| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Dowling, W Husar, J Menonna, H Donnenfeld, S Cook, M Sidh. Cell death and birth in multiple sclerosis brain. Journal of the neurological sciences. vol 149. issue 1. 1997-07-10. PMID:9168159. |
the hallmark of the brain pathology in multiple sclerosis is the white matter plaque, characterized by myelin destruction and oligodendrocyte loss. |
1997-07-10 |
2023-08-12 |
Not clear |
| K Genç, D L Dona, A T Rede. Increased CD80(+) B cells in active multiple sclerosis and reversal by interferon beta-1b therapy. The Journal of clinical investigation. vol 99. issue 11. 1997-07-01. PMID:9169496. |
during multiple sclerosis (ms) exacerbations, circulating immune cells are activated, th1 cytokine levels in the blood are elevated, and blood-derived immune cells destroy brain oligodendroglia. |
1997-07-01 |
2023-08-12 |
Not clear |
| G Giovannoni, S J Heales, N C Silver, J O'Riordan, R F Miller, J M Land, J B Clark, E J Thompso. Raised serum nitrate and nitrite levels in patients with multiple sclerosis. Journal of the neurological sciences. vol 145. issue 1. 1997-06-09. PMID:9073032. |
nitric oxide and its highly reactive derivative peroxynitrite have been implicated as non-specific inflammatory mediators of neuronal and oligodendrocyte damage and death in multiple sclerosis. |
1997-06-09 |
2023-08-12 |
human |
| C C Bernard, T G Johns, A Slavin, M Ichikawa, C Ewing, J Liu, J Bettadapur. Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis. Journal of molecular medicine (Berlin, Germany). vol 75. issue 2. 1997-05-28. PMID:9083925. |
myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis. |
1997-05-28 |
2023-08-12 |
mouse |
| J A Kamhol. Regulation of myelin development. Multiple sclerosis (Houndmills, Basingstoke, England). vol 2. issue 5. 1997-03-25. PMID:9050362. |
these three transcription factors are thus important for the normal process of oligodendrocyte differentiation and myelination, and may be involved in the molecular pathogenesis of both demyelination and remyelination in multiple sclerosis. |
1997-03-25 |
2023-08-12 |
Not clear |
| M Ichikawa, T G Johns, M Adelmann, C C Bernar. Antibody response in Lewis rats injected with myelin oligodendrocyte glycoprotein derived peptides. International immunology. vol 8. issue 11. 1997-03-03. PMID:8943561. |
previous studies from our laboratory have demonstrated a predominant response to myelin oligodendrocyte glycoprotein (mog) in patients with multiple sclerosis (ms) and showed that this molecule is able to induce in lewis rats a chronic relapsing ms-like disease with extensive demyelination. |
1997-03-03 |
2023-08-12 |
rat |
| B G Xiao, G X Zhang, C G Ma, H Lin. The cerebrospinal fluid from patients with multiple sclerosis promotes neuronal and oligodendrocyte damage by delayed production of nitric oxide in vitro. Journal of the neurological sciences. vol 142. issue 1-2. 1997-02-07. PMID:8902730. |
the cerebrospinal fluid from patients with multiple sclerosis promotes neuronal and oligodendrocyte damage by delayed production of nitric oxide in vitro. |
1997-02-07 |
2023-08-12 |
Not clear |
| B G Xiao, G X Zhang, C G Ma, H Lin. The cerebrospinal fluid from patients with multiple sclerosis promotes neuronal and oligodendrocyte damage by delayed production of nitric oxide in vitro. Journal of the neurological sciences. vol 142. issue 1-2. 1997-02-07. PMID:8902730. |
nitric oxide (no) may be involved in myelin and oligodendrocyte injury associated with multiple sclerosis (ms), a demyelinating disease of unknown etiology. |
1997-02-07 |
2023-08-12 |
Not clear |
| M J Crowe, J C Bresnahan, S L Shuman, J N Masters, M S Beatti. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nature medicine. vol 3. issue 1. 1997-01-31. PMID:8986744. |
as cytokines have been shown to mediate oligodendrocyte death in vitro, it seems likely that chronic demyelination after cns injury shares features with chronic degenerative disorders like multiple sclerosis. |
1997-01-31 |
2023-08-12 |
rat |
| S D D'Souza, B Bonetti, V Balasingam, N R Cashman, P A Barker, A B Troutt, C S Raine, J P Ante. Multiple sclerosis: Fas signaling in oligodendrocyte cell death. The Journal of experimental medicine. vol 184. issue 6. 1997-01-30. PMID:8976190. |
multiple sclerosis: fas signaling in oligodendrocyte cell death. |
1997-01-30 |
2023-08-12 |
human |
| S D D'Souza, B Bonetti, V Balasingam, N R Cashman, P A Barker, A B Troutt, C S Raine, J P Ante. Multiple sclerosis: Fas signaling in oligodendrocyte cell death. The Journal of experimental medicine. vol 184. issue 6. 1997-01-30. PMID:8976190. |
