| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sara Veto, Peter Acs, Jan Bauer, Hans Lassmann, Zoltan Berente, Gyorgy Setalo, Gabor Borgulya, Balazs Sumegi, Samuel Komoly, Ferenc Gallyas, Zsolt Ille. Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death. Brain : a journal of neurology. vol 133. issue Pt 3. 2010-04-13. PMID:20157013. |
oligodendrocyte loss and demyelination are major pathological hallmarks of multiple sclerosis. |
2010-04-13 |
2023-08-12 |
Not clear |
| LiPing Liu, Abdelmadjid Belkadi, Lindsey Darnall, Taofang Hu, Caitlin Drescher, Anne C Cotleur, Dolly Padovani-Claudio, Tao He, Karen Choi, Thomas E Lane, Robert H Miller, Richard M Ransohof. CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis. Nature neuroscience. vol 13. issue 3. 2010-03-18. PMID:20154684. |
our findings support a two-hit process of cuprizone-induced demyelination, supporting the idea that multiple sclerosis pathogenesis features extensive oligodendrocyte cell loss. |
2010-03-18 |
2023-08-12 |
mouse |
| Yingru Liu, Yoshio Bando, David Vargas-Lowy, Wassim Elyaman, Samia J Khoury, Tao Huang, Karin Reif, Tanuja Chitni. CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 6. 2010-03-05. PMID:20147531. |
to assess the effects and mechanisms of a cd200r1 agonist administered during the progressive stage of a multiple sclerosis model, we administered cd200r1 agonist (cd200fc) or control igg2a during the chronic phase of disease (days 10-30) in mice with experimental autoimmune encephalomyelitis (eae), induced using myelin oligodendrocyte glycoprotein peptide 35-55 (mog35-55) peptide. |
2010-03-05 |
2023-08-12 |
mouse |
| Ofira Einstein, Yael Friedman-Levi, Nikolaos Grigoriadis, Tamir Ben-Hu. Transplanted neural precursors enhance host brain-derived myelin regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016084. |
in multiple sclerosis lesions resident oligodendrocyte progenitor cells (opcs) are present, but fail to remyelinate. |
2010-01-26 |
2023-08-12 |
mouse |
| Yoh Matsumoto, Il-Kwon Park, Keiko Hiraki, Shin Ohtani, Kuniko Kohyam. Role of pathogenic T cells and autoantibodies in relapse and progression of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis in LEW.1AV1 rats. Immunology. vol 128. issue 1 Suppl. 2010-01-25. PMID:19175799. |
accumulating evidence suggests that t cells and autoantibodies reactive with myelin oligodendrocyte glycoprotein (mog) play a critical role in the pathogenesis of multiple sclerosis (ms). |
2010-01-25 |
2023-08-12 |
rat |
| Carlo Guardiani, Simone Marsili, Piero Procacci, Roberto Liv. Fragment 101-108 of myelin oligodendrocyte glycoprotein: a possible lead compound for multiple sclerosis. Journal of the American Chemical Society. vol 131. issue 47. 2010-01-21. PMID:19891505. |
fragment 101-108 of myelin oligodendrocyte glycoprotein: a possible lead compound for multiple sclerosis. |
2010-01-21 |
2023-08-12 |
Not clear |
| Andrew P D Henderson, Michael H Barnett, John D E Parratt, John W Prinea. Multiple sclerosis: distribution of inflammatory cells in newly forming lesions. Annals of neurology. vol 66. issue 6. 2010-01-18. PMID:20035511. |
cd4 t-cell-dependent macrophage activation directed against a myelin or oligodendrocyte antigen is generally thought to be the mechanism causing myelin destruction in multiple sclerosis (ms). |
2010-01-18 |
2023-08-12 |
Not clear |
