Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Giorgia Varallo, Christian Franceschini, Giada Rapelli, Corrado Zenesini, Valentina Baldini, Flavia Baccari, Elena Antelmi, Fabio Pizza, Luca Vignatelli, Francesco Biscarini, Francesca Ingravallo, Giuseppe Plazz. Navigating narcolepsy: exploring coping strategies and their association with quality of life in patients with narcolepsy type 1. Scientific reports. vol 14. issue 1. 2024-05-24. PMID:38783152. |
narcolepsy type 1 (nt1) is a chronic neurological disorder characterized by symptoms such as excessive daytime sleepiness, sudden sleep episodes, disrupted nocturnal sleep, cataplexy, sleep paralysis, and hypnagogic hallucinations, which significantly impact the overall well-being and quality of life of individuals. |
2024-05-24 |
2024-05-27 |
human |
Mengmeng Wang, Chaoran Shen, Xinran Liu, Zhaoyan Feng, Huanhuan Wang, Fang Han, Fulong Xia. Executive function performance in children and adolescent patients with narcolepsy type 1. Sleep medicine. vol 119. 2024-05-16. PMID:38754344. |
the executive function profile in patients with narcolepsy type 1 (nt1) has been mentioned; however, limited research exists on children and adolescent patients with nt1.this study aims to assess executive function in children and adolescent patients with nt1 in china, examine potential influencing factors and evaluate the short-term treatment effect on executive function. |
2024-05-16 |
2024-05-27 |
Not clear |
Joseph Yaria, Tobi Olusaki. Challenges in the Management of Narcolepsy in a Resource Limited Setting: A Case Report. Cureus. vol 16. issue 4. 2024-05-13. PMID:38738054. |
we present a case of a 17-year-old male teenager with narcolepsy type 1 (nt1) who had been previously managed as a case of juvenile absence epilepsy in various centers prior to presentation at our facility. |
2024-05-13 |
2024-05-27 |
Not clear |
Vinay Mandagere, Dane Raymen. Atypical isolated cataplexy: two case reports and a mini-review. Neurocase. 2024-04-27. PMID:38678310. |
cataplexy is one of the essential diagnostic features of narcolepsy type 1 (nt1). |
2024-04-27 |
2024-04-30 |
Not clear |
Lucie Barateau, Anis Krache, Alexandre Da Costa, Michel Lecendreux, Rachel Debs, Sofiene Chenini, Nicolas Arlicot, Patrick Vourc'h, Elisa Evangelista, Mathieu Alonso, Anne-Sophie Salabert, Stein Silva, Séverine Béziat, Isabelle Jaussent, Denis Mariano-Goulart, Pierre Payoux, Yves Dauvillier. Microglia Density and Its Association With Disease Duration, Severity, and Orexin Levels in Patients With Narcolepsy Type 1. Neurology. vol 102. issue 10. 2024-04-26. PMID:38669634. |
narcolepsy type 1 (nt1) is due to the loss of hypothalamic neurons that produce orexin (orx), by a suspected immune-mediated process. |
2024-04-26 |
2024-04-29 |
Not clear |
Yanan Gao, Yanting Liu, Sihui Zhao, Yishu Liu, Chen Zhang, Steve Hui, Mark Mikkelsen, Richard A E Edden, Xiao Meng, Bing Yu, Li Xia. MRS study on the correlation between frontal GABA+/Glx ratio and abnormal cognitive function in medication-naive patients with narcolepsy. Sleep medicine. vol 119. 2024-04-16. PMID:38626481. |
to compare the gaba+/glx (glutamate-glutamine) ratio in the prefrontal lobe under non-rapid eye movement sleep between patients with narcolepsy type 1 (nt1) and normal controls and explore the correlation between this difference and abnormal cognitive function, using synchronous electroencephalography-functional magnetic resonance spectroscopy (eeg-fmrs). |
2024-04-16 |
2024-04-19 |
Not clear |