in this study, we examined the potential of fas to contribute to oligodendrocyte (ol) injury and demyelination as they occur in the human demyelinating disease multiple sclerosis (ms). |
1997-01-30 |
2023-08-12 |
human |
| C P Genain, K Abel, N Belmar, F Villinger, D P Rosenberg, C Linington, C S Raine, S L Hause. Late complications of immune deviation therapy in a nonhuman primate. Science (New York, N.Y.). vol 274. issue 5295. 1997-01-09. PMID:8953031. |
in a marmoset model of multiple sclerosis induced by myelin oligodendrocyte glycoprotein (mog), marmosets tolerized to mog were protected against acute disease, but after tolerization treatment a lethal demyelinating disorder emerged. |
1997-01-09 |
2023-08-12 |
marmoset |
| C F Brosnan, C S Rain. Mechanisms of immune injury in multiple sclerosis. Brain pathology (Zurich, Switzerland). vol 6. issue 3. 1997-01-06. PMID:8864282. |
in this review, we address current concepts regarding the mechanisms of tissue damage that lead to demyelination and oligodendrocyte loss in multiple sclerosis. |
1997-01-06 |
2023-08-12 |
Not clear |
| N Mendel Kerlero de Rosbo, A Ben-Nu. Delineation of the minimal encephalitogenic epitope within the immunodominant region of myelin oligodendrocyte glycoprotein: diverse V beta gene usage by T cells recognizing the core epitope encephalitogenic for T cell receptor V beta b and T cell receptor V beta a H-2b mice. European journal of immunology. vol 26. issue 10. 1996-12-10. PMID:8898962. |
the nature of the autoimmune t cell response to myelin oligodendrocyte glycoprotein (mog), recently recognized as a potential target antigen in multiple sclerosis (ms), has not yet been characterized, in contrast to the t cell reactivity to other potential target antigens in ms such as myelin basic protein and proteolipid protein. |
1996-12-10 |
2023-08-12 |
mouse |
| A Ben-Nun, I Mendel, R Bakimer, M Fridkis-Hareli, D Teitelbaum, R Arnon, M Sela, N Kerlero de Rosb. The autoimmune reactivity to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis is potentially pathogenic: effect of copolymer 1 on MOG-induced disease. Journal of neurology. vol 243. issue 4 Suppl 1. 1996-12-04. PMID:8965116. |
the autoimmune reactivity to myelin oligodendrocyte glycoprotein (mog) in multiple sclerosis is potentially pathogenic: effect of copolymer 1 on mog-induced disease. |
1996-12-04 |
2023-08-12 |
mouse |
| T Vartanian, Y Li, M Zhao, K Stefansso. Interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis. Molecular medicine (Cambridge, Mass.). vol 1. issue 7. 1996-06-06. PMID:8612196. |
interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis. |
1996-06-06 |
2023-08-12 |
Not clear |
| M P Roth, L Dolbois, N Borot, P Pontarotti, M Clanet, H Coppi. Myelin oligodendrocyte glycoprotein (MOG) gene polymorphisms and multiple sclerosis: no evidence of disease association with MOG. Journal of neuroimmunology. vol 61. issue 2. 1995-11-30. PMID:7593547. |
myelin oligodendrocyte glycoprotein (mog) gene polymorphisms and multiple sclerosis: no evidence of disease association with mog. |
1995-11-30 |
2023-08-12 |
Not clear |
| L J Hinks, S E Price, C R Mason, R J Thompso. Single strand conformation analysis of two genes contained within the first intron of the neurofibromatosis type I gene in patients with multiple sclerosis. Neuropathology and applied neurobiology. vol 21. issue 3. 1995-11-27. PMID:7477728. |
we have examined two closely related genes present in the first intron of the neurofibromatosis type i gene--the oligodendrocyte myelin glycoprotein (omgp) gene and the ecotropic viral integration 2a (evi2a) gene--in 36 patients with multiple sclerosis (ms) and 36 healthy controls. |
1995-11-27 |
2023-08-12 |
Not clear |
| I Mendel, N Kerlero de Rosbo, A Ben-Nu. A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogenic T cells. European journal of immunology. vol 25. issue 7. 1995-08-29. PMID:7621871. |
a predominant response to myelin oligodendrocyte glycoprotein (mog) was recently observed in patients with multiple sclerosis (ms). |
1995-08-29 |
2023-08-12 |
mouse |
| A A Hilton, A J Slavin, D J Hilton, C C Bernar. Characterization of cDNA and genomic clones encoding human myelin oligodendrocyte glycoprotein. Journal of neurochemistry. vol 65. issue 1. 1995-07-26. PMID:7790876. |
myelin oligodendrocyte glycoprotein (mog) is a transmembrane protein expressed only in the cns and is a possible target autoantigen in multiple sclerosis (ms). |
1995-07-26 |
2023-08-12 |
human |