| Yueting Zhang, Azeb Tadesse Argaw, Blake T Gurfein, Andleeb Zameer, Brian J Snyder, Changhui Ge, Q Richard Lu, David H Rowitch, Cedric S Raine, Celia F Brosnan, Gareth R Joh. Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 45. 2010-01-06. PMID:19855010. |
in the developing cns, notch1 and its ligand, jagged1, regulate oligodendrocyte differentiation and myelin formation, but their role in repair of demyelinating lesions in diseases such as multiple sclerosis remains unresolved. |
2010-01-06 |
2023-08-12 |
mouse |
| Angelo H All, Piotr Walczak, Gracee Agrawal, Michael Gorelik, Christopher Lee, Nitish V Thakor, Jeff W M Bulte, Douglas A Ker. Effect of MOG sensitization on somatosensory evoked potential in Lewis rats. Journal of the neurological sciences. vol 284. issue 1-2. 2009-12-15. PMID:19423134. |
myelin oligodendrocyte glycoprotein (mog) is commonly used as an immunogen to induce an immune response against endogenous myelin, thereby modeling multiple sclerosis in rodents. |
2009-12-15 |
2023-08-12 |
rat |
| Silvia Rossi, Roberto Furlan, Valentina De Chiara, Alessandra Musella, Temistocle Lo Giudice, Giorgia Mataluni, Francesca Cavasinni, Cristina Cantarella, Giorgio Bernardi, Luca Muzio, Alessandro Martorana, Gianvito Martino, Diego Centonz. Exercise attenuates the clinical, synaptic and dendritic abnormalities of experimental autoimmune encephalomyelitis. Neurobiology of disease. vol 36. issue 1. 2009-12-07. PMID:19591937. |
in the present study, we evaluated the clinical, synaptic and neuropathological effects of voluntary wheel running in mice with myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae), a model of multiple sclerosis. |
2009-12-07 |
2023-08-12 |
mouse |
| Qing Li, Kristine Nacion, Hong Bu, Feng Li. The complement inhibitor FUT-175 suppresses T cell autoreactivity in experimental autoimmune encephalomyelitis. The American journal of pathology. vol 175. issue 2. 2009-10-27. PMID:19608865. |
several recent studies have shown that interacting antigen presenting cells and/or t cells produced complement activation products c5a and c3a, are integrally involved in t-cell activation, and promote the generation of myelin oligodendrocyte glycoprotein (mog(35-55))-specific interferon-gamma and interleukin-17-producing t cells in experimental autoimmune encephalomyelitis, a rodent model of multiple sclerosis. |
2009-10-27 |
2023-08-12 |
mouse |
| Michael Thorne, Craig S Moore, George S Robertso. Lack of TIMP-1 increases severity of experimental autoimmune encephalomyelitis: Effects of darbepoetin alfa on TIMP-1 null and wild-type mice. Journal of neuroimmunology. vol 211. issue 1-2. 2009-07-07. PMID:19428125. |
multiple sclerosis (ms) and experimental autoimmune encephalomyelitis (eae) are both characterized by the infiltration of myelin-reactive t cells that trigger oligodendrocyte death associated with axonal loss and neurodegeneration in the cns. |
2009-07-07 |
2023-08-12 |
mouse |
| Melanie Thessen Hedreul, Alan Gillett, Tomas Olsson, Maja Jagodic, Robert A Harri. Characterization of Multiple Sclerosis candidate gene expression kinetics in rat experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 210. issue 1-2. 2009-07-06. PMID:19269041. |
we thus aimed to determine the kinetic expression of several multiple sclerosis (ms) candidate genes in the myelin oligodendrocyte glycoprotein (mog)-induced rat experimental autoimmune encephalomyelitis (eae) model using susceptible da and resistant pvg inbred strains. |
2009-07-06 |
2023-08-12 |
human |
