| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Y Meltze. Suicide and schizophrenia: clozapine and the InterSePT study. International Clozaril/Leponex Suicide Prevention Trial. The Journal of clinical psychiatry. vol 60 Suppl 12. 1999-06-24. PMID:10372612. |
suicide and schizophrenia: clozapine and the intersept study. |
1999-06-24 |
2023-08-12 |
Not clear |
| M Campbell, P I Young, D N Bateman, J M Smith, S H Thoma. The use of atypical antipsychotics in the management of schizophrenia. British journal of clinical pharmacology. vol 47. issue 1. 1999-06-18. PMID:10073734. |
most published evidence exists to support the use of clozapine, which has also been shown to be effective in schizophrenia refractory to conventional agents. |
1999-06-18 |
2023-08-12 |
Not clear |
| R D Strous, J K Patel, S Zimmet, A I Gree. Clozapine and paroxetine in the treatment of schizophrenia with obsessive-compulsive features. The American journal of psychiatry. vol 156. issue 6. 1999-06-16. PMID:10360153. |
clozapine and paroxetine in the treatment of schizophrenia with obsessive-compulsive features. |
1999-06-16 |
2023-08-12 |
Not clear |
| M A Lee, K Jayathilake, H Y Meltze. A comparison of the effect of clozapine with typical neuroleptics on cognitive function in neuroleptic-responsive schizophrenia. Schizophrenia research. vol 37. issue 1. 1999-06-10. PMID:10227103. |
a comparison of the effect of clozapine with typical neuroleptics on cognitive function in neuroleptic-responsive schizophrenia. |
1999-06-10 |
2023-08-12 |
Not clear |
| M A Lee, K Jayathilake, H Y Meltze. A comparison of the effect of clozapine with typical neuroleptics on cognitive function in neuroleptic-responsive schizophrenia. Schizophrenia research. vol 37. issue 1. 1999-06-10. PMID:10227103. |
clozapine has been reported to improve selected aspects of cognitive function in neuroleptic-resistant schizophrenia. |
1999-06-10 |
2023-08-12 |
Not clear |
| M A Lee, K Jayathilake, H Y Meltze. A comparison of the effect of clozapine with typical neuroleptics on cognitive function in neuroleptic-responsive schizophrenia. Schizophrenia research. vol 37. issue 1. 1999-06-10. PMID:10227103. |
in this study, we report the first direct comparison of the effect of clozapine and typical neuroleptic drugs on cognitive function in neuroleptic-responsive schizophrenia. |
1999-06-10 |
2023-08-12 |
Not clear |
| M A Lee, K Jayathilake, H Y Meltze. A comparison of the effect of clozapine with typical neuroleptics on cognitive function in neuroleptic-responsive schizophrenia. Schizophrenia research. vol 37. issue 1. 1999-06-10. PMID:10227103. |
sixty-four patients with recent onset, neuroleptic-responsive schizophrenia or schizoaffective disorder were randomly assigned to either clozapine (n = 35) or typical neuroleptics (n = 29) and followed for 12 months. |
1999-06-10 |
2023-08-12 |
Not clear |
| M A Lee, K Jayathilake, H Y Meltze. A comparison of the effect of clozapine with typical neuroleptics on cognitive function in neuroleptic-responsive schizophrenia. Schizophrenia research. vol 37. issue 1. 1999-06-10. PMID:10227103. |
these results suggest that clozapine is superior to typical neuroleptics in improving specific types of cognitive function in recent onset, neuroleptic-responsive schizophrenia. |
1999-06-10 |
2023-08-12 |
Not clear |
| R Rosenheck, J Cramer, E Allan, J Erdos, L K Frisman, W Xu, J Thomas, W Henderson, D Charne. Cost-effectiveness of clozapine in patients with high and low levels of hospital use. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Archives of general psychiatry. vol 56. issue 6. 1999-06-09. PMID:10359474. |
department of veterans affairs cooperative study group on clozapine in refractory schizophrenia. |
1999-06-09 |
2023-08-12 |
Not clear |
| R Rosenheck, J Cramer, E Allan, J Erdos, L K Frisman, W Xu, J Thomas, W Henderson, D Charne. Cost-effectiveness of clozapine in patients with high and low levels of hospital use. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Archives of general psychiatry. vol 56. issue 6. 1999-06-09. PMID:10359474. |
this study examined the relationship between pretreatment hospital use and the cost-effectiveness of clozapine in the treatment of refractory schizophrenia. |
