| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Pina Serra, Laura Poddighe, Marianna Boi, Francesco Sanna, M Antonietta Piludu, M Giuseppa Corda, Osvaldo Giorgi, Marina Quart. Expression of BDNF and trkB in the hippocampus of a rat genetic model of vulnerability (Roman low-avoidance) and resistance (Roman high-avoidance) to stress-induced depression. Brain and behavior. vol 7. issue 10. 2018-07-09. PMID:29075579. |
besides the monoamine hypothesis of depression, there is evidence that alterations in neuronal plasticity in the hippocampus and other brain areas are critically involved in the pathophysiology of mood disorders. |
2018-07-09 |
2023-08-13 |
rat |
| Gonzalo García-Rojo, Cristóbal Fresno, Natalia Vilches, Gabriela Díaz-Véliz, Sergio Mora, Felipe Aguayo, Aníbal Pacheco, Nicolás Parra-Fiedler, Claudio S Parra, Paulina S Rojas, Macarena Tejos, Esteban Aliaga, Jenny L Fiedle. The ROCK Inhibitor Fasudil Prevents Chronic Restraint Stress-Induced Depressive-Like Behaviors and Dendritic Spine Loss in Rat Hippocampus. The international journal of neuropsychopharmacology. vol 20. issue 4. 2018-05-18. PMID:27927737. |
dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. |
2018-05-18 |
2023-08-13 |
rat |
| Vera Chesnokova, Robert N Pechnick, Kolja Wawrowsk. Chronic peripheral inflammation, hippocampal neurogenesis, and behavior. Brain, behavior, and immunity. vol 58. 2018-01-17. PMID:26802985. |
adult hippocampal neurogenesis is involved in memory and learning, and disrupted neurogenesis is implicated in cognitive impairment and mood disorders, including anxiety and depression. |
2018-01-17 |
2023-08-13 |
human |
| b' Ivan Zaletel, Dragana Filipovi\\xc4\\x87, Nela Pu\\xc5\\xa1ka\\xc5\\xa. Chronic stress, hippocampus and parvalbumin-positive interneurons: what do we know so far? Reviews in the neurosciences. vol 27. issue 4. 2018-01-02. PMID:26751865.' |
the hippocampal gabaergic parvalbumin-positive (pv+) interneurons represent an especially vulnerable population of neurons in chronic stress, which may be of key importance in the development of mood disorders. |
2018-01-02 |
2023-08-13 |
Not clear |
| B Cao, I C Passos, B Mwangi, H Amaral-Silva, J Tannous, M-J Wu, G B Zunta-Soares, J C Soare. Hippocampal subfield volumes in mood disorders. Molecular psychiatry. vol 22. issue 9. 2017-11-16. PMID:28115740. |
hippocampal subfield volumes in mood disorders. |
2017-11-16 |
2023-08-13 |
human |
| B Cao, I C Passos, B Mwangi, H Amaral-Silva, J Tannous, M-J Wu, G B Zunta-Soares, J C Soare. Hippocampal subfield volumes in mood disorders. Molecular psychiatry. vol 22. issue 9. 2017-11-16. PMID:28115740. |
volume reduction and shape abnormality of the hippocampus have been associated with mood disorders. |
2017-11-16 |
2023-08-13 |
human |
| B Cao, I C Passos, B Mwangi, H Amaral-Silva, J Tannous, M-J Wu, G B Zunta-Soares, J C Soare. Hippocampal subfield volumes in mood disorders. Molecular psychiatry. vol 22. issue 9. 2017-11-16. PMID:28115740. |
it is known that cellular and molecular mechanisms associated with mood disorders may be localized to specific hippocampal subfields. |
2017-11-16 |
2023-08-13 |
human |
| B Cao, I C Passos, B Mwangi, H Amaral-Silva, J Tannous, M-J Wu, G B Zunta-Soares, J C Soare. Hippocampal subfield volumes in mood disorders. Molecular psychiatry. vol 22. issue 9. 2017-11-16. PMID:28115740. |
thus, it is necessary to investigate the link between the in vivo hippocampal subfield volumes and specific mood disorders, such as bipolar disorder (bd) and major depressive disorder (mdd). |
2017-11-16 |
2023-08-13 |
human |
| B Cao, I C Passos, B Mwangi, H Amaral-Silva, J Tannous, M-J Wu, G B Zunta-Soares, J C Soare. Hippocampal subfield volumes in mood disorders. Molecular psychiatry. vol 22. issue 9. 2017-11-16. PMID:28115740. |
these results indicated that among the mood disorders the hippocampal subfields were more affected in bd-i compared with bd-ii and mdd, and manic episodes had focused progressive effect on the ca2/3 and ca4 and hippocampal tail. |
2017-11-16 |
2023-08-13 |
human |
| L Zhou, S L Ma, P K K Yeung, Y H Wong, K W K Tsim, K F So, L C W Lam, S K Chun. Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac. Translational psychiatry. vol 6. issue 9. 2017-11-07. PMID:27598965. |
taken together, epac2 gene polymorphism is a putative risk factor for mood disorders in ad patients in part by affecting the hippocampal neurogenesis. |
2017-11-07 |
2023-08-13 |
mouse |
| Katarzyna Młyniec, Gabriela Starowicz, Magdalena Gaweł, Ewelina Frąckiewicz, Gabriel Nowa. Potential antidepressant-like properties of the TC G-1008, a GPR39 (zinc receptor) agonist. Journal of affective disorders. vol 201. 2017-10-02. PMID:27235821. |
we also found hippocampal gpr39 and brain-derived neurotrophic factor (bdnf) up-regulation following administration of the gpr39 agonist, which may be undiscovered so far as a possible novel agent in the treatment of mood disorders. |
2017-10-02 |
2023-08-13 |
