| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Rosenheck, J Cramer, E Allan, J Erdos, L K Frisman, W Xu, J Thomas, W Henderson, D Charne. Cost-effectiveness of clozapine in patients with high and low levels of hospital use. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Archives of general psychiatry. vol 56. issue 6. 1999-06-09. PMID:10359474. |
this study examined the relationship between pretreatment hospital use and the cost-effectiveness of clozapine in the treatment of refractory schizophrenia. |
1999-06-09 |
2023-08-12 |
Not clear |
| M Percudani, G Fattore, J Galletta, P L Mita, A Contini, A C Altamur. Health care costs of therapy-refractory schizophrenic patients treated with clozapine: a study in a community psychiatric service in Italy. Acta psychiatrica Scandinavica. vol 99. issue 4. 1999-06-01. PMID:10223430. |
this study evaluates the utilization of clozapine in the treatment of therapy-refractory schizophrenia in terms both of patterns of care and of health care costs in a community psychiatric service in italy. |
1999-06-01 |
2023-08-12 |
Not clear |
| A L Morera, P Barreiro, J L Cano-Muño. Risperidone and clozapine combination for the treatment of refractory schizophrenia. Acta psychiatrica Scandinavica. vol 99. issue 4. 1999-06-01. PMID:10223435. |
risperidone and clozapine combination for the treatment of refractory schizophrenia. |
1999-06-01 |
2023-08-12 |
Not clear |
| A L Morera, P Barreiro, J L Cano-Muño. Risperidone and clozapine combination for the treatment of refractory schizophrenia. Acta psychiatrica Scandinavica. vol 99. issue 4. 1999-06-01. PMID:10223435. |
clozapine is the most widely used antipsychotic drug for the treatment of refractory schizophrenia. |
1999-06-01 |
2023-08-12 |
Not clear |
| A C Tschen, M J Rieder, L K Oyewumi, D J Freema. The cytotoxicity of clozapine metabolites: implications for predicting clozapine-induced agranulocytosis. Clinical pharmacology and therapeutics. vol 65. issue 5. 1999-05-27. PMID:10340918. |
therapy of schizophrenia with clozapine is associated with the unpredictable development of severe neutropenia and agranulocytosis in 1% to 2% of patients. |
1999-05-27 |
2023-08-12 |
Not clear |
| C H Lin, S J Tsai, Y W Yu, H L Song, P C Tu, C B Sim, C P Hsu, K H Yang, C J Hon. No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population. Neuroreport. vol 10. issue 1. 1999-05-25. PMID:10094133. |
no evidence for association of serotonin-2a receptor variant (102t/c) with schizophrenia or clozapine response in a chinese population. |
1999-05-25 |
2023-08-12 |
human |
| C H Lin, S J Tsai, Y W Yu, H L Song, P C Tu, C B Sim, C P Hsu, K H Yang, C J Hon. No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population. Neuroreport. vol 10. issue 1. 1999-05-25. PMID:10094133. |
the serotonin hypothesis in schizophrenia had regained interest with the superior efficacy of clozapine in the refractory schizophrenic patients. |
1999-05-25 |
2023-08-12 |
human |
| C H Lin, S J Tsai, Y W Yu, H L Song, P C Tu, C B Sim, C P Hsu, K H Yang, C J Hon. No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population. Neuroreport. vol 10. issue 1. 1999-05-25. PMID:10094133. |
previous studies on the association between a silent mutation polymorphism of the 5ht2a gene (102t/c) and schizophrenia or clozapine response have yielded conflicting findings. |
1999-05-25 |
2023-08-12 |
human |
| C H Lin, S J Tsai, Y W Yu, H L Song, P C Tu, C B Sim, C P Hsu, K H Yang, C J Hon. No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population. Neuroreport. vol 10. issue 1. 1999-05-25. PMID:10094133. |
therefore, we investigated whether these genetic variants of the 5ht2a receptor are associated with schizophrenia or with response to clozapine treatment in a chinese population. |
1999-05-25 |
2023-08-12 |
human |
| C M Canuso, M B Goldma. Clozapine restores water balance in schizophrenic patients with polydipsia-hyponatremia syndrome. The Journal of neuropsychiatry and clinical neurosciences. vol 11. issue 1. 1999-05-20. PMID:9990561. |
