| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V S Basile, M Masellis, R S McIntyre, H Y Meltzer, J A Lieberman, J L Kenned. Genetic dissection of atypical antipsychotic-induced weight gain: novel preliminary data on the pharmacogenetic puzzle. The Journal of clinical psychiatry. vol 62 Suppl 23. 2001-11-01. PMID:11603885. |
prospective weight gain data were obtained for 80 patients with schizophrenia who completed a structured clozapine trial. |
2001-11-01 |
2023-08-12 |
Not clear |
| O Ohmori, T Shinkai, H Hori, J Nakamur. Novel polymorphism in the 5'-upstream region of the human 5-HT6 receptor gene and schizophrenia. Neuroscience letters. vol 310. issue 1. 2001-10-25. PMID:11524147. |
the localization of 5-hydroxytryptamine6 (5-ht6) receptor in the limbic and cortical regions, and the high affinity of atypical antipsychotic drugs such as clozapine for the receptor, suggest the possible involvement of the receptor in the pathogenesis of schizophrenia. |
2001-10-25 |
2023-08-12 |
human |
| G Orr, H Munitz, H Hermes. Low-dose clozapine for the treatment of Parkinson's disease in a patient with schizophrenia. Clinical neuropharmacology. vol 24. issue 2. 2001-10-18. PMID:11307050. |
low-dose clozapine for the treatment of parkinson's disease in a patient with schizophrenia. |
2001-10-18 |
2023-08-12 |
Not clear |
| G Orr, H Munitz, H Hermes. Low-dose clozapine for the treatment of Parkinson's disease in a patient with schizophrenia. Clinical neuropharmacology. vol 24. issue 2. 2001-10-18. PMID:11307050. |
this report suggests that some patients with concomitant schizophrenia and pd-a difficult treatment challenge-may benefit from clozapine treatment alone for both disorders. |
2001-10-18 |
2023-08-12 |
Not clear |
| H Cohen, U Loewenthal, M A Matar, M Kotle. Reversal of pathologic cardiac parameters after transition from clozapine to olanzapine treatment: a case report. Clinical neuropharmacology. vol 24. issue 2. 2001-10-18. PMID:11307047. |
we present a case of a patient with long-standing schizophrenia who was treated with clozapine. |
2001-10-18 |
2023-08-12 |
Not clear |
| J Cramer, R Rosenheck, W Xu, W Henderson, J Thomas, D Charne. Detecting improvement in quality of life and symptomatology in schizophrenia. Schizophrenia bulletin. vol 27. issue 2. 2001-10-11. PMID:11354590. |
the veterans affairs (va) cooperative study of clozapine in refractory schizophrenia evaluated 423 patients on clozapine or haloperidol. |
2001-10-11 |
2023-08-12 |
Not clear |
| B K Lipska, Z Z Khaing, C S Weickert, D R Weinberge. BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs. The European journal of neuroscience. vol 14. issue 1. 2001-09-27. PMID:11488957. |
to clarify the effects of antipsychotic drugs used in the therapy of schizophrenia on bdnf mrna, we studied its expression in rats treated with clozapine and haloperidol and in rats with neonatal lesions of the ventral hippocampus, used as an animal model of schizophrenia. |
2001-09-27 |
2023-08-12 |
rat |
| D C Henderson, D C Goff, C E Connolly, C P Borba, D Hayde. Risperidone added to clozapine: impact on serum prolactin levels. The Journal of clinical psychiatry. vol 62. issue 8. 2001-09-27. PMID:11561931. |
several years ago, we reported that the addition of risperidone to clozapine improved response in some patients with schizophrenia. |
2001-09-27 |
2023-08-12 |
Not clear |
| D C Henderson, D C Goff, C E Connolly, C P Borba, D Hayde. Risperidone added to clozapine: impact on serum prolactin levels. The Journal of clinical psychiatry. vol 62. issue 8. 2001-09-27. PMID:11561931. |
the goal of this study was to determine whether the addition of risperidone to clozapine results in an elevation of serum prolactin levels in patients with chronic schizophrenia or schizoaffective disorder. |
2001-09-27 |
2023-08-12 |
Not clear |
| S J Tsai, Y H Huang, H J Huang, C B Si. Reduced regional [14C]2-deoxyglucose uptake in response to long-term clozapine administration in rats. Neuropsychobiology. vol 44. issue 1. 2001-08-30. PMID:11408791. |
clozapine has superior effects in treating negative symptoms of schizophrenia and causes less extrapyramidal side effects than traditional antipsychotics. |
2001-08-30 |
2023-08-12 |
rat |
| L Tamam, N Ozpoyra. Suicide during clozapine treatment: a case report. The Israel journal of psychiatry and related sciences. vol 38. issue 2. 2001-08-30. PMID:11475915. |
