Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Alexander Lind, Ilaria Marzinotto, Cristina Brigatti, Anita Ramelius, Lorenzo Piemonti, Vito Lampason. A/H1N1 hemagglutinin antibodies show comparable affinity in vaccine-related Narcolepsy type 1 and control and are unlikely to contribute to pathogenesis. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33603024. |
an increased incidence of narcolepsy type 1 (nt1) was observed in scandinavia following the 2009-2010 influenza pandemrix vaccination. |
2021-11-15 |
2023-08-13 |
Not clear |
Denise Bijlenga, Bram Urbanus, Nick N J J M van der Sluiszen, Sebastiaan Overeem, Jan G Ramaekers, Annemiek Vermeeren, Gert Jan Lammer. Comparing objective wakefulness and vigilance tests to on-the-road driving performance in narcolepsy and idiopathic hypersomnia. Journal of sleep research. 2021-11-10. PMID:34755413. |
participants were 44 patients (aged 18-75 years) with narcolepsy type 1 (nt1), type 2 (nt2) or ih. |
2021-11-10 |
2023-08-13 |
human |
Rannveig Viste, Benedicte A Lie, Marte K Viken, Terje Rootwelt, Stine Knudsen-Heier, Birgitte R Kornu. Narcolepsy type 1 patients have lower levels of effector memory CD4 Sleep medicine. vol 85. 2021-10-28. PMID:34388506. |
narcolepsy type 1 patients have lower levels of effector memory cd4 evidence suggests a cell-mediated autoimmune pathogenesis for narcolepsy type 1 (nt1), but it is not clear whether the disease is associated with overall changes in t cell subsets. |
2021-10-28 |
2023-08-13 |
Not clear |
Rannveig Viste, Marte K Viken, Benedicte A Lie, Hilde T Juvodden, Sebjørg E H Nordstrand, Per M Thorsby, Terje Rootwelt, Birgitte R Kornum, Stine Knudsen-Heie. High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y11 protein levels in narcolepsy type 1. Sleep. vol 44. issue 8. 2021-10-25. PMID:33710305. |
narcolepsy type 1 (nt1) is associated with hypocretin neuron loss. |
2021-10-25 |
2023-08-13 |
Not clear |
Anelia Dietmann, Elena Wenz, Julia van der Meer, Maya Ringli, Jan D Warncke, Ellen Edwards, Markus H Schmidt, Corrado A Bernasconi, Arto Nirkko, Mathias Strub, Silvia Miano, Mauro Manconi, Jens Acker, Sigrid von Manitius, Christian R Baumann, Philip O Valko, Bahtiyar Yilmaz, Andreas-David Brunner, Athina Tzovara, Zhongxing Zhang, Carlo R Largiadèr, Mehdi Tafti, Daniela Latorre, Federica Sallusto, Ramin Khatami, Claudio L A Bassett. The Swiss Primary Hypersomnolence and Narcolepsy Cohort study (SPHYNCS): Study protocol for a prospective, multicentre cohort observational study. Journal of sleep research. vol 30. issue 5. 2021-10-21. PMID:33813771. |
narcolepsy type 1 (nt1) is a disorder with well-established markers and a suspected autoimmune aetiology. |
2021-10-21 |
2023-08-13 |
Not clear |
Anelia Dietmann, Elena Wenz, Julia van der Meer, Maya Ringli, Jan D Warncke, Ellen Edwards, Markus H Schmidt, Corrado A Bernasconi, Arto Nirkko, Mathias Strub, Silvia Miano, Mauro Manconi, Jens Acker, Sigrid von Manitius, Christian R Baumann, Philip O Valko, Bahtiyar Yilmaz, Andreas-David Brunner, Athina Tzovara, Zhongxing Zhang, Carlo R Largiadèr, Mehdi Tafti, Daniela Latorre, Federica Sallusto, Ramin Khatami, Claudio L A Bassett. The Swiss Primary Hypersomnolence and Narcolepsy Cohort study (SPHYNCS): Study protocol for a prospective, multicentre cohort observational study. Journal of sleep research. vol 30. issue 5. 2021-10-21. PMID:33813771. |
the swiss primary hypersomnolence and narcolepsy cohort study (sphyncs) is a comprehensive multicentre cohort study, which will investigate the clinical picture, pathophysiology and long-term course of nt1 and the nbl. |
2021-10-21 |
2023-08-13 |
Not clear |
