| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matteo Cesari, Kristin Egger, Ambra Stefani, Melanie Bergmann, Abubaker Ibrahim, Elisabeth Brandauer, Birgit Högl, Anna Heidbrede. Differentiation of central disorders of hypersomnolence with manual and artificial-intelligence-derived polysomnographic measures. Sleep. 2022-12-01. PMID:36455881. |
we included video-polysomnography data of 40 narcolepsy type 1 (nt1), 26 narcolepsy type 2 (nt2), 23 idiopathic hypersomnia (ih) patients and 54 subjects with subjective excessive daytime sleepiness (seds). |
2022-12-01 |
2023-08-14 |
human |
| Eva Wiberg Torstensen, Niels Christian Haubjerg Østerby, Fabio Pizza, Giuseppe Plazzi, Elena Antelmi, Monica Moresco, Emmanuel Mignot, Niklas Rye Jørgensen, Gitte Lund Christensen, Benedikte Wanscher, Birgitte Rahbek Kornum, Poul Jørgen Jennu. Repeated measures of hypocretin-1 in Danish and Italian patients with narcolepsy and in controls. Sleep medicine. vol 101. 2022-11-25. PMID:36427467. |
we aimed to revalidate csf-hcrt-1 cut-offs for narcolepsy type 1 (nt1) diagnosis and to evaluate temporal changes in csf-hcrt-1 levels in patients suspected of having central hypersomnia. |
2022-11-25 |
2023-08-14 |
Not clear |
| Hamza O Dhafar, Ahmed S BaHamma. Body Weight and Metabolic Rate Changes in Narcolepsy: Current Knowledge and Future Directions. Metabolites. vol 12. issue 11. 2022-11-24. PMID:36422261. |
patients with narcolepsy, especially nt1, have been found to have a high prevalence of obesity and other metabolic derangements. |
2022-11-24 |
2023-08-14 |
Not clear |
| João H C Campos, Ana C R Aguilar, Fernando Antoneli, Giselle Truzzi, Marcelo R S Briones, Renata C Ferreira, Fernando M S Coelh. Whole-genome analysis of monozygotic Brazilian twins discordant for type 1 narcolepsy: a case report. BMC neurology. vol 22. issue 1. 2022-11-19. PMID:36401198. |
narcolepsy type 1 (nt1) is a rare and chronic neurological disease characterized by sudden sleep attacks, overwhelming daytime drowsiness, and cataplexy. |
2022-11-19 |
2023-08-14 |
Not clear |
| Sona Nevsimalova, Jelena Skibova, Karolina Galuskova, Iva Prihodova, Simona Dostalova, Eszter Maurovich-Horvat, Karel Šonk. Central Disorders of Hypersomnolence: Association with Fatigue, Depression and Sleep Inertia Prevailing in Women. Brain sciences. vol 12. issue 11. 2022-11-11. PMID:36358417. |
one hundred and forty-eight subjects (female 63%) were divided into narcolepsy type 1 (nt1; n = 87, female = 61%), narcolepsy type 2 (nt2; n = 22, female = 59%), and idiopathic hypersomnia (ih; n = 39, female = 69%). |
2022-11-11 |
2023-08-14 |
human |
| Giorgia Varallo, Alessandro Musetti, Anita D'Anselmo, Alessio Gori, Emanuele Maria Giusti, Fabio Pizza, Gianluca Castelnuovo, Giuseppe Plazzi, Christian Franceschin. Exploring Addictive Online Behaviors in Patients with Narcolepsy Type 1. Healthcare (Basel, Switzerland). vol 10. issue 11. 2022-11-11. PMID:36360510. |
narcolepsy type 1 (nt1) is a rare neurological sleep disorder caused by the loss of neurons that produce hypocretin-a peptide that plays a crucial role in addictive behaviors. |
2022-11-11 |
2023-08-14 |
Not clear |
| Sofia M Buonocore, Robbert G van der Mos. Narcolepsy and H1N1 influenza immunology a decade later: What have we learned? Frontiers in immunology. vol 13. 2022-10-31. PMID:36311717. |
narcolepsy with cataplexy (defined as type-1 narcolepsy, nt1) is characterized by an irreversible and chronic deficiency of hypocretin peptides in the hypothalamus. |
2022-10-31 |
2023-08-14 |
Not clear |
