| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Tamam, N Ozpoyra. Suicide during clozapine treatment: a case report. The Israel journal of psychiatry and related sciences. vol 38. issue 2. 2001-08-30. PMID:11475915. |
in this case report, we presented a schizophrenia patient with several risk factors who committed suicide during clozapine treatment. |
2001-08-30 |
2023-08-12 |
Not clear |
| L Tamam, N Ozpoyra. Suicide during clozapine treatment: a case report. The Israel journal of psychiatry and related sciences. vol 38. issue 2. 2001-08-30. PMID:11475915. |
risk factors prominent in this case including increased awareness after improvement in chronic state, planned discharge in the near future, and the notion of reduced suicidality in schizophrenia patients during clozapine treatment are discussed in this article based on the literature and the case. |
2001-08-30 |
2023-08-12 |
Not clear |
| J M Azorin, R Spiegel, G Remington, J M Vanelle, J J Péré, M Giguere, I Bourdei. A double-blind comparative study of clozapine and risperidone in the management of severe chronic schizophrenia. The American journal of psychiatry. vol 158. issue 8. 2001-08-30. PMID:11481167. |
a double-blind comparative study of clozapine and risperidone in the management of severe chronic schizophrenia. |
2001-08-30 |
2023-08-12 |
Not clear |
| J M Azorin, R Spiegel, G Remington, J M Vanelle, J J Péré, M Giguere, I Bourdei. A double-blind comparative study of clozapine and risperidone in the management of severe chronic schizophrenia. The American journal of psychiatry. vol 158. issue 8. 2001-08-30. PMID:11481167. |
this prospective, double-blind, multicenter, parallel-group study compared the efficacy and safety of therapeutic doses of clozapine and risperidone in patients with severe chronic schizophrenia and poor previous treatment response. |
2001-08-30 |
2023-08-12 |
Not clear |
| H Y Meltze. Treatment of suicidality in schizophrenia. Annals of the New York Academy of Sciences. vol 932. 2001-08-23. PMID:11411190. |
however, several types of evidence suggest that clozapine, an atypical antipsychotic drug, appreciably reduces the suicide attempt and completion rates in schizophrenia and schizoaffective disorder, perhaps by as much as 75-85%. |
2001-08-23 |
2023-08-12 |
Not clear |
| S J Tsai, Y C Wang, W Y Yu Younger, C H Lin, K H Yang, C J Hon. Association analysis of polymorphism in the promoter region of the alpha2a-adrenoceptor gene with schizophrenia and clozapine response. Schizophrenia research. vol 49. issue 1-2. 2001-08-09. PMID:11343863. |
association analysis of polymorphism in the promoter region of the alpha2a-adrenoceptor gene with schizophrenia and clozapine response. |
2001-08-09 |
2023-08-12 |
Not clear |
| S J Tsai, Y C Wang, W Y Yu Younger, C H Lin, K H Yang, C J Hon. Association analysis of polymorphism in the promoter region of the alpha2a-adrenoceptor gene with schizophrenia and clozapine response. Schizophrenia research. vol 49. issue 1-2. 2001-08-09. PMID:11343863. |
the results of clozapine treatment demonstrated that the alpha2a-adrenoceptor gene variants did not play a major role in the susceptibility, hypersalivation adverse effect or clozapine response of patients with schizophrenia. |
2001-08-09 |
2023-08-12 |
Not clear |
| V Knott, A Labelle, B Jones, C Mahone. Quantitative EEG in schizophrenia and in response to acute and chronic clozapine treatment. Schizophrenia research. vol 50. issue 1-2. 2001-08-09. PMID:11378313. |
quantitative eeg in schizophrenia and in response to acute and chronic clozapine treatment. |
2001-08-09 |
2023-08-12 |
human |
| P F Buckley, L Friedman, A C Krowinski, Y Eaton, M Tronetti, D D Mille. Clinical and biochemical correlates of "high-dose" clozapine therapy for treatment-refractory schizophrenia. Schizophrenia research. vol 49. issue 1-2. 2001-08-09. PMID:11428347. |
clinical and biochemical correlates of "high-dose" clozapine therapy for treatment-refractory schizophrenia. |
2001-08-09 |
2023-08-12 |
Not clear |
| S L Joutsiniemi, A Gross, B Appelber. Marked clozapine-induced slowing of EEG background over frontal, central, and parietal scalp areas in schizophrenic patients. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. vol 18. issue 1. 2001-08-02. PMID:11290933. |
the authors studied how clozapine treatment of patients with chronic schizophrenia affects the scalp topographic distribution of different frequency bands on eeg. |
2001-08-02 |
2023-08-12 |
human |
