| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chuan Hong, Noel J Byrne, Beata Zamlynny, Srivanya Tummala, Li Xiao, Jennifer M Shipman, Andrea T Partridge, Christina Minnick, Michael J Breslin, Michael T Rudd, Shawn J Stachel, Vanessa L Rada, Jeffrey C Kern, Kira A Armacost, Scott A Hollingsworth, Julie A O'Brien, Dawn L Hall, Terrence P McDonald, Corey Strickland, Alexei Brooun, Stephen M Soisson, Kaspar Hollenstei. Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation. Nature communications. vol 12. issue 1. 2021-02-17. PMID:33547286. |
narcolepsy type 1 (nt1) is a chronic neurological disorder that impairs the brain's ability to control sleep-wake cycles. |
2021-02-17 |
2023-08-13 |
Not clear |
| Elena Antelmi, Fabio Pizza, Christian Franceschini, Raffaele Ferri, Giuseppe Plazz. REM sleep behavior disorder in narcolepsy: A secondary form or an intrinsic feature? Sleep medicine reviews. vol 50. 2021-02-08. PMID:31931470. |
rbd reportedly affects 30-60% of patients with narcolepsy type 1 (nt1), but it may be seen also in narcolepsy type 2 (nt2). |
2021-02-08 |
2023-08-13 |
Not clear |
| Emanuela Postiglione, Fabio Pizza, Francesca Ingravallo, Luca Vignatelli, Marco Filardi, Anastasia Mangiaruga, Elena Antelmi, Monica Moresco, Claudia Oriolo, Uberto Pagotto, Giuseppe Plazz. Impact of COVID-19 pandemic lockdown on narcolepsy type 1 management. Brain and behavior. vol 11. issue 1. 2021-02-08. PMID:33247632. |
narcolepsy type 1 (nt1) is a chronic rare hypersomnia of central origin requiring a combination of behavioral and pharmacological treatments. |
2021-02-08 |
2023-08-13 |
Not clear |
| Elena Antelmi, Marco Filardi, Fabio Pizza, Stefano Vandi, Monica Moresco, Christian Franceschini, Michele Tinazzi, Raffaele Ferri, Giuseppe Plazz. REM Sleep Behavior Disorder in Children With Type 1 Narcolepsy Treated With Sodium Oxybate. Neurology. vol 96. issue 2. 2021-01-27. PMID:33177222. |
to study the effect of stable treatment with sodium oxybate (so) on nocturnal rem sleep behavior disorder (rbd) and rem sleep without atonia (rswa) that severely affected children with type 1 narcolepsy (nt1). |
2021-01-27 |
2023-08-13 |
Not clear |
| Gaia Pellitteri, Pierluigi Dolso, Mariarosaria Valente, Gian Luigi Gigl. Orgasmolepsy in Narcolepsy Type 1 Responsive to Pitolisant: A Case Report. Nature and science of sleep. vol 12. 2021-01-11. PMID:33408544. |
we describe a case of a young male patient with narcolepsy type 1 (nt1), who developed generalized cataplexy attacks during sexual intercourses, on which we have obtained a satisfactory control with pitolisant. |
2021-01-11 |
2023-08-13 |
Not clear |
| Carlo Cipolli, Fabio Pizza, Claudia Bellucci, Michela Mazzetti, Giovanni Tuozzi, Stefano Vandi, Giuseppe Plazz. Dream Generation and Recall in Daytime NREM Sleep of Patients With Narcolepsy Type 1. Frontiers in neuroscience. vol 14. 2020-12-18. PMID:33328876. |
the less rigid architecture of sleep in patients with narcolepsy type 1 (nt1) compared with healthy subjects may provide new insights into some unresolved issues of dream experience (de), under the assumption that their de frequencies are comparable. |
2020-12-18 |
2023-08-13 |
human |
| Mahmoud M A Abulmeaty, Ahmed S BaHammam, Ghadeer S Aljuraiban, Ali M Almajwal, Mona S Aldosar. Measured resting metabolic rate, respiratory quotient, and body composition in patients with narcolepsy: a preliminary report of a case-control study. Scientific reports. vol 10. issue 1. 2020-12-08. PMID:32620831. |
the narcolepsy patients were subdivided into two subgroups (n = 7/each): those with cataplexy (nt1) and those without cataplexy (nt2). |
2020-12-08 |
2023-08-13 |
Not clear |
| Mahmoud M A Abulmeaty, Ahmed S BaHammam, Ghadeer S Aljuraiban, Ali M Almajwal, Mona S Aldosar. Measured resting metabolic rate, respiratory quotient, and body composition in patients with narcolepsy: a preliminary report of a case-control study. Scientific reports. vol 10. issue 1. 2020-12-08. PMID:32620831. |
these findings give an insight into the distinctive state of altered metabolism in patients with narcolepsy, especially the resting metabolic rate, which was not altered in nt1 vs. nt2 compared to the controls when matched for bmi, age, and gender. |
2020-12-08 |
2023-08-13 |
Not clear |
| Lucie Barateau, Régis Lopez, Sofiene Chenini, Carole Pesenti, Anna Laura Rassu, Isabelle Jaussent, Yves Dauvillier. Depression and suicidal thoughts in untreated and treated narcolepsy: Systematic analysis. Neurology. vol 95. issue 20. 2020-12-04. PMID:32963102. |
to assess the frequency and determinants of depressive symptoms and suicidal thoughts in adults with narcolepsy type 1 (nt1) and controls, as well as the changes after nt1 management and the risk factors of major depressive episode (mde) and suicide risk (sr) in nt1. |
2020-12-04 |