mouse |
| Sara Poletti, Clara Locatelli, Andrea Falini, Cristina Colombo, Francesco Benedett. Adverse childhood experiences associate to reduced glutamate levels in the hippocampus of patients affected by mood disorders. Progress in neuro-psychopharmacology & biological psychiatry. vol 71. 2017-08-30. PMID:27449360. |
adverse childhood experiences associate to reduced glutamate levels in the hippocampus of patients affected by mood disorders. |
2017-08-30 |
2023-08-13 |
Not clear |
| Sara Poletti, Clara Locatelli, Andrea Falini, Cristina Colombo, Francesco Benedett. Adverse childhood experiences associate to reduced glutamate levels in the hippocampus of patients affected by mood disorders. Progress in neuro-psychopharmacology & biological psychiatry. vol 71. 2017-08-30. PMID:27449360. |
adverse childhood experiences (ace) can possibly permanently alter the stress response system, affect the glutamatergic system and influence hippocampal volume in mood disorders. |
2017-08-30 |
2023-08-13 |
Not clear |
| Sara Poletti, Clara Locatelli, Andrea Falini, Cristina Colombo, Francesco Benedett. Adverse childhood experiences associate to reduced glutamate levels in the hippocampus of patients affected by mood disorders. Progress in neuro-psychopharmacology & biological psychiatry. vol 71. 2017-08-30. PMID:27449360. |
the aim of the study is to investigate the association between glutamate levels in the hippocampus, measured through single proton magnetic resonance spectroscopy (1h-mrs), and ace in patients affected by mood disorders and healthy controls. |
2017-08-30 |
2023-08-13 |
Not clear |
| A Vania Apkarian, Amelia A Mutso, Maria V Centeno, Lixin Kan, Melody Wu, Marjorie Levinstein, Ghazal Banisadr, Kevin T Gobeske, Richard J Miller, Jelena Radulovic, René Hen, John A Kessle. Role of adult hippocampal neurogenesis in persistent pain. Pain. vol 157. issue 2. 2016-10-13. PMID:26313405. |
the full role of adult hippocampal neurogenesis (ahn) remains to be determined, yet it is implicated in learning and emotional functions, and is disrupted in negative mood disorders. |
2016-10-13 |
2023-08-13 |
mouse |
| Elise C Cope, Deborah R Morris, Shannon D Gower-Winter, Naomi C Brownstein, Cathy W Levenso. Effect of zinc supplementation on neuronal precursor proliferation in the rat hippocampus after traumatic brain injury. Experimental neurology. vol 279. 2016-09-06. PMID:26902472. |
there is great deal of debate about the possible role of adult-born hippocampal cells in the prevention of depression and related mood disorders. |
2016-09-06 |
2023-08-13 |
rat |
| Vincent Vialou, Mackenzie Thibault, Sophia Kaska, Sarah Cooper, Paula Gajewski, Andrew Eagle, Michelle Mazei-Robison, Eric J Nestler, A J Robiso. Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress. Neuropharmacology. vol 99. 2016-08-24. PMID:26164345. |
these data suggest that nac, pfc, and hippocampus may present useful targets for directed intervention in mood disorders (ie, brain stimulation or gene therapy), and that determining the gene targets of fosb-mediated transcription in these brain regions in response to fluoxetine may yield novel inroads for pharmaceutical intervention in depressive disorders. |
2016-08-24 |
2023-08-13 |
mouse |
| Sanghee Yun, Michael H Donovan, Michele N Ross, Devon R Richardson, Robin Reister, Laure A Farnbauch, Stephanie J Fischer, Dieter Riethmacher, Howard K Gershenfeld, Diane C Lagace, Amelia J Eisc. Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreERT2/Diphtheria Toxin Fragment A Transgenic Mice. PloS one. vol 11. issue 1. 2016-08-09. PMID:26795203. |
depression and anxiety involve hippocampal dysfunction, but the specific relationship between these mood disorders and adult hippocampal dentate gyrus neurogenesis remains unclear. |
2016-08-09 |
2023-08-13 |
mouse |
| Francesco Margari, Maria Giuseppina Petruzzelli, Rossana Mianulli, Maria Gloria Campa, Adriana Pastore, Marilina Tampoi. Circulating anti-brain autoantibodies in schizophrenia and mood disorders. Psychiatry research. vol 230. issue 2. 2016-06-24. PMID:26548982. |
the aim of this study was to assay organ-specific and non organ-specific circulating autoantibodies in schizophrenia, mood disorders and healthy controls; among organ-specific autoantibodies we focused on different fluorescence patterns of anti-brain autoantibodies against rat and monkey's sections of hippocampus, hypothalamus and cerebellum. |
2016-06-24 |
2023-08-13 |
rat |
| Francesco Margari, Maria Giuseppina Petruzzelli, Rossana Mianulli, Maria Gloria Campa, Adriana Pastore, Marilina Tampoi. Circulating anti-brain autoantibodies in schizophrenia and mood disorders. Psychiatry research. vol 230. issue 2. 2016-06-24. PMID:26548982. |
we found a significant difference for circulating autoantibodies to hypothalamus, hippocampus and cerebellum and for anti-nuclear autoantibodies in both schizophrenia and mood disorders when compared to the control group. |
2016-06-24 |
2023-08-13 |
rat |