| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S L Joutsiniemi, A Gross, B Appelber. Marked clozapine-induced slowing of EEG background over frontal, central, and parietal scalp areas in schizophrenic patients. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. vol 18. issue 1. 2001-08-02. PMID:11290933. |
the authors studied how clozapine treatment of patients with chronic schizophrenia affects the scalp topographic distribution of different frequency bands on eeg. |
2001-08-02 |
2023-08-12 |
human |
| S L Joutsiniemi, A Gross, B Appelber. Marked clozapine-induced slowing of EEG background over frontal, central, and parietal scalp areas in schizophrenic patients. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. vol 18. issue 1. 2001-08-02. PMID:11290933. |
twenty-one patients treated with clozapine, in addition to zero to two typical neuroleptics (13 patients were treated with clozapine as the only neuroleptic), were compared with two control groups: one of healthy subjects and another of patients with schizophrenia receiving one to three typical neuroleptics and no clozapine. |
2001-08-02 |
2023-08-12 |
human |
| G Remington, I Khramo. Health care utilization in patients with schizophrenia maintained on atypical versus conventional antipsychotics. Progress in neuro-psychopharmacology & biological psychiatry. vol 25. issue 2. 2001-08-02. PMID:11294482. |
patients with schizophrenia who had been stabilized on their antipsychotic medication and subsequently maintained on it for a period of at least 18 months were identified: clozapine (n=15); risperidone (n=15); depot conventional (n=18); oral conventional (n=18). |
2001-08-02 |
2023-08-12 |
Not clear |
| J D Rollnik, U Schneider, H M Emric. [Successful treatment of simple schizophrenia with atypical neuroleptics (clozapine, risperidol)]. Der Nervenarzt. vol 72. issue 5. 2001-08-02. PMID:11386150. |
[successful treatment of simple schizophrenia with atypical neuroleptics (clozapine, risperidol)]. |
2001-08-02 |
2023-08-12 |
Not clear |
| K Reitzle, A Warnke, C Wewetzer, H Mülle. [Agranulocytosis in a child with schizophrenia treated with clozapine--clinical findings and therapy, a case report]. Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie. vol 29. issue 2. 2001-08-02. PMID:11393052. |
[agranulocytosis in a child with schizophrenia treated with clozapine--clinical findings and therapy, a case report]. |
2001-08-02 |
2023-08-12 |
Not clear |
| P E Konicki, K Y Kwon, V Steele, J White, M Fuller, G J Jurjus, G E Jaski. Prefrontal cortical sulcal widening associated with poor treatment response to clozapine. Schizophrenia research. vol 48. issue 2-3. 2001-07-19. PMID:11295370. |
increased sulcal widening in the prefrontal cortex of patients with schizophrenia may be associated with a poor treatment response to clozapine. |
2001-07-19 |
2023-08-12 |
Not clear |
| M Marchini, R Scorza, R Antonioli, S Scarone, B Grassi, M Epifani, C Dragon. HLA-A2 and B35 are strong predictors of responsiveness to clozapine: preliminary data in Italian schizophrenia patients. Schizophrenia research. vol 48. issue 2-3. 2001-07-19. PMID:11368031. |
hla-a2 and b35 are strong predictors of responsiveness to clozapine: preliminary data in italian schizophrenia patients. |
2001-07-19 |
2023-08-12 |
Not clear |
| B A Ellenbroek, J F Liégeois, J Bruhwyler, A R Cool. Effects of JL13, a pyridobenzoxazepine with potential atypical antipsychotic activity, in animal models for schizophrenia. The Journal of pharmacology and experimental therapeutics. vol 298. issue 1. 2001-07-19. PMID:11408566. |
in the present study, jl13 was compared with clozapine and haloperidol in several animal models for schizophrenia. |
2001-07-19 |
2023-08-12 |
rat |
| T Tallerico, G Novak, I S Liu, C Ulpian, P Seema. Schizophrenia: elevated mRNA for dopamine D2(Longer) receptors in frontal cortex. Brain research. Molecular brain research. vol 87. issue 2. 2001-06-28. PMID:11245917. |
because dopamine d2 receptors are the primary targets for antipsychotic drugs, including clozapine and quetiapine, and because some studies have found d2 receptors to be elevated in schizophrenia, we examined the mrna of three forms of the d2 receptor, particularly the new form of the dopamine d2 receptor, d2(longer), in post-mortem brains from patients who died with schizophrenia. |
2001-06-28 |
2023-08-12 |
Not clear |
| J Feng, J Zheng, J Gelernter, H Kranzler, E Cook, D Goldman, I R Jones, N Craddock, L L Heston, L Delisi, L Peltonen, W P Bennett, S S Somme. An in-frame deletion in the alpha(2C) adrenergic receptor is common in African--Americans. Molecular psychiatry. vol 6. issue 2. 2001-06-28. PMID:11317218. |
