| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Raaska, P J Neuvone. Ciprofloxacin increases serum clozapine and N-desmethylclozapine: a study in patients with schizophrenia. European journal of clinical pharmacology. vol 56. issue 8. 2001-02-15. PMID:11151749. |
ciprofloxacin increases serum clozapine and n-desmethylclozapine: a study in patients with schizophrenia. |
2001-02-15 |
2023-08-12 |
Not clear |
| K Raaska, P J Neuvone. Ciprofloxacin increases serum clozapine and N-desmethylclozapine: a study in patients with schizophrenia. European journal of clinical pharmacology. vol 56. issue 8. 2001-02-15. PMID:11151749. |
a possible pharmacokinetic interaction between a cyp1a2 inhibitor, ciprofloxacin, and clozapine was studied in schizophrenia patients with stable clozapine treatment. |
2001-02-15 |
2023-08-12 |
Not clear |
| K Wahlbeck, M Cheine, K Tuisku, A Ahokas, G Joffe, R Rimó. Risperidone versus clozapine in treatment-resistant schizophrenia: a randomized pilot study. Progress in neuro-psychopharmacology & biological psychiatry. vol 24. issue 6. 2001-02-08. PMID:11041534. |
risperidone versus clozapine in treatment-resistant schizophrenia: a randomized pilot study. |
2001-02-08 |
2023-08-12 |
human |
| K Wahlbeck, M Cheine, K Tuisku, A Ahokas, G Joffe, R Rimó. Risperidone versus clozapine in treatment-resistant schizophrenia: a randomized pilot study. Progress in neuro-psychopharmacology & biological psychiatry. vol 24. issue 6. 2001-02-08. PMID:11041534. |
the atypical antipsychotic risperidone may constitute an alternative to clozapine, the current treatment of choice for refractory schizophrenia. |
2001-02-08 |
2023-08-12 |
human |
| C J Hong, Y W Yu, C H Lin, H L Song, H C Lai, K H Yang, S J Tsa. Association study of apolipoprotein E epsilon4 with clinical phenotype and clozapine response in schizophrenia. Neuropsychobiology. vol 42. issue 4. 2001-02-02. PMID:11096331. |
association study of apolipoprotein e epsilon4 with clinical phenotype and clozapine response in schizophrenia. |
2001-02-02 |
2023-08-12 |
Not clear |
| C J Hong, Y W Yu, C H Lin, H L Song, H C Lai, K H Yang, S J Tsa. Association study of apolipoprotein E epsilon4 with clinical phenotype and clozapine response in schizophrenia. Neuropsychobiology. vol 42. issue 4. 2001-02-02. PMID:11096331. |
the present study tested the hypothesis that the apoe epsilon4 allele confers association with the clinical manifestations of schizophrenia or clozapine response. |
2001-02-02 |
2023-08-12 |
Not clear |
| Dossenbach MRK, J N Beuzen, M Avnon, R H Belmaker, A Elizur, M Mark, H Munitz, M Schneidman, D Shoshani, P Kratky, S L Grundy, G D Tollefso. The effectiveness of olanzapine in treatment-refractory schizophrenia when patients are nonresponsive to or unable to tolerate clozapine. Clinical therapeutics. vol 22. issue 9. 2001-02-01. PMID:11048902. |
the effectiveness of olanzapine in treatment-refractory schizophrenia when patients are nonresponsive to or unable to tolerate clozapine. |
2001-02-01 |
2023-08-12 |
Not clear |
| Dossenbach MRK, J N Beuzen, M Avnon, R H Belmaker, A Elizur, M Mark, H Munitz, M Schneidman, D Shoshani, P Kratky, S L Grundy, G D Tollefso. The effectiveness of olanzapine in treatment-refractory schizophrenia when patients are nonresponsive to or unable to tolerate clozapine. Clinical therapeutics. vol 22. issue 9. 2001-02-01. PMID:11048902. |
this multicenter, open-label study was designed to assess the efficacy and tolerability of olanzapine in patients with chronic schizophrenia who are resistant to therapy with classic neuroleptic agents and are either not responsive to or unable to tolerate clozapine. |
2001-02-01 |
2023-08-12 |
Not clear |
| J A Cramer, R Rosenheck, W Xu, J Thomas, W Henderson, D S Charne. Quality of life in schizophrenia: a comparison of instruments. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Schizophrenia bulletin. vol 26. issue 3. 2001-01-26. PMID:10993404. |
department of veterans affairs cooperative study group on clozapine in refractory schizophrenia. |
2001-01-26 |
2023-08-12 |
Not clear |
| J A Cramer, R Rosenheck, W Xu, J Thomas, W Henderson, D S Charne. Quality of life in schizophrenia: a comparison of instruments. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Schizophrenia bulletin. vol 26. issue 3. 2001-01-26. PMID:10993404. |
