| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhiling Zhou, Xin Li, Kunyan Li, Zhihong Xie, Zeneng Cheng, Wenxin Peng, Feng Wang, Ronghua Zhu, Huande L. Simultaneous determination of clozapine, olanzapine, risperidone and quetiapine in plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 802. issue 2. 2004-11-29. PMID:15018785. |
clozapine (clz), olanzapine (olz), risperidone (rip) and quetiapine (qtp) have been widely used in the treatment of schizophrenia. |
2004-11-29 |
2023-08-12 |
Not clear |
| Ilana Kremer, Agnes Vass, Ielena Gorelik, Gali Bar, Monica Blanaru, Daniel C Javitt, Uriel Heresco-Lev. Placebo-controlled trial of lamotrigine added to conventional and atypical antipsychotics in schizophrenia. Biological psychiatry. vol 56. issue 6. 2004-11-08. PMID:15364042. |
recent studies suggest that when added to clozapine, lamotrigine treatment may result in significant positive symptoms reductions in schizophrenia. |
2004-11-08 |
2023-08-12 |
Not clear |
| Palmiero Monteleone, Michele Fabrazzo, Mariangela Serra, Alfonso Tortorella, M Giuseppina Pisu, Giovanni Biggio, Mario Ma. Long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and THDOC in patients with schizophrenia: a preliminary study. Journal of clinical psychopharmacology. vol 24. issue 4. 2004-11-04. PMID:15232336. |
long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and thdoc in patients with schizophrenia: a preliminary study. |
2004-11-04 |
2023-08-12 |
rat |
| J A Galvez-Buccollini, F Fiestas, P Herrera, J M Vega-Dienstmaier, B Guimas, G Mazzott. [Obsessive-compulsive symptoms in schizophrenia during treatment with clozapine and conventional antipsychotic drugs]. Actas espanolas de psiquiatria. vol 32. issue 4. 2004-10-12. PMID:15232749. |
[obsessive-compulsive symptoms in schizophrenia during treatment with clozapine and conventional antipsychotic drugs]. |
2004-10-12 |
2023-08-12 |
Not clear |
| Johannes Tauscher, Tabasum Hussain, Ofer Agid, N Paul L G Verhoeff, Alan A Wilson, Sylvain Houle, Gary Remington, Robert B Zipursky, Shitij Kapu. Equivalent occupancy of dopamine D1 and D2 receptors with clozapine: differentiation from other atypical antipsychotics. The American journal of psychiatry. vol 161. issue 9. 2004-10-07. PMID:15337652. |
clozapine, the prototype of atypical antipsychotics, remains unique in its efficacy in the treatment of refractory schizophrenia. |
2004-10-07 |
2023-08-12 |
Not clear |
| Philip S Wang, David A Ganz, Joshua S Benner, Robert J Glynn, Jerry Avor. Should clozapine continue to be restricted to third-line status for schizophrenia?: a decision-analytic model. The journal of mental health policy and economics. vol 7. issue 2. 2004-10-06. PMID:15208468. |
should clozapine continue to be restricted to third-line status for schizophrenia? |
2004-10-06 |
2023-08-12 |
Not clear |
| Douglas E Levy, A James O'Malley, Sharon-Lise T Norman. Covariate adjustment in clinical trials with non-ignorable missing data and non-compliance. Statistics in medicine. vol 23. issue 15. 2004-10-06. PMID:15273951. |
we then illustrate our findings in a study examining the efficacy of clozapine versus haloperidol in the treatment of refractory schizophrenia. |
2004-10-06 |
2023-08-12 |
Not clear |
| E M Tunbridge, D M Bannerman, T Sharp, P J Harriso. Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 23. 2004-09-24. PMID:15190105. |
the interaction between clozapine and tolcapone may have implications for the treatment of schizophrenia. |
2004-09-24 |
2023-08-12 |
human |
| Lous J A E Doude van Troostwijk, Richard P Koopmans, Hans D B Vermeulen, Henk-Jan Guchelaa. CYP1A2 activity is an important determinant of clozapine dosage in schizophrenic patients. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 20. issue 4-5. 2004-09-08. PMID:14659489. |
clozapine is an effective atypical antipsychotic drug applied in the treatment of resistant schizophrenia. |
2004-09-08 |
2023-08-12 |
Not clear |
| Chiao-Li Ke, Cheng-Fang Yen, Cheng-Chung Chen, Shang-Ju Yang, Weilun Chung, Ming-Jen Yan. Obsessive-compulsive symptoms associated with clozapine and risperidone treatment: three case reports and review of the literature. The Kaohsiung journal of medical sciences. vol 20. issue 6. 2004-08-31. PMID:15253471. |
