| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong Yao, Yaping Yuan, Shuyan Sheng, Yifan Li, Xiaoniu Tang, Hao G. Observing astrocyte polarization in brains from mouse chronically infected with Toxoplasma gondii. Scientific reports. vol 14. issue 1. 2024-05-07. PMID:38714696. |
astrocyte polarization, particularly the a1 subtype associated with neuronal apoptosis, has been identified in various neurodegenerative diseases. |
2024-05-07 |
2024-05-27 |
mouse |
| Shuang Zhao, Guiling Mo, Qiang Wang, Jin Xu, Shihui Yu, Zhibin Huang, Wei Liu, Wenqing Zhan. Role of RB1 in neurodegenerative diseases: inhibition of post-mitotic neuronal apoptosis via Kmt5b. Cell death discovery. vol 10. issue 1. 2024-04-18. PMID:38637503. |
role of rb1 in neurodegenerative diseases: inhibition of post-mitotic neuronal apoptosis via kmt5b. |
2024-04-18 |
2024-04-21 |
human |
| Shuang Zhao, Guiling Mo, Qiang Wang, Jin Xu, Shihui Yu, Zhibin Huang, Wei Liu, Wenqing Zhan. Role of RB1 in neurodegenerative diseases: inhibition of post-mitotic neuronal apoptosis via Kmt5b. Cell death discovery. vol 10. issue 1. 2024-04-18. PMID:38637503. |
dysregulation of neuronal apoptosis can lead to neurodegenerative diseases. |
2024-04-18 |
2024-04-21 |
human |
| Hidenori Homma, Hikari Tanaka, Kyota Fujita, Hitoshi Okazaw. Necrosis Links Neurodegeneration and Neuroinflammation in Neurodegenerative Disease. International journal of molecular sciences. vol 25. issue 7. 2024-04-13. PMID:38612448. |
apoptosis was previously considered to be the only mechanism of neuronal cell death in neurodegenerative diseases. |
2024-04-13 |
2024-04-15 |
Not clear |
| Linnet Bischof, Franziska Schweitzer, Jürgen J Heinisc. Functional Conservation of the Small GTPase Rho5/Rac1-A Tale of Yeast and Men. Cells. vol 13. issue 6. 2024-03-27. PMID:38534316. |
malfunctions in this context affect cellular plasticity and apoptosis, related to neurodegenerative diseases and diabetes. |
2024-03-27 |
2024-03-29 |
human |
| Mohamed J Saadh, Ahmed Faisal, Mohaned Adil, Rahman S Zabibah, Abdurakhmon Mamatkulovich Mamadaliev, Mahmood Jasem Jawad, Fahad Alsaikhan, Bagher Farhoo. Parkinson's Disease and MicroRNAs: A Duel Between Inhibition and Stimulation of Apoptosis in Neuronal Cells. Molecular neurobiology. 2024-03-23. PMID:38520611. |
in that context, targeting apoptosis appears as a promising therapeutic approach for treating neurodegenerative diseases. |
2024-03-23 |
2024-03-26 |
Not clear |
| Mohamed J Saadh, Ahmed Faisal, Mohaned Adil, Rahman S Zabibah, Abdurakhmon Mamatkulovich Mamadaliev, Mahmood Jasem Jawad, Fahad Alsaikhan, Bagher Farhoo. Parkinson's Disease and MicroRNAs: A Duel Between Inhibition and Stimulation of Apoptosis in Neuronal Cells. Molecular neurobiology. 2024-03-23. PMID:38520611. |
non-coding rnas-more especially, micrornas, or mirnas-are a promising target for the therapy of neurodegenerative diseases because they are essential for a number of cellular processes, including signaling, apoptosis, cell proliferation, and gene regulation. |
2024-03-23 |
2024-03-26 |
Not clear |
| Evgenii D Kryl'skii, Grigorii A Razuvaev, Tatyana N Popova, Sergei A Oleinik, Svetlana M Medvedeva, Khidmet S Shikhalie. 6-Hydroxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline Demonstrates Neuroprotective Properties in Experimental Parkinson's Disease by Enhancing the Antioxidant System, Normalising Chaperone Activity and Suppressing Apoptosis. Neurochemical research. 2024-03-19. PMID:38502411. |
