| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Brian T Harel, James J Gattuso, Robert D Latzman, Paul Maruff, Thomas E Scammell, Giuseppe Plazz. The nature and magnitude of cognitive impairment in narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia: a meta-analysis. Sleep advances : a journal of the Sleep Research Society. vol 5. issue 1. 2024-07-22. PMID:39036743. |
people with narcolepsy type 1 (nt1), narcolepsy type 2 (nt2), and idiopathic hypersomnia (ih) often report cognitive impairment which can be quite burdensome but is rarely evaluated in routine clinical practice. |
2024-07-22 |
2024-07-24 |
Not clear |
| Stefano Bastianini, Sara Alvente, Chiara Berteotti, Viviana Lo Martire, Gabriele Matteoli, Elena Miglioranza, Alessandro Silvani, Giovanna Zoccol. Ageing-related modification of sleep and breathing in orexin-knockout narcoleptic mice. Journal of sleep research. 2024-07-20. PMID:39032099. |
narcolepsy type-1 (nt1) is a lifelong sleep disease, characterised by impairment of the orexinergic system, with a typical onset during adolescence and young adulthood. |
2024-07-20 |
2024-07-24 |
mouse |
| Wei-Chih Chin, Yu-Shu Huang, I Tang, Chih-Huan Wan. Long-term follow-up of symptom and quality of life changes in patients with narcolepsy during and after the COVID-19 pandemic. Sleep and biological rhythms. vol 22. issue 3. 2024-07-04. PMID:38962790. |
patients with type 1 or type 2 narcolepsy (nt1, nt2) were retrospectively recruited and prospectively followed from 2020 to 2023. |
2024-07-04 |
2024-07-10 |
Not clear |
| Brian Tracey, Mark Culp, Stephan Fabregas, Emmanuel Mignot, Derek L Buhl, Dmitri Volfso. Novel biomarkers derived from the Maintenance of Wakefulness Test as predictors of sleepiness and response to treatment. Sleep. 2024-07-02. PMID:38954525. |
here, we explored microsleeps, sleep probability measures derived from automated sleep scoring, and quantitative electroencephalography (qeeg) features as additional mwt biomarkers of daytime sleepiness, using data from a phase 1b trial of the selective orexin receptor 2 agonist danavorexton (tak-925) in people with narcolepsy type 1 (nt1) or type 2 (nt2). |
2024-07-02 |
2024-07-06 |
Not clear |
| Brian Tracey, Mark Culp, Stephan Fabregas, Emmanuel Mignot, Derek L Buhl, Dmitri Volfso. Novel biomarkers derived from the Maintenance of Wakefulness Test as predictors of sleepiness and response to treatment. Sleep. 2024-07-02. PMID:38954525. |
the slopes of line-fits to both the log-transformed sleepiness score or log-transformed θ/α ratio correlated well to (inverse) mwt sol for nt1 (r = 0.93 and r = 0.83, respectively) and nt2 (r = 0.97 and r = 0.84, respectively), suggesting that individuals with narcolepsy have increased sleepiness immediately after lights-off. |
2024-07-02 |
2024-07-06 |
Not clear |
| Niels Christian Haubjerg Østerby, Niklas Rye Jørgensen, Poul Jørgen Jennu. Evaluating routine blood and cerebrospinal fluid samples in narcolepsy patients. Scandinavian journal of clinical and laboratory investigation. 2024-06-27. PMID:38934461. |
cerebrospinal fluid hypocretin-1 is proven to be a precise diagnostic marker of narcolepsy type 1 (nt1). |
2024-06-27 |
2024-06-29 |
Not clear |
| Samia Hamdan, Pontus Wasling, Alexander Lin. High-resolution HLA sequencing and hypocretin receptor 2 autoantibodies in narcolepsy type 1 and type 2. International journal of immunogenetics. 2024-06-20. PMID:38898624. |
narcolepsy is classified into type 1 (nt1) and type 2 (nt2). |
2024-06-20 |
2024-06-22 |
human |
