| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H E Shannon, K Rasmussen, F P Bymaster, J C Hart, S C Peters, M D Swedberg, L Jeppesen, M J Sheardown, P Sauerberg, A Fink-Jense. Xanomeline, an M(1)/M(4) preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice. Schizophrenia research. vol 42. issue 3. 2000-07-11. PMID:10785583. |
the present results thus demonstrate that xanomeline has a pharmacologic profile which is similar to that of the atypical antipsychotics clozapine and olanzapine, thus indicating that xanomeline has the potential to be a novel approach in the treatment of psychotic symptoms in patients with schizophrenia. |
2000-07-11 |
2023-08-12 |
mouse |
| K Wahlbeck, M Cheine, M A Essal. Clozapine versus typical neuroleptic medication for schizophrenia. The Cochrane database of systematic reviews. issue 2. 2000-07-06. PMID:10796289. |
clozapine versus typical neuroleptic medication for schizophrenia. |
2000-07-06 |
2023-08-12 |
Not clear |
| A Tuunainen, K Wahlbeck, S M Gilbod. Newer atypical antipsychotic medication versus clozapine for schizophrenia. The Cochrane database of systematic reviews. issue 2. 2000-07-06. PMID:10796559. |
newer atypical antipsychotic medication versus clozapine for schizophrenia. |
2000-07-06 |
2023-08-12 |
Not clear |
| J Waserman, M Crioll. Subjective experiences of clozapine treatment by patients with chronic schizophrenia. Psychiatric services (Washington, D.C.). vol 51. issue 5. 2000-06-27. PMID:10783189. |
subjective experiences of clozapine treatment by patients with chronic schizophrenia. |
2000-06-27 |
2023-08-12 |
Not clear |
| M Sajatovic, C R Bingham, D Garver, L F Ramirez, G Ripper, F Blow, L S Lehman. An assessment of clinical practice of clozapine therapy for veterans. Psychiatric services (Washington, D.C.). vol 51. issue 5. 2000-06-27. PMID:10783190. |
clozapine therapy for 2,996 patients with treatment-refractory schizophrenia was examined over a five-year period in the veterans affairs health care system. |
2000-06-27 |
2023-08-12 |
Not clear |
| A E Evins, S M Fitzgerald, L Wine, R Rosselli, D C Gof. Placebo-controlled trial of glycine added to clozapine in schizophrenia. The American journal of psychiatry. vol 157. issue 5. 2000-05-17. PMID:10784481. |
placebo-controlled trial of glycine added to clozapine in schizophrenia. |
2000-05-17 |
2023-08-12 |
Not clear |
| A E Evins, S M Fitzgerald, L Wine, R Rosselli, D C Gof. Placebo-controlled trial of glycine added to clozapine in schizophrenia. The American journal of psychiatry. vol 157. issue 5. 2000-05-17. PMID:10784481. |
the purpose of this study was to evaluate the effects of high-dose oral glycine on positive and negative symptoms and cognitive function when added to clozapine in adults with schizophrenia. |
2000-05-17 |
2023-08-12 |
Not clear |
| J Munro, D O'Sullivan, C Andrews, A Arana, A Mortimer, R Kerwi. Active monitoring of 12,760 clozapine recipients in the UK and Ireland. Beyond pharmacovigilance. The British journal of psychiatry : the journal of mental science. vol 175. 2000-05-12. PMID:10789357. |
people prescribed clozapine for treatment-resistant schizophrenia have mandatory haematological monitoring through a case register for identifying reversible neutropenia. |
2000-05-12 |
2023-08-12 |
Not clear |
| R Berecz, T Glaub, M Kellermann, A de la Rubia, A Llerena, I Degrel. Clozapine withdrawal symptoms after change to sertindole in a schizophrenic patient. Pharmacopsychiatry. vol 33. issue 1. 2000-05-10. PMID:10721883. |
a 30-year-old male patient with paranoid schizophrenia was on clozapine therapy for more than five years. |
2000-05-10 |
2023-08-12 |
Not clear |
| S A Chong, G J Remington, N Lee, R Mahendra. Contrasting clozapine prescribing patterns in the east and west? Annals of the Academy of Medicine, Singapore. vol 29. issue 1. 2000-05-04. PMID:10748970. |
in this survey, we compared the effect of clozapine, an atypical neuroleptic, on polypharmacy in two groups of patients with schizophrenia in two different settings. |
2000-05-04 |
2023-08-12 |
Not clear |
