| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Munro, P Matthiasson, S Osborne, M Travis, S Purcell, A M Cobb, M Launer, M D Beer, R Kerwi. Amisulpride augmentation of clozapine: an open non-randomized study in patients with schizophrenia partially responsive to clozapine. Acta psychiatrica Scandinavica. vol 110. issue 4. 2005-01-11. PMID:15352931. |
treatment options are very limited for individuals with schizophrenia resistant to clozapine. |
2005-01-11 |
2023-08-12 |
Not clear |
| Young-Chul Chung, Zhu Li, Jin Dai, Herbert Y Meltzer, Junji Ichikaw. Clozapine increases both acetylcholine and dopamine release in rat ventral hippocampus: role of 5-HT1A receptor agonism. Brain research. vol 1023. issue 1. 2004-12-21. PMID:15364019. |
atypical antipsychotic drugs (apds) such as clozapine, but not the typical apd haloperidol, improve some aspects of cognition in schizophrenia. |
2004-12-21 |
2023-08-12 |
rat |
| Young-Chul Chung, Zhu Li, Jin Dai, Herbert Y Meltzer, Junji Ichikaw. Clozapine increases both acetylcholine and dopamine release in rat ventral hippocampus: role of 5-HT1A receptor agonism. Brain research. vol 1023. issue 1. 2004-12-21. PMID:15364019. |
these differences may contribute, at least in part, to the superior ability of clozapine, compared to haloperidol, to improve cognition in schizophrenia. |
2004-12-21 |
2023-08-12 |
rat |
| Antonio Ciapparelli, Francesca Ducci, Claudia Carmassi, Marina Carlini, Rosemma Paggini, Mario Catena, Matteo Bottai, Liliana Dell'Oss. Predictors of response in a sample of treatment-resistant psychotic patients on clozapine. European archives of psychiatry and clinical neuroscience. vol 254. issue 5. 2004-12-20. PMID:15365711. |
this study aims at identifying potential predictors of clinical response and functional outcome in 101 neuroleptic-refractory patients with a dsm-iii-r diagnosis of schizophrenia (n = 34), schizoaffective disorder (n = 30) or bipolar disorder with psychotic features (n = 37), naturalistically treated with clozapine over a 48-month period. |
2004-12-20 |
2023-08-12 |
Not clear |
| Hubert H Fernandez, Joseph H Friedman, M Cecilia Lansang, Stewart A Factor, Eric S Molho, D Jim Cosku. Diabetes mellitus among parkinsonian patients treated chronically with clozapine. Parkinsonism & related disorders. vol 10. issue 7. 2004-12-20. PMID:15465403. |
there is accumulating data suggesting that clozapine may be associated with increased frequency of diabetes mellitus (dm) compared to conventional neuroleptic drugs in treating schizophrenia. |
2004-12-20 |
2023-08-12 |
human |
| Rafael Stryjer, Rael Strous, Faina Bar, Ginette Shaked, Roni Shiloh, Silvio Rozencwaig, Daniel Grupper, Nili Buchman, Moshe Kotler, J Martin Rabey, Abraham Weizma. Donepezil augmentation of clozapine monotherapy in schizophrenia patients: a double blind cross-over study. Human psychopharmacology. vol 19. issue 5. 2004-12-15. PMID:15252826. |
donepezil augmentation of clozapine monotherapy in schizophrenia patients: a double blind cross-over study. |
2004-12-15 |
2023-08-12 |
Not clear |
| Rafael Stryjer, Rael Strous, Faina Bar, Ginette Shaked, Roni Shiloh, Silvio Rozencwaig, Daniel Grupper, Nili Buchman, Moshe Kotler, J Martin Rabey, Abraham Weizma. Donepezil augmentation of clozapine monotherapy in schizophrenia patients: a double blind cross-over study. Human psychopharmacology. vol 19. issue 5. 2004-12-15. PMID:15252826. |
although this preliminary study failed to demonstrate a clear effect of donepezil augmentation in clozapine treated chronic schizophrenia patients, it seems that the subtle positive effect of donepezil observed in some of our patients should encourage further investigation in a larger sample of this patient subpopulation. |
2004-12-15 |
2023-08-12 |
Not clear |
| C Reist, C Mazzanti, R Vu, K Fujimoto, D Goldma. Inter-relationships of intermediate phenotypes for serotonin function, impulsivity, and a 5-HT2A candidate allele: His452Tyr. Molecular psychiatry. vol 9. issue 9. 2004-12-08. PMID:15037867. |
the 5-ht(2a) his452tyr polymorphism alters signal transduction, and has been associated with diminished efficacy of clozapine in schizophrenia. |
2004-12-08 |
2023-08-12 |
human |
| M Zink, E Mase, H Dressin. Combination of ziprasidone and clozapine in treatment-resistant schizophrenia. Human psychopharmacology. vol 19. issue 4. 2004-12-02. PMID:15181656. |
combination of ziprasidone and clozapine in treatment-resistant schizophrenia. |
2004-12-02 |
2023-08-12 |
Not clear |
