| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Péter Gaszner, Zoltán Makko. Clozapine maintenance therapy in schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 3. 2004-06-17. PMID:15093952. |
clozapine administered for long-term maintenance therapy was effective both in paranoid and in catatonic schizophrenia. |
2004-06-17 |
2023-08-12 |
Not clear |
| Rocco Zoccali, Maria Rosaria Muscatello, Diletta La Torre, Giovanni Malara, Andrea Canale, Domenico Crucitti, Concetta D'Arrigo, Edoardo Spin. Lack of a pharmacokinetic interaction between mirtazapine and the newer antipsychotics clozapine, risperidone and olanzapine in patients with chronic schizophrenia. Pharmacological research. vol 48. issue 4. 2004-06-16. PMID:12902213. |
lack of a pharmacokinetic interaction between mirtazapine and the newer antipsychotics clozapine, risperidone and olanzapine in patients with chronic schizophrenia. |
2004-06-16 |
2023-08-12 |
Not clear |
| Rocco Zoccali, Maria Rosaria Muscatello, Diletta La Torre, Giovanni Malara, Andrea Canale, Domenico Crucitti, Concetta D'Arrigo, Edoardo Spin. Lack of a pharmacokinetic interaction between mirtazapine and the newer antipsychotics clozapine, risperidone and olanzapine in patients with chronic schizophrenia. Pharmacological research. vol 48. issue 4. 2004-06-16. PMID:12902213. |
the effect of mirtazapine on steady-state plasma concentrations of the newer atypical antipsychotics clozapine, risperidone and olanzapine was investigated in 24 patients with chronic schizophrenia. |
2004-06-16 |
2023-08-12 |
Not clear |
| b' Agnieszka Basta-Kaim, Bogus\\xc5\\x82awa Budziszewska, Lucylla Jaworska-Feil, Monika Le\\xc5\\x9bkiewicz, Magdalena Tetich, Marta Kubera, Simon Scharpe, W\\xc5\\x82adys\\xc5\\x82aw Laso\\xc5\\x8. Opposite effects of clozapine and sulpiride on the lipopolysaccharide-induced inhibition of the GR-mediated gene transcription in fibroblast cells. Polish journal of pharmacology. vol 55. issue 6. 2004-06-15. PMID:14730115.' |
opposite effect of clozapine and sulpiride on lps action may result from their distinct effect on activity of some kinases involved in regulation of gr transcriptional function and may determine their utility in the treatment of schizophrenia with or without immune system activation. |
2004-06-15 |
2023-08-12 |
mouse |
| Marcus W Agelink, Ilker Kavuk, Ismail A. Clozapine with amisulpride for refractory schizophrenia. The American journal of psychiatry. vol 161. issue 5. 2004-06-03. PMID:15121665. |
clozapine with amisulpride for refractory schizophrenia. |
2004-06-03 |
2023-08-12 |
Not clear |
| Laura Dazzi, Emanuele Seu, Giulia Cherchi, Giovanni Biggi. Inhibition of stress-induced dopamine output in the rat prefrontal cortex by chronic treatment with olanzapine. Biological psychiatry. vol 55. issue 5. 2004-05-27. PMID:15023575. |
evidence suggests that treatment with the atypical antipsychotic drugs olanzapine or clozapine results in a superior amelioration of the anxious and depressive symptoms that accompany schizophrenia relative to therapy with classical antipsychotics such as haloperidol. |
2004-05-27 |
2023-08-12 |
rat |
| Lilly Schwieler, Göran Engberg, Sophie Erhard. Clozapine modulates midbrain dopamine neuron firing via interaction with the NMDA receptor complex. Synapse (New York, N.Y.). vol 52. issue 2. 2004-05-21. PMID:15034917. |
the inhibitory action of clozapine on vta da neurons may account for its beneficial effects in ameliorating symptoms of schizophrenia and may suggest further studies to investigate a role of the glycine site of the nmda receptor as a target for novel antipsychotics. |
2004-05-21 |
2023-08-12 |
rat |
| Stephen Layton, Martin Barbea. Generic replacement of clozapine: a simple decision model from a Canadian perspective. Current medical research and opinion. vol 20. issue 4. 2004-05-21. PMID:15119982. |
the difference at reported upon switching patients with schizophrenia from brand name to generic clozapine. |
2004-05-21 |
2023-08-12 |
Not clear |
| A Pérez Bravo, M A Puña. [Sleep disorders with antipsychotic drugs: based on one case with clozapine]. Actas espanolas de psiquiatria. vol 32. issue 2. 2004-05-11. PMID:15042472. |
clozapine is a widely used atypical neuroleptic in the treatment of schizophrenia; its effects on sleep have been poorly studied, sedation being one of its side effects. |
2004-05-11 |
2023-08-12 |
Not clear |
| Peter F Buckley, Jeffrey M Goldstein, Robin A Emsle. Efficacy and tolerability of quetiapine in poorly responsive, chronic schizophrenia. Schizophrenia research. vol 66. issue 2-3. 2004-05-04. PMID:15061246. |
with the notable exception of clozapine, there is at present insufficient information on the efficacy of atypical antipsychotic medications in patients with poorly responsive schizophrenia. |
