All Relations between Schizophrenia and Clozapine

Publication Sentence Publish Date Extraction Date Species
Geng-Ruei Chang, Hsien-Yueh Liu, Wei-Cheng Yang, Chao-Min Wang, Ching-Fen Wu, Jen-Wei Lin, Wei-Li Lin, Yu-Chen Wang, Tzu-Chun Lin, Huei-Jyuan Liao, Po-Hsun Hou, Chee-Hong Chan, Chuen-Fu Li. Clozapine Worsens Glucose Intolerance, Nonalcoholic Fatty Liver Disease, Kidney Damage, and Retinal Injury and Increases Renal Reactive Oxygen Species Production and Chromium Loss in Obese Mice. International journal of molecular sciences. vol 22. issue 13. 2021-07-23. PMID:34206460. clozapine is widely employed in the treatment of schizophrenia. 2021-07-23 2023-08-13 mouse
Mariko Tsukiji, Tsuyoshi Sasaki, Yusuke Nakata, Kiyomitsu Ota, Tsutomu Aoki, Koichiro Hara, Takashi Mamada, Jun Nakane, Masanobu Kogure, Ryota Seki, Keita Idemoto, Tasuku Hashimoto, Hiraki Koishikawa, Toshihiro Moriyama, Takaaki Suzuki, Nobuhisa Kanahara, Itsuko Ishii, Masaomi Iyo, Tomihisa Niits. Risk factors for early-phase clozapine discontinuation: A nested case-control study. Asian journal of psychiatry. vol 62. 2021-07-21. PMID:34216977. safe and efficient methods for introducing clozapine to patients with treatment-resistant schizophrenia (trs) are needed. 2021-07-21 2023-08-13 Not clear
Elias Ghossoub, Amanie Salem, Susan Minchin, Davinder Hayreh, William J Newma. A Retrospective Review of the Use of Clozapine in Restoration of Competency to Stand Trial. The journal of the American Academy of Psychiatry and the Law. vol 49. issue 1. 2021-07-19. PMID:33246989. clozapine has been shown to be superior to other antipsychotic medications in treatment-resistant schizophrenia. 2021-07-19 2023-08-13 Not clear
Jianhua Chen, Ping Yang, Qian Zhang, Ruirui Chen, Peng Wang, Benxiu Liu, Wensheng Sun, Xuemin Jian, Siying Xiang, Juan Zhou, Ningning Li, Ke Wang, Chengwen Gao, Yanqin Wen, Chuanhong Wu, Jinmai Zhang, Yalin Zhao, Qiangzhen Yang, Meihang Li, Robert Stewart, Yuanchao Sun, Dun Pan, Yujuan Niu, Zhuo Wang, Yifeng Xu, Xingwang Li, Lin He, Zhiqiang Li, Yongyong Sh. Genetic risk of clozapine-induced leukopenia and neutropenia: a genome-wide association study. Translational psychiatry. vol 11. issue 1. 2021-07-14. PMID:34083506. clozapine is considered to be the most effective antipsychotic medication for schizophrenia. 2021-07-14 2023-08-13 Not clear
Henrik Maagensen, Julie R Larsen, Niklas R Jørgensen, Anders Fink-Jensen, Tina Vilsbøl. Liraglutide does not change bone turnover in clozapine- and olanzapine-treated schizophrenia overweight patients with prediabetes - randomized controlled trial. Psychiatry research. vol 296. 2021-07-13. PMID:33373806. as liraglutide has been proposed to affect bone metabolism, we evaluated the effect of liraglutide on bone turnover markers (btm) in patients with prediabetes and schizophrenia treated with olanzapine or clozapine. 2021-07-13 2023-08-13 Not clear
Gamze Gürcan, Şevin Hun Şenol, A Elif Anıl Yağcıoğlu, Aygün Ertuğru. Clinical risk factors, phenomenology and the impact of clozapine induced obsessive compulsive symptoms. Psychiatry research. vol 296. 2021-07-13. PMID:33465593. the aim of this study was to investigate the clinical risk factors, phenomenology and the impact of clozapine induced obsessive-compulsive symptoms (ocs) in patients with schizophrenia. 2021-07-13 2023-08-13 Not clear