| Zhiling Zhou, Xin Li, Kunyan Li, Zhihong Xie, Zeneng Cheng, Wenxin Peng, Feng Wang, Ronghua Zhu, Huande L. Simultaneous determination of clozapine, olanzapine, risperidone and quetiapine in plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 802. issue 2. 2004-11-29. PMID:15018785. |
clozapine (clz), olanzapine (olz), risperidone (rip) and quetiapine (qtp) have been widely used in the treatment of schizophrenia. |
2004-11-29 |
2023-08-12 |
Not clear |
| Ilana Kremer, Agnes Vass, Ielena Gorelik, Gali Bar, Monica Blanaru, Daniel C Javitt, Uriel Heresco-Lev. Placebo-controlled trial of lamotrigine added to conventional and atypical antipsychotics in schizophrenia. Biological psychiatry. vol 56. issue 6. 2004-11-08. PMID:15364042. |
recent studies suggest that when added to clozapine, lamotrigine treatment may result in significant positive symptoms reductions in schizophrenia. |
2004-11-08 |
2023-08-12 |
Not clear |
| Palmiero Monteleone, Michele Fabrazzo, Mariangela Serra, Alfonso Tortorella, M Giuseppina Pisu, Giovanni Biggio, Mario Ma. Long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and THDOC in patients with schizophrenia: a preliminary study. Journal of clinical psychopharmacology. vol 24. issue 4. 2004-11-04. PMID:15232336. |
long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and thdoc in patients with schizophrenia: a preliminary study. |
2004-11-04 |
2023-08-12 |
rat |
| J A Galvez-Buccollini, F Fiestas, P Herrera, J M Vega-Dienstmaier, B Guimas, G Mazzott. [Obsessive-compulsive symptoms in schizophrenia during treatment with clozapine and conventional antipsychotic drugs]. Actas espanolas de psiquiatria. vol 32. issue 4. 2004-10-12. PMID:15232749. |
[obsessive-compulsive symptoms in schizophrenia during treatment with clozapine and conventional antipsychotic drugs]. |
2004-10-12 |
2023-08-12 |
Not clear |
| Johannes Tauscher, Tabasum Hussain, Ofer Agid, N Paul L G Verhoeff, Alan A Wilson, Sylvain Houle, Gary Remington, Robert B Zipursky, Shitij Kapu. Equivalent occupancy of dopamine D1 and D2 receptors with clozapine: differentiation from other atypical antipsychotics. The American journal of psychiatry. vol 161. issue 9. 2004-10-07. PMID:15337652. |
clozapine, the prototype of atypical antipsychotics, remains unique in its efficacy in the treatment of refractory schizophrenia. |
2004-10-07 |
2023-08-12 |
Not clear |
| Philip S Wang, David A Ganz, Joshua S Benner, Robert J Glynn, Jerry Avor. Should clozapine continue to be restricted to third-line status for schizophrenia?: a decision-analytic model. The journal of mental health policy and economics. vol 7. issue 2. 2004-10-06. PMID:15208468. |
should clozapine continue to be restricted to third-line status for schizophrenia? |
2004-10-06 |
2023-08-12 |
Not clear |
| Douglas E Levy, A James O'Malley, Sharon-Lise T Norman. Covariate adjustment in clinical trials with non-ignorable missing data and non-compliance. Statistics in medicine. vol 23. issue 15. 2004-10-06. PMID:15273951. |
we then illustrate our findings in a study examining the efficacy of clozapine versus haloperidol in the treatment of refractory schizophrenia. |
2004-10-06 |
2023-08-12 |
Not clear |
| E M Tunbridge, D M Bannerman, T Sharp, P J Harriso. Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 23. 2004-09-24. PMID:15190105. |
the interaction between clozapine and tolcapone may have implications for the treatment of schizophrenia. |
2004-09-24 |
2023-08-12 |
human |
| Lous J A E Doude van Troostwijk, Richard P Koopmans, Hans D B Vermeulen, Henk-Jan Guchelaa. CYP1A2 activity is an important determinant of clozapine dosage in schizophrenic patients. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 20. issue 4-5. 2004-09-08. PMID:14659489. |
clozapine is an effective atypical antipsychotic drug applied in the treatment of resistant schizophrenia. |
2004-09-08 |
2023-08-12 |
Not clear |
| Chiao-Li Ke, Cheng-Fang Yen, Cheng-Chung Chen, Shang-Ju Yang, Weilun Chung, Ming-Jen Yan. Obsessive-compulsive symptoms associated with clozapine and risperidone treatment: three case reports and review of the literature. The Kaohsiung journal of medical sciences. vol 20. issue 6. 2004-08-31. PMID:15253471. |
we present three cases of schizophrenia in which distressing ocss occurred during clozapine or risperidone treatment. |
2004-08-31 |
2023-08-12 |
Not clear |
| R W Kerwin, Sarah Osborne, Ricardo Sainz-Fuerte. Heat stroke in schizophrenia during clozapine treatment: rapid recognition and management. Journal of psychopharmacology (Oxford, England). vol 18. issue 1. 2004-08-30. PMID:15107195. |
heat stroke in schizophrenia during clozapine treatment: rapid recognition and management. |
2004-08-30 |
2023-08-12 |
Not clear |