| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Chen, D Dowlatshahi, G M MacQueen, J F Wang, L T Youn. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biological psychiatry. vol 50. issue 4. 2001-11-01. PMID:11522260. |
this study was designed to test whether the diagnosis of a mood disorder, or treatment with an antidepressant or mood stabilizer was associated with changes in hippocampal bdnf in postmortem brain. |
2001-11-01 |
2023-08-12 |
human |
| L E Haynes, M R Griffiths, R E Hyde, D J Barber, I J Mitchel. Dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders. Neuroscience. vol 104. issue 1. 2001-07-12. PMID:11311531. |
dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders. |
2001-07-12 |
2023-08-12 |
human |
| L E Haynes, M R Griffiths, R E Hyde, D J Barber, I J Mitchel. Dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders. Neuroscience. vol 104. issue 1. 2001-07-12. PMID:11311531. |
similar damage was seen in the hippocampus, with the dentate gyrus and ca1 and ca3 subfields being particularly vulnerable.equivalent corticosteroid-induced neuronal damage may occur in mood disorders, where the levels of endogenous corticosteroids are often raised. |
2001-07-12 |
2023-08-12 |
human |
| D Dowlatshahi, G MacQueen, J F Wang, B Chen, L T Youn. Increased hippocampal supragranular Timm staining in subjects with bipolar disorder. Neuroreport. vol 11. issue 17. 2001-03-01. PMID:11117489. |
biochemical and structural abnormalities have been reported in hippocampus of subjects with mood disorders. |
2001-03-01 |
2023-08-12 |
human |
| J Semba, H Watanabe, T Suhara, N Akanum. Chronic lithium chloride injection increases glucocorticoid receptor but not mineralocorticoid receptor mRNA expression in rat brain. Neuroscience research. vol 38. issue 3. 2000-12-22. PMID:11070198. |
since the hippocampus and pvn mediate negative feedback regulation of the hpa axis, an increased expression of gr mrna in these regions may normalize hpa axis activity in mood disorders. |
2000-12-22 |
2023-08-12 |
rat |
| M P Laakso, O Vaurio, L Savolainen, E Repo, H Soininen, H J Aronen, J Tiihone. A volumetric MRI study of the hippocampus in type 1 and 2 alcoholism. Behavioural brain research. vol 109. issue 2. 2000-06-21. PMID:10762687. |
particularly in studies on schizophrenia and mood disorders, findings regarding the hippocampal involvement have been most controversial. |
2000-06-21 |
2023-08-12 |
human |
| E S Brown, A J Rush, B S McEwe. Hippocampal remodeling and damage by corticosteroids: implications for mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 4. 1999-10-08. PMID:10481830. |
hippocampal remodeling and damage by corticosteroids: implications for mood disorders. |
1999-10-08 |
2023-08-12 |
human |
| E S Brown, A J Rush, B S McEwe. Hippocampal remodeling and damage by corticosteroids: implications for mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 4. 1999-10-08. PMID:10481830. |
thus, hippocampal dysfunction could account for both the memory impairment and neuroendocrine abnormalities found in mood disorders. |
1999-10-08 |
2023-08-12 |
human |
| E S Brown, A J Rush, B S McEwe. Hippocampal remodeling and damage by corticosteroids: implications for mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 4. 1999-10-08. PMID:10481830. |
this review examines data on the role of corticosteroids in hippocampal remodeling and atrophy in patients with mood disorders. |
1999-10-08 |
2023-08-12 |
human |
| J Lehrner, R Kalchmayr, W Serles, A Olbrich, E Pataraia, S Aull, J Bacher, F Leutmezer, G Gröppel, L Deecke, C Baumgartne. Health-related quality of life (HRQOL), activity of daily living (ADL) and depressive mood disorder in temporal lobe epilepsy patients. Seizure. vol 8. issue 2. 1999-09-20. PMID:10222299. |
furthermore, we investigated the association of the laterality of seizure onset zone and absence/presence of hippocampal atrophy and/or sclerosis (ha/hs) with measures of hrqol, activities of daily living (adl) and depressive mood disorder. |
1999-09-20 |
2023-08-12 |
Not clear |
| F Chaoulof. Regulation of 5-HT receptors by corticosteroids: where do we stand? Fundamental & clinical pharmacology. vol 9. issue 3. 1995-11-21. PMID:7557817. |
in keeping with the respective effects of stressful stimuli and psychotropic drugs upon the hpa axis and central serotonergic systems, it is likely that these corticosteroid-5-ht1a receptor interactions in the hippocampus have consequences in the pathophysiology of mood disorders. |
1995-11-21 |
2023-08-12 |
rat |
| L Khaitan, J R Calabrese, C A Stockmeie. Effects of chronic treatment with valproate on serotonin-1A receptor binding and function. Psychopharmacology. vol 113. issue 3-4. 1995-03-20. PMID:7862872. |
based on these animal studies in frontal cortex and hippocampus, the therapeutic benefit of valproate in mood disorders does not appear to involve adaptive changes in serotonin-1a, serotonin-2 or beta-adrenergic receptor number. |
1995-03-20 |
2023-08-12 |
rat |
| E D Weiner, A M Mallat, D F Papolos, H M Lachma. Acute lithium treatment enhances neuropeptide Y gene expression in rat hippocampus. Brain research. Molecular brain research. vol 12. issue 1-3. 1992-04-13. PMID:1372067. |
we find that acute treatment with lithium, resulting in serum levels that are within the therapeutic range effective in patients with mood disorders, significantly enhances basal expression of the npy gene in rat hippocampus. |
1992-04-13 |
2023-08-11 |
rat |