2004-05-04 |
2023-08-12 |
Not clear |
| P Huezo-Diaz, M J Arranz, J Munro, S Osborne, A Makoff, R W Kerwin, J Austin, M O'Donova. An association study of the neurotensin receptor gene with schizophrenia and clozapine response. Schizophrenia research. vol 66. issue 2-3. 2004-05-04. PMID:15061255. |
an association study of the neurotensin receptor gene with schizophrenia and clozapine response. |
2004-05-04 |
2023-08-12 |
Not clear |
| Małgorzata Pietrasze. Significance of dysfunctional glutamatergic transmission for the development of psychotic symptoms. Polish journal of pharmacology. vol 55. issue 2. 2004-04-07. PMID:12926541. |
clozapine) also inhibit the effects of nmda antagonists; (3) postmortem and in vivo studies have revealed alterations in ionotropic glutamate receptors (nmda, ampa, ka) and their modulatory sites in schizophrenia; (4) compounds enhancing the function of nmda receptors potentiate the antipsychotic effects of neuroleptics in schizophrenic patients. |
2004-04-07 |
2023-08-12 |
Not clear |
| Shih-Jen Tsai, Chen-Jee Hong, Younger W-Y Yu, Ching-Hua Lin, Ling-Ling Li. No association of tumor necrosis factor alpha gene polymorphisms with schizophrenia or response to clozapine. Schizophrenia research. vol 65. issue 1. 2004-04-06. PMID:14623371. |
no association of tumor necrosis factor alpha gene polymorphisms with schizophrenia or response to clozapine. |
2004-04-06 |
2023-08-12 |
Not clear |
| Shih-Jen Tsai, Chen-Jee Hong, Younger W-Y Yu, Ching-Hua Lin, Ling-Ling Li. No association of tumor necrosis factor alpha gene polymorphisms with schizophrenia or response to clozapine. Schizophrenia research. vol 65. issue 1. 2004-04-06. PMID:14623371. |
tumor necrosis factor alpha (tnf-alpha), a potent immunomodulator and proinflammatory cytokine, has been implicated in schizophrenia pathogenesis and clozapine response. |
2004-04-06 |
2023-08-12 |
Not clear |
| Shih-Jen Tsai, Chen-Jee Hong, Younger W-Y Yu, Ching-Hua Lin, Ling-Ling Li. No association of tumor necrosis factor alpha gene polymorphisms with schizophrenia or response to clozapine. Schizophrenia research. vol 65. issue 1. 2004-04-06. PMID:14623371. |
the results of these investigations suggest that the tnf-alpha gene -308g/a variants do not play a major role in susceptibility to, clinical manifestations for, or clozapine response in, schizophrenia. |
2004-04-06 |
2023-08-12 |
Not clear |
| Alan S Bellack, Nina R Schooler, Stephen R Marder, John M Kane, Clayton H Brown, Ye Yan. Do clozapine and risperidone affect social competence and problem solving? The American journal of psychiatry. vol 161. issue 2. 2004-04-01. PMID:14754789. |
the purpose of this investigation was to evaluate the effects of clozapine and risperidone on social skill and problem solving in patients with schizophrenia. |
2004-04-01 |
2023-08-12 |
Not clear |
| Jefferson Becker, Irenio Gomes, Eduardo S Ghisolfi, Alice Schuch, Fernanda L Paula Ramos, João Arthur Ehlers, Daniel B Nora, Diogo R Lara, Jaderson C da Cost. Clozapine, but not typical antipsychotics, correct P50 suppression deficit in patients with schizophrenia. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 115. issue 2. 2004-03-22. PMID:14744582. |
clozapine, but not typical antipsychotics, correct p50 suppression deficit in patients with schizophrenia. |
2004-03-22 |
2023-08-12 |
human |
| Robert R Conley, Deanna L Kelly, Charles M Richardson, Carol A Tamminga, William T Carpente. The efficacy of high-dose olanzapine versus clozapine in treatment-resistant schizophrenia: a double-blind crossover study. Journal of clinical psychopharmacology. vol 23. issue 6. 2004-03-19. PMID:14624201. |
the efficacy of high-dose olanzapine versus clozapine in treatment-resistant schizophrenia: a double-blind crossover study. |
2004-03-19 |
2023-08-12 |
Not clear |
| Laurel A Townsend, Rahul Manchand. Gains in speeded information processing following clozapine treatment of schizophrenia. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 49. issue 1. 2004-03-09. PMID:14763687. |
gains in speeded information processing following clozapine treatment of schizophrenia. |
2004-03-09 |
2023-08-12 |
Not clear |
| Jan Volavka, Pal Czobor, Thomas B Cooper, Brian Sheitman, Jean-Pierre Lindenmayer, Leslie Citrome, Joseph P McEvoy, Jeffrey A Lieberma. Prolactin levels in schizophrenia and schizoaffective disorder patients treated with clozapine, olanzapine, risperidone, or haloperidol. The Journal of clinical psychiatry. vol 65. issue 1. 2004-03-02. PMID:14744169. |
prolactin levels in schizophrenia and schizoaffective disorder patients treated with clozapine, olanzapine, risperidone, or haloperidol. |
2004-03-02 |
2023-08-12 |
Not clear |