| J P Pandarakala. Atypical neuroleptics. Hospital medicine (London, England : 1998). vol 61. issue 1. 2000-04-20. PMID:10735147. |
the discovery that clozapine alleviates both positive and negative symptoms of schizophrenia has resulted in the emergence of newer atypical neuroleptics. |
2000-04-20 |
2023-08-12 |
Not clear |
| N J Brugman, D Cohen, R H de Vrie. [Diabetes mellitus after treatment with clozapine]. Nederlands tijdschrift voor geneeskunde. vol 144. issue 9. 2000-04-05. PMID:10719549. |
in a 40-year old patient with schizophrenia treated with sustained-action perfenazine for schizophrenia, diabetes mellitus type 2 and hypertension developed when clozapine was added to the regimen. |
2000-04-05 |
2023-08-12 |
Not clear |
| V M Rodriguez, M L Catalina, J A García-Noblejas, P Cuest. Schizophrenic syndromes and clozapine response in treatment-resistant schizophrenia. Psychiatry research. vol 77. issue 1. 2000-03-31. PMID:10710171. |
schizophrenic syndromes and clozapine response in treatment-resistant schizophrenia. |
2000-03-31 |
2023-08-12 |
Not clear |
| P E Keck, S M Strakowski, S L McElro. The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility, and suicidality in patients with schizophrenia. The Journal of clinical psychiatry. vol 61 Suppl 3. 2000-03-22. PMID:10724127. |
for this article, the available literature regarding the efficacy of clozapine, risperidone, olanzapine, quetiapine, and ziprasidone in the treatment of depression, hostility, and suicidality in patients with schizophrenia was reviewed. |
2000-03-22 |
2023-08-12 |
Not clear |
| P E Keck, S M Strakowski, S L McElro. The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility, and suicidality in patients with schizophrenia. The Journal of clinical psychiatry. vol 61 Suppl 3. 2000-03-22. PMID:10724127. |
these studies suggest that atypical antipsychotics may exert therapeutic effects on depression and hostility as well as psychosis and that clozapine and olanzapine may reduce suicidality in patients with schizophrenia. |
2000-03-22 |
2023-08-12 |
Not clear |
| M Masellis, V S Basile, V Ozdemir, H Y Meltzer, F M Macciardi, J L Kenned. Pharmacogenetics of antipsychotic treatment: lessons learned from clozapine. Biological psychiatry. vol 47. issue 3. 2000-03-17. PMID:10682223. |
the reintroduction of clozapine, the prototype of atypical antipsychotics, in the late 1980s has led to significant advances in the pharmacological management of schizophrenia. |
2000-03-17 |
2023-08-12 |
Not clear |
| S V Zimmet, R D Strous, E S Burgess, S Kohnstamm, A I Gree. Effects of clozapine on substance use in patients with schizophrenia and schizoaffective disorder: a retrospective survey. Journal of clinical psychopharmacology. vol 20. issue 1. 2000-03-15. PMID:10653215. |
effects of clozapine on substance use in patients with schizophrenia and schizoaffective disorder: a retrospective survey. |
2000-03-15 |
2023-08-12 |
Not clear |
| S V Zimmet, R D Strous, E S Burgess, S Kohnstamm, A I Gree. Effects of clozapine on substance use in patients with schizophrenia and schizoaffective disorder: a retrospective survey. Journal of clinical psychopharmacology. vol 20. issue 1. 2000-03-15. PMID:10653215. |
the authors report data from a retrospective survey of substance use in 58 patients treated with clozapine who had a history of comorbid schizophrenia (or schizoaffective disorder) and substance use disorder. |
2000-03-15 |
2023-08-12 |
Not clear |
| J A Worrel, P A Marken, S E Beckman, V L Ruehte. Atypical antipsychotic agents: a critical review. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. vol 57. issue 3. 2000-03-09. PMID:10674777. |
clozapine remains the standard agent for treatment-resistant schizophrenia. |
2000-03-09 |
2023-08-12 |
Not clear |
| S A Chong, G J Remington, K Z Bezchlibnyk-Butle. Effect of clozapine on polypharmacy. Psychiatric services (Washington, D.C.). vol 51. issue 2. 2000-03-06. PMID:10655014. |
prescribing patterns for a group of outpatients with schizophrenia were surveyed for changes after the initiation of clozapine. |
2000-03-06 |
2023-08-12 |
Not clear |