| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Skogh, F Bengtsson, C Nordi. Could discontinuing smoking be hazardous for patients administered clozapine medication? A case report. Therapeutic drug monitoring. vol 21. issue 5. 1999-12-14. PMID:10519459. |
a 35-year-old man with schizophrenia was successfully treated with clozapine at a daily oral dose of 700-725 mg for more than 7 consecutive years. |
1999-12-14 |
2023-08-12 |
Not clear |
| T C Manschreck, D A Redmond, S F Candela, B A Mahe. Effects of clozapine on psychiatric symptoms, cognition, and functional outcome in schizophrenia. The Journal of neuropsychiatry and clinical neurosciences. vol 11. issue 4. 1999-12-13. PMID:10570762. |
effects of clozapine on psychiatric symptoms, cognition, and functional outcome in schizophrenia. |
1999-12-13 |
2023-08-12 |
Not clear |
| T C Manschreck, D A Redmond, S F Candela, B A Mahe. Effects of clozapine on psychiatric symptoms, cognition, and functional outcome in schizophrenia. The Journal of neuropsychiatry and clinical neurosciences. vol 11. issue 4. 1999-12-13. PMID:10570762. |
this study focused on the symptomatic and cognitive effects of the atypical antipsychotic clozapine in chronic hospitalized schizophrenia patients. |
1999-12-13 |
2023-08-12 |
Not clear |
| G E Duncan, S Zorn, J A Lieberma. Mechanisms of typical and atypical antipsychotic drug action in relation to dopamine and NMDA receptor hypofunction hypotheses of schizophrenia. Molecular psychiatry. vol 4. issue 5. 1999-12-10. PMID:10523814. |
available evidence indicates that clozapine is the most effective antipsychotic currently used for the pharmacotherapy of schizophrenia. |
1999-12-10 |
2023-08-12 |
Not clear |
| G E Duncan, S Zorn, J A Lieberma. Mechanisms of typical and atypical antipsychotic drug action in relation to dopamine and NMDA receptor hypofunction hypotheses of schizophrenia. Molecular psychiatry. vol 4. issue 5. 1999-12-10. PMID:10523814. |
the present paper briefly reviews the clinical experience with the newer 'atypical' antipsychotic drugs and then discusses clinical and preclinical data potentially relevant to mechanisms of action of clozapine in relation to the nmda receptor hypofunction hypothesis of schizophrenia. |
1999-12-10 |
2023-08-12 |
Not clear |
| K I Melkersson, A L Hulting, K E Brisma. Different influences of classical antipsychotics and clozapine on glucose-insulin homeostasis in patients with schizophrenia or related psychoses. The Journal of clinical psychiatry. vol 60. issue 11. 1999-12-08. PMID:10584769. |
different influences of classical antipsychotics and clozapine on glucose-insulin homeostasis in patients with schizophrenia or related psychoses. |
1999-12-08 |
2023-08-12 |
Not clear |
| G M Simpson, R C Josiassen, J K Stanilla, J de Leon, C Nair, G Abraham, A Odom-White, R M Turne. Double-blind study of clozapine dose response in chronic schizophrenia. The American journal of psychiatry. vol 156. issue 11. 1999-11-16. PMID:10553738. |
double-blind study of clozapine dose response in chronic schizophrenia. |
1999-11-16 |
2023-08-12 |
Not clear |
| G E Tsai, P Yang, L C Chung, I C Tsai, C W Tsai, J T Coyl. D-serine added to clozapine for the treatment of schizophrenia. The American journal of psychiatry. vol 156. issue 11. 1999-11-16. PMID:10553752. |
d-serine added to clozapine for the treatment of schizophrenia. |
1999-11-16 |
2023-08-12 |
Not clear |
| S M Dursun, D McIntosh, H Millike. Clozapine plus lamotrigine in treatment-resistant schizophrenia. Archives of general psychiatry. vol 56. issue 10. 1999-10-29. PMID:10530638. |
clozapine plus lamotrigine in treatment-resistant schizophrenia. |
1999-10-29 |
2023-08-12 |
Not clear |
| S Pallanti, L Quercioli, A Pazzagl. Effects of clozapine on awareness of illness and cognition in schizophrenia. Psychiatry research. vol 86. issue 3. 1999-10-21. PMID:10482343. |
