All Relations between Neurodegenerative Diseases and apoptosis

Publication Sentence Publish Date Extraction Date Species
Qian Xu, Yi-Meng Zhao, Nai-Qi He, Rong Gao, Wen-Xin Xu, Xiu-Juan Zhuo, Zhong Ren, Chun-Yan Wu, Lu-Shan Li. PCSK9: A emerging participant in heart failure. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2022-12-19. PMID:36535197. aside from regulating lipid metabolism, pcsk9 may be involved in other biological processes such as apoptosis, autophagy, pyroptosis, inflammation, and tumor immunity and related to diabetes and neurodegenerative diseases. 2022-12-19 2023-08-14 human
Chang Liu, Rong J. Manganese-induced neuronal apoptosis: new insights into the role of endoplasmic reticulum stress in regulating autophagy-related proteins. Toxicological sciences : an official journal of the Society of Toxicology. 2022-12-15. PMID:36519822. here, our review focuses on discussing the existing mechanisms and connections between er stress, autophagy and apoptosis, which provide a new perspective on mn-induced neuronal apoptosis, and the pathogenesis of neurodegenerative diseases. 2022-12-15 2023-08-14 Not clear
Efthalia Angelopoulou, Efstratios-Stylianos Pyrgelis, Christina Piper. Emerging Potential of the Phosphodiesterase (PDE) Inhibitor Ibudilast for Neurodegenerative Diseases: An Update on Preclinical and Clinical Evidence. Molecules (Basel, Switzerland). vol 27. issue 23. 2022-12-11. PMID:36500540. the preclinical evidence shows that ibudilast may act neuroprotectively in neurodegenerative diseases, by suppressing neuroinflammation, inhibiting apoptosis, regulating the mitochondrial function and by affecting the ubiquitin-proteasome and autophagosome-lysosome pathways, as well as by attenuating oxidative stress. 2022-12-11 2023-08-14 Not clear
Ao Li, Qun Zhao, Linxi Chen, Zhiyue L. Apelin/APJ system: an emerging therapeutic target for neurological diseases. Molecular biology reports. 2022-11-15. PMID:36378421. also, apelin/apj system has therapeutic effects on chronic neurodegenerative disease models, involving the regulation of neurotrophic factors, neuroendocrine, oxidative stress, neuroinflammation, neuronal apoptosis, and autophagy. 2022-11-15 2023-08-14 Not clear
Hamad Ghaleb Daila. Potential of Therapeutic Small Molecules in Apoptosis Regulation in the Treatment of Neurodegenerative Diseases: An Updated Review. Molecules (Basel, Switzerland). vol 27. issue 21. 2022-11-11. PMID:36364033. potential of therapeutic small molecules in apoptosis regulation in the treatment of neurodegenerative diseases: an updated review. 2022-11-11 2023-08-14 Not clear
Frances Vivienne Armas, Amedeo D'Angiull. Neuroinflammation and Neurodegeneration of the Central Nervous System from Air Pollutants: A Scoping Review. Toxics. vol 10. issue 11. 2022-11-10. PMID:36355957. specifically, we focus on evidence on magnetic resonance imaging and neurodegenerative diseases, and the links between neuronal apoptosis and inflammation. 2022-11-10 2023-08-14 Not clear
Baoyi Chen, Wenting Zhang, Chuyuan Lin, Lingyun Zhan. A Comprehensive Review on Beneficial Effects of Catechins on Secondary Mitochondrial Diseases. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232871. it can also induce apoptosis and, eventually, multi-system damage, which leads to neurodegenerative disease. 2022-10-14 2023-08-14 Not clear
Ruo-Lan Li, Ling-Yu Wang, Hu-Xinyue Duan, Qing Zhang, Xiaohui Guo, Chunjie Wu, Wei Pen. Regulation of mitochondrial dysfunction induced cell apoptosis is a potential therapeutic strategy for herbal medicine to treat neurodegenerative diseases. Frontiers in pharmacology. vol 13. 2022-10-10. PMID:36210852. regulation of mitochondrial dysfunction induced cell apoptosis is a potential therapeutic strategy for herbal medicine to treat neurodegenerative diseases. 2022-10-10 2023-08-14 Not clear
Ruo-Lan Li, Ling-Yu Wang, Hu-Xinyue Duan, Qing Zhang, Xiaohui Guo, Chunjie Wu, Wei Pen. Regulation of mitochondrial dysfunction induced cell apoptosis is a potential therapeutic strategy for herbal medicine to treat neurodegenerative diseases. Frontiers in pharmacology. vol 13. 2022-10-10. PMID:36210852. therefore, in this review, we will focus on the potential therapeutic agents from herbal medicines for treating neurodegenerative diseases via suppressing apoptosis through regulation of mitochondrial dysfunction, in order to provide a foundation for the development of more candidate drugs for neurodegenerative diseases from herbal medicine. 2022-10-10 2023-08-14 Not clear
Shuji Wakatsuki, Toshiyuki Arak. Novel insights into the mechanism of reactive oxygen species-mediated neurodegeneration. Neural regeneration research. vol 18. issue 4. 2022-10-07. PMID:36204830. neurite degeneration, a major component of many neurodegenerative diseases, such as parkinson's disease, alzheimer's disease, and amyotrophic lateral sclerosis, is not part of the typical apoptosis signaling mechanism, but rather it appears that a self-destructive process is in action. 2022-10-07 2023-08-14 Not clear
