study between Prucalopride and Lactulose for Clozapine Induced Constipation in Patients with Treatment Resistant Schizophrenia. Healthcare (Basel, Switzerland). vol 8. issue 4. 2020-12-26. PMID:33287162. |
an open-label, head to head comparison study between prucalopride and lactulose for clozapine induced constipation in patients with treatment resistant schizophrenia. |
2020-12-26 |
2023-08-13 |
Not clear |
| Ishwary Damodaran, Koh Ong Hui, Amer Siddiq Amer Nordin, Anne Yee, Jesjeet Singh Gill, Benedict Francis, Fatin Liyana Azhar, Ahmad Hatim Sulaima. An Open-Label, Head to Head Comparison Study between Prucalopride and Lactulose for Clozapine Induced Constipation in Patients with Treatment Resistant Schizophrenia. Healthcare (Basel, Switzerland). vol 8. issue 4. 2020-12-26. PMID:33287162. |
clozapine remains as the gold standard for the management of treatment resistant schizophrenia. |
2020-12-26 |
2023-08-13 |
Not clear |