although clozapine, along with its other significant features, has been reported to decrease suicidality and suicide rate among schizophrenia patients, physicians should remain vigilant for general risk factors of suicide in patients with schizophrenia during a treatment course and assess them carefully. |
2001-08-30 |
2023-08-12 |
Not clear |
| L Tamam, N Ozpoyra. Suicide during clozapine treatment: a case report. The Israel journal of psychiatry and related sciences. vol 38. issue 2. 2001-08-30. PMID:11475915. |
in this case report, we presented a schizophrenia patient with several risk factors who committed suicide during clozapine treatment. |
2001-08-30 |
2023-08-12 |
Not clear |
| L Tamam, N Ozpoyra. Suicide during clozapine treatment: a case report. The Israel journal of psychiatry and related sciences. vol 38. issue 2. 2001-08-30. PMID:11475915. |
risk factors prominent in this case including increased awareness after improvement in chronic state, planned discharge in the near future, and the notion of reduced suicidality in schizophrenia patients during clozapine treatment are discussed in this article based on the literature and the case. |
2001-08-30 |
2023-08-12 |
Not clear |
| J M Azorin, R Spiegel, G Remington, J M Vanelle, J J Péré, M Giguere, I Bourdei. A double-blind comparative study of clozapine and risperidone in the management of severe chronic schizophrenia. The American journal of psychiatry. vol 158. issue 8. 2001-08-30. PMID:11481167. |
a double-blind comparative study of clozapine and risperidone in the management of severe chronic schizophrenia. |
2001-08-30 |
2023-08-12 |
Not clear |
| J M Azorin, R Spiegel, G Remington, J M Vanelle, J J Péré, M Giguere, I Bourdei. A double-blind comparative study of clozapine and risperidone in the management of severe chronic schizophrenia. The American journal of psychiatry. vol 158. issue 8. 2001-08-30. PMID:11481167. |
this prospective, double-blind, multicenter, parallel-group study compared the efficacy and safety of therapeutic doses of clozapine and risperidone in patients with severe chronic schizophrenia and poor previous treatment response. |
2001-08-30 |
2023-08-12 |
Not clear |
| H Y Meltze. Treatment of suicidality in schizophrenia. Annals of the New York Academy of Sciences. vol 932. 2001-08-23. PMID:11411190. |
however, several types of evidence suggest that clozapine, an atypical antipsychotic drug, appreciably reduces the suicide attempt and completion rates in schizophrenia and schizoaffective disorder, perhaps by as much as 75-85%. |
2001-08-23 |
2023-08-12 |
Not clear |
| S J Tsai, Y C Wang, W Y Yu Younger, C H Lin, K H Yang, C J Hon. Association analysis of polymorphism in the promoter region of the alpha2a-adrenoceptor gene with schizophrenia and clozapine response. Schizophrenia research. vol 49. issue 1-2. 2001-08-09. PMID:11343863. |
association analysis of polymorphism in the promoter region of the alpha2a-adrenoceptor gene with schizophrenia and clozapine response. |
2001-08-09 |
2023-08-12 |
Not clear |
| S J Tsai, Y C Wang, W Y Yu Younger, C H Lin, K H Yang, C J Hon. Association analysis of polymorphism in the promoter region of the alpha2a-adrenoceptor gene with schizophrenia and clozapine response. Schizophrenia research. vol 49. issue 1-2. 2001-08-09. PMID:11343863. |
the results of clozapine treatment demonstrated that the alpha2a-adrenoceptor gene variants did not play a major role in the susceptibility, hypersalivation adverse effect or clozapine response of patients with schizophrenia. |
2001-08-09 |
2023-08-12 |
Not clear |
| V Knott, A Labelle, B Jones, C Mahone. Quantitative EEG in schizophrenia and in response to acute and chronic clozapine treatment. Schizophrenia research. vol 50. issue 1-2. 2001-08-09. PMID:11378313. |
quantitative eeg in schizophrenia and in response to acute and chronic clozapine treatment. |
2001-08-09 |
2023-08-12 |
human |
| P F Buckley, L Friedman, A C Krowinski, Y Eaton, M Tronetti, D D Mille. Clinical and biochemical correlates of "high-dose" clozapine therapy for treatment-refractory schizophrenia. Schizophrenia research. vol 49. issue 1-2. 2001-08-09. PMID:11428347. |
clinical and biochemical correlates of "high-dose" clozapine therapy for treatment-refractory schizophrenia. |
2001-08-09 |
2023-08-12 |
Not clear |