we present three cases of schizophrenia in which distressing ocss occurred during clozapine or risperidone treatment. |
2004-08-31 |
2023-08-12 |
Not clear |
| R W Kerwin, Sarah Osborne, Ricardo Sainz-Fuerte. Heat stroke in schizophrenia during clozapine treatment: rapid recognition and management. Journal of psychopharmacology (Oxford, England). vol 18. issue 1. 2004-08-30. PMID:15107195. |
heat stroke in schizophrenia during clozapine treatment: rapid recognition and management. |
2004-08-30 |
2023-08-12 |
Not clear |
| R W Kerwin, Sarah Osborne, Ricardo Sainz-Fuerte. Heat stroke in schizophrenia during clozapine treatment: rapid recognition and management. Journal of psychopharmacology (Oxford, England). vol 18. issue 1. 2004-08-30. PMID:15107195. |
a case of heatstroke is reported in a 32-year-old man diagnosed with schizophrenia and on clozapine monotherapy. |
2004-08-30 |
2023-08-12 |
Not clear |
| Bruce J Kinon, Jonna Ahl, Virginia L Stauffer, Angela L Hill, Peter F Buckle. Dose response and atypical antipsychotics in schizophrenia. CNS drugs. vol 18. issue 9. 2004-08-23. PMID:15222776. |
limited data indicate that clozapine shows dose-related efficacy up to 600 mg/day in patients with treatment-resistant schizophrenia. |
2004-08-23 |
2023-08-12 |
Not clear |
| Ravi Kant, Ranjit Chalansani, K N Roy Chengappa, Mary F Dieringe. The off-label use of clozapine in adolescents with bipolar disorder, intermittent explosive disorder, or posttraumatic stress disorder. Journal of child and adolescent psychopharmacology. vol 14. issue 1. 2004-08-17. PMID:15142392. |
there are limited data in the literature regarding clozapine use in adolescents with diagnoses other than schizophrenia. |
2004-08-17 |
2023-08-12 |
Not clear |
| Deanna L Kelly, Robert R Conley, Charles M Richardson, Carol A Tamminga, William T Carpente. Adverse effects and laboratory parameters of high-dose olanzapine vs. clozapine in treatment-resistant schizophrenia. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 15. issue 3-4. 2004-08-10. PMID:14971863. |
adverse effects and laboratory parameters of high-dose olanzapine vs. clozapine in treatment-resistant schizophrenia. |
2004-08-10 |
2023-08-12 |
Not clear |
| Deanna L Kelly, Robert R Conley, Charles M Richardson, Carol A Tamminga, William T Carpente. Adverse effects and laboratory parameters of high-dose olanzapine vs. clozapine in treatment-resistant schizophrenia. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 15. issue 3-4. 2004-08-10. PMID:14971863. |
patients with treatment-resistant schizophrenia pose a major challenge to caregivers since only clozapine is documented as having superior efficacy in this population. |
2004-08-10 |
2023-08-12 |
Not clear |
| Mathias Zink, Udo Knopf, Fritz A Henn, Johannes Thom. Combination of clozapine and amisulpride in treatment-resistant schizophrenia--case reports and review of the literature. Pharmacopsychiatry. vol 37. issue 1. 2004-08-02. PMID:14750045. |
combination of clozapine and amisulpride in treatment-resistant schizophrenia--case reports and review of the literature. |
2004-08-02 |
2023-08-12 |
Not clear |
| I Reznik, I Yavin, R Stryjer, B Spivak, N Gonen, R Strous, R Mester, A Weizman, M Kotle. Clozapine in the treatment of obsessive-compulsive symptoms in schizophrenia patients: a case series study. Pharmacopsychiatry. vol 37. issue 2. 2004-08-02. PMID:15048611. |
clozapine in the treatment of obsessive-compulsive symptoms in schizophrenia patients: a case series study. |
2004-08-02 |
2023-08-12 |
Not clear |
| Jean Mary Zarate, Patricia Boksa, Trino Baptista, Ridha Joobe. Effects of clozapine on behavioral and metabolic traits relevant for schizophrenia in two mouse strains. Psychopharmacology. vol 171. issue 2. 2004-07-27. PMID:14615871. |
effects of clozapine on behavioral and metabolic traits relevant for schizophrenia in two mouse strains. |
2004-07-27 |
2023-08-12 |
mouse |
| Jean Mary Zarate, Patricia Boksa, Trino Baptista, Ridha Joobe. Effects of clozapine on behavioral and metabolic traits relevant for schizophrenia in two mouse strains. Psychopharmacology. vol 171. issue 2. 2004-07-27. PMID:14615871. |
in particular, patients with schizophrenia exhibit important variability in their therapeutic and metabolic responses to clozapine, an antipsychotic medication. |
2004-07-27 |
2023-08-12 |
mouse |