| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Canbeyl. Sensorimotor modulation of mood and depression: an integrative review. Behavioural brain research. vol 207. issue 2. 2010-04-13. PMID:19913058. |
several lines of research on mood disorders reveal that depression involves a dysfunction in an affective fronto-limbic circuitry that involves the prefrontal cortices, the cingulate cortex, several limbic structures including the amygdala and the hippocampus, lower brainstem structures and the basal ganglia. |
2010-04-13 |
2023-08-12 |
Not clear |
| E Zambello, E Fuchs, N Abumaria, R Rygula, E Domenici, L Caberlott. Chronic psychosocial stress alters NPY system: different effects in rat and tree shrew. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 1. 2010-04-07. PMID:19846047. |
the results confirmed a major role for hippocampal and hypothalamic npy system in the pathophysiology of mood disorders. |
2010-04-07 |
2023-08-12 |
rat |
| P J Lucassen, P Meerlo, A S Naylor, A M van Dam, A G Dayer, E Fuchs, C A Oomen, B Czé. Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 20. issue 1. 2010-02-24. PMID:19748235. |
we discuss recent studies investigating factors that regulate neurogenesis with special emphasis on effects of stress, sleep disruption, exercise and inflammation, a group of seemingly unrelated factors that share at least two unifying properties, namely that they all regulate adult hippocampal neurogenesis and have all been implicated in the pathophysiology of mood disorders. |
2010-02-24 |
2023-08-12 |
Not clear |
| P J Lucassen, P Meerlo, A S Naylor, A M van Dam, A G Dayer, E Fuchs, C A Oomen, B Czé. Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 20. issue 1. 2010-02-24. PMID:19748235. |
a lasting reduction in neurogenesis following severe or chronic stress exposure, either in adult or early life, may represent impaired hippocampal plasticity and can contribute to the cognitive symptoms of depression, but is, by itself, unlikely to produce the full mood disorder. |
2010-02-24 |
2023-08-12 |
Not clear |
| Moshe Ba. A cognitive neuroscience hypothesis of mood and depression. Trends in cognitive sciences. vol 13. issue 11. 2010-02-23. PMID:19819753. |
the proposed framework has many implications, most notably for diagnosing and treating mood disorders such as depression; for elucidating the role of inhibition in the regulation of mood; for contextualizing adult hippocampal neurogenesis; and for a general, non-invasive improvement of well-being. |
2010-02-23 |
2023-08-12 |
Not clear |
| Amélie Soumier, Mounira Banasr, Sylviane Lortet, Frédérique Masmejean, Nathalie Bernard, Lydia Kerkerian-Le-Goff, Cecilia Gabriel, Mark J Millan, Elisabeth Mocaer, Annie Daszut. Mechanisms contributing to the phase-dependent regulation of neurogenesis by the novel antidepressant, agomelatine, in the adult rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 11. 2009-12-07. PMID:19571795. |
in adult rats, chronic agomelatine treatment enhanced cell proliferation and neurogenesis in the ventral hippocampus (vh), a region pertinent to mood disorders. |
2009-12-07 |
2023-08-12 |
rat |
| J S Dunham, J F W Deakin, F Miyajima, A Payton, C T Tor. Expression of hippocampal brain-derived neurotrophic factor and its receptors in Stanley consortium brains. Journal of psychiatric research. vol 43. issue 14. 2009-11-23. PMID:19376528. |
we therefore investigated whether levels of (pro)bdnf and receptor proteins, trkb and p75, are altered in hippocampus in schizophrenia and mood disorder and whether polymorphisms in each gene influenced protein expression. |
2009-11-23 |
2023-08-12 |
human |
| Peter Meerlo, Ralph E Mistlberger, Barry L Jacobs, H Craig Heller, Dennis McGint. New neurons in the adult brain: the role of sleep and consequences of sleep loss. Sleep medicine reviews. vol 13. issue 3. 2009-11-17. PMID:18848476. |
these effects of sleep loss may endanger hippocampal integrity, thereby leading to cognitive dysfunction and contributing to the development of mood disorders. |
2009-11-17 |
2023-08-12 |
rat |
| M Colla, F Schubert, M Bubner, J O Heidenreich, M Bajbouj, F Seifert, A Luborzewski, I Heuser, G Kronenber. Glutamate as a spectroscopic marker of hippocampal structural plasticity is elevated in long-term euthymic bipolar patients on chronic lithium therapy and correlates inversely with diurnal cortisol. Molecular psychiatry. vol 14. issue 7. 2009-09-10. PMID:18347601. |
while an excess of glucocorticoids is associated with hippocampal pathology in mood disorders, lithium exerts robust neuroprotective and neurotrophic effects. |
2009-09-10 |
2023-08-12 |
Not clear |
| Thomas Hauser, Fabienne Klaus, Hans-Peter Lipp, Irmgard Amrei. No effect of running and laboratory housing on adult hippocampal neurogenesis in wild caught long-tailed wood mouse. BMC neuroscience. vol 10. 2009-06-30. PMID:19419549. |