1999-06-09 |
2023-08-12 |
Not clear |
| M Percudani, G Fattore, J Galletta, P L Mita, A Contini, A C Altamur. Health care costs of therapy-refractory schizophrenic patients treated with clozapine: a study in a community psychiatric service in Italy. Acta psychiatrica Scandinavica. vol 99. issue 4. 1999-06-01. PMID:10223430. |
this study evaluates the utilization of clozapine in the treatment of therapy-refractory schizophrenia in terms both of patterns of care and of health care costs in a community psychiatric service in italy. |
1999-06-01 |
2023-08-12 |
Not clear |
| A L Morera, P Barreiro, J L Cano-Muño. Risperidone and clozapine combination for the treatment of refractory schizophrenia. Acta psychiatrica Scandinavica. vol 99. issue 4. 1999-06-01. PMID:10223435. |
risperidone and clozapine combination for the treatment of refractory schizophrenia. |
1999-06-01 |
2023-08-12 |
Not clear |
| A L Morera, P Barreiro, J L Cano-Muño. Risperidone and clozapine combination for the treatment of refractory schizophrenia. Acta psychiatrica Scandinavica. vol 99. issue 4. 1999-06-01. PMID:10223435. |
clozapine is the most widely used antipsychotic drug for the treatment of refractory schizophrenia. |
1999-06-01 |
2023-08-12 |
Not clear |
| A C Tschen, M J Rieder, L K Oyewumi, D J Freema. The cytotoxicity of clozapine metabolites: implications for predicting clozapine-induced agranulocytosis. Clinical pharmacology and therapeutics. vol 65. issue 5. 1999-05-27. PMID:10340918. |
therapy of schizophrenia with clozapine is associated with the unpredictable development of severe neutropenia and agranulocytosis in 1% to 2% of patients. |
1999-05-27 |
2023-08-12 |
Not clear |
| C H Lin, S J Tsai, Y W Yu, H L Song, P C Tu, C B Sim, C P Hsu, K H Yang, C J Hon. No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population. Neuroreport. vol 10. issue 1. 1999-05-25. PMID:10094133. |
no evidence for association of serotonin-2a receptor variant (102t/c) with schizophrenia or clozapine response in a chinese population. |
1999-05-25 |
2023-08-12 |
human |
| C H Lin, S J Tsai, Y W Yu, H L Song, P C Tu, C B Sim, C P Hsu, K H Yang, C J Hon. No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population. Neuroreport. vol 10. issue 1. 1999-05-25. PMID:10094133. |
the serotonin hypothesis in schizophrenia had regained interest with the superior efficacy of clozapine in the refractory schizophrenic patients. |
1999-05-25 |
2023-08-12 |
human |
| C H Lin, S J Tsai, Y W Yu, H L Song, P C Tu, C B Sim, C P Hsu, K H Yang, C J Hon. No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population. Neuroreport. vol 10. issue 1. 1999-05-25. PMID:10094133. |
previous studies on the association between a silent mutation polymorphism of the 5ht2a gene (102t/c) and schizophrenia or clozapine response have yielded conflicting findings. |
1999-05-25 |
2023-08-12 |
human |
| C H Lin, S J Tsai, Y W Yu, H L Song, P C Tu, C B Sim, C P Hsu, K H Yang, C J Hon. No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population. Neuroreport. vol 10. issue 1. 1999-05-25. PMID:10094133. |
therefore, we investigated whether these genetic variants of the 5ht2a receptor are associated with schizophrenia or with response to clozapine treatment in a chinese population. |
1999-05-25 |
2023-08-12 |
human |
| C M Canuso, M B Goldma. Clozapine restores water balance in schizophrenic patients with polydipsia-hyponatremia syndrome. The Journal of neuropsychiatry and clinical neurosciences. vol 11. issue 1. 1999-05-20. PMID:9990561. |
clozapine appears to be the first effective pharmacotherapy for severe water imbalance in schizophrenia. |
1999-05-20 |
2023-08-12 |
human |
| A Inoue, Y Nakat. [How do antipsychotics exert their effects on dopamine receptor subtypes?]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 112. issue 6. 1999-05-17. PMID:10202760. |
recent evidences from studies on the effects of novel antipsychotic drugs such as clozapine on neurotransmitter receptors are prompting reconsideration of the dopaminergic hypothesis of schizophrenia. |
1999-05-17 |
2023-08-12 |
rat |