parkinson's disease (pd) is a neurodegenerative disease, whereby disturbances within the antioxidant defence system, increased aggregation of proteins, and activation of neuronal apoptosis all have a crucial role in the pathogenesis. |
2024-03-19 |
2024-03-23 |
rat |
| Siva Prasad Panda, Adarsh Kesharwani, Samaresh Datta, D S N B K Prasanth, Sunil Kumar Panda, Ajay Gur. JAK2/STAT3 as a new potential target to manage neurodegenerative diseases: An interactive review. European journal of pharmacology. 2024-03-16. PMID:38492876. |
neurodegenerative diseases (ndds) are a collection of incapacitating disorders in which neuroinflammation and neuronal apoptosis are major pathological consequences due to oxidative stress. |
2024-03-16 |
2024-03-19 |
human |
| Beatrice Silvestri, Michela Mochi, Darilang Mawrie, Valeria de Turris, Alessio Colantoni, Beatrice Borhy, Margherita Medici, Eric Nathaniel Anderson, Maria Giovanna Garone, Christopher Patrick Zammerilla, Udai Bhan Pandey, Alessandro Ros. HuD (ELAVL4) gain-of-function impairs neuromuscular junctions and induces apoptosis in bioRxiv : the preprint server for biology. 2024-03-11. PMID:38464028. |
hud (elavl4) gain-of-function impairs neuromuscular junctions and induces apoptosis in early defects at the neuromuscular junction (nmj) are among the first hallmarks of the progressive neurodegenerative disease amyotrophic lateral sclerosis (als). |
2024-03-11 |
2024-03-14 |
Not clear |
| Huiyong Zheng, Qiang Liu, Siwei Zhou, Hongliang Luo, Wenjun Zhan. Role and therapeutic targets of P2X7 receptors in neurodegenerative diseases. Frontiers in immunology. vol 15. 2024-02-19. PMID:38370420. |
when neurodegenerative diseases result in neuronal apoptosis and necrosis, atp activates the p2x7r. |
2024-02-19 |
2024-02-21 |
Not clear |
| Hamidreza Poortalebi, Mahta ZareDini, Sima Foroughi-Nematollahi, Tahereh Farkhondeh, Saeed Samarghandian, Mohammad Hossein Pourhanife. Therapeutic Effect of Resveratrol and its Novel Formulations on Lung Cancer: Focus on Biological Aspects and Underlying Pathways. Current medicinal chemistry. 2024-02-02. PMID:38303533. |
it has shown therapeutic potetial in various diseases including neurodegenerative diseases, cardiovascular disorders, and cancers through the regulation of key cellular signaling such as apoptosis, as well as molecular pathways such as microrna modulation. |
2024-02-02 |
2024-02-04 |
Not clear |
| Sahar Golpour- Hamedani, Makan Pourmasoumi, Sudiyeh Hejri Zarifi, Gholamreza Askari, Tannaz Jamialahmadi, Mohammad Bagherniya, Amirhossein Sahebka. Therapeutic effects of saffron and its components on neurodegenerative diseases. Heliyon. vol 10. issue 2. 2024-02-01. PMID:38298664. |
saffron and its compounds can play an important role in inhibiting neuroinflammation and excitotoxic pathways, modulating autophagy and apoptosis, attenuating oxidative damage, and activating defensive antioxidant enzymes, resulting in neuroprotection against neurodegenerative diseases. |
2024-02-01 |
2024-02-03 |
human |
| Kohei Sone, Asami Mori, Kenji Sakamoto, Tsutomu Nakahar. The Role of microRNAs Related to Apoptosis for International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38256177. |
apoptosis is one of the common mechanisms leading to neuronal death in many neurodegenerative diseases, including glaucoma. |
