Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Christian Franceschini, Fabio Pizza, Francesca Cavalli, Giuseppe Plazz. A practical guide to the pharmacological and behavioral therapy of Narcolepsy. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 18. issue 1. 2021-07-30. PMID:33886090. |
narcolepsy is a rare, chronic, and disabling central nervous system hypersomnia; two forms can be recognized: narcolepsy type 1 (nt1) and narcolepsy type 2 (nt2). |
2021-07-30 |
2023-08-13 |
Not clear |
Birgitte Rahbek Kornu. Narcolepsy Type I as an autoimmune disorder. Handbook of clinical neurology. vol 181. 2021-07-28. PMID:34238455. |
narcolepsy type 1 (nt1) is hypothesized to be an autoimmune disease targeting the hypocretin/orexin neurons in the lateral hypothalamus. |
2021-07-28 |
2023-08-13 |
Not clear |
M Järvelä, V Raatikainen, A Kotila, J Kananen, V Korhonen, L Q Uddin, H Ansakorpi, V Kiviniem. Lag Analysis of Fast fMRI Reveals Delayed Information Flow Between the Default Mode and Other Networks in Narcolepsy. Cerebral cortex communications. vol 1. issue 1. 2021-07-24. PMID:34296133. |
in this study, we used fast fmri data to analyze dynamics of inter resting-state network (rsn) information signaling between narcolepsy type 1 patients (nt1, |
2021-07-24 |
2023-08-13 |
Not clear |
Chenyang Li, Karen Spruyt, Chi Zhang, Yuhua Zuo, Shaomei Shang, Xiaosong Dong, Hui Ouyang, Jun Zhang, Fang Ha. Reliability and validity of the Chinese version of Narcolepsy Severity Scale in adult patients with narcolepsy type 1. Sleep medicine. vol 81. 2021-07-05. PMID:33640842. |
to evaluate reliability and validity of the chinese version of narcolepsy severity scale (nss) in adult patients with narcolepsy type 1 (nt1). |
2021-07-05 |
2023-08-13 |
Not clear |
Axel Bornstein, Anders Hedström, Pontus Waslin. Actigraphy measurement of physical activity and energy expenditure in narcolepsy type 1, narcolepsy type 2 and idiopathic hypersomnia: A Sensewear Armband study. Journal of sleep research. vol 30. issue 2. 2021-06-25. PMID:32281246. |
the cause of obesity in narcolepsy type 1 (nt1) patients is not fully understood. |
2021-06-25 |
2023-08-13 |
Not clear |
Christian Franceschini, Chiara Fante, Maria Claudia Folli, Maria Filosa, Fabio Pizza, Elena Antelmi, Francesca Ingravallo, Giuseppe Plazz. Giving a voice to cataplectic experience: recollections from patients with narcolepsy type 1. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 16. issue 4. 2021-06-23. PMID:32022668. |
the objective of this study was to assess the narratives from the recalled accounts of cataplexy attacks of patients with narcolepsy type 1 (nt1). |
2021-06-23 |
2023-08-13 |
Not clear |
Bei Huang, Tao Xu, Zongwen Wang, Kun Chen, Jihui Zhang, Zhongxin Zhao, Jianhua Zhuang, Huijuan W. The clinical characteristics of cataplectic attack in narcolepsy type 1. Sleep medicine. vol 77. 2021-06-21. PMID:31607435. |
this study was conducted to clarify the clinical characteristics of cataplexy by staging, and to further analyse the correlations of clinical features and cataplectic stages in patients with narcolepsy type 1 (nt1). |
2021-06-21 |
2023-08-13 |
Not clear |
Agata Gabryelska, Bartosz Szmyd, Emily L Maschauer, Amber Roguski, Robyn Canham, Ian Morrison, Piotr Białasiewicz, Renata L Rih. Utility of measuring CSF hypocretin-1 level in patients with suspected narcolepsy. Sleep medicine. vol 71. 2021-06-21. PMID:32492554. |
the patho-aetiology of narcolepsy type i (nt1) is the loss of hypocretin-1 secreting neurons in the hypothalamus. |
2021-06-21 |
2023-08-13 |
Not clear |
Qidi Ding, Jing Li, Fulong Xiao, Chi Zhang, Xiaosong Dong, Fang Ha. Anti-streptococcal antibodies in Chinese patients with type -1 narcolepsy. Sleep medicine. vol 72. 2021-06-21. PMID:32540635. |
narcolepsy type 1 (nt1) is considered to be an autoimmune disease, and streptococcal infection may be an environmental trigger. |
2021-06-21 |
2023-08-13 |
Not clear |
Berit Hjelde Hansen, Hilde T Juvodden, Sebjørg Hesla Nordstrand, Rannveig Viste, Per M Thorsby, David Swanson, Kristian B Nilsen, Terje Nærland, Stine Knudsen-Heie. High prevalence of ADHD symptoms in unmedicated youths with post-H1N1 narcolepsy type 1. Sleep medicine. vol 75. 2021-06-21. PMID:32858357. |
to characterize attention deficit-hyperactivity disorder (adhd) symptoms in unmedicated post-h1n1 narcolepsy type 1 (nt1) youths, and explore associations between adhd symptoms and the narcolepsy phenotype. |
2021-06-21 |
2023-08-13 |
Not clear |
Anelia Dietmann, Michael P Horn, Mink S Schinkelshoek, Rolf Fronczek, Anke Salmen, Panagiotis Bargiotas, Gert J Lammers, Ramin Khatami, Claudio L A Bassett. Conventional autoantibodies against brain antigens are not routinely detectable in serum and CSF of narcolepsy type 1 and 2 patients. Sleep medicine. vol 75. 2021-06-21. PMID:32858359. |