| Yuanhang Pan, Xinbo Zhang, Xinyu Wen, Na Yuan, Li Guo, Yifan Shi, Yuanyuan Jia, Yanzhao Guo, Fengli Hao, Shuyi Qu, Ze Chen, Lei Yang, Xiaoli Wang, Yonghong Li. Development and validation of a machine learning model for prediction of comorbid major depression disorder among narcolepsy type 1. Sleep medicine. vol 119. 2024-06-16. PMID:38810481. |
major depression disorder (mdd) forms a common psychiatric comorbidity among patients with narcolepsy type 1 (nt1), yet its impact on patients with nt1 is often overlooked by neurologists. |
2024-06-16 |
2024-06-19 |
Not clear |
| Jieyang Yu, Yanan Zhang, Lijia Cai, Qingqing Sun, Wanru Li, Junfang Zhou, Jianmin Liang, Zan Wan. The Changed Nocturnal Sleep Structure and Higher Anxiety, Depression, and Fatigue in Patients with Narcolepsy Type 1. Nature and science of sleep. vol 16. 2024-06-14. PMID:38873239. |
this study aimed to evaluate nocturnal sleep structure and anxiety, depression, and fatigue in patients with narcolepsy type 1 (nt1). |
2024-06-14 |
2024-06-16 |
Not clear |
| Valerie Martinet, Laura Sinkunaite, Marie Bruynee. An Unusual Cause of Increasing Excessive Daytime Sleepiness in a CPAP-treated Obstructive Sleep Apnea Patient. Sleep science (Sao Paulo, Brazil). vol 17. issue 2. 2024-06-08. PMID:38846592. |
the onset of narcolepsy type 1 (nt1) occurs after 50 years of age in less than 2% of the cases. |
2024-06-08 |
2024-06-10 |
Not clear |
| Yuanhang Pan, Di Zhao, Xinbo Zhang, Na Yuan, Lei Yang, Yuanyuan Jia, Yanzhao Guo, Ze Chen, Zezhi Wang, Shuyi Qu, Junxiang Bao, Yonghong Li. Machine learning-Based model for prediction of Narcolepsy Type 1 in Patients with Obstructive Sleep Apnea with Excessive Daytime Sleepiness. Nature and science of sleep. vol 16. 2024-06-05. PMID:38836216. |
excessive daytime sleepiness (eds) forms a prevalent symptom of obstructive sleep apnea (osa) and narcolepsy type 1 (nt1), while the latter might always be overlooked. |
2024-06-05 |
2024-06-07 |
Not clear |
| Giorgia Varallo, Christian Franceschini, Giada Rapelli, Corrado Zenesini, Valentina Baldini, Flavia Baccari, Elena Antelmi, Fabio Pizza, Luca Vignatelli, Francesco Biscarini, Francesca Ingravallo, Giuseppe Plazz. Navigating narcolepsy: exploring coping strategies and their association with quality of life in patients with narcolepsy type 1. Scientific reports. vol 14. issue 1. 2024-05-24. PMID:38783152. |
narcolepsy type 1 (nt1) is a chronic neurological disorder characterized by symptoms such as excessive daytime sleepiness, sudden sleep episodes, disrupted nocturnal sleep, cataplexy, sleep paralysis, and hypnagogic hallucinations, which significantly impact the overall well-being and quality of life of individuals. |
2024-05-24 |
2024-05-27 |
human |
| Mengmeng Wang, Chaoran Shen, Xinran Liu, Zhaoyan Feng, Huanhuan Wang, Fang Han, Fulong Xia. Executive function performance in children and adolescent patients with narcolepsy type 1. Sleep medicine. vol 119. 2024-05-16. PMID:38754344. |
the executive function profile in patients with narcolepsy type 1 (nt1) has been mentioned; however, limited research exists on children and adolescent patients with nt1.this study aims to assess executive function in children and adolescent patients with nt1 in china, examine potential influencing factors and evaluate the short-term treatment effect on executive function. |
2024-05-16 |
2024-05-27 |
Not clear |
| Joseph Yaria, Tobi Olusaki. Challenges in the Management of Narcolepsy in a Resource Limited Setting: A Case Report. Cureus. vol 16. issue 4. 2024-05-13. PMID:38738054. |