four hundred and twenty-three inpatients with schizophrenia participating in a clinical trial comparing clozapine and haloperidol (va cooperative study in health services #17) were evaluated using multiple measures of health-related quality of life (lehman quality of life interview; heinrichs-carpenter-hanlon quality of life scale; strauss-carpenter level of function scale, and clinical response.) |
2001-01-26 |
2023-08-12 |
Not clear |
| J P Lindenmaye. Treatment refractory schizophrenia. The Psychiatric quarterly. vol 71. issue 4. 2001-01-18. PMID:11025914. |
the effects of the atypicals clozapine, olanzapine, risperidone and quetiapine as compared to typicals are reviewed using available double-blind studies in this treatment refractory group of schizophrenia patients. |
2001-01-18 |
2023-08-12 |
Not clear |
| V Knott, A Labelle, B Jones, C Mahone. EEG hemispheric asymmetry as a predictor and correlate of short-term response to clozapine treatment in schizophrenia. Clinical EEG (electroencephalography). vol 31. issue 3. 2001-01-03. PMID:10923202. |
eeg hemispheric asymmetry as a predictor and correlate of short-term response to clozapine treatment in schizophrenia. |
2001-01-03 |
2023-08-12 |
Not clear |
| J T Birkett, M J Arranz, J Munro, S Osbourn, R W Kerwin, D A Collie. Association analysis of the 5-HT5A gene in depression, psychosis and antipsychotic response. Neuroreport. vol 11. issue 9. 2000-12-22. PMID:10884063. |
we conclude that allelic variation in the human 5-ht5a receptor gene may be involved in susceptibility to schizophrenia and affective disorders but not in determining response to clozapine. |
2000-12-22 |
2023-08-12 |
human |
| H Remschmidt, C Fleischhaker, K Hennighausen, E Schul. Management of schizophrenia in children and adolescents. The role of clozapine. Paediatric drugs. vol 2. issue 4. 2000-12-22. PMID:10946414. |
there are more than 15 studies that have also demonstrated the antipsychotic efficacy of clozapine in childhood and adolescent schizophrenia. |
2000-12-22 |
2023-08-12 |
Not clear |
| A Fink-Jense. Novel pharmacological approaches to the treatment of schizophrenia. Danish medical bulletin. vol 47. issue 3. 2000-11-30. PMID:10913983. |
these results are in accordance with the reported beneficial effects of clozapine, risperidone and sertindole on negative symptoms of schizophrenia and their lower degree of motoric side effects compared to haloperidol. |
2000-11-30 |
2023-08-12 |
human |
| A Fink-Jense. Novel pharmacological approaches to the treatment of schizophrenia. Danish medical bulletin. vol 47. issue 3. 2000-11-30. PMID:10913983. |
also these results are in concordance with the clinical effects of clozapine, risperidone, sertindole and haloperidol and support the hypothesis that reduced dopaminergic tone in the prefrontal cortex relates to the negative symptoms of schizophrenia. |
2000-11-30 |
2023-08-12 |
human |
| C A Buscema, Q A Abbasi, D J Barry, T H Lauv. An algorithm for the treatment of schizophrenia in the correctional setting: the Forensic Algorithm Project. The Journal of clinical psychiatry. vol 61. issue 10. 2000-11-30. PMID:11078038. |
the algorithm begins with any antipsychotic medication and proceeds to atypical neuroleptic usage, augmentation with other psychotropic agents, and, finally, the use of clozapine as the common pathway for refractory schizophrenia. |
2000-11-30 |
2023-08-12 |
Not clear |
| A Breier, R W Buchanan, D Irish, W T Carpente. Clozapine treatment of outpatients with schizophrenia: outcome and long-term response patterns. 1993. Psychiatric services (Washington, D.C.). vol 51. issue 10. 2000-11-07. PMID:11013322. |
clozapine treatment of outpatients with schizophrenia: outcome and long-term response patterns. |
2000-11-07 |
2023-08-12 |
Not clear |
| S M Dursun, A Szemis, H Andrews, P Whitaker, M A Revele. Effects of clozapine and typical antipsychotic drugs on plasma 5-HT turnover and impulsivity in patients with schizophrenia: a cross-sectional study. Journal of psychiatry & neuroscience : JPN. vol 25. issue 4. 2000-11-07. PMID:11022399. |
effects of clozapine and typical antipsychotic drugs on plasma 5-ht turnover and impulsivity in patients with schizophrenia: a cross-sectional study. |
2000-11-07 |
2023-08-12 |
Not clear |
| S A Chong, G Remingto. Clozapine augmentation: safety and efficacy. Schizophrenia bulletin. vol 26. issue 2. 2000-11-03. PMID:10885641. |
while clozapine has been demonstrated to be efficacious in refractory schizophrenia and possibly schizoaffective as well as bipolar disorders, a substantial number of patients still remain unresponsive. |
2000-11-03 |
2023-08-12 |
Not clear |