the alpha(2c) adrenergic receptor (adra2c), located on chromosome 4p16.3, is a candidate gene for schizophrenia because it binds clozapine, an atypical neuroleptic useful for treatment-resistant schizophrenia. |
2001-06-28 |
2023-08-12 |
Not clear |
| M J Sernyak, R Desai, M Stolar, R Rosenhec. Impact of clozapine on completed suicide. The American journal of psychiatry. vol 158. issue 6. 2001-06-28. PMID:11384902. |
clozapine has been found to be superior to typical neuroleptics in ameliorating the symptoms of refractory schizophrenia. |
2001-06-28 |
2023-08-12 |
Not clear |
| T Bast, W N Zhang, C Heidbreder, J Feldo. Hyperactivity and disruption of prepulse inhibition induced by N-methyl-D-aspartate stimulation of the ventral hippocampus and the effects of pretreatment with haloperidol and clozapine. Neuroscience. vol 103. issue 2. 2001-06-14. PMID:11246148. |
the present finding that both clozapine and haloperidol failed to antagonize the disruption of prepulse inhibition induced by n-methyl-d-aspartate stimulation of the ventral hippocampus is discussed with respect to our previous contrary finding concerning the ameliorative effect of clozapine and with respect to the disruption of prepulse inhibition in rats being considered as a model of sensorimotor gating deficits in schizophrenia. |
2001-06-14 |
2023-08-12 |
rat |
| S A Alle. Effect of chlorpromazine and clozapine on plasma concentrations of haloperidol in a patient with schizophrenia. Journal of clinical pharmacology. vol 40. issue 11. 2001-05-31. PMID:11075316. |
effect of chlorpromazine and clozapine on plasma concentrations of haloperidol in a patient with schizophrenia. |
2001-05-31 |
2023-08-12 |
Not clear |
| S A Alle. Effect of chlorpromazine and clozapine on plasma concentrations of haloperidol in a patient with schizophrenia. Journal of clinical pharmacology. vol 40. issue 11. 2001-05-31. PMID:11075316. |
a 40-year-old patient being treated for schizophrenia developed elevated plasma levels of haloperidol (hal) in combination with chlorpromazine (cpz) and during overlap treatment with clozapine. |
2001-05-31 |
2023-08-12 |
Not clear |
| S E Purdon, A Labelle, L Boula. Neuropsychological change in schizophrenia after 6 weeks of clozapine. Schizophrenia research. vol 48. issue 1. 2001-05-31. PMID:11278154. |
neuropsychological change in schizophrenia after 6 weeks of clozapine. |
2001-05-31 |
2023-08-12 |
Not clear |
| B Mullen, J S Brar, A H Vagnucci, R Gangul. Frequency of sexual dysfunctions in patients with schizophrenia on haloperidol, clozapine or risperidone. Schizophrenia research. vol 48. issue 1. 2001-05-31. PMID:11345946. |
frequency of sexual dysfunctions in patients with schizophrenia on haloperidol, clozapine or risperidone. |
2001-05-31 |
2023-08-12 |
Not clear |
| W K Tang, G S Ungvar. Electroconvulsive therapy in rehabilitation: the Hong Kong experience. Psychiatric services (Washington, D.C.). vol 52. issue 3. 2001-05-17. PMID:11239096. |
the introduction of clozapine has enlarged the proportion of individuals with schizophrenia whose psychotic symptoms can be controlled (2), but symptoms remain refractory in a large number of patients. |
2001-05-17 |
2023-08-12 |
Not clear |
| M Masellis, V S Basile, H Y Meltzer, J A Lieberman, S Sevy, D A Goldman, M W Hamblin, F M Macciardi, J L Kenned. Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia. Schizophrenia research. vol 47. issue 1. 2001-04-26. PMID:11163544. |
lack of association between the t-->c 267 serotonin 5-ht6 receptor gene (htr6) polymorphism and prediction of response to clozapine in schizophrenia. |
2001-04-26 |
2023-08-12 |
Not clear |
| M Masellis, V S Basile, H Y Meltzer, J A Lieberman, S Sevy, D A Goldman, M W Hamblin, F M Macciardi, J L Kenned. Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia. Schizophrenia research. vol 47. issue 1. 2001-04-26. PMID:11163544. |
we employed a pharmacogenetic approach in a group (n=185) of schizophrenia patients that have been clinically well characterized for clozapine response. |
2001-04-26 |
2023-08-12 |
Not clear |
| F E Scheepers, C C Gispen de Wied, H E Hulshoff Pol, R S Kah. Effect of clozapine on caudate nucleus volume in relation to symptoms of schizophrenia. The American journal of psychiatry. vol 158. issue 4. 2001-04-26. PMID:11282704. |
effect of clozapine on caudate nucleus volume in relation to symptoms of schizophrenia. |
2001-04-26 |
2023-08-12 |
Not clear |