Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
C G Haase, J Guggenmos, U Brehm, M Andersson, T Olsson, M Reindl, J M Schneidewind, U K Zettl, F Heidenreich, T Berger, H Wekerle, R Hohlfeld, C Liningto. The fine specificity of the myelin oligodendrocyte glycoprotein autoantibody response in patients with multiple sclerosis and normal healthy controls. Journal of neuroimmunology. vol 114. issue 1-2. 2001-04-12. PMID:11240035. |
the fine specificity of the myelin oligodendrocyte glycoprotein autoantibody response in patients with multiple sclerosis and normal healthy controls. |
2001-04-12 |
2023-08-12 |
human |
C G Haase, J Guggenmos, U Brehm, M Andersson, T Olsson, M Reindl, J M Schneidewind, U K Zettl, F Heidenreich, T Berger, H Wekerle, R Hohlfeld, C Liningto. The fine specificity of the myelin oligodendrocyte glycoprotein autoantibody response in patients with multiple sclerosis and normal healthy controls. Journal of neuroimmunology. vol 114. issue 1-2. 2001-04-12. PMID:11240035. |
antibodies directed against the extracellular immunoglobulin (ig)-like domain of the myelin oligodendrocyte glycoprotein (mog(igd)) mediate demyelination in experimental autoimmune encephalomyelitis (eae) and are implicated in the immunopathogenesis of multiple sclerosis (ms). |
2001-04-12 |
2023-08-12 |
human |
R C Melcangi, I Cavarretta, V Magnaghi, E Ciusani, A Salmagg. Corticosteroids protect oligodendrocytes from cytokine-induced cell death. Neuroreport. vol 11. issue 18. 2001-03-29. PMID:11192611. |
since oligodendrocyte apoptosis represents an important event in multiple sclerosis and in several demyelinating diseases, the present observations might be considered an interesting background for further researches directed to the possibility of controlling in vivo the death of these cells. |
2001-03-29 |
2023-08-12 |
rat |
A Stefferl, U Brehm, C Liningto. The myelin oligodendrocyte glycoprotein (MOG): a model for antibody-mediated demyelination in experimental autoimmune encephalomyelitis and multiple sclerosis. Journal of neural transmission. Supplementum. issue 58. 2001-02-22. PMID:11128602. |
the myelin oligodendrocyte glycoprotein (mog): a model for antibody-mediated demyelination in experimental autoimmune encephalomyelitis and multiple sclerosis. |
2001-02-22 |
2023-08-12 |
Not clear |
A Niehaus, J Shi, M Grzenkowski, M Diers-Fenger, J Archelos, H P Hartung, K Toyka, W Brück, J Trotte. Patients with active relapsing-remitting multiple sclerosis synthesize antibodies recognizing oligodendrocyte progenitor cell surface protein: implications for remyelination. Annals of neurology. vol 48. issue 3. 2000-10-16. PMID:10976643. |
patients with active relapsing-remitting multiple sclerosis synthesize antibodies recognizing oligodendrocyte progenitor cell surface protein: implications for remyelination. |
2000-10-16 |
2023-08-12 |
Not clear |
F D Shi, K Takeda, S Akira, N Sarvetnick, H G Ljunggre. IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cells. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 6. 2000-10-10. PMID:10975822. |
myelin oligodendrocyte glycoprotein (mog) is a myelin component of the cns and is a candidate autoantigen in multiple sclerosis. |
2000-10-10 |
2023-08-12 |
mouse |
A Chang, A Nishiyama, J Peterson, J Prineas, B D Trap. NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 17. 2000-09-28. PMID:10964946. |
ng2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. |
2000-09-28 |
2023-08-12 |
human |
A Stefferl, A Schubart, M Storch2, A Amini, I Mather, H Lassmann, C Liningto. Butyrophilin, a milk protein, modulates the encephalitogenic T cell response to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 5. 2000-09-19. PMID:10946319. |
experimental autoimmune encephalomyelitis (eae) induced by sensitization with myelin oligodendrocyte glycoprotein (mog) is a t cell-dependent autoimmune disease that reproduces the inflammatory demyelinating pathology of multiple sclerosis. |
2000-09-19 |
2023-08-12 |
rat |
O Schnädelbach, O W Blaschuk, M Symonds, B J Gour, P Doherty, J W Fawcet. N-cadherin influences migration of oligodendrocytes on astrocyte monolayers. Molecular and cellular neurosciences. vol 15. issue 3. 2000-06-19. PMID:10736205. |
these data suggest that cadherins are at least partially responsible for the poor migration-promoting properties of astrocytes and that decreasing cell-cell adhesion might effect repopulation of demyelinated multiple sclerosis lesions by oligodendrocyte progenitors. |
2000-06-19 |
2023-08-12 |
Not clear |
M R Johnson, R E Ferner, M Bobrow, R A Hughe. Detailed analysis of the oligodendrocyte myelin glycoprotein gene in four patients with neurofibromatosis 1 and primary progressive multiple sclerosis. Journal of neurology, neurosurgery, and psychiatry. vol 68. issue 5. 2000-05-30. PMID:10766898. |