effects of clozapine on awareness of illness and cognition in schizophrenia. |
1999-10-21 |
2023-08-12 |
Not clear |
| P Hertel, M V Fagerquist, T H Svensso. Enhanced cortical dopamine output and antipsychotic-like effects of raclopride by alpha2 adrenoceptor blockade. Science (New York, N.Y.). vol 286. issue 5437. 1999-10-21. PMID:10506554. |
these results challenge basic assumptions underlying the dopamine hypothesis of schizophrenia and provide insight into clozapine's mode of action. |
1999-10-21 |
2023-08-12 |
rat |
| B Spivak, E Musin, R Mester, N Gonen, Y Talmon, N Guy, S Roitman, M Kupchik, M Kotler, A Weizma. The effect of long-term antipsychotic treatment on the body weight of patients suffering from chronic schizophrenia: clozapine versus classical antipsychotic agents. International clinical psychopharmacology. vol 14. issue 4. 1999-10-14. PMID:10468315. |
the effect of long-term antipsychotic treatment on the body weight of patients suffering from chronic schizophrenia: clozapine versus classical antipsychotic agents. |
1999-10-14 |
2023-08-12 |
Not clear |
| H Y Meltzer, S R McGur. The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. Schizophrenia bulletin. vol 25. issue 2. 1999-09-24. PMID:10416729. |
the effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. |
1999-09-24 |
2023-08-12 |
Not clear |
| H Y Meltzer, S R McGur. The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. Schizophrenia bulletin. vol 25. issue 2. 1999-09-24. PMID:10416729. |
we have identified all the studies of clozapine, olanzapine, and risperidone that provide data on their effects on cognition in schizophrenia. |
1999-09-24 |
2023-08-12 |
Not clear |
| A R Mohn, R R Gainetdinov, M G Caron, B H Kolle. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell. vol 98. issue 4. 1999-09-23. PMID:10481908. |
these behavioral alterations are similar to those observed in pharmacologically induced animal models of schizophrenia and can be ameliorated by treatment with haloperidol or clozapine, antipsychotic drugs that antagonize dopaminergic and serotonergic receptors. |
1999-09-23 |
2023-08-12 |
mouse |
| J Judg. Clozapine in schizophrenia. Psychiatric services (Washington, D.C.). vol 50. issue 8. 1999-09-10. PMID:10445662. |
clozapine in schizophrenia. |
1999-09-10 |
2023-08-12 |
Not clear |
| K Stengler-Wenzk. [Presentation of obsessive-compulsive symptoms in a patient with schizophrenia treated with clozapine]. Psychiatrische Praxis. vol 26. issue 3. 1999-09-08. PMID:10412713. |
[presentation of obsessive-compulsive symptoms in a patient with schizophrenia treated with clozapine]. |
1999-09-08 |
2023-08-12 |
Not clear |
| K Stengler-Wenzk. [Presentation of obsessive-compulsive symptoms in a patient with schizophrenia treated with clozapine]. Psychiatrische Praxis. vol 26. issue 3. 1999-09-08. PMID:10412713. |
we report on the case of a 31-year old man with chronic schizophrenia who had shown obsessive-compulsive symptoms during treatment with clozapine. |
1999-09-08 |
2023-08-12 |
Not clear |
| T I Prior, P S Chue, P Tibbo, G B Bake. Drug metabolism and atypical antipsychotics. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 9. issue 4. 1999-09-03. PMID:10422890. |
the introduction of the atypical antipsychotics clozapine, risperidone, olanzapine, quetiapine and sertindole for the treatment of schizophrenia has coincided with an increased awareness of the potential of drug-drug interactions, particularly involving the cytochrome p450 (cyp) enzymes. |
1999-09-03 |
2023-08-12 |
Not clear |
| A Ahokas, E Elone. Circadian rhythm of white blood cells during clozapine treatment. Psychopharmacology. vol 144. issue 3. 1999-09-02. PMID:10435399. |
the atypical antipsychotic clozapine is effective in the treatment of patients with refractory schizophrenia. |
1999-09-02 |
2023-08-12 |
Not clear |