2023-08-13 |
Not clear |
| Marco Filardi, Nurhak Demir, Fabio Pizza, Stefano Vandi, Elena Antelmi, Silvia Noce, Oliviero Bruni, Giuseppe Plazz. Prevalence and neurophysiological correlates of sleep disordered breathing in pediatric type 1 narcolepsy. Sleep medicine. vol 65. 2020-10-26. PMID:31706191. |
to investigate the prevalence and neurophysiological correlates of obstructive sleep disordered breathing (osa) in type 1 narcolepsy (nt1) children and adolescents. |
2020-10-26 |
2023-08-13 |
Not clear |
| Yves Dauvilliers, Elisa Evangelista, Delphine de Verbizier, Lucie Barateau, Philippe Peigneu. [18F]Fludeoxyglucose-Positron Emission Tomography Evidence for Cerebral Hypermetabolism in the Awake State in Narcolepsy and Idiopathic Hypersomnia. Frontiers in neurology. vol 8. 2020-10-01. PMID:28775709. |
we compared relative changes in regional brain metabolism in two central hypersomnia conditions with different clinical features, namely narcolepsy type 1 (nt1) and ih, and in healthy controls. |
2020-10-01 |
2023-08-13 |
Not clear |
| Justin Chin, Craig Bearison, Nanette Silverberg, Mary Lee Won. Concomitant atopic dermatitis and narcolepsy type 1: psychiatric implications and challenges in management. General psychiatry. vol 32. issue 5. 2020-10-01. PMID:31673678. |
atopic dermatitis (ad) and narcolepsy type 1 (nt1) are two distinct diseases that have not been classically shown to be related. |
2020-10-01 |
2023-08-13 |
human |
| Andrew C Cogswell, Kiran Maski, Thomas E Scammell, Dominique Tucker, Zachary S Orban, Igor J Koralni. Children with Narcolepsy type 1 have increased T-cell responses to orexins. Annals of clinical and translational neurology. vol 6. issue 12. 2020-10-01. PMID:31730293. |
narcolepsy type 1 (nt1) is caused by severe loss of the orexin neurons, and is highly associated with hla dqb1*06:02. |
2020-10-01 |
2023-08-13 |
Not clear |
| Silvia Leiva, Jimena Madrazo, Claudio Podest. Narcolepsy with cataplexy and hyperthyroidism sudden appeared after H1N1 vaccination. Sleep science (Sao Paulo, Brazil). vol 11. issue 1. 2020-09-30. PMID:29796199. |
narcolepsy type 1 (nt1) is a chronic sleep disorder, characterized by excessive daytime sleepiness, cataplexy and fragmented nocturnal sleep. |
2020-09-30 |
2023-08-13 |
Not clear |
| Taku Miyagawa, Katsushi Tokunag. Genetics of narcolepsy. Human genome variation. vol 6. 2020-09-30. PMID:30652006. |
currently, narcolepsy is subdivided into two types according to the international classification of sleep disorders, 3rd edition: narcolepsy type 1 (nt1) and narcolepsy type 2 (nt2). |
2020-09-30 |
2023-08-13 |
human |
| Lucie Barateau, Yves Dauvillier. Recent advances in treatment for narcolepsy. Therapeutic advances in neurological disorders. vol 12. 2020-09-30. PMID:31632459. |
narcolepsy type 1 (nt1) is a chronic orphan disorder, caused by the selective and irreversible loss of hypocretin/orexin (orx) neurons, by a probable autoimmune process. |
2020-09-30 |
2023-08-13 |
Not clear |
| Aljohara S Almeneessier, Nouf S Alballa, Budoor H Alsalman, Salih Aleissi, Awad H Olaish, Ahmed S BaHamma. A 10-Year Longitudinal Observational Study Of Cataplexy In A Cohort Of Narcolepsy Type 1 Patients. Nature and science of sleep. vol 11. 2020-09-28. PMID:31695532. |
narcolepsy type 1 (nt1) is thought to have a chronic persistent course. |
2020-09-28 |
2023-08-13 |
Not clear |
| Maria Pia Giannoccaro, Giombattista Sallemi, Rocco Liguori, Giuseppe Plazzi, Fabio Pizz. Immunotherapy in Narcolepsy. Current treatment options in neurology. vol 22. issue 1. 2020-09-28. PMID:31997035. |
narcolepsy type 1 (nt1) is a chronic and disabling sleep disorder due to the loss of hypocretinergic neurons in the lateral hypothalamus pathophysiologically linked to an autoimmune process. |
2020-09-28 |
2023-08-13 |
Not clear |
| Christian Franceschini, Chiara Fante, Marco Filardi, Maria Claudia Folli, Francesca Brazzi, Fabio Pizza, Anita D'Anselmo, Francesca Ingravallo, Elena Antelmi, Giuseppe Plazz. Can a Peer Support the Process of Self-Management in Narcolepsy? A Qualitative Narrative Analysis of a Narcoleptic Patient. Frontiers in psychology. vol 11. 2020-09-28. PMID:32733314. |
narcolepsy type 1 (nt1) is a chronic and rare sleep disorder typically arising during adolescence and young adulthood. |
2020-09-28 |
2023-08-13 |
Not clear |
| Kjetil Bårdsen, Michaela D Gjerstad, Markku Partinen, Ingeborg Kvivik, Anne Bolette Tjensvoll, Peter Ruoff, Roald Omdal, Cato Bred. Considerably Lower Levels of Hypocretin-1 in Cerebrospinal Fluid Is Revealed by a Novel Mass Spectrometry Method Compared with Standard Radioimmunoassay. Analytical chemistry. vol 91. issue 14. 2020-09-25. PMID:31260261. |
low levels of hypocretin-1 (hcrt1) in cerebrospinal fluid (csf) are associated with narcolepsy type 1 (nt1). |
2020-09-25 |
2023-08-13 |
human |