| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hyeon Son, Mounira Banasr, Miyeon Choi, Seung Yeon Chae, Pawel Licznerski, Boyoung Lee, Bhavya Voleti, Nanxin Li, Ashley Lepack, Neil M Fournier, Ka Rim Lee, In Young Lee, Juhyun Kim, Joung-Hun Kim, Yong Ho Kim, Sung Jun Jung, Ronald S Duma. Neuritin produces antidepressant actions and blocks the neuronal and behavioral deficits caused by chronic stress. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 28. 2012-10-05. PMID:22733766. |
decreased neuronal dendrite branching and plasticity of the hippocampus, a limbic structure implicated in mood disorders, is thought to contribute to the symptoms of depression. |
2012-10-05 |
2023-08-12 |
Not clear |
| Peter C Williamson, John M Allma. A framework for interpreting functional networks in schizophrenia. Frontiers in human neuroscience. vol 6. 2012-10-02. PMID:22737116. |
alternatively, it is proposed that schizophrenia arises from a uniquely human brain network associated with directed effort including the dorsal anterior and posterior cingulate cortex (pcc), auditory cortex, and hippocampus while mood disorders arise from a different brain network associated with emotional encoding including the ventral anterior cingulate cortex (acc), orbital frontal cortex, and amygdala. |
2012-10-02 |
2023-08-12 |
human |
| Hans-Gert Bernstein, Claudia Stich, Kristin Jäger, Henrik Dobrowolny, Martin Wick, Johann Steiner, Rüdiger Veh, Bernhard Bogerts, Gregor Laub. Agmatinase, an inactivator of the putative endogenous antidepressant agmatine, is strongly upregulated in hippocampal interneurons of subjects with mood disorders. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21803059. |
agmatinase, an inactivator of the putative endogenous antidepressant agmatine, is strongly upregulated in hippocampal interneurons of subjects with mood disorders. |
2012-08-13 |
2023-08-12 |
human |
| Jing Feng, Qi Wu, Dan Zhang, Bao-yuan Che. Hippocampal impairments are associated with intermittent hypoxia of obstructive sleep apnea. Chinese medical journal. vol 125. issue 4. 2012-08-03. PMID:22490498. |
to the central nervous system, osa causes behavioral and neuropsychologic deficits including daytime sleepiness, depression, impaired memory, mood disorders, cognition deficiencies, language comprehension and expression deficiencies, all of which are compatible with impaired hippocampal function. |
2012-08-03 |
2023-08-12 |
Not clear |
| A Novati, H J Hulshof, J M Koolhaas, P J Lucassen, P Meerl. Chronic sleep restriction causes a decrease in hippocampal volume in adolescent rats, which is not explained by changes in glucocorticoid levels or neurogenesis. Neuroscience. vol 190. 2012-07-05. PMID:21718758. |
thus, our results indicate that insufficient sleep may be a causal factor in the reductions of hippocampal volume that have been reported in human sleep disorders and mood disorders. |
2012-07-05 |
2023-08-12 |
human |
| Jenifer Juranek, Chad P Johnson, Mary R Prasad, Larry A Kramer, Ann Saunders, Pauline A Filipek, Paul R Swank, Charles S Cox, Linda Ewing-Cobb. Mean diffusivity in the amygdala correlates with anxiety in pediatric TBI. Brain imaging and behavior. vol 6. issue 1. 2012-06-12. PMID:21979818. |
in the present study, we integrated anatomical and diffusion tensor neuroimaging to investigate structural properties of the amygdala and hippocampus, gray matter regions implicated in anxiety and mood disorders. |
2012-06-12 |
2023-08-12 |
Not clear |
| Justin S Catches, Jian Xu, Anis Contracto. Genetic ablation of the GluK4 kainate receptor subunit causes anxiolytic and antidepressant-like behavior in mice. Behavioural brain research. vol 228. issue 2. 2012-05-23. PMID:22203159. |
these studies demonstrate a clear anxiolytic and antidepressant phenotype associated with ablation of grik4 and a parallel disruption in hippocampal plasticity, providing support for the importance of this receptor subunit in mood disorders. |
2012-05-23 |
2023-08-12 |
mouse |
| Yann Quidé, Anke B Witteveen, Wissam El-Hage, Dick J Veltman, Miranda Olf. Differences between effects of psychological versus pharmacological treatments on functional and morphological brain alterations in anxiety disorders and major depressive disorder: a systematic review. Neuroscience and biobehavioral reviews. vol 36. issue 1. 2012-04-19. PMID:21963442. |
the most prevalent mental disorders, anxiety and mood disorders, are associated with both functional and morphological brain changes that commonly involve the 'fear network' including the (medial) prefrontal cortex, hippocampus and amygdala. |
2012-04-19 |
2023-08-12 |
Not clear |
| V F Low, M Dragunow, L J Tippett, R L M Faull, M A Curti. No change in progenitor cell proliferation in the hippocampus in Huntington's disease. Neuroscience. vol 199. 2012-04-06. PMID:21946006. |
we hypothesized that hd cases with mainly mood symptomatology would show a greater change in hippocampal proliferation, which has previously been implicated in mood disorders such as depression. |
2012-04-06 |
2023-08-12 |
mouse |
| R Crupi, A Marino, S Cuzzocre. New therapeutic strategy for mood disorders. Current medicinal chemistry. vol 18. issue 28. 2012-02-29. PMID:21861822. |