Oriella Gnarra, Julia van der Meer, Jan D Warncke, Livia G Fregolente, Elena Wenz, Kseniia Zub, Uchendu Nwachukwu, Zhongxing Zhang, Ramin Khatami, Sigrid von Manitius, Silvia Miano, Jens Acker, Mathias Strub, Robert Riener, Claudio L A Bassetti, Markus H Schmid. SPHYNCS: Feasibility of long-term monitoring with Fitbit smartwatches in central disorders of hypersomnolence and extraction of digital biomarkers in narcolepsy. Sleep. 2024-03-29. PMID:38551123. |
whereas narcolepsy type 1 (nt1) is well characterized, other cdh disorders lack precise biomarkers. |
2024-03-29 |
2024-03-31 |
human |
Takashi Maruo, Shunsuke Takagi, Sunao Uchida, Hidehiko Takahashi, Genichi Sugihar. Temporal patterns of sleep latency in central hypersomnia and attention deficit hyperactivity disorder: a cluster analysis exploration using Multiple Sleep Latency Test. Frontiers in psychiatry. vol 15. 2024-03-28. PMID:38544845. |
the primary causes of eds are central hypersomnia, including narcolepsy type 1 (nt1), type 2 (nt2), and idiopathic hypersomnia (ih). |
2024-03-28 |
2024-03-30 |
Not clear |
Chiara Del Bianco, Martina Ulivi, Claudio Liguori, Antonio Pisani, Nicola Biagio Mercuri, Fabio Placidi, Francesca Izz. Alexithymia, impulsiveness, emotion, and eating dyscontrol: similarities and differences between narcolepsy type 1 and type 2. Sleep and biological rhythms. vol 21. issue 1. 2024-03-12. PMID:38468909. |
the purposes of this study are to evaluate mood, impulsiveness, emotion, alexithymia, and eating behavior in patients with narcolepsy type 1 (nt1) and narcolepsy type 2 (nt2) compared to healthy controls and to investigate possible correlations between clinical-demographic data, polysomnographic parameters, and subjective questionnaires. |
2024-03-12 |
2024-03-14 |
human |
Lisa Brunel, Enzo Brossaud, Julien Lioret, Antoine Jaffiol, Louison Vanderghote, Léa Cuisinier, Laure Peter-Derex, François Ricordeau, Marine Thieux, Marion Comajuan, Sabine Plancoulaine, Aurore Guyon, Patricia Franc. Effectiveness of an intervention program on physical activity in children with narcolepsy type 1. Sleep medicine. vol 116. 2024-03-09. PMID:38460419. |
physical activity (pa) is recommended as part of the management of narcolepsy type 1 (nt1). |
2024-03-09 |
2024-03-12 |
Not clear |
Thi-Tuyet Trinh Tran, Thi-Hong Nhung Nguyen, Yves Dauvilliers, Roland Liblau, Xuan-Hung Nguye. Absence of specific autoantibodies in patients with narcolepsy type 1 as indicated by an unbiased random peptide-displayed phage screening. PloS one. vol 19. issue 3. 2024-03-05. PMID:38442093. |
narcolepsy type 1 (nt1) is an enigmatic sleep disorder characterized by the selective loss of neurons producing orexin (also named hypocretin) in the lateral hypothalamus. |
2024-03-05 |
2024-03-08 |
Not clear |
Jari K Gool, Zhongxing Zhang, Rolf Fronczek, Pauline Amesz, Ramin Khatami, Gert Jan Lammer. Potential immunological triggers for narcolepsy and idiopathic hypersomnia: Real-world insights on infections and influenza vaccinations. Sleep medicine. vol 116. 2024-03-05. PMID:38442518. |
it is hypothesized that narcolepsy type 1 (nt1) develops in genetically susceptible people who encounter environmental triggers leading to immune-mediated hypocretin-1 deficiency. |
2024-03-05 |
2024-03-08 |
Not clear |
Hilde T Juvodden, Dag Alnæs, Ingrid Agartz, Ole A Andreassen, Andres Server, Per M Thorsby, Lars T Westlye, Stine Knudsen-Heie. Cortical thickness and sub-cortical volumes in post-H1N1 narcolepsy type 1: A brain-wide MRI case-control study. Sleep medicine. vol 116. 2024-03-03. PMID:38432031. |