R Jones, J H MacCabe, M J Price, X Liu, R Upthegrov. Effect of age on the relative efficacy of clozapine in schizophrenia. Acta psychiatrica Scandinavica. vol 142. issue 2. 2021-07-12. PMID:31977065. effect of age on the relative efficacy of clozapine in schizophrenia. 2021-07-12 2023-08-13 Not clear
H Verdoux, C Quile. Educational needs and psychoeducation interventions in clozapine users: a narrative review. Acta psychiatrica Scandinavica. vol 142. issue 2. 2021-07-12. PMID:32266962. increasing users' knowledge about the expected benefits and risks of clozapine may contribute to the initiation and maintenance of clozapine in persons with treatment-resistant schizophrenia (trs). 2021-07-12 2023-08-13 Not clear
H Takeuchi, C Borlido, M Sanches, C Teo, L Harber, O Agid, G Remingto. Adherence to clozapine vs. other antipsychotics in schizophrenia. Acta psychiatrica Scandinavica. vol 142. issue 2. 2021-07-12. PMID:32627168. adherence to clozapine vs. other antipsychotics in schizophrenia. 2021-07-12 2023-08-13 Not clear
Emma Wellesley Wesley, India Patel, Giouliana Kadra-Scalzo, Megan Pritchard, Hitesh Shetty, Matthew Broadbent, Aviv Segev, Rashmi Patel, Johnny Downs, James H MacCabe, Richard D Hayes, Daniela Fonseca de Freita. Gender disparities in clozapine prescription in a cohort of treatment-resistant schizophrenia in the South London and Maudsley case register. Schizophrenia research. vol 232. 2021-07-12. PMID:34022618. gender disparities in clozapine prescription in a cohort of treatment-resistant schizophrenia in the south london and maudsley case register. 2021-07-12 2023-08-13 Not clear
Emma Wellesley Wesley, India Patel, Giouliana Kadra-Scalzo, Megan Pritchard, Hitesh Shetty, Matthew Broadbent, Aviv Segev, Rashmi Patel, Johnny Downs, James H MacCabe, Richard D Hayes, Daniela Fonseca de Freita. Gender disparities in clozapine prescription in a cohort of treatment-resistant schizophrenia in the South London and Maudsley case register. Schizophrenia research. vol 232. 2021-07-12. PMID:34022618. there has been little research into whether clozapine prescription, the first-line treatment for treatment-resistant schizophrenia (trs), is affected by patient gender. 2021-07-12 2023-08-13 Not clear
Zoe Harrison, Owen Haeney, William Brereto. Augmentation of Antipsychotic Medications with Low-Dose Clozapine in Treatment-Resistant Schizophrenia-Case Reports and Discussion. Case reports in psychiatry. vol 2021. 2021-07-10. PMID:34239749. treatment resistance in schizophrenia is often encountered in clinical practice, with clozapine usually recommended as the appropriate therapy. 2021-07-10 2023-08-13 Not clear
Renato de Filippis, Raffaele Gaetano, Georgios Schoretsanitis, Giuseppe Verde, Cesare Anthony Oliveti, John M Kane, Cristina Segura-Garcia, Pasquale De Fazi. Clozapine Management in Schizophrenia Inpatients: A 5-Year Prospective Observational Study of Its Safety and Tolerability Profile. Neuropsychiatric disease and treatment. vol 17. 2021-07-09. PMID:34234440. clozapine management in schizophrenia inpatients: a 5-year prospective observational study of its safety and tolerability profile. 2021-07-09 2023-08-13 Not clear
Renato de Filippis, Raffaele Gaetano, Georgios Schoretsanitis, Giuseppe Verde, Cesare Anthony Oliveti, John M Kane, Cristina Segura-Garcia, Pasquale De Fazi. Clozapine Management in Schizophrenia Inpatients: A 5-Year Prospective Observational Study of Its Safety and Tolerability Profile. Neuropsychiatric disease and treatment. vol 17. 2021-07-09. PMID:34234440. clozapine is well known for its efficacy and clinical superiority compared to other antipsychotics in treatment-resistant schizophrenia (trs). 2021-07-09 2023-08-13 Not clear
