| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei-Chih Chin, Yu-Shu Huang, I Tang, Pin-Yi Lee, Chih-Huan Wang, Kuo-Yu Cha. Impact of Taiwan's 2021 COVID-19 lockdown on the symptom severity and quality of life of patients with narcolepsy. Sleep and biological rhythms. 2023-06-26. PMID:37363640. |
patients with type 1 and type 2 narcolepsy (nt1 and nt2, respectively) aged 6-40 years were retrospectively recruited from our narcolepsy cohort study. |
2023-06-26 |
2023-08-14 |
Not clear |
| Yves Dauvilliers, Thomas Roth, Richard Bogan, Michael J Thorpy, Anne Marie Morse, Asim Roy, Jordan Dubow, Jennifer Gudema. Efficacy of Once-Nightly Sodium Oxybate (FT218) in Narcolepsy Type 1 and Type 2: Post Hoc Analysis From the Phase 3 REST-ON Trial. Sleep. 2023-05-29. PMID:37246913. |
post hoc analyses from the phase 3 rest-on trial evaluated efficacy of extended-release once-nightly sodium oxybate (on-sxb; ft218) vs placebo for daytime sleepiness and disrupted nighttime sleep in narcolepsy type 1 (nt1) and 2 (nt2). |
2023-05-29 |
2023-08-14 |
Not clear |
| Samantha Mombelli, François Ricordeau, Léa Gillard, Rosa Lecca, Tiphaine Vidal, Bruno Pereira, Patricia Beudin, Nicolas Vitello, Helene Bastuji, Laure Peter-Derex, Maria Livia Fantin. Psychobehavioural profile in narcolepsy type 1 with and without REM sleep behaviour disorder. Journal of sleep research. 2023-05-24. PMID:37222001. |
rem sleep behaviour disorder (rbd) is common in narcolepsy type 1 (nt1). |
2023-05-24 |
2023-08-14 |
Not clear |
| Louise Piilgaard, Laura Rose, Jessica L Justinussen, Camille Gylling Hviid, René Lemcke, Petrine Wellendorph, Birgitte Rahbek Kornu. Non-invasive detection of narcolepsy type I phenotypical features and disease progression by continuous home-cage monitoring of activity in two mouse models: the HCRT-KO and DTA model. Sleep. 2023-05-20. PMID:37210587. |
narcolepsy type 1 (nt1) is a neurological disorder caused by disruption of hypocretin (hcrt; or orexin) neurotransmission leading to fragmented sleep/wake states, excessive daytime sleepiness (eds), and cataplexy (abrupt muscle atonia during wakefulness). |
2023-05-20 |
2023-08-14 |
mouse |
| Hanna M Ollila, Eilon Sharon, Ling Lin, Nasa Sinnott-Armstrong, Aditya Ambati, Selina M Yogeshwar, Ryan P Hillary, Otto Jolanki, Juliette Faraco, Mali Einen, Guo Luo, Jing Zhang, Fang Han, Han Yan, Xiao Song Dong, Jing Li, Jun Zhang, Seung-Chul Hong, Tae Won Kim, Yves Dauvilliers, Lucie Barateau, Gert Jan Lammers, Rolf Fronczek, Geert Mayer, Joan Santamaria, Isabelle Arnulf, Stine Knudsen-Heier, May Kristin Lyamouri Bredahl, Per Medbøe Thorsby, Giuseppe Plazzi, Fabio Pizza, Monica Moresco, Catherine Crowe, Stephen K Van den Eeden, Michel Lecendreux, Patrice Bourgin, Takashi Kanbayashi, Francisco J Martínez-Orozco, Rosa Peraita-Adrados, Antonio Benetó, Jacques Montplaisir, Alex Desautels, Yu-Shu Huang, Poul Jennum, Sona Nevsimalova, David Kemlink, Alex Iranzo, Sebastiaan Overeem, Aleksandra Wierzbicka, Peter Geisler, Karel Sonka, Makoto Honda, Birgit Högl, Ambra Stefani, Fernando Morgadinho Coelho, Vilma Mantovani, Eva Feketeova, Mia Wadelius, Niclas Eriksson, Hans Smedje, Pär Hallberg, Per Egil Hesla, David Rye, Zerrin Pelin, Luigi Ferini-Strambi, Claudio L Bassetti, Johannes Mathis, Ramin Khatami, Adi Aran, Sheela Nampoothiri, Tomas Olsson, Ingrid Kockum, Markku Partinen, Markus Perola, Birgitte R Kornum, Sina Rueger, Juliane Winkelmann, Taku Miyagawa, Hiromi Toyoda, Seik-Soon Khor, Mihoko Shimada, Katsushi Tokunaga, Manuel Rivas, Jonathan K Pritchard, Neil Risch, Zoltan Kutalik, Ruth O'Hara, Joachim Hallmayer, Chun Jimmie Ye, Emmanuel J Migno. Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy. Nature communications. vol 14. issue 1. 2023-05-15. PMID:37188663. |
narcolepsy type 1 (nt1) is caused by a loss of hypocretin/orexin transmission. |
2023-05-15 |
2023-08-14 |
Not clear |