| Sha Mi, Robert H Miller, Wei Tang, Xinhua Lee, Bing Hu, Wutain Wu, Yiping Zhang, Christopher B Shields, Yongjie Zhang, Steven Miklasz, Diana Shea, Jeff Mason, Robin J M Franklin, Benxiu Ji, Zhaohui Shao, Alain Chédotal, Frederic Bernard, Aude Roulois, Janfeng Xu, Vincent Jung, Blake Pepinsk. Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells. Annals of neurology. vol 65. issue 3. 2009-04-23. PMID:19334062. |
repair of demyelinated axons in diseases such as multiple sclerosis requires activation of the myelination program in existing or newly recruited oligodendrocyte precursor cells (opcs). |
2009-04-23 |
2023-08-12 |
Not clear |
| Jin Nakahara, Kohsuke Kanekura, Mikiro Nawa, Sadakazu Aiso, Norihiro Suzuk. Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis. The Journal of clinical investigation. vol 119. issue 1. 2009-03-10. PMID:19104151. |
abnormal expression of tip30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis. |
2009-03-10 |
2023-08-12 |
rat |
| Sven G Meuth, Tatjana Kanyshkov, Nico Melzer, Stefan Bittner, Bernd C Kieseier, Thomas Budde, Heinz Wiend. Altered neuronal expression of TASK1 and TASK3 potassium channels in rodent and human autoimmune CNS inflammation. Neuroscience letters. vol 446. issue 2-3. 2009-02-27. PMID:18824070. |
multiple sclerosis (ms) and its animal model experimental autoimmune encephalomyelitis (eae) are characterized by t cell-mediated autoimmune inflammation of the central nervous system (cns) leading to oligodendrocyte loss and demyelination accompanied by neuronal cell death. |
2009-02-27 |
2023-08-12 |
human |
| P A McComb. Recombinant EPF/chaperonin 10 promotes the survival of O4-positive pro-oligodendrocytes prepared from neonatal rat brain. Cell stress & chaperones. vol 13. issue 4. 2009-02-09. PMID:18465204. |
we aimed to assess the effects of cpn 10 on cells of the oligodendrocyte lineage because oligodendrocytes are the brain cells that produce myelin and that are depleted in multiple sclerosis. |
2009-02-09 |
2023-08-12 |
rat |
| Asa Andersson, Magnus Isaksson, Judit Wefer, Anna Norling, Amilcar Flores-Morales, Fredrik Rorsman, Olle Kämpe, Robert A Harris, Anna Lobel. Impaired autoimmune T helper 17 cell responses following DNA vaccination against rat experimental autoimmune encephalomyelitis. PloS one. vol 3. issue 11. 2008-12-23. PMID:18997868. |
we have previously shown that vaccination with dna encoding the encephalitogenic peptide myelin oligodendrocyte glycoprotein (mog)(91-108) (pmog) suppresses mog(91-108)-induced rat experimental autoimmune encephalomyelitis (eae), a model for human multiple sclerosis (ms). |
2008-12-23 |
2023-08-12 |
human |
| H Wang, K L Munger, M Reindl, E J O'Reilly, L I Levin, T Berger, A Ascheri. Myelin oligodendrocyte glycoprotein antibodies and multiple sclerosis in healthy young adults. Neurology. vol 71. issue 15. 2008-10-31. PMID:18753473. |
myelin oligodendrocyte glycoprotein antibodies and multiple sclerosis in healthy young adults. |
2008-10-31 |
2023-08-12 |
Not clear |
| H Wang, K L Munger, M Reindl, E J O'Reilly, L I Levin, T Berger, A Ascheri. Myelin oligodendrocyte glycoprotein antibodies and multiple sclerosis in healthy young adults. Neurology. vol 71. issue 15. 2008-10-31. PMID:18753473. |
it remains uncertain whether the presence of serum anti-myelin oligodendrocyte glycoprotein (mog) antibodies in healthy individuals contributes to predict their risk of developing multiple sclerosis (ms). |
2008-10-31 |
2023-08-12 |
Not clear |