there was more than a 10-fold increase in the incidence of narcolepsy type 1 (nt1) after the h1n1 mass vaccination in 2009/2010 in several countries. |
2024-03-03 |
2024-03-06 |
Not clear |
Xianhui Zhong, Yuqing Yuan, Qingqing Zhan, Tiantian Yin, Chengxin Ku, Yuxin Liu, Fen Wang, Yongmin Ding, Liying Deng, Wei Wu, Liang Xi. Cell-based versus enzyme-linked immunosorbent assay for detection of anti-Tribbles homolog 2 autoantibodies in Chinese patients with narcolepsy. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2024-02-06. PMID:38318919. |
narcolepsy type 1 (nt1) is attributed to a deficiency in cerebrospinal fluid orexin and is considered linked to autoimmunity. |
2024-02-06 |
2024-02-09 |
mouse |
Marita Hovi, Ulrika Roine, Taina Autti, Hannu Heiskala, Timo Roine, Turkka Kirjavaine. Microstructural White Matter Abnormalities in Children and Adolescents With Narcolepsy Type 1. Pediatric neurology. vol 153. 2024-02-06. PMID:38320459. |
in 2010, the h1n1 pandemrix vaccination campaign was followed by a sudden increase in narcolepsy type 1 (nt1). |
2024-02-06 |
2024-02-09 |
Not clear |
Nicolai Pagh-Berendtsen, Artem Pavlovskyi, Danel Flores Tellez, Christine Egebjerg, Mie Gunni Kolmos, Jessica Justinussen, Birgitte Rahbek Kornu. Downregulation of hypocretin/orexin after H1N1 Pandemrix vaccination of adolescent mice. Sleep. 2024-01-16. PMID:38227834. |
narcolepsy type 1 (nt1), characterized by the loss of hypocretin/orexin (hcrt) production in the lateral hypothalamus, has been linked to pandemrix vaccination during the 2009 h1n1 pandemic especially in children and adolescents. |
2024-01-16 |
2024-01-19 |
mouse |
Lucie Barateau, Sofiene Chenini, Claire Denis, Quentin Lorber, Séverine Béziat, Isabelle Jaussent, Yves Dauvillier. Narcolepsy Severity Scale-2 and Idiopathic Hypersomnia Severity Scale to better quantify symptoms severity and consequences in Narcolepsy type 2. Sleep. 2024-01-10. PMID:38197577. |
narcolepsy type 2 (nt2) is an understudied central disorder of hypersomnolence sharing some similarities with narcolepsy type 1 (nt1) and idiopathic hypersomnia (ih). |
2024-01-10 |
2024-01-13 |
Not clear |
Dandan Sheng, Peihong Li, Zheng Xiao, Xinru Li, Jing Liu, Bo Xiao, Weiping Liu, Luo Zho. Identification of bidirectional causal links between gut microbiota and narcolepsy type 1 using Mendelian randomization. Sleep. 2024-01-04. PMID:38174762. |
narcolepsy type 1 (nt1), characterized by cataplexy and orexin deficiency, is a rare and frequently debilitating neurological disorder. |
2024-01-04 |
2024-01-06 |
Not clear |
Fabio Pizza, Luca Vignatelli, Stefano Vandi, Corrado Zenesini, Francesco Biscarini, Christian Franceschini, Elena Antelmi, Francesca Ingravallo, Emmanuel Mignot, Oliviero Bruni, Lino Nobili, Pierangelo Veggiotti, Raffaele Ferri, Giuseppe Plazz. Role of Daytime Continuous Polysomnography in the Diagnosis of Pediatric Narcolepsy Type 1. Neurology. vol 102. issue 1. 2024-01-02. PMID:38165365. |
narcolepsy type 1 (nt1) is still largely underdiagnosed or diagnosed too late in children. |
2024-01-02 |
2024-01-05 |
Not clear |
Parya Valizadeh, Sara Momtazmanesh, Giuseppe Plazzi, Nima Rezae. Connecting the dots: An updated review of the role of autoimmunity in narcolepsy and emerging immunotherapeutic approaches. Sleep medicine. vol 113. 2023-12-21. PMID:38128432. |
narcolepsy type 1 (nt1) is a chronic disorder characterized by pathological daytime sleepiness and cataplexy due to the disappearance of orexin immunoreactive neurons in the hypothalamus. |
2023-12-21 |
2023-12-24 |
Not clear |