| Ikram Ayoub, Yves Dauvilliers, Lucie Barateau, Thaïs Vermeulen, Emmanuelle Mouton-Barbosa, Marlène Marcellin, Anne Gonzalez-de-Peredo, Catharina C Gross, Abdelhadi Saoudi, Roland Libla. Cerebrospinal fluid proteomics in recent-onset Narcolepsy type 1 reveals activation of the complement system. Frontiers in immunology. vol 14. 2023-05-01. PMID:37122721. |
narcolepsy type 1 (nt1) is a rare, chronic and disabling neurological disease causing excessive daytime sleepiness and cataplexy. |
2023-05-01 |
2023-08-14 |
Not clear |
| Takashi Ishikawa, Hiroe Hara, Ayumi Kawano, Kimio Tohyama, Yuichi Kajita, Yuhei Miyanohana, Tatsuki Koike, Haruhide Kimur. The Journal of pharmacology and experimental therapeutics. 2023-03-31. PMID:37001988. |
loss of orexin neurons is associated with narcolepsy type 1 (nt1), which is characterized by multiple symptoms including excessive daytime sleepiness and cataplexy. |
2023-03-31 |
2023-08-14 |
mouse |
| Akeem Sanni, Mona Goli, Jingfu Zhao, Junyao Wang, Chloe Barsa, Samer El Hayek, Farid Talih, Bartolo Lanuzza, Firas Kobeissy, Giuseppe Plazzi, Monica Moresco, Stefania Mondello, Raffaele Ferri, Yehia Mechre. LC-MS/MS-Based Proteomics Approach for the Identification of Candidate Serum Biomarkers in Patients with Narcolepsy Type 1. Biomolecules. vol 13. issue 3. 2023-03-29. PMID:36979356. |
narcolepsy type 1 (nt1) is the most common type of narcolepsy known to be caused by the loss of specific neurons responsible for producing peptide neurotransmitters (orexins/hypocretins), resulting in a sleep-wake cycle disorder. |
2023-03-29 |
2023-08-14 |
human |
| Karin Janssens, Pauline Amesz, Yvonne Nuvelstijn, Claire Donjacour, Danielle Hendriks, Els Peeters, Laury Quaedackers, Nele Vandenbussche, Sigrid Pillen, Gert Jan Lammer. School Problems and School Support for Children with Narcolepsy: Parent, Teacher, and Child Reports. International journal of environmental research and public health. vol 20. issue 6. 2023-03-29. PMID:36982084. |
to assess problems faced by children with type 1 narcolepsy (nt1) at school and obtain insight into potential interventions for these problems. |
2023-03-29 |
2023-08-14 |
Not clear |
| A Romigi, M Caccamo, F Testa, D Ticconi, S Cappellano, B Di Gioia, G Vitrani, I Rosenzweig, D Centonz. Muscle atonia index during multiple sleep latency test: A possible marker to differentiate narcolepsy from other hypersomnias. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 149. 2023-03-04. PMID:36870217. |
our study aimed to determine the changes in muscle tone (atonia index, ai) at different levels of vigilance during the entire multiple sleep latency test (mslt) and each nap in people with narcolepsy type 1 (nt1) and 2 (nt2) compared with other hypersomnias and its potential diagnostic value. |
2023-03-04 |
2023-08-14 |
Not clear |
| Maria Paola Mogavero, Lourdes M DelRosso, Oliviero Bruni, Michele Salemi, Maria Salsone, Fabiana Novellino, Marco Zucconi, Luigi Ferini Strambi, Raffaele Ferr. Genetics and epigenetics of rare hypersomnia. Trends in genetics : TIG. 2023-02-26. PMID:36842900. |
herein we focus on connections between genetics and some central disorders of hypersomnolence - narcolepsy types 1 and 2 (nt1, nt2), idiopathic hypersomnia (ih), and kleine-levin syndrome (kls) - for a better understanding of their etiopathogenetic mechanisms and a better diagnostic and therapeutic definition. |
2023-02-26 |
2023-08-14 |
Not clear |
| Alessandra D'Alterio, Marco Menchetti, Corrado Zenesini, Andrea Rossetti, Luca Vignatelli, Christian Franceschini, Giorgia Varallo, Fabio Pizza, Giuseppe Plazzi, Francesca Ingravall. Resilience and its correlates in patients with narcolepsy type 1. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2023-01-23. PMID:36689313. |
this study aimed to explore resilience and its possible association with sociodemographic and clinical features in patients with narcolepsy type 1 (nt1). |
2023-01-23 |
2023-08-14 |
Not clear |