Yasin Hasan Balcioglu, Hasan Gokcay, Umit Haluk Yesilkay. One Plus One Sometimes Equals More Than Two: Long-acting Injectable Aripiprazole Adjunction in Clozapine-Resistant Schizophrenia. Clinical neuropharmacology. vol 43. issue 5. 2021-07-08. PMID:32947430. although we cannot postulate on a single exact mechanism for the increased efficacy of clozapine and aripiprazole combination, we may suggest that, at least for a subgroup of patients with schizophrenia who respond clinically to clozapine at a suboptimal level, combination with aripiprazole may be an effective therapeutic strategy. 2021-07-08 2023-08-13 Not clear
Maxim Kuzin, Georgios Schoretsanitis, Ekkehard Haen, Florian Ridders, Christoph Hiemke, Gerhard Gründer, Michael Paulze. Pharmacokinetic interactions between clozapine and sertraline in smokers and non-smokers. Basic & clinical pharmacology & toxicology. vol 127. issue 4. 2021-07-06. PMID:32307853. clozapine is an effective antipsychotic drug for treatment-resistant schizophrenia. 2021-07-06 2023-08-13 Not clear
Edward Silva, Melanie Higgins, Barbara Hammer, Paul Stephenso. Clozapine re-challenge and initiation following neutropenia: a review and case series of 14 patients in a high-secure forensic hospital. Therapeutic advances in psychopharmacology. vol 11. 2021-07-06. PMID:34221348. clozapine remains the most effective intervention for treatment resistant schizophrenia; however, its use is prohibited following neutropenias. 2021-07-06 2023-08-13 Not clear
Toshihiro Sato, Masato Suzuka, Yuji Sato, Riko Iwabuchi, Daisuke Kobayashi, Jiro Ogura, Shinya Takasaki, Maki Yokota, Taku Tsukamoto, Yoshihiro Hayakawa, Masafumi Kikuchi, Masamitsu Maekawa, Nariyasu Man. Development of a simultaneous analytical method for clozapine and its metabolites in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry with linear range adjusted by in-source collision-induced dissociation. Biomedical chromatography : BMC. vol 35. issue 7. 2021-07-05. PMID:33599311. clozapine (clz) is a key drug in treatment-resistant schizophrenia. 2021-07-05 2023-08-13 human
Tongtong Zhao, Kai Zhang, Yelei Zhang, Yating Yang, Xiaoshuai Ning, Yu Hu, Xiaoyue Li, Yulong Zhang, Lei Xia, Zhenhua Ren, Huanzhong Li. Do proinflammatory cytokines play a role in clozapine-associated glycometabolism disorders? Psychopharmacology. vol 238. issue 7. 2021-07-05. PMID:33774704. clozapine (clz) is the most effective drug for treatment-resistant schizophrenia but is associated with many side effects, including glycometabolism disorders. 2021-07-05 2023-08-13 Not clear
Xuan Li, Xiaoyun Guo, Xiaoduo Fan, Tienan Feng, Chuanyue Wang, Zhijian Yao, Xiufeng Xu, Zhiyu Chen, Huiling Wang, Shoufu Xie, Jiangjiang He, Kaiming Zhuo, Qiong Xiang, Haixin Cen, Jinhong Wang, Robert C Smith, Hua Jin, Matcheri S Keshavan, Stephen R Marder, John M Davis, Kaida Jiang, Yifeng Xu, Dengtang Li. Sequential Multiple-Assignment Randomized Trials to Compare Antipsychotic Treatments (SMART-CAT) in first-episode schizophrenia patients: Rationale and trial design. Schizophrenia research. vol 230. 2021-07-02. PMID:33279374. we hypothesize that clozapine is more therapeutically effective than any other sgas to patients who failed to meet efficacy criteria in phase 1, and earlier treatment with clozapine can improve the functional outcomes of schizophrenia patients. 2021-07-02 2023-08-13 human