| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lynn A Legg, Russel Tilney, Cheng-Fang Hsieh, Simiao Wu, Erik Lundström, Ann-Sofie Rudberg, Mansur A Kutlubaev, Martin Dennis, Babak Soleimani, Amanda Barugh, Maree L Hackett, Graeme J Hankey, Gillian E Mea. Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. The Cochrane database of systematic reviews. vol 2019. issue 11. 2020-04-23. PMID:31769878. |
selective serotonin reuptake inhibitors (ssris) have been used for many years to manage depression and other mood disorders after stroke. |
2020-04-23 |
2023-08-13 |
Not clear |
| Mehdi Ghasemi, Joshua Claunch, Kathy Ni. Pathologic role of nitrergic neurotransmission in mood disorders. Progress in neurobiology. vol 173. 2020-02-17. PMID:29890213. |
the hypothesis has arisen from several observations including (i) altered no levels in patients with mood disorders; (ii) antidepressant effects of no signaling blockers in both clinical and pre-clinical studies; (iii) interaction between conventional antidepressants/mood stabilizers and no signaling modulators in several biochemical and behavioral studies; (iv) biochemical and physiological evidence of interaction between monoaminergic (serotonin, noradrenaline, and dopamine) system and no signaling; (v) interaction between neurotrophic factors and no signaling in mood regulation and neuroprotection; and finally (vi) a crucial role for no signaling in the inflammatory processes involved in pathophysiology of mood disorders. |
2020-02-17 |
2023-08-13 |
Not clear |
| Lawson R Wulsi. Another Step Toward Clarifying the Benefits and Burdens of Selective Serotonin Reuptake Inhibitors. Psychosomatic medicine. vol 81. issue 7. 2020-01-08. PMID:31343580. |
selective serotonin reuptake inhibitors (ssris) have substantial beneficial effects for the treatment of major depressive mood disorders and other conditions but can also result in unwanted clinical outcomes. |
2020-01-08 |
2023-08-13 |
Not clear |
| Steiner, Yatham, Coote, Wilkins, Lepag. Serotonergic dysfunction in women with pure premenstrual dysphoric disorder: is the fenfluramine challenge test still relevant? Psychiatry research. vol 87. issue 2-3. 2019-11-20. PMID:10579544. |
the purpose of this study was to ascertain the role of 5-ht in premenstrual dysphoric disorder (pmdd) by measuring: (1) prl and cortisol (cort) responses to fen; and (2) platelet 3h-imipramine binding levels, in females with pure pmdd (without a past or present comorbid mood disorder) in comparison to healthy controls. |
2019-11-20 |
2023-08-12 |
Not clear |
| Pau Celada, M. Victoria Puig, Raúl Martín-Ruiz, Josep M. Casanovas, Francesc Artiga. Control of the serotonergic system by the medial prefrontal cortex: potential role in the etiology of PTSD and depressive disorders. Neurotoxicity research. vol 4. issue 5-6. 2019-11-20. PMID:12754155. |
serotonergic neurons of the midbrain rapbe nuclei innervate the prefrontal cortex and are the cellular target for drugs used to treat mood disorders such as the selective serotonin (5-ht) reuptake inhibitors. |
2019-11-20 |
2023-08-12 |
Not clear |
| Bettina Hornboll, Julian Macoveanu, Ayna Nejad, James Rowe, Rebecca Elliott, Gitte M Knudsen, Hartwig R Siebner, Olaf B Paulso. Neuroticism predicts the impact of serotonin challenges on fear processing in subgenual anterior cingulate cortex. Scientific reports. vol 8. issue 1. 2019-10-18. PMID:30559408. |
the personality trait neuroticism is associated with increased vulnerability to anxiety and mood disorders, conditions linked with abnormal serotonin neurotransmission and emotional processing. |
2019-10-18 |
2023-08-13 |
human |
| Ann E Klega, Jennifer Tickal Keehbauc. Stimulant and Designer Drug Use: Primary Care Management. American family physician. vol 98. issue 2. 2019-08-01. PMID:30215997. |
adverse effects include serotonin syndrome, hyponatremia, long-term memory impairment, and mood disorders. |
2019-08-01 |
2023-08-13 |
Not clear |
| Eszter Bogi, Kristina Belovicová, Eduard Ujhazy, Mojmír Mach, Romana Koprdova, Ludmila Zilava, Alexandra Garafová, Daniela Jezova, Michal Dubovick. Perinatal exposure to venlafaxine leads to lower anxiety and depression-like behavior in the adult rat offspring. Behavioural pharmacology. vol 29. issue 5. 2019-07-31. PMID:29561291. |
venlafaxine, a representative of serotonin and noradrenaline reuptake inhibitors, is used to treat a wide spectrum of mood disorders. |
2019-07-31 |
2023-08-13 |
rat |
| Francis Delicata, Cristiano Bombardi, Massimo Pierucci, Roberto Di Maio, Philippe De Deurwaerdère, Giuseppe Di Giovann. Preferential modulation of the lateral habenula activity by serotonin-2A rather than -2C receptors: Electrophysiological and neuroanatomical evidence. CNS neuroscience & therapeutics. vol 24. issue 8. 2019-05-29. PMID:29479825. |
serotonergic (5-ht) modulation of the lateral habenula (lhb) activity is central in normal and pathologic conditions such as mood disorders. |
2019-05-29 |
2023-08-13 |
Not clear |
