| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carla Toro, J F W Deaki. NMDA receptor subunit NRI and postsynaptic protein PSD-95 in hippocampus and orbitofrontal cortex in schizophrenia and mood disorder. Schizophrenia research. vol 80. issue 2-3. 2006-05-02. PMID:16140506. |
we have used immunoautoradiographical techniques to assess the expression of the obligatory nmda receptor subunit nr1 and an associated post-synaptic density protein psd-95 in the hippocampal dentate gyrus and orbitofrontal cortex (ofc) in schizophrenia and mood disorder. |
2006-05-02 |
2023-08-12 |
Not clear |
| Tibor Hajszan, Neil J MacLusk. Neurologic links between epilepsy and depression in women: is hippocampal neuroplasticity the key? Neurology. vol 66. issue 6 Suppl 3. 2006-04-17. PMID:16567737. |
the hippocampus plays a critical role in both seizure activity and mood disorders, which suggests that pathology in this area of the brain might provide a link between epilepsy and depression. |
2006-04-17 |
2023-08-12 |
Not clear |
| Annie Daszuta, Mounira Ban, Amélie Soumier, Micheline Hery, Elisabeth Mocae. [Depression and neuroplasticity: implication of serotoninergic systems]. Therapie. vol 60. issue 5. 2006-03-28. PMID:16433011. |
although the mechanisms underlying such effects are still unknown, these data reinforce the view that changes in hippocampal neurogenesis might belong to the cellular correlates of mood disorders. |
2006-03-28 |
2023-08-12 |
Not clear |
| D Peleg-Raibstein, M A Pezze, B Ferger, W-N Zhang, C A Murphy, J Feldon, T Bas. Activation of dopaminergic neurotransmission in the medial prefrontal cortex by N-methyl-d-aspartate stimulation of the ventral hippocampus in rats. Neuroscience. vol 132. issue 1. 2005-07-20. PMID:15780480. |
moreover, it indicates that aberrant hippocampal activity, as found in neuropsychiatric diseases, such as schizophrenia and mood disorders, may contribute to disruption of certain cognitive and emotional functions which are extremely sensitive to imbalanced prefrontal dopamine transmission. |
2005-07-20 |
2023-08-12 |
rat |
| Bruce S McEwe. Glucocorticoids, depression, and mood disorders: structural remodeling in the brain. Metabolism: clinical and experimental. vol 54. issue 5 Suppl 1. 2005-07-05. PMID:15877308. |
in long-term depressive illness, the hippocampus and prefrontal cortex undergo atrophy, whereas the amygdala is hyperactive in anxiety and mood disorders and may undergo a biphasic change in structure--increasing in size in acute depression and shrinking on long-term depression. |
2005-07-05 |
2023-08-12 |
Not clear |
| Tibor Hajszan, Neil J MacLusky, Csaba Lerant. Short-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus. The European journal of neuroscience. vol 21. issue 5. 2005-05-27. PMID:15813939. |
hippocampal synaptic remodelling might provide a potential mechanism to explain certain aspects of antidepressant therapy and mood disorders, especially those associated with changes in reproductive state in women, that cannot be reconciled adequately with current theories for depression. |
2005-05-27 |
2023-08-12 |
rat |
| Djoher Nora Abrous, Muriel Koehl, Michel Le Moa. Adult neurogenesis: from precursors to network and physiology. Physiological reviews. vol 85. issue 2. 2005-04-14. PMID:15788705. |
finally, we review the progress accomplished in implicating neurogenesis in hippocampal functioning under physiological conditions and in the development of hippocampal-related pathologies such as epilepsy, mood disorders, and addiction. |
2005-04-14 |
2023-08-12 |
Not clear |
| A Vyas, A G Pillai, S Chattarj. Recovery after chronic stress fails to reverse amygdaloid neuronal hypertrophy and enhanced anxiety-like behavior. Neuroscience. vol 128. issue 4. 2005-02-04. PMID:15464275. |
these findings on persistent dendritic remodeling in the amygdala, in addition to highlighting important differences with hippocampal structural plasticity, may provide a cellular basis for examining anxiety and mood disorders triggered by chronic stress. |
2005-02-04 |
2023-08-12 |
rat |
| Linda E Haynes, Dave Barber, Ian J Mitchel. Chronic antidepressant medication attenuates dexamethasone-induced neuronal death and sublethal neuronal damage in the hippocampus and striatum. Brain research. vol 1026. issue 2. 2005-01-31. PMID:15488477. |
dexamethasone, a synthetic corticosteroid, which can induce a range of mood disorders including depression and affective psychosis, is toxic to specific hippocampal and striatal neuronal populations. |
2005-01-31 |
2023-08-12 |
rat |
| Torsten M Madsen, Damaris D Yeh, Gerald W Valentine, Ronald S Duma. Electroconvulsive seizure treatment increases cell proliferation in rat frontal cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 1. 2005-01-26. PMID:15383831. |
since mood disorders are likely to involve brain regions in addition to hippocampus, particularly the frontal cortex, it is likely that antidepressant treatments produce cellular changes in these brain regions as well. |