| S L Joutsiniemi, A Gross, B Appelber. Marked clozapine-induced slowing of EEG background over frontal, central, and parietal scalp areas in schizophrenic patients. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. vol 18. issue 1. 2001-08-02. PMID:11290933. |
twenty-one patients treated with clozapine, in addition to zero to two typical neuroleptics (13 patients were treated with clozapine as the only neuroleptic), were compared with two control groups: one of healthy subjects and another of patients with schizophrenia receiving one to three typical neuroleptics and no clozapine. |
2001-08-02 |
2023-08-12 |
human |
| G Remington, I Khramo. Health care utilization in patients with schizophrenia maintained on atypical versus conventional antipsychotics. Progress in neuro-psychopharmacology & biological psychiatry. vol 25. issue 2. 2001-08-02. PMID:11294482. |
patients with schizophrenia who had been stabilized on their antipsychotic medication and subsequently maintained on it for a period of at least 18 months were identified: clozapine (n=15); risperidone (n=15); depot conventional (n=18); oral conventional (n=18). |
2001-08-02 |
2023-08-12 |
Not clear |
| J D Rollnik, U Schneider, H M Emric. [Successful treatment of simple schizophrenia with atypical neuroleptics (clozapine, risperidol)]. Der Nervenarzt. vol 72. issue 5. 2001-08-02. PMID:11386150. |
[successful treatment of simple schizophrenia with atypical neuroleptics (clozapine, risperidol)]. |
2001-08-02 |
2023-08-12 |
Not clear |
| K Reitzle, A Warnke, C Wewetzer, H Mülle. [Agranulocytosis in a child with schizophrenia treated with clozapine--clinical findings and therapy, a case report]. Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie. vol 29. issue 2. 2001-08-02. PMID:11393052. |
[agranulocytosis in a child with schizophrenia treated with clozapine--clinical findings and therapy, a case report]. |
2001-08-02 |
2023-08-12 |
Not clear |
| P E Konicki, K Y Kwon, V Steele, J White, M Fuller, G J Jurjus, G E Jaski. Prefrontal cortical sulcal widening associated with poor treatment response to clozapine. Schizophrenia research. vol 48. issue 2-3. 2001-07-19. PMID:11295370. |
increased sulcal widening in the prefrontal cortex of patients with schizophrenia may be associated with a poor treatment response to clozapine. |
2001-07-19 |
2023-08-12 |
Not clear |
| M Marchini, R Scorza, R Antonioli, S Scarone, B Grassi, M Epifani, C Dragon. HLA-A2 and B35 are strong predictors of responsiveness to clozapine: preliminary data in Italian schizophrenia patients. Schizophrenia research. vol 48. issue 2-3. 2001-07-19. PMID:11368031. |
hla-a2 and b35 are strong predictors of responsiveness to clozapine: preliminary data in italian schizophrenia patients. |
2001-07-19 |
2023-08-12 |
Not clear |
| B A Ellenbroek, J F Liégeois, J Bruhwyler, A R Cool. Effects of JL13, a pyridobenzoxazepine with potential atypical antipsychotic activity, in animal models for schizophrenia. The Journal of pharmacology and experimental therapeutics. vol 298. issue 1. 2001-07-19. PMID:11408566. |
in the present study, jl13 was compared with clozapine and haloperidol in several animal models for schizophrenia. |
2001-07-19 |
2023-08-12 |
rat |
| T Tallerico, G Novak, I S Liu, C Ulpian, P Seema. Schizophrenia: elevated mRNA for dopamine D2(Longer) receptors in frontal cortex. Brain research. Molecular brain research. vol 87. issue 2. 2001-06-28. PMID:11245917. |
because dopamine d2 receptors are the primary targets for antipsychotic drugs, including clozapine and quetiapine, and because some studies have found d2 receptors to be elevated in schizophrenia, we examined the mrna of three forms of the d2 receptor, particularly the new form of the dopamine d2 receptor, d2(longer), in post-mortem brains from patients who died with schizophrenia. |
2001-06-28 |
2023-08-12 |
Not clear |
| J Feng, J Zheng, J Gelernter, H Kranzler, E Cook, D Goldman, I R Jones, N Craddock, L L Heston, L Delisi, L Peltonen, W P Bennett, S S Somme. An in-frame deletion in the alpha(2C) adrenergic receptor is common in African--Americans. Molecular psychiatry. vol 6. issue 2. 2001-06-28. PMID:11317218. |
the alpha(2c) adrenergic receptor (adra2c), located on chromosome 4p16.3, is a candidate gene for schizophrenia because it binds clozapine, an atypical neuroleptic useful for treatment-resistant schizophrenia. |
2001-06-28 |
2023-08-12 |
Not clear |
| M J Sernyak, R Desai, M Stolar, R Rosenhec. Impact of clozapine on completed suicide. The American journal of psychiatry. vol 158. issue 6. 2001-06-28. PMID:11384902. |
clozapine has been found to be superior to typical neuroleptics in ameliorating the symptoms of refractory schizophrenia. |
2001-06-28 |
2023-08-12 |
Not clear |