2024-01-23 |
2024-01-25 |
Not clear |
| Ziping He, Qianqian Chen, Kaiyue Wang, Jiang Lin, Yilin Peng, Jinlong Zhang, Xisheng Yan, Yan Ji. Single-cell transcriptomics analysis of cellular heterogeneity and immune mechanisms in neurodegenerative diseases. The European journal of neuroscience. 2024-01-15. PMID:38221677. |
neurodegenerative diseases are identified by the abnormal apoptosis of neurons in the brain with few or no effective therapy strategies at present, which has been a growing healthcare concern and brought a great burden to society. |
2024-01-15 |
2024-01-17 |
Not clear |
| Mohamed A El-Emam, Eman Sheta, Hanan S El-Abhar, Dalaal M Abdallah, Ahmed M El Kerdawy, Wagdy M Eldehna, Mennatallah A Gowaye. Morin suppresses mTORc1/IRE-1α/JNK and IP3R-VDAC-1 pathways: Crucial mechanisms in apoptosis and mitophagy inhibition in experimental Huntington's disease, supported by in silico molecular docking simulations. Life sciences. 2023-12-23. PMID:38141855. |
endoplasmic reticulum stress (ers) with aberrant mitochondrial-er contact (merc), mitophagy, and apoptosis are interconnected determinants in neurodegenerative diseases. |
2023-12-23 |
2023-12-25 |
Not clear |
| Yong-Gang Fan, Ting-Yao Wu, Ling-Xiao Zhao, Rong-Jun Jia, Hang Ren, Wen-Jia Hou, Zhan-You Wan. From zinc homeostasis to disease progression: Unveiling the neurodegenerative puzzle. Pharmacological research. 2023-12-20. PMID:38123108. |
disruptions in zinc levels can impact the survival and activity of neurons, thereby contributing to the progression of neurodegenerative diseases through mechanisms like cell apoptosis regulation, protein phase separation, ferroptosis, oxidative stress, and neuroinflammation. |
2023-12-20 |
2023-12-23 |
human |
| Mehrdad Valizadeh, Ehsan Derafsh, Fahimeh Abdi Abyaneh, Sayedeh Kiana Parsamatin, Fatemeh Zahra Rashidi Noshabad, Azam Alinaghipour, Zahra Yaghoobi, Abdolkarim Talebi Taheri, Ehsan Dadgostar, Michael Aschner, Hamed Mirzaei, Omid Reza Tamtaji, Fatemeh Nabavizade. Non-Coding RNAs and Neurodegenerative Diseases: Information of their Roles in Apoptosis. Molecular neurobiology. 2023-12-15. PMID:38102518. |
non-coding rnas and neurodegenerative diseases: information of their roles in apoptosis. |
2023-12-15 |
2023-12-18 |
Not clear |
| Yiwen Bao, Lufeng Wang, Hong Liu, Jie Yang, Fei Yu, Can Cui, Dongya Huan. A Diagnostic Model for Parkinson's Disease Based on Anoikis-Related Genes. Molecular neurobiology. 2023-11-24. PMID:38001358. |
parkinson's disease (pd) is the second most prevalent neurodegenerative disease, and its pathological mechanisms are thought to be closely linked to apoptosis. |
2023-11-24 |
2023-11-28 |
human |
| Sadia Anjum, Hamile Ali, Faiza Naseer, Maisa S Abduh, Halima Qadir, Salik Kakar, Yasir Waheed, Tahir Ahma. Antioxidant activity of Carica papaya & Persea americana fruits against cadmium induced neurotoxicity, nephrotoxicity, and hepatotoxicity in rats with a computational approach. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 81. 2023-11-09. PMID:37944220. |
cadmium is widely reported to interfere with the proper functioning of cells by disrupting cellular redox balance, causing apoptosis, and leading to hepatocellular damage, neurotoxicity, pulmonary edema, cancer, and cardiac and neurodegenerative diseases. |
2023-11-09 |
2023-11-20 |
rat |