the heterogeneity of mood disorders indicates that its origin may lie in dysfunction of multiple brain regions (amygdala, nucleus accumbens, hippocampus, prefrontal cortex and cingulate cortex). |
2012-02-29 |
2023-08-12 |
Not clear |
| R Crupi, A Marino, S Cuzzocre. New therapeutic strategy for mood disorders. Current medicinal chemistry. vol 18. issue 28. 2012-02-29. PMID:21861822. |
in this regard, focusing on neurogenesis and neuroplasticity processes in experimental models is particularly interesting for the understanding of the pathophysiology of mood disorders and should define the role of adult-born neurons in hippocampal physiology. |
2012-02-29 |
2023-08-12 |
Not clear |
| T Panigada, R-D Gosseli. Behavioural alteration in chronic pain: are brain glia involved? Medical hypotheses. vol 77. issue 4. 2011-12-29. PMID:21741179. |
indeed, in mood disorders (unipolar depression, anxiety disorders, autism or schizophrenia) glial changes in brain regions involved in mood control (prefrontal and cingulate cortices, amygdala and the hippocampus) have been recurrently described. |
2011-12-29 |
2023-08-12 |
Not clear |
| Claudia A Grillo, Gerardo G Piroli, Kris F Kaigler, Steven P Wilson, Marlene A Wilson, Lawrence P Reaga. Downregulation of hypothalamic insulin receptor expression elicits depressive-like behaviors in rats. Behavioural brain research. vol 222. issue 1. 2011-09-02. PMID:21458499. |
collectively, these data support the hypothesis for an increased risk for mood disorders in obesity, which may be related to decreased expression of hippocampal and amygdalar bdnf. |
2011-09-02 |
2023-08-12 |
rat |
| Vitaly Khaindrava, Pascal Salin, Christophe Melon, Michael Ugrumov, Lydia Kerkerian-Le-Goff, Annie Daszut. High frequency stimulation of the subthalamic nucleus impacts adult neurogenesis in a rat model of Parkinson's disease. Neurobiology of disease. vol 42. issue 3. 2011-08-23. PMID:21296669. |
here, we looked for possible stn-hfs-induced changes on adult brain neurogenesis in the hippocampus and olfactory bulb that may be related to non-motor deficits associated to pd, such as mood disorders and olfaction deficits. |
2011-08-23 |
2023-08-12 |
rat |
| Mia Thompson Ray, Cynthia Shannon Weickert, Eugene Wyatt, Maree J Webste. Decreased BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders. Journal of psychiatry & neuroscience : JPN. vol 36. issue 3. 2011-08-15. PMID:21223646. |
decreased bdnf, trkb-tk+ and gad67 mrna expression in the hippocampus of individuals with schizophrenia and mood disorders. |
2011-08-15 |
2023-08-12 |
Not clear |
| Cortney A Turner, Sarah M Clinton, Robert C Thompson, Stanley J Watson, Huda Aki. Fibroblast growth factor-2 (FGF2) augmentation early in life alters hippocampal development and rescues the anxiety phenotype in vulnerable animals. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 19. 2011-07-15. PMID:21518861. |
individuals with mood disorders exhibit alterations in the fibroblast growth factor system, including reduced hippocampal fibroblast growth factor-2 (fgf2). |
2011-07-15 |
2023-08-12 |
rat |
| Suk-Yu Yau, Benson Wui-Man Lau, Kwok-Fai S. Adult hippocampal neurogenesis: a possible way how physical exercise counteracts stress. Cell transplantation. vol 20. issue 1. 2011-06-23. PMID:20887683. |
recently, it is suggested that altered hippocampal neurogenesis is related to pathophysiology of mood disorders and mechanism of antidepressant treatments. |
2011-06-23 |
2023-08-12 |
Not clear |
| Stefan M Gold, Kyle C Kern, Mary-Frances O'Connor, Michael J Montag, Aileen Kim, Ye S Yoo, Barbara S Giesser, Nancy L Sicott. Smaller cornu ammonis 2-3/dentate gyrus volumes and elevated cortisol in multiple sclerosis patients with depressive symptoms. Biological psychiatry. vol 68. issue 6. 2011-01-20. PMID:20646680. |
the hippocampus is likely involved in mood disorders, but in vivo evidence for the role of anatomically distinct hippocampal subregions is lacking. |
2011-01-20 |
2023-08-12 |
Not clear |
| b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Stefan Bren\\xc3\\xa. The antidepressant effects of running and escitalopram are associated with levels of hippocampal NPY and Y1 receptor but not cell proliferation in a rat model of depression. Hippocampus. vol 20. issue 7. 2010-09-28. PMID:19623606.' |
in this study, we compared the effects of three long-term antidepressant treatments: escitalopram, voluntary running, and their combination on hippocampal cell proliferation, npy and the npy-y1 receptor mrnas, targets assumed to be important for hippocampal plasticity and mood disorders. |
2010-09-28 |
2023-08-12 |
rat |
| Aet Alttoa, Kadri Kõiv, Timothy A Hinsley, Andrew Brass, Jaanus Harr. Differential gene expression in a rat model of depression based on persistent differences in exploratory activity. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 20. issue 5. 2010-06-14. PMID:19854624. |
we investigated the genome-wide gene expression patterns in an animal model of depression that separates wistar rats belonging into clusters of persistently high anxiety/low motivation to explore and low anxiety/high motivation to explore (low explorers and high explorers, le and he, respectively), in three brain regions previously implicated in mood disorders (raphe, hippocampus and the frontal cortex). |
2010-06-14 |
2023-08-12 |
rat |