2005-01-26 |
2023-08-12 |
rat |
| Giuseppe Blasi, Alessandro Bertolino, Flora Brudaglio, Domenico Sciota, Mario Altamura, Nicola Antonucci, Tommaso Scarabino, Daniel R Weinberger, Marcello Nardin. Hippocampal neurochemical pathology in patients at first episode of affective psychosis: a proton magnetic resonance spectroscopic imaging study. Psychiatry research. vol 131. issue 2. 2004-12-22. PMID:15313516. |
while several studies have suggested a relationship between the hippocampus and psychosis in schizophrenia, fewer studies have specifically investigated the presence of psychosis in mood disorders from a neurobiological perspective. |
2004-12-22 |
2023-08-12 |
human |
| Giuseppe Blasi, Alessandro Bertolino, Flora Brudaglio, Domenico Sciota, Mario Altamura, Nicola Antonucci, Tommaso Scarabino, Daniel R Weinberger, Marcello Nardin. Hippocampal neurochemical pathology in patients at first episode of affective psychosis: a proton magnetic resonance spectroscopic imaging study. Psychiatry research. vol 131. issue 2. 2004-12-22. PMID:15313516. |
the present proton magnetic resonance spectroscopic imaging (1h-mrsi) study assessed neuronal integrity (as assessed with n-acetylaspartate, naa) in the hippocampus of patients with a first episode of mood disorders with psychotic symptoms. |
2004-12-22 |
2023-08-12 |
human |
| Giuseppe Blasi, Alessandro Bertolino, Flora Brudaglio, Domenico Sciota, Mario Altamura, Nicola Antonucci, Tommaso Scarabino, Daniel R Weinberger, Marcello Nardin. Hippocampal neurochemical pathology in patients at first episode of affective psychosis: a proton magnetic resonance spectroscopic imaging study. Psychiatry research. vol 131. issue 2. 2004-12-22. PMID:15313516. |
therefore, hippocampal neuronal abnormalities are present at the onset of mood disorders with psychotic symptoms. |
2004-12-22 |
2023-08-12 |
human |
| Poul Videbech, Barbara Ravnkild. Hippocampal volume and depression: a meta-analysis of MRI studies. The American journal of psychiatry. vol 161. issue 11. 2004-12-02. PMID:15514393. |
the authors performed a systematic review and meta-analysis of volumetric studies of the hippocampus in patients with mood disorders. |
2004-12-02 |
2023-08-12 |
Not clear |
| J L Fudg. Bcl-2 immunoreactive neurons are differentially distributed in subregions of the amygdala and hippocampus of the adult macaque. Neuroscience. vol 127. issue 2. 2004-11-09. PMID:15262342. |
the amygdala and hippocampus are key limbic structures of the temporal lobe, and are implicated in the pathology of mood disorders. |
2004-11-09 |
2023-08-12 |
monkey |
| Kenji Hashimoto, Eiji Shimizu, Masaomi Iy. Critical role of brain-derived neurotrophic factor in mood disorders. Brain research. Brain research reviews. vol 45. issue 2. 2004-08-18. PMID:15145621. |
furthermore, bdnf protects against stress-induced neuronal damage, and it might affect neurogenesis in the hippocampus, which is thought to be involved in the pathogenesis of mood disorders. |
2004-08-18 |
2023-08-12 |
Not clear |
| Ramin S Hastings, Ramin V Parsey, Maria A Oquendo, Victoria Arango, J John Man. Volumetric analysis of the prefrontal cortex, amygdala, and hippocampus in major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 5. 2004-05-25. PMID:14997169. |
sex may affect volumetric deficits in amygdala and anterior cingulate cortex in mood disorders, but no effects were found in the hippocampus or opfc. |
2004-05-25 |
2023-08-12 |
human |
| Barbara Vollmayr, Claudia Simonis, Silja Weber, Peter Gass, Fritz Hen. Reduced cell proliferation in the dentate gyrus is not correlated with the development of learned helplessness. Biological psychiatry. vol 54. issue 10. 2003-12-29. PMID:14625145. |
a plethora of indirect findings suggests that mood disorders may be caused by or result in structural changes in the brain, namely decreased hippocampal cell proliferation. |
2003-12-29 |
2023-08-12 |
Not clear |
| S H Fatemi, J A Earle, J M Stary, S Lee, J Sedgewic. Altered levels of the synaptosomal associated protein SNAP-25 in hippocampus of subjects with mood disorders and schizophrenia. Neuroreport. vol 12. issue 15. 2002-02-19. PMID:11711867. |
altered levels of the synaptosomal associated protein snap-25 in hippocampus of subjects with mood disorders and schizophrenia. |
2002-02-19 |
2023-08-12 |
human |
| M Banasr, M Hery, J M Brezun, A Daszut. Serotonin mediates oestrogen stimulation of cell proliferation in the adult dentate gyrus. The European journal of neuroscience. vol 14. issue 9. 2002-01-11. PMID:11722603. |
as 5-ht and oestrogen are involved in mood disorders, our data suggest that the positive regulation of cell proliferation and neuroplasticity by these two factors may contribute to restore hippocampal connectivity in depressive patients. |
2002-01-11 |
2023-08-12 |
rat |