narcolepsy with cataplexy (nt1) is a chronic hypothalamic disorder with a presumed immune-mediated etiology leading to a loss of hypocretin neurons. |
2021-06-21 |
2023-08-13 |
Not clear |
Anelia Dietmann, Michael P Horn, Mink S Schinkelshoek, Rolf Fronczek, Anke Salmen, Panagiotis Bargiotas, Gert J Lammers, Ramin Khatami, Claudio L A Bassett. Conventional autoantibodies against brain antigens are not routinely detectable in serum and CSF of narcolepsy type 1 and 2 patients. Sleep medicine. vol 75. 2021-06-21. PMID:32858359. |
a total of 86 patients with primary/idiopathic narcolepsy (74 nt1, 12 nt2) and 23 control patients with excessive daytime sleepiness due to other causes were tested for the presence of a wide range of anti-neuronal antibodies in both serum and cerebrospinal fluid (csf). |
2021-06-21 |
2023-08-13 |
Not clear |
Megumi Hazumi, Wakako Ito, Ryo Okubo, Masataka Wada, Makoto Hond. Development and validation of the hypersomnia-specific beliefs scale. Sleep medicine. vol 75. 2021-06-21. PMID:32862014. |
patients with central hypersomnia, especially narcolepsy type 1 and idiopathic hypersomnia (nt1 and ihs) often have psychological frustration in their daily lives. |
2021-06-21 |
2023-08-13 |
Not clear |
Anelia Dietmann, Camilla Gallino, Elena Wenz, Johannes Mathis, Claudio L A Bassett. Multiple sleep latency test and polysomnography in patients with central disorders of hypersomnolence. Sleep medicine. vol 79. 2021-06-21. PMID:33453460. |
we retrospectively analyzed electrophysiological data from mslt and psg in 370 consecutive patients with narcolepsy type 1 (nt1, n = 97), type 2 (nt2, n = 31), idiopathic hypersomnia (ih, n = 48), nonorganic hypersomnia (noh, n = 116) and insufficient sleep syndrome (iss, n = 78). |
2021-06-21 |
2023-08-13 |
Not clear |
Helena Backlund Wasling, Axel Bornstein, Pontus Waslin. Quality of life and procrastination in post-H1N1 narcolepsy, sporadic narcolepsy and idiopathic hypersomnia, a Swedish cross-sectional study. Sleep medicine. vol 76. 2021-06-15. PMID:33152582. |
a cross-sectional study of health-related quality of life (hrqol), procrastination and the relation to sleepiness, depression and fatigue in post-h1n1 narcolepsy type 1 (nt1), sporadic nt1 and idiopathic hypersomnia (ih). |
2021-06-15 |
2023-08-13 |
Not clear |
Serena Scarpelli, Valentina Alfonsi, Anita D'Anselmo, Maurizio Gorgoni, Alessandro Musetti, Giuseppe Plazzi, Luigi De Gennaro, Christian Franceschin. Dream Activity in Narcoleptic Patients During the COVID-19 Lockdown in Italy. Frontiers in psychology. vol 12. 2021-06-15. PMID:34122276. |
some studies highlighted that patients with narcolepsy type-1 (nt1) experience high lucid dream frequency, and this phenomenon has been associated with a creative personality. |
2021-06-15 |
2023-08-13 |
human |
Christian Franceschini, Fabio Pizza, Elena Antelmi, Maria Claudia Folli, Giuseppe Plazz. Narcolepsy treatment: pharmacological and behavioral strategies in adults and children. Sleep & breathing = Schlaf & Atmung. vol 24. issue 2. 2021-06-10. PMID:31290083. |
narcolepsy is a disabling, rare, and chronic sleep disorder, currently classified as distinct central nervous system hypersomnia in narcolepsy type 1 (nt1) and narcolepsy type 2 (nt2). |
2021-06-10 |
2023-08-13 |
Not clear |
Christian Franceschini, Fabio Pizza, Elena Antelmi, Maria Claudia Folli, Giuseppe Plazz. Narcolepsy treatment: pharmacological and behavioral strategies in adults and children. Sleep & breathing = Schlaf & Atmung. vol 24. issue 2. 2021-06-10. PMID:31290083. |
although today a reliable pathogenic hypothesis identifies the cause of nt1 as an autoimmune process destroying hypocretin-producing cells, there is no cure for narcolepsy, and the symptomatic pharmacological available treatments are not entirely effective for all symptoms. |
2021-06-10 |
2023-08-13 |
Not clear |
Chiara Berteotti, Viviana Lo Martire, Sara Alvente, Stefano Bastianini, Cristiano Bombardi, Gabriele Matteoli, Hiroshi Ohtsu, Jian-Sheng Lin, Alessandro Silvani, Giovanna Zoccol. Orexin/Hypocretin and Histamine Cross-Talk on Hypothalamic Neuron Counts in Mice. Frontiers in neuroscience. vol 15. 2021-06-08. PMID:34093114. |
the loss of hypothalamic neurons that produce wake-promoting orexin (hypocretin) neuropeptides is responsible for narcolepsy type 1 (nt1). |
2021-06-08 |
2023-08-13 |
mouse |
Andreas Brink-Kjaer, Julie A E Christensen, Matteo Cesari, Emmanuel Mignot, Helge B D Sorensen, Poul Jennu. Cortical arousal frequency is increased in narcolepsy type 1. Sleep. vol 44. issue 5. 2021-05-21. PMID:33249455. |
hypocretin deficient narcolepsy (type 1, nt1) presents with multiple sleep abnormalities including sleep-onset rapid eye movement (rem) periods (soremps) and sleep fragmentation. |
2021-05-21 |
2023-08-13 |
human |