| Francisco J Martinez-Orozco, Miguel Fernandez-Arquero, Jose L Vicario, Laura Lillo-Triguero, Elena Ameyugo, Rosa Peraita-Adrado. Long-Term Outcome of a Series of Patients With Narcolepsy Type 1 and Comorbidity With Immunopathological and Autoimmune Diseases. Journal of clinical medicine research. vol 14. issue 8. 2022-09-21. PMID:36128006. |
the aim of this study was to evaluate the long-term outcome of our series of narcolepsy type 1 (nt1) patients with comorbid autoimmune diseases (ads) and other immunopathological diseases (ids), focusing on the incidence of new ads and ids in this sample. |
2022-09-21 |
2023-08-14 |
Not clear |
| Takashi Ishikawa, Hiroe Hara, Ayumi Kawano, Haruhide Kimur. Danavorexton, a selective orexin 2 receptor agonist, provides a symptomatic improvement in a narcolepsy mouse model. Pharmacology, biochemistry, and behavior. 2022-09-15. PMID:36108771. |
narcolepsy type 1 (nt1), caused by loss of orexin neurons, is a neurological disorder characterized by excessive daytime sleepiness, cataplexy, disrupted nighttime sleep, hypnagogic/hypnopompic hallucinations and sleep paralysis, as well as a high risk of obesity. |
2022-09-15 |
2023-08-14 |
mouse |
| Silvia Melzi, Vincent Prevot, Christelle Peyro. Precocious puberty in narcolepsy type 1: Orexin loss and/or neuroinflammation, which is to blame? Sleep medicine reviews. 2022-09-12. PMID:36096986. |
narcolepsy type 1 (nt1) is a rare neurological sleep disorder triggered by postnatal loss of the orexin/hypocretin neuropeptides. |
2022-09-12 |
2023-08-14 |
Not clear |
| Rebecca Evans, Haruhide Kimura, Robert Alexander, Ceri H Davies, Hélène Faessel, Deborah S Hartman, Takashi Ishikawa, Emiliangelo Ratti, Kohei Shimizu, Motohisa Suzuki, Shinichiro Tanaka, Hiroshi Yukitake, Yves Dauvilliers, Emmanuel Migno. Orexin 2 receptor-selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 35. 2022-08-22. PMID:35994639. |
narcolepsy type 1 (nt1) is a sleep disorder caused by a loss of orexinergic neurons. |
2022-08-22 |
2023-08-14 |
mouse |
| Guo Luo, Jing Zhang, Ling Lin, Emmanuel Jean-Marie Migno. Characterization of T cell receptors reactive to HCRT Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 32. 2022-08-01. PMID:35914171. |
characterization of t cell receptors reactive to hcrt narcolepsy type 1 (nt1), a disorder caused by hypocretin/orexin (hcrt) cell loss, is associated with human leukocyte antigen (hla)-dq0602 (98%) and t cell receptor (tcr) polymorphisms. |
2022-08-01 |
2023-08-14 |
human |
| Makoto Honda, Yosuke Shigematsu, Mihoko Shimada, Yoshiko Honda, Katsushi Tokunaga, Taku Miyagaw. Low carnitine palmitoyltransferase1 activity is a risk factor for narcolepsy type 1 and other hypersomnia. Sleep. 2022-07-10. PMID:35810398. |
narcolepsy type 1 (nt1) is associated with metabolic abnormalities but their etiology remains largely unknown. |
2022-07-10 |
2023-08-14 |
Not clear |
| Shan Qu, Peipei Wang, Mengmeng Wang, Chenyang Li, Xiaosong Dong, Liyue Xu, Fang Ha. A comparison of mood, quality of life and executive function among narcolepsy type 1 patients with or without ADHD symptoms in China. Sleep medicine. vol 97. 2022-06-19. PMID:35717731. |
to investigate the prevalence of core attention-deficit/hyperactivity disorder (adhd) symptoms in chinese narcolepsy type 1 (nt1) patients and to explore mood, quality of life, and executive function in narcolepsy patients with or without adhd and the response to methylphenidate hydrochloride extended-release tablets (er-mph) treatment. |
2022-06-19 |
2023-08-14 |
Not clear |