detailed analysis of the oligodendrocyte myelin glycoprotein gene in four patients with neurofibromatosis 1 and primary progressive multiple sclerosis. |
2000-05-30 |
2023-08-12 |
human |
R J Franklin, K L Blaschuk, M C Bearchell, L L Prestoz, A Setzu, K M Brindle, C ffrench-Constan. Magnetic resonance imaging of transplanted oligodendrocyte precursors in the rat brain. Neuroreport. vol 10. issue 18. 2000-05-23. PMID:10716241. |
the lack of any markers for oligodendrocyte precursors that can be visualized within the intact cns is a significant barrier to trials of transplantation of these cells which aim to enhance remyelination in multiple sclerosis. |
2000-05-23 |
2023-08-12 |
rat |
A Bitsch, T Kuhlmann, C Da Costa, S Bunkowski, T Polak, W Brüc. Tumour necrosis factor alpha mRNA expression in early multiple sclerosis lesions: correlation with demyelinating activity and oligodendrocyte pathology. Glia. vol 29. issue 4. 2000-04-11. PMID:10652446. |
tumour necrosis factor alpha mrna expression in early multiple sclerosis lesions: correlation with demyelinating activity and oligodendrocyte pathology. |
2000-04-11 |
2023-08-12 |
human |
S Hisahara, T Araki, F Sugiyama, K i Yagami, M Suzuki, K Abe, K Yamamura, J Miyazaki, T Momoi, T Saruta, C C Bernard, H Okano, M Miur. Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination. The EMBO journal. vol 19. issue 3. 2000-03-10. PMID:10654933. |
the mechanisms underlying oligodendrocyte (olg) loss and the precise roles played by olg death in human demyelinating diseases such as multiple sclerosis (ms), and in the rodent model of ms, experimental autoimmune encephalomyelitis (eae), remain to be elucidated. |
2000-03-10 |
2023-08-12 |
mouse |
M Stangel, A Compston, N J Scoldin. Oligodendroglia are protected from antibody-mediated complement injury by normal immunoglobulins ("IVIg"). Journal of neuroimmunology. vol 103. issue 2. 2000-03-10. PMID:10696915. |
antibody and complement deposition have been implicated in the immune attack in some cases of multiple sclerosis (ms), and to investigate the mechanisms of action of ivig, we studied the effect of ivig using the model of complement-mediated cell injury on oligodendroglia in vitro. |
2000-03-10 |
2023-08-12 |
Not clear |
G Wolswij. Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis. Brain : a journal of neurology. vol 123 ( Pt 1). 2000-02-14. PMID:10611125. |
oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis. |
2000-02-14 |
2023-08-12 |
human |
G Wolswij. Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis. Brain : a journal of neurology. vol 123 ( Pt 1). 2000-02-14. PMID:10611125. |
sections of post-mortem multiple sclerosis tissue were therefore immunolabelled with antibodies to galactocerebroside (galc), the first oligodendrocyte-specific molecule to be expressed by differentiating oligodendrocyte precursor cells, and myelin oligodendrocyte glycoprotein (mog), a marker for mature oligodendrocytes. |
2000-02-14 |
2023-08-12 |
human |
G Wolswij. Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis. Brain : a journal of neurology. vol 123 ( Pt 1). 2000-02-14. PMID:10611125. |
the present study thus suggests that the failure of myelin repair in at least some cases of chronic multiple sclerosis is due to (i) the loss of demyelinated oligodendrocytes from lesion areas and (ii) the failure of the oligodendrocyte precursor population to expand and generate new oligodendrocytes. |
2000-02-14 |
2023-08-12 |
human |
C Matute, M Domercq, D J Fogarty, M Pascual de Zulueta, M V Sánchez-Góme. On how altered glutamate homeostasis may contribute to demyelinating diseases of the CNS. Advances in experimental medicine and biology. vol 468. 2000-01-28. PMID:10635022. |
in addition, we present data illustrating that alterations in glutamate homeostasis can be excitotoxic to oligodendroglia and that the tissue lesions caused by overactivation of glutamate receptors resemble those observed in demyelinating diseases such as multiple sclerosis. |
2000-01-28 |
2023-08-12 |
Not clear |
M Reindl, C Linington, U Brehm, R Egg, E Dilitz, F Deisenhammer, W Poewe, T Berge. Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study. Brain : a journal of neurology. vol 122 ( Pt 11). 1999-12-10. PMID:10545390. |
antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study. |
1999-12-10 |
2023-08-12 |
human |
M Reindl, C Linington, U Brehm, R Egg, E Dilitz, F Deisenhammer, W Poewe, T Berge. Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study. Brain : a journal of neurology. vol 122 ( Pt 11). 1999-12-10. PMID:10545390. |
in experimental animal models of multiple sclerosis demyelinating antibody responses are directed against the myelin oligodendrocyte glycoprotein (mog). |
1999-12-10 |
2023-08-12 |
human |