clozapine appears to be the first effective pharmacotherapy for severe water imbalance in schizophrenia. |
1999-05-20 |
2023-08-12 |
human |
| A Inoue, Y Nakat. [How do antipsychotics exert their effects on dopamine receptor subtypes?]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 112. issue 6. 1999-05-17. PMID:10202760. |
recent evidences from studies on the effects of novel antipsychotic drugs such as clozapine on neurotransmitter receptors are prompting reconsideration of the dopaminergic hypothesis of schizophrenia. |
1999-05-17 |
2023-08-12 |
rat |
| D C Goff, D C Henderson, A E Evins, E Amic. A placebo-controlled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia. Biological psychiatry. vol 45. issue 4. 1999-05-13. PMID:10071726. |
a placebo-controlled crossover trial of d-cycloserine added to clozapine in patients with schizophrenia. |
1999-05-13 |
2023-08-12 |
Not clear |
| S Sous. Refractory schizophrenia: what works pharmacologically? Journal of psychosocial nursing and mental health services. vol 37. issue 2. 1999-05-12. PMID:10023603. |
clozaril is the only antipsychotic medication proven to be effective in treating refractory schizophrenia. |
1999-05-12 |
2023-08-12 |
Not clear |
| S Sous. Refractory schizophrenia: what works pharmacologically? Journal of psychosocial nursing and mental health services. vol 37. issue 2. 1999-05-12. PMID:10023603. |
nurses can be very instrumental in working with resistant systems, treating clinicians, and patients by recommending clozaril therapy for refractory schizophrenia. |
1999-05-12 |
2023-08-12 |
Not clear |
| M Bürg. [Clozapine and obsessive-compulsive symptoms in schizophrenia. A case history of one patient]. Der Nervenarzt. vol 70. issue 1. 1999-04-29. PMID:10087519. |
[clozapine and obsessive-compulsive symptoms in schizophrenia. |
1999-04-29 |
2023-08-12 |
Not clear |
| G Facciolà, A Avenoso, E Spina, E Perucc. Inducing effect of phenobarbital on clozapine metabolism in patients with chronic schizophrenia. Therapeutic drug monitoring. vol 20. issue 6. 1999-04-27. PMID:9853978. |
inducing effect of phenobarbital on clozapine metabolism in patients with chronic schizophrenia. |
1999-04-27 |
2023-08-12 |
Not clear |
| G Facciolà, A Avenoso, E Spina, E Perucc. Inducing effect of phenobarbital on clozapine metabolism in patients with chronic schizophrenia. Therapeutic drug monitoring. vol 20. issue 6. 1999-04-27. PMID:9853978. |
the steady state plasma concentrations of clozapine and its two major metabolites, norclozapine and clozapine n-oxide, were compared in patients with schizophrenia treated with clozapine in combination with phenobarbital (n=7), and in control patients treated with clozapine alone (n=15). |
1999-04-27 |
2023-08-12 |
Not clear |
| M C Mahoney, B F Connolly, C M Smit. A clozapine overdose with markedly elevated serum levels. Journal of clinical pharmacology. vol 39. issue 1. 1999-04-27. PMID:9987706. |
clozapine (clozaril) is an atypical antipsychotic agent used to treat schizophrenia refractory to other pharmacological agents. |
1999-04-27 |
2023-08-12 |
Not clear |
| M Hummer, G Kemmler, M Kurz, I Kurzthaler, H Oberbauer, W W Fleischhacke. Sexual disturbances during clozapine and haloperidol treatment for schizophrenia. The American journal of psychiatry. vol 156. issue 4. 1999-04-21. PMID:10200746. |
sexual disturbances during clozapine and haloperidol treatment for schizophrenia. |
1999-04-21 |
2023-08-12 |
Not clear |
| M Hummer, G Kemmler, M Kurz, I Kurzthaler, H Oberbauer, W W Fleischhacke. Sexual disturbances during clozapine and haloperidol treatment for schizophrenia. The American journal of psychiatry. vol 156. issue 4. 1999-04-21. PMID:10200746. |
the aim of this study was to evaluate the frequency and course of sexual disturbances associated with clozapine and haloperidol and their potential influence on compliance with medication regimens in patients with schizophrenia. |
1999-04-21 |
2023-08-12 |
Not clear |