| Zhongxing Zhang, Yves Dauvilliers, Giuseppe Plazzi, Geert Mayer, Gert Jan Lammers, Joan Santamaria, Markku Partinen, Sebastiaan Overeem, Rafael Del Rio Villegas, Karel Sonka, Rosa Peraita-Adrados, Raphaël Heinzer, Aleksandra Wierzbicka, Birgit Högl, Mauro Manconi, Eva Feketeova, Antonio Martins da Silva, Jitka Bušková, Claudio L A Bassetti, Lucie Barateau, Fabio Pizza, Elena Antelmi, Jari K Gool, Rolf Fronczek, Carles Gaig, Ramin Khatam. Idling for Decades: A European Study on Risk Factors Associated with the Delay Before a Narcolepsy Diagnosis. Nature and science of sleep. vol 14. 2022-06-07. PMID:35669411. |
narcolepsy type-1 (nt1) is a rare chronic neurological sleep disorder with excessive daytime sleepiness (eds) as usual first and cataplexy as pathognomonic symptom. |
2022-06-07 |
2023-08-14 |
Not clear |
| Amanda Asp, Frida Lund, Christian Benedict, Pontus Waslin. Impaired procedural memory in narcolepsy type 1. Acta neurologica Scandinavica. 2022-06-02. PMID:35652281. |
here, we investigated whether sleep-dependent memory consolidation differs between healthy subjects and narcolepsy type 1 (nt1) patients. |
2022-06-02 |
2023-08-14 |
human |
| Kunihiro Futenma, Yoshikazu Takaesu, Masaki Nakamura, Kenichi Hayashida, Noboru Takeuchi, Yuichi Inou. Metabolic-Syndrome-Related Comorbidities in Narcolepsy Spectrum Disorders: A Preliminary Cross-Sectional Study in Japan. International journal of environmental research and public health. vol 19. issue 10. 2022-05-28. PMID:35627822. |
narcolepsy types 1 (nt1) and 2 (nt2) and idiopathic hypersomnia (ih) are thought to be a disease continuum known as narcolepsy spectrum disorders (nsds). |
2022-05-28 |
2023-08-13 |
Not clear |
| Adrienne Elisabeth van der Hoeven, Rolf Fronczek, Mink Sebastian Schinkelshoek, Frederik Willem Cornelis Roelandse, Jaap Adriaan Bakker, Sebastiaan Overeem, Denise Bijlenga, Gert Jan Lammer. Intermediate hypocretin-1 cerebrospinal fluid levels and typical cataplexy: their significance in the diagnosis of narcolepsy type 1. Sleep. vol 45. issue 5. 2022-05-13. PMID:35554594. |
the diagnosis of narcolepsy type 1 (nt1) is based upon the presence of cataplexy and/or a cerebrospinal fluid (csf) hypocretin-1/orexin-a level ≤ 110 pg/ml. |
2022-05-13 |
2023-08-13 |
Not clear |
| Adrienne Elisabeth van der Hoeven, Kevin van Waaij, Denise Bijlenga, Frederik Willem Cornelis Roelandse, Sebastiaan Overeem, Jaap Adriaan Bakker, Rolf Fronczek, Gert Jan Lammer. Hypocretin-1 measurements in cerebrospinal fluid using radioimmunoassay: within and between assay reliability and limit of quantification. Sleep. 2022-05-05. PMID:35512685. |
the most sensitive and specific investigative method for the diagnosis of narcolepsy type 1 (nt1) is the determination of hypocretin-1 (orexin a) deficiency (≤110 pg/ml) in cerebrospinal fluid using a radioimmunoassay (ria). |
2022-05-05 |
2023-08-13 |
Not clear |
| Utku Ogan Akyildiz, F Irsel Tezer, Guray Koc, Sevda Ismailogullari, Aylin Bican Demir, Aysin Kisabay Ak, Gulin Sunter, Kezban Aslan Kara, Deniz Tuncel Berktas, Aysenur Sahin, Filiz Azman, Bulent Devrim Akcay, Duygu Kurt Gok, Hikmet Yilmaz, Kadriye Agan, Yavuz Bekmezci, Sinan Yetkin, Murat Aksu, Derya Karadeniz, Gulcin Benbir Sene. The REM-sleep-related characteristics of narcolepsy: a nation-wide multicenter study in Turkey, the REMCON study. Sleep medicine. vol 94. 2022-04-21. PMID:35447401. |
narcolepsy type 1 (nt1) is caused by hypocretin deficiency, the pathophysiology of narcolepsy type 2 (nt2) has not been delineated. |
2022-04-21 |
2023-08-13 |
Not clear |