| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takashi Oide, Kunimasa Arima, Masashi Yamazaki, Norinao Hanyu, Shu-Ichi Iked. Coexistence of familial transthyretin amyloidosis ATTR Val30Met and spinocerebellar ataxia type 1 in a Japanese family--a follow-up autopsy report. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 11. issue 3. 2005-03-03. PMID:15523922. |
three brothers in a family with val30met transthyretin (ttr) amyloid polyneuropathy (fap) in iiyama, japan were studied pathologically. |
2005-03-03 |
2023-08-12 |
Not clear |
| Kristina Juneblad, Anna Näslund, Bert-Ove Olofsson, Ole B Suh. Outcome of exercise electrocardiography in familial amyloidotic polyneuropathy patients, Portuguese type, under evaluation for liver transplantation. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 11. issue 3. 2005-03-03. PMID:15523924. |
familial amyloidotic polyneuropathy (fap) is a dominantly inherited systemic amyloidosis caused by mutated transthyretin (ttr). |
2005-03-03 |
2023-08-12 |
Not clear |
| Claude Vital, Anne Vital, Sandrine Bouillot-Eimer, Christiane Brechenmacher, Xavier Ferrer, Alain Laguen. Amyloid neuropathy: a retrospective study of 35 peripheral nerve biopsies. Journal of the peripheral nervous system : JPNS. vol 9. issue 4. 2005-02-22. PMID:15574136. |
in 17 cases, amyloidosis was disclosed by pnb and 13 had a ttr pathology; eight of them, over 65 years old, correspond to a late-onset form of familial amyloid polyneuropathy which is an underdiagnosed condition. |
2005-02-22 |
2023-08-12 |
Not clear |
| Masaaki Nakamura, Yukio And. [Gene therapy in familial amyloidotic polyneuropathy by single-stranded oligonucleotides (SSOs)]. Rinsho byori. The Japanese journal of clinical pathology. vol 52. issue 10. 2005-02-15. PMID:15624495. |
transthyretin (ttr) related familial amyloidotic polyneuropathy (fap) is the common form of hereditary generalized amyloidosis and is characterized by the accumulation of amyloid deposits in the peripheral nerves and other organs. |
2005-02-15 |
2023-08-12 |
mouse |
| Pullakhandam Raghu, Bhattiprolu Sivakuma. Interactions amongst plasma retinol-binding protein, transthyretin and their ligands: implications in vitamin A homeostasis and transthyretin amyloidosis. Biochimica et biophysica acta. vol 1703. issue 1. 2005-01-28. PMID:15588697. |
misfolding and aggregation of ttr is implicated in amyloid disorders such as familial amyloid polyneuropathy (fap) and senile systemic amyloidosis (ssa). |
2005-01-28 |
2023-08-12 |
human |
| Andreas Busse, María A Sánchez, Victoria Monterroso, Marco V Alvarado, Pedro Leó. A severe form of amyloidotic polyneuropathy in a Costa Rican family with a rare transthyretin mutation (Glu54Lys). American journal of medical genetics. Part A. vol 128A. issue 2. 2005-01-12. PMID:15214015. |
a mutation search in the transthyretin (ttr) gene was performed seeking the cause of this severe form of familial amyloidotic polyneuropathy (fap). |
2005-01-12 |
2023-08-12 |
Not clear |
| H Koike, K Misu, M Sugiura, M Iijima, K Mori, M Yamamoto, N Hattori, E Mukai, Y Ando, S Ikeda, G Sobu. Pathology of early- vs late-onset TTR Met30 familial amyloid polyneuropathy. Neurology. vol 63. issue 1. 2004-12-21. PMID:15249622. |
pathology of early- vs late-onset ttr met30 familial amyloid polyneuropathy. |
2004-12-21 |
2023-08-12 |
Not clear |
| H Koike, K Misu, M Sugiura, M Iijima, K Mori, M Yamamoto, N Hattori, E Mukai, Y Ando, S Ikeda, G Sobu. Pathology of early- vs late-onset TTR Met30 familial amyloid polyneuropathy. Neurology. vol 63. issue 1. 2004-12-21. PMID:15249622. |
late-onset type i familial amyloid polyneuropathy (fap ttr met30) cases unrelated to endemic foci in japan show clinical features setting them apart from early-onset cases in endemic foci. |
2004-12-21 |
2023-08-12 |
Not clear |
| Maria Rosário Almeida, Bárbara Macedo, Isabel Cardoso, Isabel Alves, Gregorio Valencia, Gemma Arsequell, Antoni Planas, Maria João Saraiv. Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative. The Biochemical journal. vol 381. issue Pt 2. 2004-12-20. PMID:15080795. |
in familial amyloidotic polyneuropathy, ttr (transthyretin) variants are deposited as amyloid fibrils. |
2004-12-20 |
2023-08-12 |
Not clear |
| Miguel Luz Soares, Teresa Coelho, Alda Sousa, Gösta Holmgren, Maria João Saraiva, Daniel L Kastner, Joel N Buxbau. Haplotypes and DNA sequence variation within and surrounding the transthyretin gene: genotype-phenotype correlations in familial amyloid polyneuropathy (V30M) in Portugal and Sweden. European journal of human genetics : EJHG. vol 12. issue 3. 2004-11-06. PMID:14673473. |
familial amyloid polyneuropathy (fap) is a lethal autosomal dominant disorder in which fibrils derived from mutant forms of transthyretin (ttr), the normal plasma carrier of thyroxine (t(4)) and retinol-binding protein, are deposited in tissues. |
2004-11-06 |
2023-08-12 |
Not clear |