studies of adult hippocampal neurogenesis (ahn) in laboratory rodents have raised hopes for therapeutic interventions in neurodegenerative diseases and mood disorders, as ahn can be modulated by physical exercise, stress and environmental changes in these animals. |
2009-06-30 |
2023-08-12 |
mouse |
| Amanda J Law, Qi Pei, Mary Walker, Helen Gordon-Andrews, Cyndi Shannon Weickert, Joram Feldon, Christopher R Pryce, Paul J Harriso. Early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 6. 2009-06-17. PMID:18615010. |
early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder. |
2009-06-17 |
2023-08-12 |
monkey |
| Amanda J Law, Qi Pei, Mary Walker, Helen Gordon-Andrews, Cyndi Shannon Weickert, Joram Feldon, Christopher R Pryce, Paul J Harriso. Early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 6. 2009-06-17. PMID:18615010. |
in mood disorder, early stressors including parental separation are vulnerability factors, and hippocampal involvement is prominent. |
2009-06-17 |
2023-08-12 |
monkey |
| Amanda J Law, Qi Pei, Mary Walker, Helen Gordon-Andrews, Cyndi Shannon Weickert, Joram Feldon, Christopher R Pryce, Paul J Harriso. Early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 6. 2009-06-17. PMID:18615010. |
here we examined the expression of eight genes, each implicated in neural plasticity and in the pathophysiology of mood disorder, in the hippocampus of these same adolescent marmosets, relative to their normally reared sibling controls. |
2009-06-17 |
2023-08-12 |
monkey |
| Amanda J Law, Qi Pei, Mary Walker, Helen Gordon-Andrews, Cyndi Shannon Weickert, Joram Feldon, Christopher R Pryce, Paul J Harriso. Early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 6. 2009-06-17. PMID:18615010. |
equally, the negative results suggest that other features of mood disorder, such as decreased hippocampal volume and bdnf expression, are related to different aspects of the pathophysiological process. |
2009-06-17 |
2023-08-12 |
monkey |
| Gerard Sanacor. New understanding of mechanisms of action of bipolar medications. The Journal of clinical psychiatry. vol 69 Suppl 5. 2009-03-30. PMID:19265637. |
patients with mood disorders have been found to exhibit evidence of neuroplastic changes, such as reductions in hippocampal and cortical volume, glial and neuronal cell density, and levels of brain-derived neurotrophic factor; chronic stress, a major precipitator of depression, has been shown to cause many of the same neuroplastic changes to occur in animal models. |
2009-03-30 |
2023-08-12 |
Not clear |
| Lara G Chepenik, Carolyn Fredericks, Xenophon Papademetris, Linda Spencer, Cheryl Lacadie, Fei Wang, Brian Pittman, James S Duncan, Lawrence H Staib, Ronald S Duman, Joel Gelernter, Hilary P Blumber. Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 4. 2009-03-23. PMID:18704093. |
brain-derived neurotrophic growth factor (bdnf) protein is associated with hippocampal development and plasticity, and in mood disorder pathophysiology. |
2009-03-23 |
2023-08-12 |
human |
| Gerard Sanacor. Reviewing medications for bipolar disorder: understanding the mechanisms of action. The Journal of clinical psychiatry. vol 70. issue 1. 2009-03-05. PMID:19222977. |
patients with mood disorders have been found to have neuroplastic changes, including reductions in hippocampal volume, glial and neuronal cell density, and brain-derived neurotrophic factor. |
2009-03-05 |
2023-08-12 |
Not clear |
| Alessia Bachis, Maria Idalia Cruz, Rachel L Nosheny, Italo Mocchett. Chronic unpredictable stress promotes neuronal apoptosis in the cerebral cortex. Neuroscience letters. vol 442. issue 2. 2008-12-12. PMID:18621098. |
stress-mediated loss of synaptogenesis in the hippocampus appears to play a role in depressive and mood disorders. |
2008-12-12 |
2023-08-12 |
rat |
| R Silva, A R Mesquita, J Bessa, J C Sousa, I Sotiropoulos, P Leão, O F X Almeida, N Sous. Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3beta. Neuroscience. vol 152. issue 3. 2008-07-21. PMID:18291594. |
although the mechanisms implicated in the genesis of mood disorders are still unclear, stress is known to predispose to depression, and recently, studies have related hippocampal neurogenesis and apoptosis to depression. |
2008-07-21 |
2023-08-12 |
rat |
| E M Wexler, D H Geschwind, T D Palme. Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation. Molecular psychiatry. vol 13. issue 3. 2008-04-17. PMID:17968353. |
neural stem cells give rise to new hippocampal neurons throughout adulthood, and defects in neurogenesis may predispose an individual to mood disorders, such as major depression. |
2008-04-17 |
2023-08-12 |
Not clear |