we present a case of a 17-year-old male teenager with narcolepsy type 1 (nt1) who had been previously managed as a case of juvenile absence epilepsy in various centers prior to presentation at our facility. |
2024-05-13 |
2024-05-27 |
Not clear |
| Vinay Mandagere, Dane Raymen. Atypical isolated cataplexy: two case reports and a mini-review. Neurocase. 2024-04-27. PMID:38678310. |
cataplexy is one of the essential diagnostic features of narcolepsy type 1 (nt1). |
2024-04-27 |
2024-04-30 |
Not clear |
| Lucie Barateau, Anis Krache, Alexandre Da Costa, Michel Lecendreux, Rachel Debs, Sofiene Chenini, Nicolas Arlicot, Patrick Vourc'h, Elisa Evangelista, Mathieu Alonso, Anne-Sophie Salabert, Stein Silva, Séverine Béziat, Isabelle Jaussent, Denis Mariano-Goulart, Pierre Payoux, Yves Dauvillier. Microglia Density and Its Association With Disease Duration, Severity, and Orexin Levels in Patients With Narcolepsy Type 1. Neurology. vol 102. issue 10. 2024-04-26. PMID:38669634. |
narcolepsy type 1 (nt1) is due to the loss of hypothalamic neurons that produce orexin (orx), by a suspected immune-mediated process. |
2024-04-26 |
2024-04-29 |
Not clear |
| Yanan Gao, Yanting Liu, Sihui Zhao, Yishu Liu, Chen Zhang, Steve Hui, Mark Mikkelsen, Richard A E Edden, Xiao Meng, Bing Yu, Li Xia. MRS study on the correlation between frontal GABA+/Glx ratio and abnormal cognitive function in medication-naive patients with narcolepsy. Sleep medicine. vol 119. 2024-04-16. PMID:38626481. |
to compare the gaba+/glx (glutamate-glutamine) ratio in the prefrontal lobe under non-rapid eye movement sleep between patients with narcolepsy type 1 (nt1) and normal controls and explore the correlation between this difference and abnormal cognitive function, using synchronous electroencephalography-functional magnetic resonance spectroscopy (eeg-fmrs). |
2024-04-16 |
2024-04-19 |
Not clear |
| Oriella Gnarra, Julia van der Meer, Jan D Warncke, Livia G Fregolente, Elena Wenz, Kseniia Zub, Uchendu Nwachukwu, Zhongxing Zhang, Ramin Khatami, Sigrid von Manitius, Silvia Miano, Jens Acker, Mathias Strub, Robert Riener, Claudio L A Bassetti, Markus H Schmid. SPHYNCS: Feasibility of long-term monitoring with Fitbit smartwatches in central disorders of hypersomnolence and extraction of digital biomarkers in narcolepsy. Sleep. 2024-03-29. PMID:38551123. |
whereas narcolepsy type 1 (nt1) is well characterized, other cdh disorders lack precise biomarkers. |
2024-03-29 |
2024-03-31 |
human |
| Takashi Maruo, Shunsuke Takagi, Sunao Uchida, Hidehiko Takahashi, Genichi Sugihar. Temporal patterns of sleep latency in central hypersomnia and attention deficit hyperactivity disorder: a cluster analysis exploration using Multiple Sleep Latency Test. Frontiers in psychiatry. vol 15. 2024-03-28. PMID:38544845. |
the primary causes of eds are central hypersomnia, including narcolepsy type 1 (nt1), type 2 (nt2), and idiopathic hypersomnia (ih). |
2024-03-28 |
2024-03-30 |
Not clear |
| Chiara Del Bianco, Martina Ulivi, Claudio Liguori, Antonio Pisani, Nicola Biagio Mercuri, Fabio Placidi, Francesca Izz. Alexithymia, impulsiveness, emotion, and eating dyscontrol: similarities and differences between narcolepsy type 1 and type 2. Sleep and biological rhythms. vol 21. issue 1. 2024-03-12. PMID:38468909. |
the purposes of this study are to evaluate mood, impulsiveness, emotion, alexithymia, and eating behavior in patients with narcolepsy type 1 (nt1) and narcolepsy type 2 (nt2) compared to healthy controls and to investigate possible correlations between clinical-demographic data, polysomnographic parameters, and subjective questionnaires. |
2024-03-12 |
2024-03-14 |
human |