| Maria J Saraiv. Cellular consequences of transthyretin deposition. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 10 Suppl 1. 2004-09-13. PMID:14640036. |
mutant forms of transthyretin (ttr) deposit in tissues of patients presenting with familial amyloidotic polyneuropathy (fap). |
2004-09-13 |
2023-08-12 |
Not clear |
| Shu-ichi Ikeda, Yo-ichi Takei, Takahiko Tokuda, Masamitu Nakazato, Yukio And. Clinical and pathological findings of non-Val30Met TTR type familial amyloid polyneuropathy in Japan. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 10 Suppl 1. 2004-09-13. PMID:14640041. |
clinical and pathological findings of non-val30met ttr type familial amyloid polyneuropathy in japan. |
2004-09-13 |
2023-08-12 |
Not clear |
| Bo-Göran Ericzon, Marie Larsson, Gustaf Herlenius, Henryk E Wilcze. Report from the Familial Amyloidotic Polyneuropathy World Transplant Registry (FAPWTR) and the Domino Liver Transplant Registry (DLTR). Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 10 Suppl 1. 2004-09-13. PMID:14640044. |
familial amyloidotic polyneuropathy (fap) is a fatal disease, belonging to a group of systemic disorders caused by an amyloidogenic transthyretin (ttr) variant. |
2004-09-13 |
2023-08-12 |
Not clear |
| Takeshi Hattori, Yo-ichi Takei, Jun Koyama, Masamitsu Nakazato, Shu-ichi Iked. Clinical and pathological studies of cardiac amyloidosis in transthyretin type familial amyloid polyneuropathy. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 10. issue 4. 2004-09-07. PMID:14986482. |
to clarify the clinicopathological features of cardiac amyloidosis in transthyretin (ttr) familial amyloid polyneuropathy (fap), 169 patients were divided into three groups. |
2004-09-07 |
2023-08-12 |
Not clear |
| Maria João Saraiva, Mónica Mendes Sousa, Isabel Cardoso, Rui Fernande. Familial amyloidotic polyneuropathy: protein aggregation in the peripheral nervous system. Journal of molecular neuroscience : MN. vol 23. issue 1-2. 2004-09-01. PMID:15126690. |
we recently showed in vitro that ttr fibrils trigger nf-kappab activation, and subsequent studies identified some inflammatory and apoptotic pathways opening perspectives to understand the neurodegeneration process in familial amyloidotic polyneuropathy (fap). |
2004-09-01 |
2023-08-12 |
mouse |
| F Salvi, C Scaglione, R Michelucci, R P Linke, L Obici, A Ravani, P Rimessi, A Ferlini, S Meletti, T Cavallaro, C A Tassinari, P Martinell. Atypical familial motor neuropathy in patients with mutant TTR Ile68Leu. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 10. issue 3. 2004-07-29. PMID:14640031. |
the familial occurrence of axonal and slowly progressive polyneuropathy led us to consider these patients as candidates for ttr molecular analysis. |
2004-07-29 |
2023-08-12 |
Not clear |
| F Salvi, C Scaglione, R Michelucci, R P Linke, L Obici, A Ravani, P Rimessi, A Ferlini, S Meletti, T Cavallaro, C A Tassinari, P Martinell. Atypical familial motor neuropathy in patients with mutant TTR Ile68Leu. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 10. issue 3. 2004-07-29. PMID:14640031. |
the aims of this work are to report the possibility of a motor onset of amyloid polyneuropathy and to suggest the search for ttr mutations in familial cases of axonal polyneuropathy. |
2004-07-29 |
2023-08-12 |
Not clear |
| H Robert Bergen, Steven R Zeldenrust, Stephen Naylo. An on-line assay for clinical detection of amyloidogenic transthyretin variants directly from serum. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 10. issue 3. 2004-07-29. PMID:14640032. |
the assay should be an effective first line discriminator of patients who are being considered to have familial amyloidotic polyneuropathy (fap) and an adjunct to definitive diagnosis by sequencing of the ttr gene or protein. |
2004-07-29 |
2023-08-12 |
Not clear |
| Mónica M Sousa, José Ferrão, Rui Fernandes, António Guimarães, José B Geraldes, Rui Perdigoto, Luís Tomé, Oscar Mota, Luís Negrão, Alexandre Linhares Furtado, Maria João Saraiv. Deposition and passage of transthyretin through the blood-nerve barrier in recipients of familial amyloid polyneuropathy livers. Laboratory investigation; a journal of technical methods and pathology. vol 84. issue 7. 2004-07-29. PMID:15122304. |
familial amyloid polyneuropathy (fap) is characterized by deposition of mutated transthyretin (ttr) in the peripheral nervous system. |
2004-07-29 |
2023-08-12 |
Not clear |
| Klaus Altland, Pia Winter, Maria Joao M Saraiva, Ole Suh. Sulfite and base for the treatment of familial amyloidotic polyneuropathy: two additive approaches to stabilize the conformation of human amyloidogenic transthyretin. Neurogenetics. vol 5. issue 1. 2004-05-17. PMID:14534839. |
in this paper we demonstrate a stabilizing effect of sulfite on ttr tetramers from a familial amyloidotic polyneuropathy (fap) patient homozygous for the most-common amyloidogenic ttr-v30 m mutation. |
2004-05-17 |
2023-08-12 |
human |