| Rachel A Ungar, Neelam Giri, Maryland Pao, Payal P Khincha, Weiyin Zhou, Blanche P Alter, Sharon A Savag. Complex phenotype of dyskeratosis congenita and mood dysregulation with novel homozygous RTEL1 and TPH1 variants. American journal of medical genetics. Part A. vol 176. issue 6. 2019-05-21. PMID:29696773. |
a homozygous, missense variant in tryptophan hydroxylase 1 may be clinically important as this gene encodes the rate limiting step in serotonin biosynthesis, a biologic pathway connected with mood disorders. |
2019-05-21 |
2023-08-13 |
human |
| Peter J Holmberg, Grace Arteaga, Brenda M Schiltz, James Homm. Sertraline-Induced Rhabdomyolysis, Trismus, and Cardiac Arrest in a Child. Pediatrics. vol 142. issue 4. 2019-05-15. PMID:30194278. |
selective serotonin reuptake inhibitors are a commonly used and often effective class of medications in the treatment of mood disorders such as anxiety and depression. |
2019-05-15 |
2023-08-13 |
Not clear |
| Huang-Yu Chang, Shu-Ling Chen, Meng-Ru Shen, Mei-Lang Kung, Lee-Ming Chuang, Yun-Wen Che. Selective serotonin reuptake inhibitor, fluoxetine, impairs E-cadherin-mediated cell adhesion and alters calcium homeostasis in pancreatic beta cells. Scientific reports. vol 7. issue 1. 2019-05-13. PMID:28615694. |
selective serotonin reuptake inhibitors (ssris) are the most commonly prescribed drugs for mood disorders. |
2019-05-13 |
2023-08-13 |
Not clear |
| Hera Wu, Travis H Denna, Jordan N Storkersen, Valerie A Gerriet. Beyond a neurotransmitter: The role of serotonin in inflammation and immunity. Pharmacological research. vol 140. 2019-05-13. PMID:29953943. |
in addition, there is emerging evidence of a possible connection between t cells, serotonin and mood disorders. |
2019-05-13 |
2023-08-13 |
Not clear |
| Hera Wu, Travis H Denna, Jordan N Storkersen, Valerie A Gerriet. Beyond a neurotransmitter: The role of serotonin in inflammation and immunity. Pharmacological research. vol 140. 2019-05-13. PMID:29953943. |
how 5-ht interacts with the peripheral immune system and if this signaling is associated with behavioral phenotypes found in mood disorders like major depressive disorder (mdd) is not well understood. |
2019-05-13 |
2023-08-13 |
Not clear |
| Paulina Jaworska-Andryszewska, Janusz K Rybakowsk. Childhood trauma in mood disorders: Neurobiological mechanisms and implications for treatment. Pharmacological reports : PR. vol 71. issue 1. 2019-04-03. PMID:30544098. |
interaction of several genes with childhood trauma to produce pathological, clinical phenomena in adulthood has been demonstrated, the most important in this respect being the serotonin transporter gene and the fkbp5 gene playing an important role in the pathogenesis of mood disorders. |
2019-04-03 |
2023-08-13 |
Not clear |
| D Caroline Blanchard, Ksenia Meyz. Risk assessment and serotonin: Animal models and human psychopathologies. Behavioural brain research. vol 357-358. 2019-03-29. PMID:28705471. |
findings of parallel effects of serotonin systems in ra would support a view that it may provide a useful behavioral endophenotype for translational research on mood disorders. |
2019-03-29 |
2023-08-13 |
mouse |
| Mary Gemmel, Sonsoles De Lacalle, Sophia C Mort, Lesley A Hill, Thierry D Charlier, Jodi L Pawlusk. Perinatal fluoxetine has enduring sexually differentiated effects on neurobehavioral outcomes related to social behaviors. Neuropharmacology. vol 144. 2019-03-04. PMID:30326241. |
selective serotonin reuptake inhibitor medications (ssris) are prescribed to up to 10% of pregnant women to treat maternal mood disorders. |
2019-03-04 |
2023-08-13 |
rat |
| Silvia Vincentiis, Juliana Alcantara, Patricia Rzezak, Daniel S Kerr, Wagner F Gattaz, Helio van der Linden, Bernardo Dos Santos, Sebastiao E Melo-Souza, Francisco Arruda, Paulo Ragazzo, Tiffany Chaim-Avancini, Mauricio H Serpa, Fernando Fernandes, Ricardo A Moreno, Geraldo Busatto, Ruda Alessi, Renata Demarque, Kette D Valent. Genetic polymorphisms of the 5HT receptors are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. Epilepsy & behavior : E&B. vol 83. 2019-02-25. PMID:29709878. |
the primary goal of this study was to determine the possible association between polymorphisms of genes encoding the serotonin receptors 5ht1a (rs6295), 5ht1b (rs6296), and 5ht2c (rs6318) and the presence of mood disorders in patients with tle-hs. |
2019-02-25 |
2023-08-13 |
Not clear |
| Eric Brown, Conor J Mc Veigh, Leilani Santos, Martina Gogarty, Heidi Kaastrup Müller, Betina Elfving, David J Brayden, Jana Haas. TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis. Neuropharmacology. vol 137. 2019-02-20. PMID:29723540. |
the serotonin transporter (sert) facilitates high affinity reuptake of 5-ht from the extracellular fluid and dysregulation of transporter function has been implicated in a range of mood disorders including depression. |
2019-02-20 |
2023-08-13 |
mouse |
| Jessica A Babb, Sofia E Linnros, Kathryn G Common. Evidence for intact 5-HT Neuropharmacology. vol 141. 2019-02-13. PMID:30170082. |
evidence for intact 5-ht serotonin (5-ht) neurons are strongly implicated in mood disorders such as depression and are importantly regulated by feedback inhibition mediated by 5-ht |
2019-02-13 |
2023-08-13 |
Not clear |