Silvia Melzi, Anne-Laure Morel, Céline Scoté-Blachon, Roland Liblau, Yves Dauvilliers, Christelle Peyro. Histamine in murine narcolepsy: What do genetic and immune models tell us? Brain pathology (Zurich, Switzerland). 2021-10-21. PMID:34672414. |
an increased number of histaminergic neurons, identified by labeling histidine-decarboxylase (hdc) its synthesis enzyme, was unexpectedly found in patients with narcolepsy type 1 (nt1). |
2021-10-21 |
2023-08-13 |
mouse |
Attila Szakács, Jovanna Dahlgren, Jannie Eklund, A Stefan Aronson, Tove Hallböök, Niklas Dari. Endocrine and metabolic aspects of narcolepsy type 1 in children. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 33. 2021-10-12. PMID:34098245. |
to study whether the onset of narcolepsy type 1 (nt1) in children and adolescents affects bmi, specific metabolic risk factors, the onset of puberty, longitudinal growth or other endocrine functions. |
2021-10-12 |
2023-08-13 |
Not clear |
Alexandre Lecomte, Lucie Barateau, Pedro Pereira, Lars Paulin, Petri Auvinen, Filip Scheperjans, Yves Dauvillier. Gut microbiota composition is associated with narcolepsy type 1. Neurology(R) neuroimmunology & neuroinflammation. vol 7. issue 6. 2021-10-04. PMID:33037102. |
to test the hypothesis that narcolepsy type 1 (nt1) is related to the gut microbiota, we compared the microbiota bacterial communities of patients with nt1 and control subjects. |
2021-10-04 |
2023-08-13 |
human |
Daniela Ballotta, Francesca Talami, Fabio Pizza, Anna Elisabetta Vaudano, Francesca Benuzzi, Giuseppe Plazzi, Stefano Melett. Hypothalamus and amygdala functional connectivity at rest in narcolepsy type 1. NeuroImage. Clinical. vol 31. 2021-09-13. PMID:34252875. |
the aim of the present study was to explore the hemodynamic behaviour of spontaneous bold fluctuation at rest in patients with narcolepsy type 1 (nt1) close to disease onset. |
2021-09-13 |
2023-08-13 |
Not clear |
Pablo Medrano-Martinez, Rosa Peraita-Adrado. Neuropsychological Alterations in Narcolepsy with Cataplexy and the Expression of Cognitive Deficits. Journal of the International Neuropsychological Society : JINS. vol 26. issue 6. 2021-09-09. PMID:31826783. |
the objective of our study was to assess attention processes and executive function in patients with narcolepsy with cataplexy (nt1). |
2021-09-09 |
2023-08-13 |
Not clear |
Anita D'Anselmo, Sergio Agnoli, Marco Filardi, Fabio Pizza, Serena Mastria, Giovanni Emanuele Corazza, Giuseppe Plazz. Being creative during lockdown: The relationship between creative potential and COVID-19-related psychological distress in narcolepsy type 1. Journal of sleep research. 2021-09-08. PMID:34409666. |
considering the positive association between narcoleptic symptoms and creativity, we aimed at exploring the psychological distress associated with covid-19 restrictions and its relationship with depressive symptoms and creativity in patients with narcolepsy type 1 (nt1). |
2021-09-08 |
2023-08-13 |
human |
Anita D'Anselmo, Sergio Agnoli, Marco Filardi, Fabio Pizza, Serena Mastria, Giovanni Emanuele Corazza, Giuseppe Plazz. Being creative during lockdown: The relationship between creative potential and COVID-19-related psychological distress in narcolepsy type 1. Journal of sleep research. 2021-09-08. PMID:34409666. |
a total of 52 patients with nt1 and 50 healthy controls, who completed a previous study on creativity, were contacted during the first lockdown period to complete an online survey evaluating psychological distress related to the covid-19 outbreak, sleep quality, narcolepsy and depressive symptoms, and creative abilities. |
2021-09-08 |
2023-08-13 |
human |
Marieke Vringer, Birgitte Rahbek Kornu. Emerging therapeutic targets for narcolepsy. Expert opinion on therapeutic targets. 2021-08-25. PMID:34402358. |