Dewei He, Yanting Liu, Jie Li, Hefei Wang, Bojian Ye, Yuan He, Zhe Li, Xiyu Gao, Shoupeng Fu, Dianfeng Li. Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease. Cells. vol 11. issue 18. 2022-09-23. PMID:36139502. parkinson's disease (pd) is a neurodegenerative disease in which neuronal apoptosis and associated inflammation are involved in its pathogenesis. 2022-09-23 2023-08-14 mouse
Chaemoon Lim, Ao Xuan Zhen, Sungwoo Ok, Pincha Devage Sameera Madushan Fernando, Herath Mudiyanselage Udari Lakmini Herath, Mei Jing Piao, Kyoung Ah Kang, Jin Won Hyu. Hesperidin Protects SH-SY5Y Neuronal Cells against High Glucose-Induced Apoptosis via Regulation of MAPK Signaling. Antioxidants (Basel, Switzerland). vol 11. issue 9. 2022-09-23. PMID:36139782. neurodegenerative diseases are associated with neuronal cell death through apoptosis. 2022-09-23 2023-08-14 Not clear
Christian Ardianto, Robert Shen, Jimmy F A Barus, Poppy Kristina Sasmita, Yuda Turana, Lilis Lilis, Veronika Maria Sidhart. Secretome as neuropathology-targeted intervention of Parkinson's disease. Regenerative therapy. vol 21. 2022-09-12. PMID:36092507. parkinson's disease (pd) is the second most common progressive neurodegenerative disease, characterized by apoptosis of dopaminergic neurons in substansia nigra pars compacta (snpc) caused by ⍺-synuclein aggregation. 2022-09-12 2023-08-14 Not clear
Yongjie Xu, Haizhi Li, Gang Chen, Liying Zhu, Hairong Lin, Changyudong Huang, Sijia Wei, Tingting Yang, Wen Qian, Xing Li, Shuyun Zhao, Wei Pa. Radix polygoni multiflori protects against hippocampal neuronal apoptosis in diabetic encephalopathy by inhibiting the HDAC4/JNK pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 153. 2022-09-09. PMID:36076547. though the histone deacetylase 4 (hdac4), hdac5, hdac7, and hdac9 form class iia of the hdac superfamily have been found participating in multiple neurodegenerative diseases, while jnk signaling pathway activation was hypothesized as a key cause leading to cell apoptosis, the correlation between hdac4 and jnk signaling pathway remains unknown. 2022-09-09 2023-08-14 rat
Chenghe Fan, Yu Tian, Yilin Zhang, Junfang Teng, Xinyu Zha. Ceramide induces macrophage migration inhibitory factor -mediated parthanatos in mouse neurons by increasing ROS levels. Neuroscience letters. 2022-09-08. PMID:36075319. ceramides, the key component of sphingolipid metabolism and second messengers, have been associated with neurodegenerative diseases progression and pathology, and can induce neuronal apoptosis and necrosis, but the effect of ceramide on parthanatos has not been fully elucidated. 2022-09-08 2023-08-14 mouse
Sheikh Shohag, Shomaya Akhter, Shahidul Islam, Tonmoy Sarker, Moinuddin Khan Sifat, Md Mominur Rahman, Md Rezaul Islam, Rohit Sharm. Perspectives on the Molecular Mediators of Oxidative Stress and Antioxidant Strategies in the Context of Neuroprotection and Neurolongevity: An Extensive Review. Oxidative medicine and cellular longevity. vol 2022. 2022-09-05. PMID:36062188. when reactive oxygen species and antioxidants are in imbalance in our bodies, they can cause cell structure damage, neurodegenerative diseases, diabetes, hypercholesterolemia, atherosclerosis, cancer, cardiovascular diseases, metabolic disorders, and other obesity-related disorders, as well as protein misfolding, mitochondrial dysfunction, glial cell activation, and subsequent cellular apoptosis. 2022-09-05 2023-08-14 human
Ye Tao, Sean X Leng, Haiyan Zhan. Ketogenic diet: an effective treatment approach for neurodegenerative diseases. Current neuropharmacology. 2022-08-31. PMID:36043794. this review systematically summarizes the scientific literature supporting this effective treatment approach for neurodegenerative diseases, including effects on mitochondrial function, oxidative stress, neuronal apoptosis, neuroinflammation, and the microbiota-gut-brain axis. 2022-08-31 2023-08-14 Not clear
Chih-Hsiung Hsieh, Yi-Ching Wan. Emerging roles of plasma gelsolin in tumorigenesis and modulating the tumor microenvironment. The Kaohsiung journal of medical sciences. 2022-08-09. PMID:35942641. the protein expression of gelsolin, an actin scavenger controlling cytoskeletal remodeling, cell morphology, differentiation, movement, and apoptosis, has been found to be significantly decreased in several pathological conditions including neurodegenerative diseases, inflammatory disorders, and cancers. 2022-08-09 2023-08-14 Not clear
Shu-Chao Wang, Xi-Min Hu, Kun Xion. The regulatory role of Pin1 in neuronal death. Neural regeneration research. vol 18. issue 1. 2022-07-08. PMID:35799512. aside from the involvement of pin1 in the apoptosis that accompanies neurodegenerative diseases, accumulating evidence suggests that pin1 also plays a role in regulated necrosis and autophagy, thereby exhibiting distinct effects, including both neurotoxic and neuroprotective effects. 2022-07-08 2023-08-14 Not clear
Tim Bilbrough, Emanuele Piemontese, Oliver Seit. Dissecting the role of protein phosphorylation: a chemical biology toolbox. Chemical Society reviews. 2022-06-21. PMID:35726784. secondly, we showcase illustrative examples that applied these tools to answer biological questions pertaining to proteins involved in signal transduction, control of transcription, neurodegenerative diseases and aggregation, apoptosis and autophagy, and transmembrane proteins. 2022-06-21 2023-08-14 Not clear