| b' Eva Feketeov\\xc3\\xa1, Jozef Draga\\xc5\\xa1ek, Katar\\xc3\\xadna Klobu\\xc4\\x8dn\\xc3\\xadkov\\xc3\\xa1, Peter \\xc4\\x8eurd\\xc3\\xadk, Simona \\xc4\\x8carnakovi\\xc4\\x8d, Miriam Slavkovsk\\xc3\\xa1, Martina Chylov\\xc3\\xa. Psychotic Episode and Schizophrenia in Slovakian Narcolepsy Database. Brain sciences. vol 13. issue 1. 2023-01-21. PMID:36672025.' |
narcolepsy type 1 (nt1), a central disorder of hypersomnolence, is associated with mood, anxiety or hyperactivity mental disorders. |
2023-01-21 |
2023-08-14 |
Not clear |
| b' Eva Feketeov\\xc3\\xa1, Jozef Draga\\xc5\\xa1ek, Katar\\xc3\\xadna Klobu\\xc4\\x8dn\\xc3\\xadkov\\xc3\\xa1, Peter \\xc4\\x8eurd\\xc3\\xadk, Simona \\xc4\\x8carnakovi\\xc4\\x8d, Miriam Slavkovsk\\xc3\\xa1, Martina Chylov\\xc3\\xa. Psychotic Episode and Schizophrenia in Slovakian Narcolepsy Database. Brain sciences. vol 13. issue 1. 2023-01-21. PMID:36672025.' |
comorbid schizophrenia with nt1 in the slovakian narcolepsy database was within the prevalence expected in the general population. |
2023-01-21 |
2023-08-14 |
Not clear |
| R Peraita-Adrados, J M Bellón, L Lillo-Triguero, P López-Esteban, P Medrano-Martíne. Long-term follow-up on the effects of sodium oxybate on daytime sleepiness and sleep architecture in patients with narcolepsy type 1. Revista de neurologia. vol 76. issue 2. 2023-01-12. PMID:36631962. |
sodium oxybate (sxb) was administered for the first time in 1979 in 16 patients with narcolepsy with cataplexy (nt1) that improved up to 20 months. |
2023-01-12 |
2023-08-14 |
Not clear |
| Zhao Liu, Ruiqian Guan, Limin Pa. TCM syndrome differentiation and treatment of narcolepsy based on neurobiological mechanism: A review. Medicine. vol 101. issue 49. 2023-01-10. PMID:36626491. |
narcolepsy is divided into narcolepsy type 1 (nt1) and narcolepsis type 2 (nt2). |
2023-01-10 |
2023-08-14 |
human |
| Zhao Liu, Ruiqian Guan, Limin Pa. TCM syndrome differentiation and treatment of narcolepsy based on neurobiological mechanism: A review. Medicine. vol 101. issue 49. 2023-01-10. PMID:36626491. |
human leukocyte antigen alleles have been found to strongly influence the development of narcolepsy, with more than 90% of nt1 patients carrying the human leukocyte antigen ii allele dqb1*06:02. |
2023-01-10 |
2023-08-14 |
human |
| Gerard Mayà, Carles Gaig, Alex Iranzo, Joan Santamari. Temporal distribution of sleep onset REM periods and N3 sleep in the MSLT and night polysomnogram of narcolepsy type 1 and other hypersomnias. Sleep medicine. vol 102. 2023-01-02. PMID:36592569. |
we studied the temporal distribution of soremps and associated sleep stages in the mslt of patients with narcolepsy type 1 (nt1) and other hypersomnias (oh). |
2023-01-02 |
2023-08-14 |
Not clear |
| Rannveig Viste, Louise F Follin, Birgitte R Kornum, Benedicte A Lie, Marte K Viken, Per M Thorsby, Terje Rootwelt, Julie A E Christensen, Stine Knudsen-Heie. Increased muscle activity during sleep and more RBD symptoms in H1N1-(Pandemrix)-vaccinated narcolepsy type 1 patients compared with their nonnarcoleptic siblings. Sleep. 2022-12-23. PMID:36562330. |
narcolepsy type 1 (nt1) is characterized by unstable sleep-wake and muscle tonus regulation during sleep. |
2022-12-23 |
2023-08-14 |
Not clear |
| Lanxiang Wu, Qingqing Zhan, Qian Liu, Suheng Xie, Sheng Tian, Liang Xie, Wei W. Abnormal Regional Spontaneous Neural Activity and Functional Connectivity in Unmedicated Patients with Narcolepsy Type 1: A Resting-State fMRI Study. International journal of environmental research and public health. vol 19. issue 23. 2022-12-11. PMID:36497558. |
previous resting-state functional magnetic resonance imaging (fmri) studies have mainly focused on cerebral functional alteration in processing different emotional stimuli in patients with narcolepsy type 1 (nt1), but were short of exploration of characteristic brain activity and its remote interaction patterns. |
2022-12-11 |
2023-08-14 |
Not clear |