narcolepsy type 1 (nt1) and type 2 (nt2) are chronic sleep disorders primarily characterized by excessive daytime sleepiness (eds), disturbed sleep-wake regulation, and reduced quality of life. |
2021-08-25 |
2023-08-13 |
Not clear |
Lucie Barateau, Michel Lecendreux, Sofiene Chenini, Anna Laura Rassu, Régis Lopez, Carole Pesenti, Isabelle Jaussent, Séverine Béziat, Yves Dauvillier. Measurement of Narcolepsy Symptoms in School-Aged Children and Adolescents: The Pediatric Narcolepsy Severity Scale. Neurology. vol 97. issue 5. 2021-08-12. PMID:34031200. |
we validated the narcolepsy severity scale (nss) in adults with narcolepsy type 1 (nt1) to quantify the severity, frequency, and consequences of the 5 key narcolepsy symptoms over the last month, and we now developed the pediatric nss (nss-p); thus, the aims of this study were to assess nss-p psychometric properties, validity, and reliability, and to evaluate its responsiveness to treatment in a well-characterized sample of children and adolescents with nt1. |
2021-08-12 |
2023-08-13 |
Not clear |
Althea Lividini, Fabio Pizza, Marco Filardi, Stefano Vandi, Francesca Ingravallo, Elena Antelmi, Oliviero Bruni, Filomena Irene Ilaria Cosentino, Raffaele Ferri, Biancamaria Guarnieri, Sara Marelli, Luigi Ferini-Strambi, Andrea Romigi, Enrica Bonanni, Michelangelo Maestri, Michele Terzaghi, Raffaele Manni, Giuseppe Plazz. Narcolepsy type 1 features across the life span: age impact on clinical and polysomnographic phenotype. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 17. issue 7. 2021-08-05. PMID:33666167. |
narcolepsy type 1 (nt1) is a chronic neurological disorder typically arising during adolescence and young adulthood. |
2021-08-05 |
2023-08-13 |
Not clear |
Virginia Ponziani, Fabio Pizza, Corrado Zenesini, Luca Vignatelli, Andrea Pession, Giuseppe Plazz. BMI changes in pediatric type 1 narcolepsy under sodium oxybate treatment. Sleep. vol 44. issue 7. 2021-08-04. PMID:33388769. |
pediatric type 1 narcolepsy (nt1) is often associated with overweight and obesity. |
2021-08-04 |
2023-08-13 |
Not clear |
Lucie Barateau, Isabelle Jaussent, Julien Roeser, Claudio Ciardiello, Thomas S Kilduff, Yves Dauvillier. Cerebrospinal fluid monoamine levels in central disorders of hypersomnolence. Sleep. vol 44. issue 7. 2021-08-04. PMID:33476396. |
whether the cause of daytime sleepiness in narcolepsy type 1 (nt1) is a direct consequence of the loss of orexin (orx) neurons or whether low orexin reduces the efficacy of the monoaminergic systems to promote wakefulness is unclear. |
2021-08-04 |
2023-08-13 |
Not clear |
Kiran P Maski, Alicia Colclasure, Elaina Little, Erin Steinhart, Thomas E Scammell, William Navidi, Cecilia Diniz Beh. Stability of nocturnal wake and sleep stages defines central nervous system disorders of hypersomnolence. Sleep. vol 44. issue 7. 2021-08-04. PMID:33512510. |
we determine if young people with narcolepsy type 1 (nt1), narcolepsy type 2 (nt2), and idiopathic hypersomnia (ih) have distinct nocturnal sleep stability phenotypes compared to subjectively sleepy controls. |
2021-08-04 |
2023-08-13 |
Not clear |
Sara Alvente, Chiara Berteotti, Stefano Bastianini, Viviana Lo Martire, Gabriele Matteoli, Alessandro Silvani, Giovanna Zoccol. Autonomic mechanisms of blood pressure alterations during sleep in orexin/hypocretin-deficient narcoleptic mice. Sleep. vol 44. issue 7. 2021-08-04. PMID:33517440. |
increase in arterial pressure (ap) during sleep and smaller differences in ap between sleep and wakefulness have been reported in orexin (hypocretin)-deficient mouse models of narcolepsy type 1 (nt1) and confirmed in nt1 patients. |
2021-08-04 |
2023-08-13 |
mouse |